Abstract：
BACKGROUND:Enterobacter cloacae has become a common cause of nosocomial infections. This study was designed to investigate the pattern of spread of E cloacae during an outbreak in a neonatal intensive care unit. METHODS:Enterobacterial repetitive intergenic consensus polymerase chain reaction was used to examine 111 E cloacae isolates from 17 patients, including 81 from surveillance cultures, 23 from endotracheal tubes, 3 from eyes, and 1 each from blood, urine, skin, and throat. Antibiotic susceptibility profiles were also obtained. RESULTS:Infection with E cloacae resulted from endogenous bacteria and from horizontal transmission. One group of 61 isolates, a third of which were obtained from clinical specimens, was uniformly susceptible to imipenem and ciprofloxacin only. A second group of 50 isolates, only 18% of which were obtained from clinical specimens, was susceptible to all antibiotics tested except for aminopenicillins and first-generation cephalosporins. CONCLUSION:These data indicate that (1) patient-to-patient spread is an important cause of E cloacae infection in the neonatal intensive care unit and (2) highly antibiotic-resistant E cloacae may emerge during an outbreak.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Peters SM,Bryan J,Cole MFsubject
Has Abstractpub_date
2000-04-01 00:00:00pages
123-9issue
2eissn
0196-6553issn
1527-3296pii
S0196-6553(00)90020-8journal_volume
28pub_type
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章,meta分析
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章,评审
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章
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更新日期：2005-10-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章,评审
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journal_title：American journal of infection control
pub_type： 杂志文章
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