Case series: clonidine has no systematic effects on PR or QTc intervals in children.

Abstract:

:This study retrospectively examined the effects of clonidine, both alone and combined with psychostimulants, on the electrocardiograms (ECGs) of children and adolescents. Two pediatric cardiologists, blinded to treatment condition, examined pre- and posttreatment ECGs in 42 subjects treated with clonidine for attention-deficit/hyperactivity or tic disorder. While ECG variability was found, it did not appear to be related to any systematic effect of clonidine, either alone or in combination with psychostimulants. These data do not rule out the possibility of rare idiosyncratic reactions to clonidine with or without psychostimulants, though none occurred in this sample.

authors

Kofoed L,Tadepalli G,Oesterheld JR,Awadallah S,Shapiro R

doi

10.1097/00004583-199909000-00026

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

1193-6

issue

9

eissn

0890-8567

issn

1527-5418

pii

S0890-8567(09)63220-2

journal_volume

38

pub_type

杂志文章
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  • Editorial: Making Use of What We Know: Medical Decision-Making and Antipsychotics.

    abstract::Minimizing the duration of untreated psychosis and providing comprehensive early intervention including the use of antipsychotics reflects best practice in the treatment of first-episode psychosis (FEP).1 The adverse effects of second-generation antipsychotics (SGAs) are well known, namely, weight gain, hyperglycemia,...

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  • Hypothalamic-pituitary-adrenal axis and autonomic nervous system activity in disruptive children and matched controls.

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    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

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    journal_title:Journal of the American Academy of Child and Adolescent Psychiatry

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