Abstract:
:Two novel norhumulene-type sesquiterpenes, named mikaniahumulene I (1) and II (2) were isolated along with nine known compounds, seven kaurenic acid-type diterpenes (3-9), a coumarin (10) and a flavone (11), from the aerial parts of Mikania hirsutissima DC (Compositae). The structures of new norhumulenes were determined by spectroscopic means. The cytotoxic activities of isolated compounds against leukemia cells (L 1210) were investigated; among the isolated compounds, 1, 5, 8, and 11 showed relatively strong cytotoxicity.
journal_name
Chem Pharm Bull (Tokyo)journal_title
Chemical & pharmaceutical bulletinauthors
Ohkoshi E,Makino M,Fujimoto Ydoi
10.1248/cpb.47.1436subject
Has Abstractpub_date
1999-10-01 00:00:00pages
1436-8issue
10eissn
0009-2363issn
1347-5223journal_volume
47pub_type
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journal_title:Chemical & pharmaceutical bulletin
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journal_title:Chemical & pharmaceutical bulletin
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journal_title:Chemical & pharmaceutical bulletin
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journal_title:Chemical & pharmaceutical bulletin
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journal_title:Chemical & pharmaceutical bulletin
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