Improving diabetes care: multi-component cardiovascular disease risk reduction strategies for people with diabetes in South Asia--the CARRS multi-center translation trial.

Abstract:

AIMS:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in people with diabetes in South Asia. The CARRS Translation Trial tests the effectiveness, cost-effectiveness, and sustainability of a clinic-based multi-component CVD risk reduction intervention among people with diabetes in India and Pakistan. METHODS:We randomly assigned 1146 adults with diabetes recruited from 10 urban clinic sites, to receive usual care by physicians or to receive an integrated multi-component CVD risk reduction intervention. The intervention involves electronic health record management, decision-support prompts to the healthcare team, and the support of a care coordinator to actively facilitate patient and provider adherence to evidence-based guidelines. The primary outcome is a composite of multiple CVD risk factor control (blood glucose and either blood pressure or cholesterol, or all three). Other outcomes include control of the individual CVD risk factors, process and patient-centered measures, cost-effectiveness, and acceptability/feasibility. CONCLUSION:The CARRS Translation Trial tests a low-cost diabetes care delivery model in urban South Asia to achieve comprehensive cardio-metabolic disease case-management of high-risk patients (clinicaltrials.gov number: NCT01212328).

authors

CARRS Trial Writing Group.,Shah S,Singh K,Ali MK,Mohan V,Kadir MM,Unnikrishnan AG,Sahay RK,Varthakavi P,Dharmalingam M,Viswanathan V,Masood Q,Bantwal G,Khadgawat R,Desai A,Sethi BK,Shivashankar R,Ajay VS,Reddy KS,Na

doi

10.1016/j.diabres.2012.09.023

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

285-94

issue

2

eissn

0168-8227

issn

1872-8227

pii

S0168-8227(12)00327-0

journal_volume

98

pub_type

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