Abstract:
PURPOSE OF REVIEW:Prostate cancer screening has shifted the diagnosis of prostate cancer to lower grade, organ confined disease. Radical prostatectomy or radiation therapy has been shown to be overtreatment in 30% of patients. In this review, we will discuss targeted focal therapy (TFT) using the modalities of cryotherapy or high intensity focused ultrasound as an alternate treatment for low-risk prostate cancers. RECENT FINDINGS:TFT uses 3-D mapping biopsies to guide treatment so lesions of interest are ablated whereas sparing surrounding healthy tissues, avoiding the side-effects associated with more invasive treatments. In recent years, improvements in cryotherapy and HIFU have increased efficacy whereas decreasing complications. Prostate cancer control reported following TFT is promising. SUMMARY:With data demonstrating effective treatment in select patients, physicians can better inform their patients of the options available to eradicate their prostate cancer. TFT provides an alternative to active surveillance and more aggressive treatments for patients with low-risk tumors. As studies mature, more information regarding long-term survival and benefit will become more evident.
journal_name
Curr Opin Uroljournal_title
Current opinion in urologyauthors
Hou AH,Sullivan KF,Crawford EDdoi
10.1097/MOU.0b013e32832a2c4asubject
Has Abstractpub_date
2009-05-01 00:00:00pages
283-9issue
3eissn
0963-0643issn
1473-6586journal_volume
19pub_type
杂志文章,评审abstract:PURPOSE OF REVIEW:State-of-the-art proteomics technologies are currently being assessed for utility in the study of prostatic malignancy. This review aims to provide background information on the current proteomics techniques employed in prostate cancer research, recent reports showing the potential application of prot...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/01.mou.0000165547.48922.12
更新日期:2005-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Several novel treatment modalities have been introduced for patients across all renal cell carcinoma stages. Observation or a variety of minimally invasive approaches can be applied to small renal masses. Conversely, aggressive loco-regional resections may be performed for locally advanced disease. Cy...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3282a4a6b7
更新日期:2007-09-01 00:00:00
abstract::Advances in the diagnosis of early stage disease, and particularly the introduction of prostate-specific antigen (PSA) testing, have had a dramatic effect on the presentation and clinical management of prostate cancer during the past ten years. As a result, there have been significant epidemiological changes in countr...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200007000-00006
更新日期:2000-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The incidence of renal cell carcinoma and the detection of incidental small renal masses are rising. Urologists are faced with difficult management decisions on how to treat patients with small renal masses. Traditionally, the treatment of suspicious renal masses was radical nephrectomy. However, neph...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3283551f84
更新日期:2012-09-01 00:00:00
abstract::The indications for ureteroscopic lithotripsy have increased with endoscope miniaturization and powerful, precise endoscopic lithotrites like the holmium: yttrium-aluminum-garnet laser. Successful ureteropyeloscopic treatment with the currently available instrumentation and techniques is independent of the size, compo...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-199907000-00010
更新日期:1999-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Training in female urology in Europe so far has been a national focus of individual European countries. Because of reasons like differentiation in pathology, activities of other specialisms like gynaecology and reimbursement issues, the way in which extra training in female urology is organized varies...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832ae1a4
更新日期:2009-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Molecular imaging with PET/CT targeting the prostate-specific membrane antigen (PSMA) receptor is increasingly utilized in men with prostate cancer (PCa), with clinical indications now expanding beyond biochemical recurrence. PSMA PET/CT often detects sub-centimetre size pathologic nodes and low-volum...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000799
更新日期:2020-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review aims to analyze and discuss all recently published articles associated with neurogenic voiding discussion providing readers with the most updated knowledge and trigger for further research. RECENT FINDINGS:They include the proposal of a novel classification system for the pathophysiology ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000392
更新日期:2017-05-01 00:00:00
abstract:PURPOSE OF REVIEW:In contrast to the large amount of evidence reporting on the oncological significance of various clinicopathological and molecular parameters for survival in invasive bladder cancer, alterations of preoperative hematological and systemic inflammatory parameters have not been sufficiently addressed in ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32834966fa
更新日期:2011-09-01 00:00:00
abstract:PURPOSE OF REVIEW:To give an overview of current options for conservative treatment of patients failing intravesical bacillus Calmette-Guerin (BCG) and to discuss emerging approaches with potential future clinical applications. RECENT FINDINGS:Radical cystectomy is the standard-of-care for patients failing BCG therapy...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/MOU.0000000000000593
更新日期:2019-05-01 00:00:00
abstract:PURPOSE OF REVIEW:Monitoring and improving the quality of healthcare is an evolving process that involves patients, physicians, and healthcare purchasers. Growing interest is seen in addressing quality concerns with policy changes. Surgeon and hospital volumes for specific high-risk procedures have been shown to be pre...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/01.mou.0000240307.85829.7a
更新日期:2006-09-01 00:00:00
abstract:PURPOSE OF REVIEW:This review focuses on novel imaging techniques used for guiding urologic procedures that are likely to provide additional opportunities to physicians in the years to come. RECENT FINDINGS:In the past, most image-guided urologic procedures have utilized two-dimensional x-ray images. This review will ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3282f1c5d3
更新日期:2008-01-01 00:00:00
abstract:PURPOSE OF REVIEW:As high-risk nonmuscle invasive bladder cancer (NMIBC) has a high propensity to recur and progress, the primary therapeutic goal in patients with high-risk NMIBC is the prevention or delay of disease recurrence and progression. RECENT FINDINGS:For improving transurethral resection quality, new optica...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e328356adff
更新日期:2012-09-01 00:00:00
abstract:PURPOSE OF REVIEW:Ureteral stents are a mainstay of today's urological armamentarium. This review critically evaluates the recent literature and provides a concise summary of the use of stents in urology today. While stents are used in many reconstructive urologic procedures, this review focuses on the use of stents in...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200403000-00011
更新日期:2004-03-01 00:00:00
abstract::Techniques that are aimed at regeneration of human tissues and organs (tissue engineering) have recently entered into clinical practice. Tissue engineering is currently among the fastest growing areas in medicine, and involves the application of the principles of biology and engineering to the development of functiona...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200105000-00006
更新日期:2001-05-01 00:00:00
abstract::Although there has been a recent surge of interest in chronic prostatitis, which hopefully will translate into advances in our understanding of the distribution and determinants of this condition, at present there is a scarcity of published epidemiologic research on chronic prostatitis. However, from the currently ava...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/00042307-199801000-00007
更新日期:1998-01-01 00:00:00
abstract:PURPOSE OF REVIEW:The difficulties of defining and evaluating bladder outlet obstruction (BOO) in the female patient have been described for several years. This review aims to examine recent literature to summarize progress in the area. RECENT FINDINGS:Within the last 2 years, functional causes of female BOO have been...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000182
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:Adolescent varicocele is a common lesion which remains poorly understood. Recent research in pathophysiology and surgical management has shed new light on this increasingly diagnosed clinical entity. RECENT FINDINGS:Recent research demonstrates the potential importance of heat and oxidative stress pa...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e3281ddb30c
更新日期:2007-07-01 00:00:00
abstract:PURPOSE OF REVIEW:In this review, we highlight the use of clinical registries for quality improvement and research purposes in urology. We focus on national and regional clinical database registries, such as the National Surgical Quality Improvement Programme, the Cancer of the Prostate Strategic Urologic Research Ende...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000406
更新日期:2017-07-01 00:00:00
abstract:PURPOSE OF REVIEW:This review focuses on recent advances in molecular embryology of the upper and lower urinary tract with an emphasis on clinical correlation in order to gain a better understanding for the mechanism of congenital anomalies. RECENT FINDINGS:Normal morphogenesis of the kidney, ureteral bud differentiat...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e32832c90ff
更新日期:2009-07-01 00:00:00
abstract::The treatment and prognosis of rhabdomyosarcoma of the urogenital tract have changed dramatically over the past few decades. Until the 1970s radical cystectomy and pelvic exenteration were the only therapeutic options in rhabdomyosarcoma of the bladder/prostate and of the vagina/uterus. Since then, multiagent chemothe...
journal_title:Current opinion in urology
pub_type: 社论,评审
doi:10.1097/00042307-200111000-00001
更新日期:2001-11-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this study is to review and discuss recently published studies of therapeutic options in cases with the combination of severe sphincteric damage and recurrent stricture of the bladder neck or anastomosis in patients with postradical prostatectomy. RECENT FINDINGS:Recent focus has been ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000185
更新日期:2015-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The recent increase in research with regard to premature ejaculation has led to a significant number of new papers looking at the diagnosis, definition, aetiology and management of this condition. RECENT FINDINGS:The intravaginal ejaculatory latency time remains the primary measure of ejaculatory tim...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/01.mou.0000186844.40506.98
更新日期:2005-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Phosphodiesterase 5 (PDE-5) inhibitors are established as first-line therapy in erectile dysfunction. There is emerging evidence that they may have a role in treating patients with lower urinary tract symptoms (LUTS) from benign prostatic hypertrophy. RECENT FINDINGS:All three commonly used PDE-5 inh...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0b013e328316c357
更新日期:2009-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Systemic treatment options for metastatic hormone-sensitive prostate cancer (mHSPC) have recently shifted from the traditional androgen deprivation therapy (ADT) monotherapy to multidrug approaches incorporating drugs initially approved for castration-resistant state and ADT. However, clinicians have ...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000778
更新日期:2020-07-01 00:00:00
abstract:PURPOSE OF REVIEW:The purpose of this review is to identify possible reasons why prostate cancer suboptimally responds to immune therapies. RECENT FINDINGS:Interrogation of the intraprostatic milieu suggests that within the normal prostate, foci of tumor can be surrounded by inflammatory cells that may or may not repr...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000334
更新日期:2016-11-01 00:00:00
abstract:PURPOSE OF REVIEW:Partial nephrectomy provides equivalent long-term oncologic and superior functional outcomes as radical nephrectomy for T1a renal masses. Herein, we review the various vascular clamping techniques employed during minimally invasive partial nephrectomy, describe the evolution of our partial nephrectomy...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000140
更新日期:2015-03-01 00:00:00
abstract:PURPOSE OF REVIEW:Benign prostatic hyperplasia is the most common human neoplasm and it is the most frequent tumour requiring surgical treatment in men. Not surprisingly, interest centres on either understanding of prostatic growth during ageing or on various medical or interventional treatments. RECENT FINDINGS:Recen...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/00042307-200301000-00003
更新日期:2003-01-01 00:00:00
abstract:PURPOSE OF REVIEW:Immunotherapies for urological malignancies have made tremendous progress by targeting immune checkpoints and have been implemented in clinical practice nowadays. Though siginifcant number of patients does not respond to immunotherapy. Biomarkers could help to predict response to treatment, but are st...
journal_title:Current opinion in urology
pub_type: 杂志文章,评审
doi:10.1097/MOU.0000000000000465
更新日期:2018-01-01 00:00:00
abstract::This paper reviews the major publications over the past year regarding upper urinary tract reconstruction. Controversies in the diagnosis of ureteropelvic junction obstruction and in the surgical repair of the obstructed upper urinary tract are discussed. Special emphasis is placed on issues surrounding minimally inva...
journal_title:Current opinion in urology
pub_type: 杂志文章
doi:10.1097/00042307-199805000-00004
更新日期:1998-05-01 00:00:00