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The Marks Asthma Quality of Life Questionnaire: further validation and examination of responsiveness to change.

Abstract：

:We performed analyses to examine the structure, validity, and responsiveness to change of the Marks Asthma Quality of Life Questionnaire (AQLQ), originally validated in Australia in a self-administered format, among 539 U.S. subjects with asthma. Subjects were interviewed twice by telephone over an 18-month period. Based on factor analyses, the subscale structure of the AQLQ was modified slightly to eliminate item overlap among subscale scores. Cross-sectionally, total AQLQ scores were significantly correlated in expected directions with baseline asthma severity scores (r = 0.58), SF-36 physical (r = -0.66) and mental (r = -0.40) health status scores, and pulmonary function (FEV1% predicted, r = -0.14). Longitudinally, changes in AQLQ total and subscale scores were significantly (P<0.01) associated with changes in asthma severity and both physical and mental status. The AQLQ, administered by telephone, appears to be useful for assessing changes in the impact of adult asthma.

journal_name

J Clin Epidemiol

journal_title

Journal of clinical epidemiology

authors

Katz PP,Eisner MD,Henke J,Shiboski S,Yelin EH,Blanc PD

doi

10.1016/s0895-4356(99)00026-8

subject

Has Abstract

pub_date

1999-07-01 00:00:00

pages

667-75

issue

7

eissn

0895-4356

issn

1878-5921

pii

S0895-4356(99)00026-8

journal_volume

52

pub_type

杂志文章

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