Abstract:
PURPOSE OF REVIEW:To summarize the current knowledge about smoking carcinogenesis in bladder cancer (BCa), individual susceptibility and impact of smoking on incidence and outcomes of nonmuscle invasive BCa (NMIBC) and muscle-invasive BCa (MIBC). To assess the impact of smoking cessation on oncological outcomes. RECENT FINDINGS:Smoking pattern, intensity, and duration are responsible for an increased risk of developing BCa and for worse tumor features at presentation. Tobacco consumption is associated with a higher risk of recurrence in NMIBC and with an impaired intravesical therapy efficacy. To date, the impact of smoking on oncological outcomes after radical surgery remains unclear. SUMMARY:Smoking cessation decreases the risk of BCa and may also allow benefits on treatment outcomes. Nonetheless, the magnitude of the effect remains unclear and prospective series with the specific aim of weighing smoking cessation on outcomes are needed. Because even a 5-min counseling in the urology setting may be sufficient to significantly enhance smoking cessation rates, adequate knowledge of links between tobacco and BCa, from its molecular pathophysiology and its harms to benefits of cessation is paramount for urologists and for everyday clinical practice.
journal_name
Curr Opin Uroljournal_title
Current opinion in urologyauthors
Soria F,Marra G,Čapoun O,Soukup V,Gontero Pdoi
10.1097/MOU.0000000000000453subject
Has Abstractpub_date
2018-01-01 00:00:00pages
80-87issue
1eissn
0963-0643issn
1473-6586journal_volume
28pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:This review focuses on recent advances in molecular embryology of the upper and lower urinary tract with an emphasis on clinical correlation in order to gain a better understanding for the mechanism of congenital anomalies. RECENT FINDINGS:Normal morphogenesis of the kidney, ureteral bud differentiat...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832c90ff
更新日期:2009-07-01 00:00:00
abstract:PURPOSE OF REVIEW:As high-risk nonmuscle invasive bladder cancer (NMIBC) has a high propensity to recur and progress, the primary therapeutic goal in patients with high-risk NMIBC is the prevention or delay of disease recurrence and progression. RECENT FINDINGS:For improving transurethral resection quality, new optica...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e328356adff
更新日期:2012-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Prostate cancer is the most common solid organ cancer type among American men. Screening and imaging aim to detect early-stage disease that is biologically aggressive. The focus of this study is to review multiparametric MRI in the detection and risk stratification of prostate cancer. RECENT FINDINGS...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32835481c2
更新日期:2012-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Benign prostatic hyperplasia is the most common human neoplasm and it is the most frequent tumour requiring surgical treatment in men. Not surprisingly, interest centres on either understanding of prostatic growth during ageing or on various medical or interventional treatments. RECENT FINDINGS:Recen...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200301000-00003
更新日期:2003-01-01 00:00:00
abstract:PURPOSE OF REVIEW:We review recent advancements in staging and imaging of penile cancer, including surveillance after therapy. RECENT FINDINGS:For cN0 patients, the sentinel lymph node biopsy is currently considered the preferred way for invasive staging. It has largely replaced other modalities such as staging inguin...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000447
更新日期:2017-11-01 00:00:00
abstract:PURPOSE OF REVIEW:A public health emergency has been declared in response to rising opioid addiction and opioid-related deaths in the United States. As kidney stones have been identified as an important source of initial and repeated opioid exposures, this review seeks to describe the scope of the problem and report re...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000705
更新日期:2020-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Overall survival remains the benchmark in phase III settings of novel agents in castration-resistant metastatic prostate cancer. This review highlights many of the current potential early measures of response and clinical benefit that are worthy of future study and validation in this disease. RECENT ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3282fb7807
更新日期:2008-05-01 00:00:00
abstract:PURPOSE OF REVIEW:We outline a generic approach to using a nomogram to predict a continuous probability of failure in high-risk patients (rather than putting patients into groups), in order to identify patients whose risk exceeds a cutoff point. We discuss the goals of any staging system, what markers should be include...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/00042307-200303000-00005
更新日期:2003-03-01 00:00:00
abstract::The artificial urinary sphincter has been in use for more than 25 years as a treatment for urinary incontinence due to intrinsic sphincter deficiency. Recent clinical studies have increased our knowledge concerning its use in children and in adult patient populations. Particularly, more long-term data and data on the ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200005000-00006
更新日期:2000-05-01 00:00:00
abstract:PURPOSE OF REVIEW:State-of-the-art proteomics technologies are currently being assessed for utility in the study of prostatic malignancy. This review aims to provide background information on the current proteomics techniques employed in prostate cancer research, recent reports showing the potential application of prot...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/01.mou.0000165547.48922.12
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Prostate cancer screening has shifted the diagnosis of prostate cancer to lower grade, organ confined disease. Radical prostatectomy or radiation therapy has been shown to be overtreatment in 30% of patients. In this review, we will discuss targeted focal therapy (TFT) using the modalities of cryother...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832a2c4a
更新日期:2009-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The standard diagnosis of carcinoma in situ (CIS) of the bladder, based on white light cystoscopy and urine cytology, is limited because CIS can vary from normal-appearing mucosa to a lesion indistinguishable from an inflammatory process. Intravesical instillation of Bacillus Calmette-Guerin (BCG) rem...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000758
更新日期:2020-05-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to analyze and discuss all recently published articles associated with neurogenic voiding discussion providing readers with the most updated knowledge and trigger for further research. RECENT FINDINGS:They include the proposal of a novel classification system for the pathophysiology ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000392
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:We summarize the evidence on accurate target definition, precise imaging, and guiding systems that are a necessary ground to targeted focal therapy. RECENT FINDINGS:Accurate target detection is based on the ability of imaging to locate and characterize precisely the tumor burden and differentiation i...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/MOU.0000000000000560
更新日期:2019-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The newly discovered female urinary microbiota has the potential to deepen our understanding of urinary tract health and disease, including common lower urinary tract conditions such as urinary incontinence and urinary tract infection. The spectrum of painful bladder disorders and other less common co...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000396
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Adolescent varicocele is a common lesion which remains poorly understood. Recent research in pathophysiology and surgical management has shed new light on this increasingly diagnosed clinical entity. RECENT FINDINGS:Recent research demonstrates the potential importance of heat and oxidative stress pa...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3281ddb30c
更新日期:2007-07-01 00:00:00
abstract::The treatment and prognosis of rhabdomyosarcoma of the urogenital tract have changed dramatically over the past few decades. Until the 1970s radical cystectomy and pelvic exenteration were the only therapeutic options in rhabdomyosarcoma of the bladder/prostate and of the vagina/uterus. Since then, multiagent chemothe...
journal_title:Current opinion in urology
pub_type: 社论,评审
doi:10.1097/00042307-200111000-00001
更新日期:2001-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Cytoreductive nephrectomy has an established role in management of metastatic renal cell carcinoma when performed in properly selected patients prior to administration of systemic cytokine therapy. Within the past several years, novel molecular targeted agents have not only revolutionized management o...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32830a4f21
更新日期:2008-09-01 00:00:00
abstract::Pharmacotherapy for men experiencing erectile dysfunction has undergone dramatic advances over the past 5 years with the introduction of an effective oral agent. Sildenafil has increased the pool of couples seeking treatment for this important health issue as well as expanding the numbers of physicians treating it. Re...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200111000-00011
更新日期:2001-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Postbiopsy infections (PBIs) are among the most common complications associated with transrectal ultrasound-guided prostate biopsy (TRUSPB). This article discusses the pathogenesis of TRUSPB-associated infectious complications and reviews the most recent findings on techniques to prevent PBIs. RECENT...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000507
更新日期:2018-07-01 00:00:00
abstract:PURPOSE OF REVIEW:To review the scientific literature on clinical applications of spectroscopy within urologic oncology. Specifically, we address the role of spectroscopy as a novel intraoperative or intraprocedural modality for the management of urothelial carcinoma, renal cell carcinoma, and prostate adenocarcinoma. ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000281
更新日期:2016-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Trimodal therapy (TMT) is considered the most effective bladder-sparing approach for muscle-invasive urothelial carcinoma of the bladder (MIBC) and an alternative to radical cystectomy. The purpose of this article was to review and summarize the current knowledge on the equivalence of TMT and radical ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000203
更新日期:2015-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To describe and critically discuss the most recent evidence regarding stone management during the coronavirus disease 2019 (COVID-19) and post-COVID-19 era. RECENT FINDINGS:There is a need to plan for resuming the normal elective stone surgery in the post-COVID era, keeping a clear record of all surg...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/MOU.0000000000000857
更新日期:2021-03-01 00:00:00
abstract::As a result of the recent resurgence of interest in interstitial brachytherapy, extended follow-up studies of early experience in this field are now being reported. However, such outcomes must be evaluated within the context of recent comprehensive assessments of the age-specific natural history of conservatively mana...
journal_title:Current opinion in urology
pub_type: 社论,评审
doi:10.1097/00042307-199905000-00001
更新日期:1999-05-01 00:00:00
abstract:PURPOSE OF REVIEW:The aim of this article is to outline the initial development of histotripsy, a noninvasive image-guided focused ultrasound technology that mechanically homogenizes targeted tissues and to describe the results of preclinical translational research directed toward urologic applications. RECENT FINDING...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000001
更新日期:2014-01-01 00:00:00
abstract::After more than 100 years of innovation in hypospadias repair, new concepts regarding penile curvature, the urethral plate, and the means for urethroplasty are changing surgical practices. With the introduction of the tubularized incised plate technique it is possible to simplify decision-making algorithms in hypospad...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/00042307-199911000-00004
更新日期:1999-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Systemic treatment options for metastatic hormone-sensitive prostate cancer (mHSPC) have recently shifted from the traditional androgen deprivation therapy (ADT) monotherapy to multidrug approaches incorporating drugs initially approved for castration-resistant state and ADT. However, clinicians have ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000778
更新日期:2020-07-01 00:00:00
abstract::Advances in the diagnosis of early stage disease, and particularly the introduction of prostate-specific antigen (PSA) testing, have had a dramatic effect on the presentation and clinical management of prostate cancer during the past ten years. As a result, there have been significant epidemiological changes in countr...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200007000-00006
更新日期:2000-07-01 00:00:00
abstract:PURPOSE OF REVIEW:In contrast to the large amount of evidence reporting on the oncological significance of various clinicopathological and molecular parameters for survival in invasive bladder cancer, alterations of preoperative hematological and systemic inflammatory parameters have not been sufficiently addressed in ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32834966fa
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To give insight into the current literature on feasibility, safety and outcome of presurgical targeted molecular therapies (TMTs) before nephron-sparing surgery (NSS) in patients with renal cell carcinoma. RECENT FINDINGS:Presurgical TMTs have been proven to be effective and well tolerated for patien...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32836320a7
更新日期:2013-09-01 00:00:00