Vascular complications in young Asian Indian patients with type 1 diabetes mellitus.

Abstract:

:To determine the prevalence of micro vascular and macro vascular complications in Asian Indian Type 1 diabetic subjects. There has been no major report on the prevalence of vascular complications in Type 1 diabetic patients in India. This study was done in Type 1 diabetic patients, aged < or =20 years at diagnosis of diabetes (n=617, M:F 322:295) with a minimum of 3 year follow-up. Standard diagnostic methodologies were used to test for micro vascular and macro vascular complications of diabetes. Retinopathy was detected in 13. 4% (background diabetic retinopathy 11.2%, proliferative diabetic retinopathy 1.9%, preproliferative 0.31%, maculopathy was seen in 13.3% of retinopathy cases), nephropathy in 7.1%, sensory neuropathy in 3.0%, ischaemic heart disease in 0.5% and peripheral vascular disease in 0.5% of the study subjects. Duration of diabetes showed positive association with retinopathy, nephropathy and neuropathy. Average glycosylated haemoglobin values, at follow up showed an association with retinopathy. Although the glycaemic control was suboptimal in the study group, prevalences of all complications, especially macro vascular complications were lower in Type 1 diabetic patients in this ethnic group, in comparison with the European or American counterparts.

authors

Ramachandran A,Snehalatha C,Sasikala R,Satyavani K,Vijay V

doi

10.1016/s0168-8227(99)00134-5

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

51-6

issue

1

eissn

0168-8227

issn

1872-8227

pii

S0168822799001345

journal_volume

48

pub_type

杂志文章
  • Aggravation of albuminuria by metabolic syndrome in type 2 diabetic Asian subjects.

    abstract:AIMS:We investigated the relationship of urinary albumin excretion (UAE) to metabolic syndrome and type 2 diabetes in Asian. METHODS:A total of 446 subjects (187 without diabetes and 259 with type 2 diabetes) were enrolled in this study. The components of metabolic syndrome, high sensitivity C-reactive protein (hs-CRP...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.05.010

    authors: Lee IT,Huang CN,Lee WJ,Lee HS,Sheu WH

    更新日期:2008-09-01 00:00:00

  • Fibrillogenic amylin evokes the apoptosis of human mesangial cells.

    abstract:OBJECTIVE:To explore the apoptotic role of amylin on human mesangial cell (MC). MATERIALS AND METHODS:Primarily cultured human MCs were applied and treated with fresh amylin preparation. Human MCs were identified by the morphology and immunofluorescence staining. The apoptotic cells were determined by ultrastructure c...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.02.018

    authors: Peng A,Liu ZH,Zhou H,Zhu MY,Li LS

    更新日期:2007-10-01 00:00:00

  • The effectiveness and safety of beginning insulin aspart together with basal insulin in people with type 2 diabetes in non-Western nations: results from the A₁chieve observational study.

    abstract:AIMS:The aim of this A₁chieve sub-group analysis was to examine populations beginning insulin aspart together with any basal insulin, all ± oral glucose lowering drugs: insulin aspart added to existing basal insulin (n=519); switched from biphasic insulin (n=947); switched from NPH plus human meal-time insulins (n=586)...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2013.06.005

    authors: Home PD,Latif ZA,González-Gálvez G,Prusty V,Hussein Z

    更新日期:2013-09-01 00:00:00

  • Impact of nonadherence on complication risks and healthcare costs in patients newly-diagnosed with diabetes.

    abstract:AIMS:To investigate the association between nonadherence to diabetes treatment and the occurrence of diabetes complications. METHODS:Our study retrospectively identified adherence and nonadherence to diabetes treatment in patients during the first year of observation after new diagnoses of type 2 diabetes enrolled in ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.11.007

    authors: Fukuda H,Mizobe M

    更新日期:2017-01-01 00:00:00

  • Transplantation of discordant pig islet xenografts in diabetic rats.

    abstract::Xenotransplantation of pig islets under the kidney capsule (KC) of diabetic rats was performed. Natural preformed ACI rat anti-pig leukocytotoxicity, leukoagglutination and hemagglutination antibody titers ranged from Neat-1: 16, 1:8-1:32 and 1:128-1:256, respectively (n = 14). Normal ACI sera were non-toxic to pig is...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(92)90025-m

    authors: Tze WJ,Tai J,Cheung SS

    更新日期:1992-03-01 00:00:00

  • Cardiovascular risk factors and LDL subfraction profile in Type 2 diabetes mellitus subjects with good glycaemic control.

    abstract:OBJECTIVES:To compare cardiovascular risk factors and LDL particle size in well-controlled Type 2 diabetes mellitus and normal subjects. METHODS:Ninety-three Type 2 diabetic males and 186 age-matched, male controls were studied. Glycaemic control was stable for at least 3 months prior to recruitment. None were on insu...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00211-4

    authors: Tan CE,Chew LS,Chio LF,Tai ES,Lim HS,Lim SC,Jayakumar L,Eng HK,Packard CJ

    更新日期:2001-02-01 00:00:00

  • Improving diabetes care: multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia--the CARRS multi-center translation trial.

    abstract:AIMS:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and P...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.diabres.2012.09.023

    authors: CARRS Trial Writing Group.,Shah S,Singh K,Ali MK,Mohan V,Kadir MM,Unnikrishnan AG,Sahay RK,Varthakavi P,Dharmalingam M,Viswanathan V,Masood Q,Bantwal G,Khadgawat R,Desai A,Sethi BK,Shivashankar R,Ajay VS,Reddy KS,Na

    更新日期:2012-11-01 00:00:00

  • HLA-DQB1 genotypes and islet cell autoantibodies against GAD65 and IA-2 in relation to development of diabetes post partum in women with gestational diabetes mellitus.

    abstract:AIMS:To study HLA-DQB1 genes and islet cell autoantibodies against glutamic acid decarboxylase 65 (GADA) and insulinoma antigen-2 (IA-2A) in relation to diabetes post partum in mothers with diagnosed gestational diabetes mellitus (GDM). METHODS:During 2003-2004, women undergoing a 75 g oral glucose tolerance test (OGT...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2011.10.037

    authors: Papadopoulou A,Lynch KF,Anderberg E,Landin-Olsson M,Hansson I,Agardh CD,Lernmark Å,Berntorp K

    更新日期:2012-02-01 00:00:00

  • Enhanced vascular production of superoxide in OLETF rat after the onset of hyperglycemia.

    abstract::This study was aimed to characterize the vascular production of superoxide in Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a model of type 2 diabetes. The nitroblue tetrazolium staining in the aorta from old (30 weeks) OLETF rat was more prominent than that of age-matched control (LETO) rat, which was significantly ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(02)00278-4

    authors: Kim IJ,Kim YK,Son SM,Hong KW,Kim CD

    更新日期:2003-04-01 00:00:00

  • Insulin resistance in Brazilian adolescent girls: association with overweight and metabolic disorders.

    abstract::We assessed the association between insulin resistance, overweight and metabolic disorders in a probabilistic sample of 388, 12-19-year-old girls from public schools in Niterói, Rio de Janeiro State, Brazil. Insulin resistance was determined using Homeostatic Model Assessment-Insulin Resistance (HOMA-IR). Overweight a...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2006.03.018

    authors: Alvarez MM,Vieira AC,Moura AS,da Veiga GV

    更新日期:2006-11-01 00:00:00

  • Exercise training in Otsuka Long-Evans Tokushima Fatty rat, a model of spontaneous non-insulin-dependent diabetes mellitus: effects on the B-cell mass, insulin content and fibrosis in the pancreas.

    abstract::The effects of exercise on alterations in the amount of B-cell mass, insulin content and fibrous tissue present in the pancreas were examined for a diabetic state induced by a 70% pancreatectomy and a prediabetic state in Otsuka Long-Evans Tokushima Fatty (OLETF) rat, a model for the spontaneous development of non-ins...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(96)01357-5

    authors: Shima K,Zhu M,Noma Y,Mizuno A,Murakami T,Sano T,Kuwajima M

    更新日期:1997-02-01 00:00:00

  • Glucose transporter levels in a male spontaneous non-insulin-dependent diabetes mellitus rat of the Otsuka Long-Evans Tokushima Fatty strain.

    abstract::Otsuka Long-Evans Tokushima Fatty (OLETF) rats are a new strain of spontaneous non-insulin-dependent diabetes mellitus (NIDDM) models. To evaluate the role of glucose transporters (GLUT) in the development of diabetes in this model, we examined the action of insulin on the translocation of GLUT4 and GLUT1 in isolated ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(97)00101-0

    authors: Toide K,Man ZW,Asahi Y,Sato T,Nakayama N,Noma Y,Oka Y,Shima K

    更新日期:1997-12-01 00:00:00

  • Association of psychosocial factors with anxiety and depressive symptoms in Chinese patients with type 2 diabetes.

    abstract:OBJECTIVE:To investigate association of psychosocial factors with anxiety and depressive symptoms in Chinese type 2 diabetes patients. METHODS:Three hundred and four type 2 diabetes patients were inquired with a structured questionnaire about socio-demographic characteristics, psychological stress, coping styles, soci...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.10.014

    authors: Zhang CX,Chen YM,Chen WQ

    更新日期:2008-03-01 00:00:00

  • Clinical experience with BIAsp 30: results from the Indonesian cohort of the international A₁chieve study.

    abstract:AIM:To evaluate the safety and effectiveness of biphasic insulin aspart 30 (BIAsp 30) in Indonesian patients with type 2 diabetes (T2D) as part of the 24-week, international, prospective, non-interventional A₁chieve study. METHODS:Indonesian patients who started BIAsp 30 were included. Safety and efficacy was measured...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,多中心研究

    doi:10.1016/S0168-8227(13)70011-1

    authors: Soewondo P,Pramono RB,Langi YA,Soetedjo NN,Kshanti IA

    更新日期:2013-04-01 00:00:00

  • Complete remission of diabetic nephropathy in a type 1 diabetic patient with near-nephrotic range proteinuria and reduced renal function.

    abstract::There is scant knowledge on the changes in renal histological findings in type 1 diabetic patients those initially had nephrotic proteinuria and decreased renal function and later had complete remission of diabetic nephropathy by multifactorial treatment (MFT). A 44-year-old Japanese type 1 diabetic woman (duration of...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.10.019

    authors: Haraguchi K,Hara S,Ubara Y,Tanaka S,Nukui I,Shimura H,Ohashi K,Kobayashi T

    更新日期:2009-03-01 00:00:00

  • Long-term therapeutic effects of voglibose, a potent intestinal alpha-glucosidase inhibitor, in spontaneous diabetic GK rats.

    abstract::The effect of long-term (6 months) administration of voglibose in a dietary mixture (10 ppm) on intestinal disaccharidase activity was examined in non obese type 2 diabetes model Goto-Kakizaki (GK) rats. The postprandial blood glucose level in voglibose-treated GK rats was significantly lower than in untreated GK rats...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(02)00241-3

    authors: Yasuda K,Shimowada K,Uno M,Odaka H,Adachi T,Shihara N,Suzuki N,Tamon A,Nagashima K,Hosokawa M,Tsuda K,Seino Y

    更新日期:2003-02-01 00:00:00

  • Absence of the Gly40-ser mutation in the glucagon receptor gene in Japanese subjects with NIDDM.

    abstract::Recent studies have shown both association and linkage between a Gly40-Ser mutation in the glucagon receptor gene and NIDDM in French patients with familial NIDDM. This mutation was present in heterozygous form in 4.6% of diabetic probands but only 1% of the French population, suggesting that it was an important risk ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/0168-8227(96)01284-3

    authors: Ogata M,Iwasaki N,Ohgawara H,Karibe S,Omori Y

    更新日期:1996-07-01 00:00:00

  • Perceptions about professionally and non-professionally trained hypoglycemia detection dogs.

    abstract:AIMS:Patients with diabetes increasingly have questions about diabetes alert dogs. This study evaluated perceptions about dogs trained professionally or otherwise to detect glucose levels. METHODS:A link to a survey about glucose detecting dogs was announced on diabetes websites. RESULTS:135 persons responded, with 6...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2015.05.023

    authors: Petry NM,Wagner JA,Rash CJ,Hood KK

    更新日期:2015-08-01 00:00:00

  • Serum osteoprotegerin is associated with carotid intima media thickness in women with previous gestational diabetes.

    abstract::Circulating levels of osteoprotegerin (OPG) have been shown to be increased in patients with cardiovascular disorders and diabetes. The aim of this study was to determine serum OPG levels in women with previous gestational diabetes (GDM), and to investigate the relationship between OPG and carotid intima media thickne...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2008.07.014

    authors: Akinci B,Demir T,Celtik A,Baris M,Yener S,Ozcan MA,Yuksel F,Secil M,Yesil S

    更新日期:2008-11-01 00:00:00

  • Aminoguanidine inhibits albuminuria, but not the formation of advanced glycation end-products in skin collagen of diabetic rats.

    abstract::Aminoguanidine, an inhibitor of advanced glycation reactions in vitro, inhibits the development of diabetic complications in animal models of diabetes, suggesting that it acts by inhibition of advanced glycation reactions in vivo. However, effects of aminoguanidine on the formation of specific advanced glycation end-p...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(98)00121-1

    authors: Degenhardt TP,Fu MX,Voss E,Reiff K,Neidlein R,Strein K,Thorpe SR,Baynes JW,Reiter R

    更新日期:1999-02-01 00:00:00

  • Relationship of abdominal fat with metabolic disorders in diabetes mellitus patients.

    abstract::In this study, we examined the relationships of the fat distribution with the clinical parameters, microangiopathy, and coagulation disorders in Japanese diabetic patients, distinguishing between males and females. To investigate these relationships, the clinical parameters of the patients were compared with the total...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(01)00294-7

    authors: Asakawa H,Tokunaga K,Kawakami F

    更新日期:2002-02-01 00:00:00

  • Outcomes and lessons from the PROactive study.

    abstract::Beyond improvement of glucose control, thiazolidinediones exert pleiotropic effects, which may contribute to some cardiovascular protection. PROactive ("PROspective pioglitAzone Clinical Trial In macroVascular Events") has provided valuable, although controversial, information on the impact of pioglitazone on cardiova...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章,评审

    doi:10.1016/j.diabres.2012.09.001

    authors: Scheen AJ

    更新日期:2012-11-01 00:00:00

  • A 15 year follow-up study of patients with non-insulin dependent diabetes mellitus (NIDDM) in Osaka, Japan. Long-term prognosis and causes of death.

    abstract::A 15 year follow-up study of diabetic patients was performed in Osaka, Japan. The subjects studied were 1939 patients with non-insulin dependent diabetes mellitus (NIDDM), of whom 1000 (51.5%) were alive, 880 (45.4%) had died and 59 (3.0%) were untraceable at the end of 1993. The mortality rate per 1000 person-years o...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(96)01329-0

    authors: Sasaki A,Uehara M,Horiuchi N,Hasegawa K,Shimizu T

    更新日期:1996-09-01 00:00:00

  • Insulin administration may trigger pancreatic beta-cell destruction in patients with type 2 diabetes.

    abstract::Insulin administration causes various types of immune response to insulin. However, there have been no reports that insulin administration triggers pancreatic beta-cell destruction in diabetic patients. We evaluated three patients who had suffered from type 2 diabetes or impaired glucose tolerance for 5-30 years. Afte...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2007.08.031

    authors: Nakamura M,Nishida W,Yamada Y,Chujo D,Watanabe Y,Imagawa A,Hanafusa T,Kawasaki E,Onuma H,Osawa H,Makino H

    更新日期:2008-02-01 00:00:00

  • A case of chronic hepatitis C developing insulin-dependent diabetes mellitus associated with various autoantibodies during interferon therapy.

    abstract::We report a case of chronic hepatitis C presenting insulin-dependent diabetes mellitus (IDDM) associated with various autoantibodies including possible anti-insulin receptor antibody (AIRA) during interferon (IFN) therapy. A 57-year-old man having chronic hepatitis C virus (HCV) infection with chronic thyroiditis rece...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/s0168-8227(00)00143-1

    authors: Uto H,Matsuoka H,Murata M,Okamoto T,Miyata Y,Hori T,Ido A,Hirono S,Hayashi K,Tsubouchi H

    更新日期:2000-08-01 00:00:00

  • The levels of plasma growth arrest-specific protein 6 is associated with insulin sensitivity and inflammation in women.

    abstract:AIMS:Vitamin K-dependent growth arrest-specific protein 6 (Gas6) and its receptors of the TAM (TYRO-3/Axl/Mer) family are ubiquitously expressed in immune, cardiovascular, and reproductive systems. They play pivotal roles of regulating tissue homeostasis via anti-inflammatory effects. Recent studies show that the Gas6/...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2013.12.057

    authors: Kuo FC,Hung YJ,Shieh YS,Hsieh CH,Hsiao FC,Lee CH

    更新日期:2014-02-01 00:00:00

  • Prevalence of resistant hypertension and associated factors in Japanese subjects with type 2 diabetes.

    abstract:OBJECTIVE:The prevalence of treatment resistant hypertension (RH) depends on methods used for blood pressure (BP) measurements, goals of BP, and therapeutic efforts in terms of medication and adherence. We focused on diabetic subjects and explored the prevalence of RH in primary care practice. METHODS:In 1737 subjects...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2015.08.007

    authors: Yokoyama H,Araki S,Watanabe S,Honjo J,Okizaki S,Yamada D,Shudo R,Shimizu H,Sone H,Haneda M

    更新日期:2015-10-01 00:00:00

  • The burden of diabetes and impaired glucose tolerance in India using the WHO 1999 criteria: prevalence of diabetes in India study (PODIS).

    abstract::This random multistage cross-sectional population survey was undertaken to determine the prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT) in subjects aged 25 years and above in India. The study was carried out in 77 centers (40 urban and 37 rural). 18363 (9008 males and 9355 females) subjects ...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2004.04.008

    authors: Sadikot SM,Nigam A,Das S,Bajaj S,Zargar AH,Prasannakumar KM,Sosale A,Munichoodappa C,Seshiah V,Singh SK,Jamal A,Sai K,Sadasivrao Y,Murthy SS,Hazra DK,Jain S,Mukherjee S,Bandyopadhay S,Sinha NK,Mishra R,Dora M,Je

    更新日期:2004-12-01 00:00:00

  • Challenges associated with treating children with diabetes in Saudi Arabia.

    abstract:BACKGROUND:Type 1 Diabetes Mellitus (T1DM) patients among the children have been increasing rapidly in the recent years in Saudi Arabia, as a result there is a need for extensive research in this area. Various suggestions were kept forward including m-health technologies, telemedicine etc. However, very little research...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2016.08.015

    authors: Alotaibi M,Alibrahim L,Alharbi N

    更新日期:2016-10-01 00:00:00

  • Serum level of the autophagy biomarker Beclin-1 in patients with diabetic kidney disease.

    abstract::Autophagy is a major cellular clearance mechanism that maintains cellular survival and homeostasis. Autophagy has a crucial role in the progression of diabetes and kidney diseases. AIMS:To investigate serum concentrations of Beclin-1, a key regulator of autophagy, in patients with diabetic kidney disease (DKD). METH...

    journal_title:Diabetes research and clinical practice

    pub_type: 杂志文章

    doi:10.1016/j.diabres.2018.06.022

    authors: Naguib M,Rashed LA

    更新日期:2018-09-01 00:00:00