当前位置： SCI文献检索 > JOURNAL OF CLINICAL EPIDEMIOLOGY期刊下所有文献 > Reporting of trials presented in conference abstracts needs to be improved.

Reporting of trials presented in conference abstracts needs to be improved.

Abstract：

OBJECTIVES:To assess how trial information reported in conference abstracts differs to their subsequent full publication. METHODS:Randomized trials reported at the American Society of Clinical Oncology conference (1992) were identified. CENTRAL and PubMed (December 2002) were searched to identify corresponding full publications. A checklist (based on CONSORT) was used to compare abstracts for 37 trials with their full publication. RESULTS:Some aspects were well reported. Ninety-five percent of study objectives, 92% of participant eligibility, 100% of trial interventions, and 84% of primary outcomes were the same in both abstract and full publication. Other areas were more discrepant. Forty-six percent reported the same number of participants randomized in the abstract and full publication; only 22% reported the same number analyzed (median number analyzed per trial was 96 for abstracts and 117 for full publications). Eighty-two percent of trials were closed to follow-up in the full publication compared to 19% of abstracts. Lack of information was a major problem in assessing trial quality: no abstracts reported on allocation concealment, 16% reported on blinding and 14% reported intention to treat analysis. These figures were 49, 19, and 46%, respectively, for full publications. CONCLUSION:The information given for trials in conference proceedings can be unstable, especially for trials presenting early or preliminary results, and needs to be improved.

journal_name

J Clin Epidemiol

journal_title

Journal of clinical epidemiology

authors

Hopewell S,Clarke M,Askie L

doi

10.1016/j.jclinepi.2005.09.016

subject

Has Abstract

pub_date

2006-07-01 00:00:00

pages

681-4

issue

7

eissn

0895-4356

issn

1878-5921

pii

S0895-4356(06)00014-X

journal_volume

59

pub_type

杂志文章

相关文献

JOURNAL OF CLINICAL EPIDEMIOLOGY文献大全
  • Simulated computerized adaptive test for patients with shoulder impairments was efficient and produced valid measures of function.

    abstract：BACKGROUND AND OBJECTIVE:To test unidimensionality and local independence of a set of shoulder functional status (SFS) items, develop a computerized adaptive test (CAT) of the items using a rating scale item response theory model (RSM), and compare discriminant validity of measures generated using all items (theta(IRT)...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2005.08.006

    authors： Hart DL,Cook KF,Mioduski JE,Teal CR,Crane PK

    更新日期：2006-03-01 00:00:00

  • Using the outcome for imputation of missing predictor values was preferred.

    abstract：BACKGROUND AND OBJECTIVE:Epidemiologic studies commonly estimate associations between predictors (risk factors) and outcome. Most software automatically exclude subjects with missing values. This commonly causes bias because missing values seldom occur completely at random (MCAR) but rather selectively based on other (...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2006.01.009

    authors： Moons KG,Donders RA,Stijnen T,Harrell FE Jr

    更新日期：2006-10-01 00:00:00

  • Plasma fibrinogen and coronary risk factors: the Scottish Heart Health Study.

    abstract：:Plasma fibrinogen was measured in a sample of 8824 men and women aged 40-59 years participating in the Scottish Heart Health Study, and related to cardiovascular risk factors. Women had higher fibrinogen levels than men. In both sexes, multivariate analysis showed that fibrinogen was positively associated with age, sm...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(90)90075-z

    authors： Lee AJ,Smith WC,Lowe GD,Tunstall-Pedoe H

    更新日期：1990-01-01 00:00:00

  • Simultaneous interval estimates of the odds ratio in studies with two or more comparisons.

    abstract：:More than one odds ratio estimate will often arise from a single epidemiologic study. Examples of designs where this may occur include those where there is more than one case or control group, and investigations of several risk factors as part of the same study. Various methods for presenting multiple interval estimat...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(89)90132-7

    authors： Holford TR,Walter SD,Dunnett CW

    更新日期：1989-01-01 00:00:00

  • Do medical devices have enhanced placebo effects?

    abstract：:Although the placebo in a clinical trial is often considered simply a baseline against which to evaluate the efficacy of a clinical intervention, there is evidence that the magnitude of placebo effect may be a critical factor in determining the results of a trial. This article examines the question of whether devices ...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,评审

    doi：10.1016/s0895-4356(00)00206-7

    authors： Kaptchuk TJ,Goldman P,Stone DA,Stason WB

    更新日期：2000-08-01 00:00:00

  • The number needed to treat (NNT) can be adjusted for bias when the outcome is measured with error.

    abstract：BACKGROUND AND OBJECTIVE:We consider the number needed to treat (NNT) when the event of interest is defined by dichotomizing a continuous response at a threshold level. If the response is measured with error, the resulting NNT is biased. We consider methods to reduce this bias. METHODS:Bias adjustment was studied usin...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2004.01.021

    authors： Marschner IC,Emberson J,Irwig L,Walter SD

    更新日期：2004-12-01 00:00:00

  • Relationships of site of infarction and history of previous infarction with short- and long-term prognosis after acute myocardial infarction in Japan.

    abstract：:We studied the outcome in 308 patients with acute myocardial infarction (MI) admitted to the coronary care unit of Kobe General Hospital. Short-term outcome (within 28 days after MI) and long-term outcome (more than 28 days) were examined with survival curves to find any relationship with a history of previous MI and ...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(92)90186-q

    authors： Nishi N,Nakanishi N,Kuroda K,Koizumi K,Yoshikawa J,Tatara K

    更新日期：1992-01-01 00:00:00

  • Does physical activity lower blood pressure: a critical review of the clinical trials.

    abstract：:This review critically appraises 22 recent articles of trials of physical activity, as a means of reducing blood pressure. The quality of the literature remains poor and of the 13 controlled trials of habitual activity only one did not have a major design fault. Overall, blood pressure was reduced by physical activity...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,评审

    doi：10.1016/0895-4356(92)90093-3

    authors： Arroll B,Beaglehole R

    更新日期：1992-05-01 00:00:00

  • Factors relevant to preventing embolic stroke in patients with non-rheumatic atrial fibrillation.

    abstract：:Whether or not to treat patients with non-rheumatic atrial fibrillation with anticoagulants to prevent embolic stroke is a dilemma for physicians. If randomized trials, currently underway, demonstrate a beneficial effect, the dilemma will not be solved because not all of the relevant factors can be addressed by trials...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(91)90219-y

    authors： Flegel KM,Hutchinson TA,Groome PA,Tousignant P

    更新日期：1991-01-01 00:00:00

  • Systematic reviews do not comment on applicability for primary care.

    abstract：OBJECTIVES:How often authors comment on applicability for primary care in systematic reviews of clinical trials. STUDY DESIGN AND SETTING:We selected 4% of the Cochrane Database for Systematic Reviews (CDSRs; January 2008 to October 2013). We excluded reviews when primary care trials were not eligible. We extracted wh...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2015.06.003

    authors： Missiou A,Tatsioni A

    更新日期：2015-10-01 00:00:00

  • Clinical correlates of advanced retinopathy in type II diabetic patients: implications for screening. The CODIAB-INSERM-Zeneca Pharma Study Group.

    abstract：:The clinical correlates of advanced retinopathy were determined in a sample of 427 type II diabetic outpatients, aged 35 to 74 years, recruited in eight centers from all parts of France. The presence of retinopathy was assessed by fluorescein angiography with centralized interpretation. Advanced retinopathy (prolifera...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/0895-4356(95)00582-x

    authors： Delcourt C,Villatte-Cathelineau B,Vauzelle-Kervroedan F,Papoz L

    更新日期：1996-06-01 00:00:00

  • Test-retest of self-reported exposure to artificial tanning devices, self-tanning creams, and sun sensitivity showed consistency.

    abstract：OBJECTIVE:Exposure to ultraviolet radiation has consistently been linked to an increased risk of melanoma. Epidemiologic studies are susceptible to measurement error, which can distort the magnitude of observed effects. Although the reliability of self-report of many sun exposure factors has been previously described i...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2004.09.004

    authors： Beane Freeman LE,Dennis LK,Lynch CF,Lowe JB,Clarke WR

    更新日期：2005-04-01 00:00:00

  • Optimal survey design for community intervention evaluations: cohort or cross-sectional?

    abstract：:Community intervention evaluations that measure changes over time may conduct repeated cross-sectional surveys, follow a cohort of residents over time, or (often) use both designs. Each survey design has implications for precision and cost. To explore these issues, we assume that two waves of surveys are conducted, an...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(95)00055-0

    authors： Diehr P,Martin DC,Koepsell T,Cheadle A,Psaty BM,Wagner EH

    更新日期：1995-12-01 00:00:00

  • Half of Cochrane reviews were published more than 2 years after the protocol.

    abstract：OBJECTIVES:The objective of the study is to examine the time from publication of the protocol for a Cochrane review to publication of the Cochrane review for the entire Cochrane Database of Systematic Reviews (CDSR). STUDY DESIGN AND SETTINGS:Cochrane reviews from the CDSR published between 1995 and 2019 were assessed...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jclinepi.2020.05.011

    authors： Andersen MZ,Gülen S,Fonnes S,Andresen K,Rosenberg J

    更新日期：2020-08-01 00:00:00

  • Alcoholic beverages and breast cancer: some observations on published case-control studies.

    abstract：:We identified 38 case-control studies investigating possible associations between alcoholic beverage consumption and cancer of the female breast. Each study was characterized according to design features such as: control type (hospital or community based), risk factors controlled for, matching strategy, and statistica...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,评审

    doi：10.1016/0895-4356(94)90026-4

    authors： Roth HD,Levy PS,Shi L,Post E

    更新日期：1994-02-01 00:00:00

  • P. C. A. Louis and the birth of clinical epidemiology.

    abstract：:Pierre Charles Alexandre Louis (1787-1872) has been the direct or indirect mentor of influential U.S. and English scientists in public health, epidemiology, medicine, and biostatistics during the 19th and 20th century. Louis was primarily a clinician, but his name has been more closely associated with the history of e...

    journal_title：Journal of clinical epidemiology

    pub_type： 传,历史文章,杂志文章

    doi：10.1016/s0895-4356(96)00294-6

    authors： Morabia A

    更新日期：1996-12-01 00:00:00

  • An international survey and modified Delphi approach revealed numerous rapid review methods.

    abstract：OBJECTIVES:To solicit experiences with and perceptions of rapid reviews from stakeholders, including researchers, policy makers, industry, journal editors, and health care providers. STUDY DESIGN AND SETTING:An international survey of rapid review producers and modified Delphi. RESULTS:Forty rapid review producers re...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2015.08.012

    authors： Tricco AC,Zarin W,Antony J,Hutton B,Moher D,Sherifali D,Straus SE

    更新日期：2016-02-01 00:00:00

  • External validation of prognostic models for critically ill patients required substantial sample sizes.

    abstract：OBJECTIVE:To investigate the behavior of predictive performance measures that are commonly used in external validation of prognostic models for outcome at intensive care units (ICUs). STUDY DESIGN AND SETTING:Four prognostic models (Simplified Acute Physiology Score II, the Acute Physiology and Chronic Health Evaluati...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2006.08.011

    authors： Peek N,Arts DG,Bosman RJ,van der Voort PH,de Keizer NF

    更新日期：2007-05-01 00:00:00

  • Subgroup analyses of the major clinical endpoints in the Program on the Surgical Control of the Hyperlipidemias (POSCH): overall mortality, atherosclerotic coronary heart disease (ACHD) mortality, and ACHD mortality or myocardial infarction.

    abstract：:The Program on the Surgical Control of the Hyperlipidemias (POSCH) was a secondary atherosclerosis intervention trial employing partial ileal bypass surgery as the intervention modality. For this report, we analyzed 105 subgroups in 35 variables in POSCH, chosen predominantly for their potential relationship to the ri...

    journal_title：Journal of clinical epidemiology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1016/0895-4356(94)00145-g

    authors： Matts JP,Buchwald H,Fitch LL,Campos CT,Varco RL,Campbell GS,Pearce MB,Yellin AE,Smink RD Jr,Sawin HS Jr

    更新日期：1995-03-01 00:00:00

  • The use of clinical information in diagnosing chronic heart failure: a comparison between general practitioners, cardiologists, and students.

    abstract：:In a clinical judgement analysis study, 27 general practitioners, 22 cardiologists, and 21 medical students assessed 40 case vignettes with regard to the probability of heart failure, in order to study the weights of different kinds of information (cues) measured by the regression coefficients in a multiple regression...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/s0895-4356(00)00241-9

    authors： Skånér Y,Bring J,Ullman B,Strender LE

    更新日期：2000-11-01 00:00:00

  • Predictors of attrition in a longitudinal cognitive aging study: the Maastricht Aging Study (MAAS).

    abstract：:A large sample of older participants of the Maastricht Aging Study (MAAS) were compared to drop-outs at the 3-year follow-up with respect to socio-demographic, health, and cognitive characteristics. In addition, the impact of selective drop-out on measures of cognitive change was examined. To this end, hypothetical sc...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/s0895-4356(01)00473-5

    authors： Van Beijsterveldt CE,van Boxtel MP,Bosma H,Houx PJ,Buntinx F,Jolles J

    更新日期：2002-03-01 00:00:00

  • Differential recall as a source of bias in epidemiologic research.

    abstract：:Differential recall between compared groups is discussed most often in the context of case-control studies. Cases, compared to controls, are suspected of providing a more complete report of their true exposure to an hypothesized risk factor, thereby biasing upwards the estimate of its effect. The present paper describ...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(90)90100-4

    authors： Neugebauer R,Ng S

    更新日期：1990-01-01 00:00:00

  • Statistical approaches to harmonize data on cognitive measures in systematic reviews are rarely reported.

    abstract：OBJECTIVES:To identify statistical methods for harmonization, the procedures aimed at achieving the comparability of previously collected data, which could be used in the context of summary data and individual participant data meta-analysis of cognitive measures. STUDY DESIGN AND SETTING:Environmental scan methods wer...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2014.09.003

    authors： Griffith LE,van den Heuvel E,Fortier I,Sohel N,Hofer SM,Payette H,Wolfson C,Belleville S,Kenny M,Doiron D,Raina P

    更新日期：2015-02-01 00:00:00

  • Examination by logistic regression modelling of the variables which increase the relative risk of elderly women falling compared to elderly men.

    abstract：:In a community based, prospective study to determine risk factors for falls, 465 women and 296 men 70 years and over were followed for 1 year and 507 falls were documented. A greater proportion of women (32.7%) than men (23.0%) experienced at least one fall in which there was no or minimal external contribution. Using...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(90)90110-b

    authors： Campbell AJ,Spears GF,Borrie MJ

    更新日期：1990-01-01 00:00:00

  • Item response theory detected differential item functioning between healthy and ill children in quality-of-life measures.

    abstract：OBJECTIVE:To demonstrate the value of item response theory (IRT) and differential item functioning (DIF) methods in examining a health-related quality-of-life measure in children and adolescents. STUDY DESIGN AND SETTING:This illustration uses data from 5,429 children using the four subscales of the PedsQL 4.0 Generic...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/j.jclinepi.2007.05.002

    authors： Langer MM,Hill CD,Thissen D,Burwinkle TM,Varni JW,DeWalt DA

    更新日期：2008-03-01 00:00:00

  • The validity of single-item, self-assessment questions as measures of adult physical activity.

    abstract：:Individual energy expenditure (kcal/kg/day) was calculated from a detailed set of questions from the Health Promotion and Disease Prevention Supplement of the 1985 National Health Interview Survey. Responses to three single-item, self-assessment questions were compared to the energy expenditure variable to test criter...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(90)90013-f

    authors： Weiss TW,Slater CH,Green LW,Kennedy VC,Albright DL,Wun CC

    更新日期：1990-01-01 00:00:00

  • The true treatment benefit is unpredictable in clinical trials using surrogate outcome measured with diagnostic tests.

    abstract：BACKGROUND AND OBJECTIVES:Clinical trials increasingly use results of diagnostic tests as surrogate outcomes. Our objective was to answer the following questions: (1) is the parameter measured by the reference standard a valid surrogate? (2) How does the tests accuracy influence the estimate of the treatment benefit on...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jclinepi.2005.02.024

    authors： Kassaï B,Shah NR,Leizorovicza A,Cucherat M,Gueyffier F,Boissel JP

    更新日期：2005-10-01 00:00:00

  • Estimating the contribution of individual risk factors to disease in a person with more than one risk factor.

    abstract：:Various measures have been proposed to express the excess risk of an outcome attributable to one particular risk factor, such as attributable risk and risk fraction. However, there is sometimes a need, both in epidemiological studies and in awarding compensation in legal cases, to simultaneously consider the contribut...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/s0895-4356(02)00388-8

    authors： McElduff P,Attia J,Ewald B,Cockburn J,Heller R

    更新日期：2002-06-01 00:00:00

  • Impact of reminders and method of questionnaire distribution on patient response to mail-back satisfaction survey.

    abstract：:Nonresponse and methods of data collection could affect satisfaction measurement. The goal of this study was to estimate the impact of (1) nonresponse and (2) distribution method on evaluation of patient satisfaction in a mail-back study measuring patient opinion of medical and nursing care. The study was conducted in...

    journal_title：Journal of clinical epidemiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/s0895-4356(01)00387-0

    authors： Gasquet I,Falissard B,Ravaud P

    更新日期：2001-11-01 00:00:00

  • Comparison of "Rose Questionnaire Angina" to exercise thallium scintigraphy: different findings in males and females.

    abstract：:Validation of the London School of Hygiene (Rose) Questionnaire with objective measures of myocardial ischemia is incomplete. Therefore, we compared the Rose Questionnaire with exercise thallium-201 myocardial scintigraphy in 147 male and 97 female patients with chest pain referred for clinical exercise testing. Of th...

    journal_title：Journal of clinical epidemiology

    pub_type： 杂志文章

    doi：10.1016/0895-4356(92)90048-r

    authors： Garber CE,Carleton RA,Heller GV

    更新日期：1992-07-01 00:00:00