当前位置： SCI文献检索 > AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY期刊下所有文献 > Induction of antenatal periventricular leukomalacia by hemorrhagic hypotension in the chronically instrumented fetal sheep.

Induction of antenatal periventricular leukomalacia by hemorrhagic hypotension in the chronically instrumented fetal sheep.

Abstract：

OBJECTIVES:Our purpose was to determine whether systemic hypotension induced by rapid withdrawal of fetal blood would induce periventricular leukomalacia in the brain of premature fetal sheep. STUDY DESIGN:At 113 days' gestation, systemic hypotension (mean blood pressure <30 mm Hg) was induced by withdrawing approximately 35% of the fetoplacental blood volume in the hemorrhage group (n = 6), whereas in the control group (n = 4) isovolemic exchange transfusion was carried out. Six days after the insult, fetal brains were removed and processed for histologic analysis. RESULTS:Five of the 6 fetuses in the hemorrhage group exhibited periventricular white-matter lesions, consisting of nodular coagulation necrosis or diffuse axonal swellings or both. No abnormal findings other than these lesions were detected in the fetal brains in either experimental group. CONCLUSION:Hemorrhagic hypotension antenatally induced brain lesions similar to those of periventricular leukomalacia, suggesting that it is an essential element in the pathogenesis of periventricular leukomalacia in premature fetuses.

journal_name

Am J Obstet Gynecol

journal_title

American journal of obstetrics and gynecology

authors

Matsuda T,Okuyama K,Cho K,Hoshi N,Matsumoto Y,Kobayashi Y,Fujimoto S

doi

10.1016/s0002-9378(99)70519-3

subject

Has Abstract

pub_date

1999-09-01 00:00:00

pages

725-30

issue

3

eissn

0002-9378

issn

1097-6868

pii

S0002937899705193

journal_volume

181

pub_type

杂志文章

相关文献

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY文献大全
  • The pattern of infertility diagnoses in women of advanced reproductive age.

    abstract：OBJECTIVE:Our intention was to determine whether there is a unique pattern of infertility diagnoses in older infertile couples. STUDY DESIGN:The design of this study was a retrospective chart review study. It was performed in a tertiary referral reproductive medicine unit. There were 2 groups of patients-couples: grou...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(99)70331-5

    authors： Miller JH,Weinberg RK,Canino NL,Klein NA,Soules MR

    更新日期：1999-10-01 00:00:00

  • Benefits, risks, costs, and patient satisfaction associated with insulin pump therapy for the pregnancy complicated by type 1 diabetes mellitus.

    abstract：OBJECTIVE:Glycemic control, perinatal outcome, and health care costs were evaluated among women with type 1 diabetes mellitus who began insulin pump therapy during pregnancy (group 1, n = 24), were treated with multiple insulin injections (group 2, n = 24), or were already using an insulin pump before pregnancy (group ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2000.106182

    authors： Gabbe SG,Holing E,Temple P,Brown ZA

    更新日期：2000-06-01 00:00:00

  • The transition from latent to active labor and adverse obstetrical outcomes.

    abstract：BACKGROUND:Recommendations on preventing primary cesarean delivery removed the previously defined time limits for latent labor (defined as ending at 6 cm) and urged clinicians to avoid cesarean delivery for labor abnormalities in the latent phase. However, relatively little is known about the implications of labor curv...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2019.05.041

    authors： Rosenbloom JI,Woolfolk CL,Wan L,Stout MJ,Tuuli MG,Macones GA,Cahill AG

    更新日期：2019-11-01 00:00:00

  • Best practices in surgical abortion.

    abstract：:Surgical abortion in the first trimester comprises the majority of voluntary pregnancy interruptions performed in the United States. The majority of these procedures are done in outpatient settings with the patient under local anesthesia. Appropriate volume of and deep injection of local anesthetic can reduce pain ass...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1067/s0002-9378(03)00107-8

    authors： Keder LM

    更新日期：2003-08-01 00:00:00

  • The safety of calcium channel blockers in human pregnancy: a prospective, multicenter cohort study.

    abstract：OBJECTIVE:Our purpose was to examine the potential teratogenicity of calcium channel blockers. STUDY DESIGN:Six teratogen information services prospectively collected and followed up 78 women with first-trimester exposure to calcium channel blockers. Pregnancy outcome was compared (by paired t text of chi2 analysis) w...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 临床试验,杂志文章,多中心研究

    doi：10.1016/s0002-9378(96)70307-1

    authors： Magee LA,Schick B,Donnenfeld AE,Sage SR,Conover B,Cook L,McElhatton PR,Schmidt MA,Koren G

    更新日期：1996-03-01 00:00:00

  • Comparison of suture materials for subcuticular skin closure at cesarean delivery.

    abstract：BACKGROUND:Subcuticular skin closure with suture after cesarean has been shown to result in lower rates of wound complications than with staple closure. However, the optimal choice of suture material for subcuticular skin closure is unclear. Vicryl (a braided multifilament synthetic suture; Ethicon, Somerville, NJ) and...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ajog.2016.05.012

    authors： Tuuli MG,Stout MJ,Martin S,Rampersad RM,Cahill AG,Macones GA

    更新日期：2016-10-01 00:00:00

  • Prevalence, trends, and outcomes of chronic hypertension: a nationwide sample of delivery admissions.

    abstract：OBJECTIVE:We sought to define the prevalence, trends, and outcomes of primary and secondary chronic hypertension in a population-based sample of deliveries. STUDY DESIGN:An estimated 56,494,634 deliveries were identified from the 1995 through 2008 Nationwide Inpatient Sample. The association of primary and secondary c...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2011.10.878

    authors： Bateman BT,Bansil P,Hernandez-Diaz S,Mhyre JM,Callaghan WM,Kuklina EV

    更新日期：2012-02-01 00:00:00

  • Doppler flow velocimetry of the splenic artery in the human fetus: is it a marker of chronic hypoxia?

    abstract：OBJECTIVE:The aim of this investigation was to describe splenic artery flow velocity waveforms in the appropriate- and small-for-gestational-age human fetus. STUDY DESIGN:Splenic artery flow velocity waveforms were prospectively obtained from 95 appropriate- and 15 small-for-gestational-age fetuses with pulsed Doppler...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(95)90005-5

    authors： Abuhamad AZ,Mari G,Bogdan D,Evans AT 3rd

    更新日期：1995-03-01 00:00:00

  • Defecation in utero: a physiologic fetal function.

    abstract：OBJECTIVE:The objective of this study was to investigate the occurrence of in utero defecation as a normal function in the human fetus. STUDY DESIGN:The anuses of 240 fetuses were studied sonographically between weeks 15 and 41 of gestation. Fetal defecation was defined as the expulsion of rectal contents through the ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2003.107

    authors： Ramón y Cajal CL,Martínez RO

    更新日期：2003-01-01 00:00:00

  • Acute gastric ulcer perforation in a 35 weeks' nulliparous patient with gastric banding.

    abstract：:We present a case of a primiparous patient at 35 weeks' gestation who had had laparoscopic gastric banding, and who presented to labor and delivery with protracted vomiting followed by an acute abdomen and fetal distress. An emergency surgery revealed acute gastric ulcer perforation. This complication, although rare, ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2004.03.036

    authors： Erez O,Maymon E,Mazor M

    更新日期：2004-11-01 00:00:00

  • Prostaglandin F2 alpha output by amnion-chorion-decidua: relationship with labor and prostaglandin E2 concentration at the amniotic surface.

    abstract：OBJECTIVE:Our purpose was to evaluate prostaglandin F2 alpha output at fetal membrane surfaces relative to labor and to assess amniotic prostaglandin E2 concentration changes on prostaglandin F2 alpha output. STUDY DESIGN:Intact and separated fetal membranes from 10 elective cesarean sections and nine vaginal deliveri...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(95)90190-6

    authors： Kredentser JV,Embree JE,McCoshen JA

    更新日期：1995-07-01 00:00:00

  • Iatrogenic prematurity due to elective termination of the uncomplicated pregnancy: a major perinatal health care problem.

    abstract：:In a series of 1,000 newborn infants referred to a regional neonatal center, 32 iatrogenically preterm infants were identified. All had been delivered following elective termination of uncomplicated, apparently term pregnancies, without prior documentation of fetal lung maturity or ultrasonic determination of fetal bi...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(78)90717-2

    authors： Flaksman RJ,Vollman JH,Benfield DG

    更新日期：1978-12-15 00:00:00

  • Pitfalls in assessing chorioamnionicity: novel observations and literature review.

    abstract：:Accurate diagnosis of chorioamnionicity in multiple pregnancies is the key to appropriate clinical management of multiple gestation. Although prenatal ultrasound assessment of chorioamnionicity is well established and highly accurate if performed in early pregnancy, exceptions and artifacts arise from anatomic variati...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ajog.2018.02.010

    authors： Lu J,Cheng YKY,Ting YH,Law KM,Leung TY

    更新日期：2018-09-01 00:00:00

  • Physical examination techniques for the assessment of pelvic floor myofascial pain: a systematic review.

    abstract：BACKGROUND:Myofascial pain is characterized by the presence of trigger points, tenderness to palpation, and local or referred pain, and commonly involves the pelvic floor muscles in men and women. Pelvic floor myofascial pain in the absence of local or referred pain has also been observed in patients with lower urinary...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2018.06.014

    authors： Meister MR,Shivakumar N,Sutcliffe S,Spitznagle T,Lowder JL

    更新日期：2018-11-01 00:00:00

  • Sex differences in lung and adrenal neurosympathetic development in rabbits.

    abstract：:To assess the possible mechanism for the increased incidence and severity of the respiratory distress syndrome (RDS) in male versus female infants, we studied neurosympathetic development in the lung and adrenal glands in male and female fetal and newborn rabbits. Tissue levels of catecholamines, norepinephrine (NE), ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(16)32593-5

    authors： Padbury JF,Hobel CJ,Lam RW,Fisher DA

    更新日期：1981-09-15 00:00:00

  • Microarray technology in obstetrics and gynecology: a guide for clinicians.

    abstract：:Microarrays can be constructed with dozens to millions of probes on their surface to allow high-throughput analyses of many biologic processes to be performed simultaneously on the same sample. Microarrays are now widely used for gene expression analysis, deoxyribonucleic acid resequencing, single-nucleotide polymorph...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ajog.2005.12.014

    authors： Ward K

    更新日期：2006-08-01 00:00:00

  • Magnesium sulfate induces translocation of protein kinase C isoenzymes alpha and delta in myometrial cells from pregnant women.

    abstract：OBJECTIVES:The purpose of this study was to determine the effect of magnesium sulfate on protein kinase C (PKC) translocation in myometrial cells from pregnant women. STUDY DESIGN:Myometrium was obtained at the time of cesarean delivery from women at term before labor. Cultured myometrial cells were treated with magne...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2003.09.009

    authors： Bermeo ME,Fomin VP,Ventolini G,Gibbs SG,McKenna DS,Hurd WW

    更新日期：2004-02-01 00:00:00

  • Platelet size and glycoprotein Ib and IIIa expression in normal fetal and maternal blood.

    abstract：OBJECTIVE:Our purpose was to study platelet size and surface glycoprotein expression in normal fetal and maternal blood throughout pregnancy. STUDY DESIGN:A cross-sectional study was performed at the Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London. Fetal and materna...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(94)90099-x

    authors： Meher-Homji NJ,Montemagno R,Thilaganathan B,Nicolaides KH

    更新日期：1994-09-01 00:00:00

  • Awareness and concern about ovarian cancer among women at risk because of a family history of breast or ovarian cancer.

    abstract：:Research on women at risk for breast cancer because of family history suggests that a substantial proportion need education and counseling to assist them in their efforts to understand their risk of breast cancer and that some do not get appropriate breast cancer screening. Although women at high genetic risk for brea...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/s0002-9378(03)01078-0

    authors： Andersen MR,Bowen D,Yasui Y,McTiernan A

    更新日期：2003-10-01 00:00:00

  • Inner thigh taping vs traction for cervical ripening with a Foley catheter: a randomized controlled trial.

    abstract：OBJECTIVE:To assess the effectiveness of inner thigh "Taping" compared with "Traction" using a weighted bag when an intracervical Foley catheter is used for cervical ripening. STUDY DESIGN:We performed a randomized controlled trial at a tertiary hospital on women with a singleton pregnancy in cephalic presentation adm...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ajog.2013.05.028

    authors： Gibson KS,Mercer BM,Louis JM

    更新日期：2013-09-01 00:00:00

  • The preterm prediction study: cervical lactoferrin concentration, other markers of lower genital tract infection, and preterm birth. National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network.

    abstract：OBJECTIVE:This study was undertaken to determine the relationship among cervical lactoferrin concentration, other cervical markers potentially related to infection, and spontaneous preterm birth. STUDY DESIGN:Cervical lactoferrin concentrations obtained at 22 to 24 weeks' gestation among 121 women who had a spontaneou...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2000.104211

    authors： Goldenberg RL,Andrews WW,Guerrant RL,Newman M,Mercer B,Iams J,Meis P,Moawad A,Das A,VanDorsten JP,Caritis SN,Thurnau G,Bottoms S,Miodovnik M,McNellis D,Roberts JM

    更新日期：2000-03-01 00:00:00

  • No evidence for lipid peroxidation in severe preeclampsia.

    abstract：OBJECTIVE:This study was undertaken to address the role of oxidative stress in preeclampsia. STUDY DESIGN:We measured urinary 8,12-iso-iPF(2alpha)-VI, a chemically stable, free-radical catalyzed product, in a case control study of severe preeclampsia nested within the trial of Calcium for Preeclampsia Prevention. Case...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2001.116754

    authors： Regan CL,Levine RJ,Baird DD,Ewell MG,Martz KL,Sibai BM,Rokach J,Lawson JA,Fitzgerald GA

    更新日期：2001-09-01 00:00:00

  • Further analysis of contraceptive failure of the ovulation method.

    abstract：:Reanalysis of data on the ovulation method of natural family planning collected by the World Health Organization yields the following conclusions. The method is effective during perfect (correct and consistent) use, with a first-year probability of failure of 3.4%. However, it is extremely unforgiving of imperfect use...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(11)90581-x

    authors： Trussell J,Grummer-Strawn L

    更新日期：1991-12-01 00:00:00

  • Peroxide induces vasoconstriction in the human placenta by stimulating thromboxane.

    abstract：OBJECTIVE:Placental lipid peroxides and thromboxane are abnormally increased in preeclampsia. Thromboxane is a potent vasoconstrictor of the placental vasculature. Peroxides stimulate cyclooxygenase (prostaglandin H synthase), and thereby could increase thromboxane, to cause vasoconstriction in the placenta. This study...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(93)90044-j

    authors： Walsh SW,Wang Y,Jesse R

    更新日期：1993-10-01 00:00:00

  • Estrogenic activity of RU 486 (mifepristone) in rat uterus and cultured uterine myocytes.

    abstract：OBJECTIVE:Our purpose was to determine whether RU 486 (mifepristone) has direct estrogenic activity in uterine myocytes. STUDY DESIGN:Ovariectomized adult rats were treated with RU 486, and its effect on uterine oxytocin receptor concentration, as a marker of estrogenic activity, was measured. Results were compared wi...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(95)90181-7

    authors： Dibbs KI,Sadovsky Y,Li XJ,Koide SS,Adler S,Fuchs AR

    更新日期：1995-07-01 00:00:00

  • Fetal evaluation by percutaneous blood sampling.

    abstract：:Percutaneous umbilical blood sampling (cordocentesis) provides direct access to the fetal circulation in the second and third trimesters of pregnancy. Seventeen patients underwent this procedure between December 1985 and December 1986 for evaluation of a variety of clinical situations, including nonlethal fetal abnorm...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(88)90795-8

    authors： Hogge WA,Thiagarajah S,Brenbridge AN,Harbert GM

    更新日期：1988-01-01 00:00:00

  • Circulating gonadotropins, estrogens, and androgens in polycystic ovarian disease.

    abstract：:Serum gonadotropin, estrogen, and androgen levels were measured in samples obtained from 19 patients with polycystic ovarian disease (PCO) and from 10 normal women on day 2 to 4 of their menstrual cycles. In patients with PCO, the mean (plus or minus S.E.) concentration was significantly higher (P smaller than 0.001) ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/0002-9378(75)90081-2

    authors： DeVane GW,Czekala NM,Judd HL,Yen SS

    更新日期：1975-02-15 00:00:00

  • The effect of peritoneal fluid from patients with endometriosis on human sperm function in vitro.

    abstract：OBJECTIVE:Our purpose was to evaluate the effect of peritoneal fluid from women with endometriosis on sperm motility and function in an in vitro model. STUDY DESIGN:Peritoneal fluid was collected at laparoscopy from patients with and without endometriosis. Human donor sperm was diluted with this fluid, and its effect ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/s0002-9378(96)70210-7

    authors： Aeby TC,Huang T,Nakayama RT

    更新日期：1996-06-01 00:00:00

  • Metabolomic analysis for first-trimester trisomy 18 detection.

    abstract：OBJECTIVE:The purpose of this study was to determine whether nuclear magnetic resonance-based metabolomic markers in first-trimester maternal serum can detect fetuses with trisomy 18. STUDY DESIGN:This was a study of pregnancies between 11 weeks and 13 weeks 6 days' gestation. We analyzed 30 cases of trisomy 18 and a ...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1016/j.ajog.2013.03.028

    authors： Bahado-Singh RO,Akolekar R,Chelliah A,Mandal R,Dong E,Kruger M,Wishart DS,Nicolaides K

    更新日期：2013-07-01 00:00:00

  • Treatment of uterine fibroid tumors in a nude mouse model using high-intensity focused ultrasound.

    abstract：OBJECTIVE:The purpose of this study was to investigate the potential efficacy of high-intensity focused ultrasound for the treatment of uterine fibroid tumors in a nude mouse model. STUDY DESIGN:A total of 60 female athymic nude mice were inoculated subcutaneously with 3 to 5 x 10(6) ELT-3 cells, a uterine fibroid tum...

    journal_title：American journal of obstetrics and gynecology

    pub_type： 杂志文章

    doi：10.1067/mob.2000.105347

    authors： Vaezy S,Fujimoto VY,Walker C,Martin RW,Chi EY,Crum LA

    更新日期：2000-07-01 00:00:00