Abstract:
:Since Sternberg et al. in 1985 first published preliminary results of polychemotherapy in patients with metastatic bladder cancer, it became apparent that transitional carcinoma of the bladder is highly responsive to chemotherapy. Response rates up to 70% with combination therapy regimens like methotrexate, vinblastine, doxorubicin or adriamycin and cisplatin promised that transitional carcinoma might be able to cure even in advanced stages. Chemotherapy has either been applied prior to the local treatment (such as radical cystectomy or radiotherapy) in a neo-adjuvant regimen, or after local therapy in an adjuvant regimen. Although a large number of studies have been published in the past 20 years, the role of the different chemotherapeutic approaches has not been clearly defined. Therefore, neither neo-adjuvant nor adjuvant chemotherapy can be recommended as 'gold standard' treatment for advanced bladder cancer.
journal_name
Curr Opin Uroljournal_title
Current opinion in urologyauthors
Schultz-Lampel D,Lampel Adoi
10.1097/00042307-199909000-00009subject
Has Abstractpub_date
1999-09-01 00:00:00pages
419-24issue
5eissn
0963-0643issn
1473-6586journal_volume
9pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:Prostate cancer is the most commonly diagnosed malignancy in men. Gray-scale ultrasound-guided systematic biopsy is the standard of care for prostate cancer detection in men with an elevated prostate-specific antigen or an abnormal digital rectal examination. Systematic biopsy may miss up to 35% of cl...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e328011b85c
更新日期:2007-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Radical cystectomy with pelvic lymph node dissection (PLND) is the preferred treatment for invasive bladder cancer. It not only results in the best disease-free term survival rates, but also provides the most accurate disease staging and most effective local symptom control. Recent investigations have...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32833c9194
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to analyze and discuss all recently published articles associated with neurogenic voiding discussion providing readers with the most updated knowledge and trigger for further research. RECENT FINDINGS:They include the proposal of a novel classification system for the pathophysiology ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000392
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:We review recent advancements in staging and imaging of penile cancer, including surveillance after therapy. RECENT FINDINGS:For cN0 patients, the sentinel lymph node biopsy is currently considered the preferred way for invasive staging. It has largely replaced other modalities such as staging inguin...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000447
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the reported effectiveness and safety of transobturator (TransOburator route, TOR) versus retropubic (retropubic tape) synthetic mid-urethral slings discussing the controversy existing on which of these procedures is best. RECENT FINDINGS:From August 2009 to January 2011 three meta-analyses...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3283476edb
更新日期:2011-07-01 00:00:00
abstract:PURPOSE OF REVIEW:In 2012, the United States Preventive Services Task Force (USPSTF) issued a grade 'D' recommendation against the use of routine prostate-specific antigen (PSA)-based screening for any men. This recommendation reflects critical misinterpretations of the available evidence base regarding benefits and ha...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000383
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Bladder cancer is a very frequent disease and represents the second most common genitourinary neoplasm. The most prevalent form of the disease, superficial bladder cancer, can recur in more than 70% of cases, despite correct management. Any way to improve our disease diagnostic and treatment policy is...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200309000-00001
更新日期:2003-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to provide a complete revision of two of the most widely used clinical guidelines in the management of lower urinary tract symptoms induced by benign prostatic hyperplasia and their importance and compliance among urologists. RECENT FINDINGS:Updates of the American Assoc...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32834d8e87
更新日期:2012-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Serenoa repens extract is a popular phytotherapeutic agent in men with lower urinary tract symptoms. Although the exact mechanism of action is unknown, the agent is generally well accepted for its easy availability and good tolerability. This paper reviews the evidence of its efficacy in comparison wi...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200501000-00011
更新日期:2005-01-01 00:00:00
abstract:PURPOSE OF REVIEW:This review focuses on recent advances in molecular embryology of the upper and lower urinary tract with an emphasis on clinical correlation in order to gain a better understanding for the mechanism of congenital anomalies. RECENT FINDINGS:Normal morphogenesis of the kidney, ureteral bud differentiat...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832c90ff
更新日期:2009-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Surgery is the mainstay for treating postprostatectomy stress urinary incontinence. Although the artificial urinary sphincter (AUS) remains a popular treatment option, a decade worth of innovations have expanded the role of male sling surgery. RECENT FINDINGS:AUS surgery has an approximately 80-85% s...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e328339b795
更新日期:2010-07-01 00:00:00
abstract::The proliferation of prostatic tissue as a result of ageing typically leads to prostatic enlargement, which often causes obstruction of urine outflow from the bladder, clinically lower urinary tract symptoms, detrusor instability, incomplete bladder emptying, urinary infection, and finally acute urinary retention. The...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200201000-00006
更新日期:2002-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Total adrenalectomy has been the standard treatment for small adrenal masses for years. In recent times, however, partial adrenalectomy and cortex-preserving strategies are gaining more importance. Therefore, we evaluated indications, techniques and outcome of partial adrenalectomy. RECENT FINDINGS:W...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000147
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Prostate cancer screening has shifted the diagnosis of prostate cancer to lower grade, organ confined disease. Radical prostatectomy or radiation therapy has been shown to be overtreatment in 30% of patients. In this review, we will discuss targeted focal therapy (TFT) using the modalities of cryother...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832a2c4a
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to summarize recent developments in the array of devices which are commonly used by urologists in the surgical management of kidney stones. To accomplish this goal, an extensive review of recent endourology literature, conference abstracts, and publicly available document...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000710
更新日期:2020-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Management of men with benign prostatic hyperplasia should reduce the lifetime risk of acute urinary retention and the need for benign prostatic hyperplasia-related surgery. A number of recent studies demonstrate that 5alpha-reductase inhibitors are unique in providing a long-term combination of impro...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200401000-00010
更新日期:2004-01-01 00:00:00
abstract:PURPOSE OF REVIEW:In recent years, robotic partial nephrectomy has emerged as a technique for treatment of small renal masses alongside laparoscopic and open partial nephrectomy. Since this technique is still in a phase of adoption, many technical improvements, alterations and early experiences are published. We aim to...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32833c7af0
更新日期:2010-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Robotic assisted simple prostatectomy (RASP) represents a minimally invasive evolution of traditional open simple prostatectomy for the surgical treatment of severe lower urinary tract symptoms (LUTS) because of benign prostatic enlargement (BPE). Aim of the present review is to summarize the most rec...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000499
更新日期:2018-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Cytoreductive nephrectomy has an established role in management of metastatic renal cell carcinoma when performed in properly selected patients prior to administration of systemic cytokine therapy. Within the past several years, novel molecular targeted agents have not only revolutionized management o...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32830a4f21
更新日期:2008-09-01 00:00:00
abstract:PURPOSE OF REVIEW:The newly discovered female urinary microbiota has the potential to deepen our understanding of urinary tract health and disease, including common lower urinary tract conditions such as urinary incontinence and urinary tract infection. The spectrum of painful bladder disorders and other less common co...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000396
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Supine percutaneous nephrolithotomy (PCNL) has been described in 1988 and several modifications followed since. Despite claimed benefits, supine PCNL is still neglected by the majority of urologists. Lack of experience and the fear of complications are possible explanations for the resistance to supin...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000023
更新日期:2014-03-01 00:00:00
abstract:PURPOSE OF REVIEW:To perform a bicenter, retrospective study of perioperative outcomes of retroperitoneal versus transperitoneal robotic-assisted laparoscopic partial nephrectomy (RALPN) and assess costs using time-driven activity-based costing (TDABC). We identified 355 consecutive patients who underwent RALPN at Univ...
journal_title:Current opinion in urology
pub_type: 杂志文章,多中心研究
doi:10.1097/MOU.0000000000000483
更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF REVIEW:A dedicated operating room with fluoroscopic imaging capability and adequate data connectivity is important to the success of any endourology program. Proper understanding of the recent developments in technology in relation to operating room is necessary before planning an endourology operating room....
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32835d3133
更新日期:2013-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Postbiopsy infections (PBIs) are among the most common complications associated with transrectal ultrasound-guided prostate biopsy (TRUSPB). This article discusses the pathogenesis of TRUSPB-associated infectious complications and reviews the most recent findings on techniques to prevent PBIs. RECENT...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000507
更新日期:2018-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To summarize the current knowledge about smoking carcinogenesis in bladder cancer (BCa), individual susceptibility and impact of smoking on incidence and outcomes of nonmuscle invasive BCa (NMIBC) and muscle-invasive BCa (MIBC). To assess the impact of smoking cessation on oncological outcomes. RECEN...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000453
更新日期:2018-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Trimodal therapy (TMT) is considered the most effective bladder-sparing approach for muscle-invasive urothelial carcinoma of the bladder (MIBC) and an alternative to radical cystectomy. The purpose of this article was to review and summarize the current knowledge on the equivalence of TMT and radical ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000203
更新日期:2015-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Partial nephrectomy provides equivalent long-term oncologic and superior functional outcomes as radical nephrectomy for T1a renal masses. Herein, we review the various vascular clamping techniques employed during minimally invasive partial nephrectomy, describe the evolution of our partial nephrectomy...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000140
更新日期:2015-03-01 00:00:00
abstract::Data are reviewed relating to the safety and efficacy of minimally invasive transurethral microwave thermotherapy and medical management in patients with lower urinary tract symptoms of benign prostatic hyperplasia. Recent evidence is summarized indicating more pronounced long-term beneficial effects of microwave trea...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200101000-00001
更新日期:2001-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The present article reviews the history of mesh-related complications and regulations in SUI and POP repair settings, clinical outcomes associated with the use of biologic and synthetic mesh materials, and novel approaches using modified mesh materials. RECENT FINDINGS:Treatment of pelvic floor disor...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000645
更新日期:2019-07-01 00:00:00
abstract::The artificial urinary sphincter has been in use for more than 25 years as a treatment for urinary incontinence due to intrinsic sphincter deficiency. Recent clinical studies have increased our knowledge concerning its use in children and in adult patient populations. Particularly, more long-term data and data on the ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200005000-00006
更新日期:2000-05-01 00:00:00