听力与言语-语言病理学

行为科学

医学伦理学

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  • Antidepressant prescriptions have not fully reflected evolving evidence from cumulative network meta-analyses and guideline recommendations.

    abstract:OBJECTIVES:This study compares three major elements of evidence-based medicine (EBM) practices, namely evidence synthesis, clinical practice guidelines (CPGs), and real-world prescriptions in the United States, regarding antidepressant treatments of major depression over the past 3 decades. STUDY DESIGN AND SETTING:We...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.12.023

    authors: Luo Y,Ostinelli EG,Sahker E,Chaimani A,Kataoka Y,Ogawa Y,Cipriani A,Salanti G,Furukawa TA

    更新日期:2021-01-06 00:00:00

  • Evidence-Based Research Series-Paper 3: Using an Evidence-Based Research approach to place your results into context after the study is performed to ensure usefulness of the conclusion.

    abstract:BACKGROUND AND OBJECTIVE:There is considerable actual and potential waste in research. Using evidence-based research (EBR) can ensure the value of a new study. The aim of this article, the third in a series, is to describe an EBR approach to putting research results into context. STUDY DESIGN AND SETTING:EBR is the us...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.07.021

    authors: Lund H,Juhl CB,Nørgaard B,Draborg E,Henriksen M,Andreasen J,Christensen R,Nasser M,Ciliska D,Tugwell P,Clarke M,Blaine C,Martin J,Ban JW,Brunnhuber K,Robinson KA,Evidence-Based Research Network.

    更新日期:2021-01-01 00:00:00

  • Measuring importance of outcomes to patients: a cross-sectional survey for the German anal cancer guideline.

    abstract:OBJECTIVE:We aimed to generate evidence on patients' values and preferences to inform the development of the German national Evidence-based Anal Cancer Guideline. STUDY DESIGN AND SETTING:We developed a list of health outcomes based on a systematic search. We then asked anal cancer patients and experts of the guidelin...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.09.026

    authors: Werner RN,Gaskins M,Dressler C,Nast A,Schaefer C,Aigner F,Siegel R

    更新日期:2021-01-01 00:00:00

  • Redundant meta-analyses are common in genetic epidemiology.

    abstract:OBJECTIVES:The massive growth in the publication of meta-analyses may cause redundancy and wasted efforts. We performed a metaepidemiologic study to evaluate the extent of potential redundancy in published meta-analyses in genetic epidemiology. STUDY DESIGN AND SETTING:Using a sample of 38 index meta-analyses of genet...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2020.05.035

    authors: Sigurdson MK,Khoury MJ,Ioannidis JPA

    更新日期:2020-11-01 00:00:00

  • Evidence of survival benefit was often ambiguous in randomized trials of cancer treatments.

    abstract:OBJECTIVES:The objective of the study is to estimate the proportion of statistically significant survival improvements reported in randomized trials of cancer treatments that are also compatible with a clinically negligible benefit. STUDY DESIGN AND SETTING:This is a cross-sectional study of reports of randomized clin...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.06.026

    authors: Perneger TV,Brindel P,Combescure C,Gayet-Ageron A

    更新日期:2020-11-01 00:00:00

  • Controversy and Debate Series on Core Outcome Sets. Paper 1: Improving the generalizability and credibility of core outcome sets (COS) by a large and international participation of diverse stakeholders.

    abstract::Core outcome sets (COSs) are agreed-on standardized sets of outcomes that should be minimally measured in all trials of a given disease. To enhance the uptake of COSs in trials, their generalizability should be increased by a change in the number and diversity of stakeholders involved in their development. Also, their...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.01.004

    authors: Chevance A,Tran VT,Ravaud P

    更新日期:2020-09-01 00:00:00

  • A large number of COVID-19 interventional clinical trials were registered soon after the pandemic onset: a descriptive analysis.

    abstract:BACKGROUND AND OBJECTIVE:There is a pressing need for evidence-based interventions to address the devastating clinical and public health effects of the coronavirus disease 2019 (COVID-19) pandemic. The number of registered trials related to COVID-19 is increasing by the day. The objective of this study was to describe ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.06.005

    authors: Nasrallah AA,Farran SH,Nasrallah ZA,Chahrour MA,Salhab HA,Fares MY,Khachfe HH,Akl EA

    更新日期:2020-09-01 00:00:00

  • In network meta-analysis, most of the information comes from indirect evidence: empirical study.

    abstract:OBJECTIVES:Network meta-analysis (NMA) may produce more precise estimates of treatment effects than pairwise meta-analysis. We examined the relative contribution of network paths of different lengths to estimates of treatment effects. STUDY DESIGN AND SETTING:We analyzed 213 published NMAs. We categorized network shap...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.04.009

    authors: Papakonstantinou T,Nikolakopoulou A,Egger M,Salanti G

    更新日期:2020-08-01 00:00:00

  • Half of Cochrane reviews were published more than 2 years after the protocol.

    abstract:OBJECTIVES:The objective of the study is to examine the time from publication of the protocol for a Cochrane review to publication of the Cochrane review for the entire Cochrane Database of Systematic Reviews (CDSR). STUDY DESIGN AND SETTINGS:Cochrane reviews from the CDSR published between 1995 and 2019 were assessed...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2020.05.011

    authors: Andersen MZ,Gülen S,Fonnes S,Andresen K,Rosenberg J

    更新日期:2020-08-01 00:00:00

  • An embedded mixed-methods study highlighted a lack of discussions on retention in clinical trial consultations.

    abstract:OBJECTIVES:This study investigated trial consultations to identify whether and to what extent discussions of retention are present. STUDY DESIGN AND SETTING:This embedded mixed-methods study design included a purposive sample of audio-recorded trial consultations obtained from four sites of a large multicenter UK-base...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.03.011

    authors: Tunji-Ajayi P,Duncan EM,Gillies K

    更新日期:2020-07-01 00:00:00

  • Inferential reproduction analysis demonstrated that "paracetamol for acute low back pain" trial conclusions were reproducible.

    abstract:OBJECTIVES:The aim of this study was to reanalyze and reinterpret data obtained in Paracetamol in Acute Low Back Pain (PACE), the first large randomized controlled trial evaluating the efficacy of paracetamol in acute low back pain, to assess the inferential reproducibility of the original conclusions. STUDY DESIGN AN...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jclinepi.2020.01.010

    authors: Schreijenberg M,Chiarotto A,Mauff KAL,Lin CC,Maher CG,Koes BW

    更新日期:2020-05-01 00:00:00

  • Optimal sampling in derivation studies was associated with improved discrimination in external validation for heart failure prognostic models.

    abstract:OBJECTIVES:The objective of the study was to identify determinants of external validity of prognostic models. STUDY DESIGN AND SETTING:We systematically searched for studies reporting prognostic models of heart failure (HF) and examined their performance for predicting 30-day death in a cohort of consecutive 3,452 acu...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2020.01.011

    authors: Iwakami N,Nagai T,Furukawa TA,Tajika A,Onishi A,Nishimura K,Ogata S,Nakai M,Takegami M,Nakano H,Kawasaki Y,Alba AC,Guyatt GH,Shiraishi Y,Kohsaka S,Kohno T,Goda A,Mizuno A,Yoshikawa T,Anzai T,investigators for the

    更新日期:2020-05-01 00:00:00

  • Conflict of interest as ethical shorthand: understanding the range and nature of "non-financial conflict of interest" in biomedicine.

    abstract:OBJECTIVES:The aim of the study was to identify the range of issues labeled as "non-financial conflicts of interest" in biomedicine, articulate the associated concerns, and analyze the implications of defining these issues as conflicts of interest. STUDY DESIGN AND SETTING:This was a qualitative study, triangulating d...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.12.014

    authors: Grundy Q,Mayes C,Holloway K,Mazzarello S,Thombs BD,Bero L

    更新日期:2020-04-01 00:00:00

  • Frequent inappropriate use of unweighted summary statistics in systematic reviews of pathogen genotypes or genogroups.

    abstract:OBJECTIVES:Our study aimed to systematically assess and report the methodological quality used in epidemiological systematic reviews (SRs) and meta-analysis (MA) of pathogen genotypes/genogroups. STUDY DESIGN AND SETTING:Nine electronic databases and manual search of reference lists were used to identify relevant stud...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.11.009

    authors: Tran L,Nhu Y M,Le Ba Nghia T,Hendam A,Vuong NL,Alzalal E,Sayed AM,Hussain MM,Sharma A,Tieu T,Mathenge PG,Hirayama K,Alexander N,Huy NT

    更新日期:2020-03-01 00:00:00

  • Overviews of reviews incompletely report methods for handling overlapping, discordant, and problematic data.

    abstract:OBJECTIVES:The aim of the study was to assess the completeness of reporting of methods in overviews. STUDY DESIGN AND SETTING:Assessment of the adequacy of reporting of methods in a random sample of 50 overviews was based on a published framework of methods for conducting overviews. Descriptive summary statistics were...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.09.025

    authors: Lunny C,Brennan SE,Reid J,McDonald S,McKenzie JE

    更新日期:2020-02-01 00:00:00

  • Nonrandomized studies using causal-modeling may give different answers than RCTs: a meta-epidemiological study.

    abstract:OBJECTIVES:To evaluate how estimated treatment effects agree between nonrandomized studies using causal modeling with marginal structural models (MSM-studies) and randomized trials (RCTs). STUDY DESIGN:Meta-epidemiological study. SETTING:MSM-studies providing effect estimates on any healthcare outcome of any treatmen...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.10.012

    authors: Ewald H,Ioannidis JPA,Ladanie A,Mc Cord K,Bucher HC,Hemkens LG

    更新日期:2020-02-01 00:00:00

  • GRADE guidelines 27: how to calculate absolute effects for time-to-event outcomes in summary of findings tables and Evidence Profiles.

    abstract:OBJECTIVES:To provide GRADE guidance on how to prepare Summary of Findings tables and Evidence Profiles for time-to-event outcomes with a focus on the calculation of the corresponding absolute effect estimates. STUDY DESIGN AND SETTING:This guidance was justified by a research project identifying frequent errors and l...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.10.015

    authors: Skoetz N,Goldkuhle M,van Dalen EC,Akl EA,Trivella M,Mustafa RA,Nowak A,Dahm P,Schünemann H,Bender R,GRADE Working Group.

    更新日期:2020-02-01 00:00:00

  • P value-driven methods were underpowered to detect publication bias: analysis of Cochrane review meta-analyses.

    abstract:OBJECTIVES:The aim of the study was to investigate the effect of number of studies in a meta-analysis on the detection of publication bias using P value-driven methods. METHODS:The proportion of meta-analyses detected by Egger's, Harbord's, Peters', and Begg's tests to have asymmetry suggestive of publication bias wer...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.11.011

    authors: Furuya-Kanamori L,Xu C,Lin L,Doan T,Chu H,Thalib L,Doi SAR

    更新日期:2020-02-01 00:00:00

  • The increasing complexity of the core outcomes landscape.

    abstract::In this project, we set out to identify ways to increase the uptake of core outcome sets in clinical research. In doing so, we uncovered a growing recognition, across many different health care sectors, of the need for common, relevant outcomes to improve the quality of decision-making. This has led to a plethora of p...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.05.016

    authors: Moloney RM,Messner DA,Tunis SR

    更新日期:2019-12-01 00:00:00

  • Publication bias may exist among prognostic accuracy studies of middle cerebral artery Doppler ultrasound.

    abstract:OBJECTIVES:The objective of this study was to assess if there is evidence of publication bias in prognostic accuracy studies of middle cerebral artery (MCA) or cerebroplacental ratio (CPR) for adverse perinatal outcome. STUDY DESIGN AND SETTING:We queried PubMed, EMBASE, the Cochrane Library, and ClinicalTrials.gov an...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.07.016

    authors: Vollgraff Heidweiller-Schreurs CA,Korevaar DA,Mol BWJ,Bax CJ,de Groot CJM,de Boer MA,Bossuyt PMM

    更新日期:2019-12-01 00:00:00

  • Using the STROBE statement: survey findings emphasized the role of journals in enforcing reporting guidelines.

    abstract:OBJECTIVES:The objective of the study was to identify factors affecting the use of the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement, specifically authors' attitudes toward and experiences with it. STUDY DESIGN AND SETTING:An online survey was distributed to authors of observa...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.07.019

    authors: Sharp MK,Bertizzolo L,Rius R,Wager E,Gómez G,Hren D

    更新日期:2019-12-01 00:00:00

  • Result dissemination from clinical trials conducted at German university medical centers was delayed and incomplete.

    abstract:OBJECTIVES:Timely and comprehensive reporting of clinical trial results builds the backbone of evidence-based medicine and responsible research. The proportion of timely disseminated trial results can inform alternative national and international benchmarking of university medical centers (UMCs). STUDY DESIGN AND SETT...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.06.002

    authors: Wieschowski S,Riedel N,Wollmann K,Kahrass H,Müller-Ohlraun S,Schürmann C,Kelley S,Kszuk U,Siegerink B,Dirnagl U,Meerpohl J,Strech D

    更新日期:2019-11-01 00:00:00

  • A systematic review of core outcome set development studies demonstrates difficulties in defining unique outcomes.

    abstract:OBJECTIVES:Core outcome set (COS) development often begins with a systematic review to identify outcomes. Reviews frequently show heterogeneity in numbers of outcomes reported across trials. Contributing to this is a lack of a uniform definition for an outcome. This study proposes a first working definition for a uniqu...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.06.016

    authors: Young AE,Brookes ST,Avery KNL,Davies A,Metcalfe C,Blazeby JM

    更新日期:2019-11-01 00:00:00

  • Decision analytic modeling was useful to assess the impact of a prediction model on health outcomes before a randomized trial.

    abstract:OBJECTIVE:To demonstrate how decision analytic models (DAMs) can be used to quantify impact of using a (diagnostic or prognostic) prediction model in clinical practice and provide general guidance on how to perform such assessments. STUDY DESIGN AND SETTING:A DAM was developed to assess the impact of using the HEART s...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.07.010

    authors: Jenniskens K,Lagerweij GR,Naaktgeboren CA,Hooft L,Moons KGM,Poldervaart JM,Koffijberg H,Reitsma JB

    更新日期:2019-11-01 00:00:00

  • Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies.

    abstract:BACKGROUND AND OBJECTIVE:Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by five methodological and statistical characteristics of pivotal trial evidence that were described by the U.S....

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.05.033

    authors: Ladanie A,Speich B,Briel M,Sclafani F,Bucher HC,Agarwal A,Ioannidis JPA,Pereira TV,Kasenda B,Hemkens LG

    更新日期:2019-10-01 00:00:00

  • Psychometric evaluation supported construct validity, temporal stability, and responsiveness of the Osteoarthritis Questionnaire.

    abstract:OBJECTIVES:The Osteoarthritis Questionnaire (OA-Quest) is a new measure of individual burden of osteoarthritis, composing seven brief (4-11 items; total 42 items), independent scales. This study describes the psychometric evaluation of the OA-Quest. Specifically, temporal stability, convergent and discriminant validity...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.06.001

    authors: Busija L,Osborne RH,Tatangelo G,Niutta S,Buchbinder R

    更新日期:2019-10-01 00:00:00

  • Clinical replicability of rehabilitation interventions in randomized controlled trials reported in main journals is inadequate.

    abstract:OBJECTIVE:The objective of this study was to study if randomized controlled trials (RCTs) in rehabilitation (a field where complex interventions prevail) published in main journals include all the details needed to replicate the intervention in clinical practice (clinical replicability). STUDY DESIGN AND SETTING:Forty...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.06.008

    authors: Negrini S,Arienti C,Pollet J,Engkasan JP,Francisco GE,Frontera WR,Galeri S,Gworys K,Kujawa J,Mazlan M,Rathore FA,Schillebeeckx F,Kiekens C,REREP study participants.

    更新日期:2019-10-01 00:00:00

  • Limited evidence exists on the effectiveness of education and training interventions on trial recruitment; a systematic review.

    abstract:OBJECTIVE:The objective of this study was to examine the effectiveness of education and training interventions on recruitment to randomized and non-randomized trials. STUDY DESIGN AND SETTING:A systematic review of the effectiveness of education and training interventions for recruiters to trials. The review included ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.05.013

    authors: Delaney H,Devane D,Hunter A,Hennessy M,Parker A,Murphy L,Cronin P,Smith V

    更新日期:2019-09-01 00:00:00

  • Risk of bias assessments for blinding of participants and personnel in Cochrane reviews were frequently inadequate.

    abstract:OBJECTIVES:The objective of this study was to analyze adequacy of judgments about risk of bias (RoB) for blinding of participants and personnel (performance bias) in Cochrane systematic reviews of randomized controlled trials (RCTs). STUDY DESIGN AND SETTING:We extracted judgments and supporting comments for performan...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.05.012

    authors: Barcot O,Boric M,Dosenovic S,Poklepovic Pericic T,Cavar M,Puljak L

    更新日期:2019-09-01 00:00:00

  • Research environment of clinician-scientists in China in health policy/health services research.

    abstract:OBJECTIVES:The aim of the study was to describe the research environment of scientists in health services and policy research in China. STUDY DESIGN:Study was conducted during the 2016 Westlake Youth Forum with grantees of China Medical Board and key informants. Mixed methods used anonymous, survey of grantees, semist...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.05.004

    authors: Gao M,Zhou L,Tang K,Liang MH

    更新日期:2019-08-01 00:00:00

  • The statistical significance of meta-analyses is frequently fragile: definition of a fragility index for meta-analyses.

    abstract:OBJECTIVES:Meta-analyses inform clinical practice by summarizing treatment effect estimates based on results from several trials. However, the statistical significance of a meta-analysis (i.e., whether the pooled treatment effect is statistically significant or not) may rely on the outcome of only a few patients from s...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.03.012

    authors: Atal I,Porcher R,Boutron I,Ravaud P

    更新日期:2019-07-01 00:00:00

  • Including papers in languages other than English in systematic reviews: important, feasible, yet often omitted.

    abstract::A truly international and systematic review (SR) identifies and synthesizes relevant evidence regardless of the geographical provenance or language of publication. Despite recommendations, international SRs continue to exclude papers in languages other than English (LOE) at searching, screening, and analysis phases ei...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.03.004

    authors: Walpole SC

    更新日期:2019-07-01 00:00:00

  • Structured decision-making drives guidelines panels' recommendations "for" but not "against" health interventions.

    abstract:BACKGROUND AND OBJECTIVES:The determinants of guideline panels' recommendations remain uncertain. The objective of this study was to investigate factors considered by members of 8 panels convened by the American Society of Hematology (ASH) to develop guidelines using Grading of Recommendations Assessment, Development, ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.02.009

    authors: Djulbegovic B,Reljic T,Elqayam S,Cuker A,Hozo I,Zhou Q,Li SA,Alexander P,Nieuwlaat R,Wiercioch W,Schünemann H,Guyatt G

    更新日期:2019-06-01 00:00:00

  • Most noninferiority trials were not designed to preserve active comparator treatment effects.

    abstract:OBJECTIVES:To evaluate whether noninferiority trials are designed to adequately preserve the historical treatment effect of their active comparators. STUDY DESIGN AND SETTING:We reviewed 162 noninferiority trials published in high-impact medical journals. We assessed whether trials were designed to ensure that interve...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2019.03.003

    authors: Tsui M,Rehal S,Jairath V,Kahan BC

    更新日期:2019-06-01 00:00:00

  • Rapid reviews may produce different results to systematic reviews: a meta-epidemiological study.

    abstract:OBJECTIVE:To simulate possible changes in systematic review results if rapid review methods were used. STUDY DESIGN AND SETTING:We recalculated meta-analyses for binary primary outcomes in Cochrane systematic reviews, simulating rapid review methods. We simulated searching only PubMed, excluding older articles (5, 7, ...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jclinepi.2018.12.015

    authors: Marshall IJ,Marshall R,Wallace BC,Brassey J,Thomas J

    更新日期:2019-05-01 00:00:00

  • Real-world evidence was feasible for estimating effectiveness of chemotherapy in breast cancer: a cohort study.

    abstract:OBJECTIVE:Evidence-based guidelines recommend adjuvant chemotherapy in early stage breast cancer whenever treatment benefit is considered sufficient to outweigh the associated risks. However, many groups of patients were either excluded from or underrepresented in the clinical trials that form the evidence base for thi...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2019.01.006

    authors: Gray E,Marti J,Brewster DH,Wyatt JC,Piaget-Rossel R,Hall PS

    更新日期:2019-05-01 00:00:00

  • Methodological review showed correct absolute effect size estimates for time-to-event outcomes in less than one-third of cancer-related systematic reviews.

    abstract:OBJECTIVES:To evaluate in how many cancer-related Cochrane reviews hazard ratio (HR)-based absolute effects in summary of findings (SoF) tables have been correctly calculated and reported. STUDY DESIGN AND SETTING:We identified all Cochrane cancer intervention reviews that reported an HR for at least one outcome and p...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jclinepi.2018.12.006

    authors: Skoetz N,Goldkuhle M,Weigl A,Dwan K,Labonté V,Dahm P,Meerpohl JJ,Djulbegovic B,van Dalen EC

    更新日期:2019-04-01 00:00:00

  • Getting more out of meta-analyses: a new approach to meta-analysis in light of unexplained heterogeneity.

    abstract:BACKGROUND AND OBJECTIVES:Meta-analyses sometimes summarize results in the presence of substantial unexplained between-study heterogeneity. As GRADE criteria highlight, unexplained heterogeneity reduces certainty in the evidence, resulting in limited confidence in average effect estimates. The aim of this paper is to p...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2018.11.023

    authors: Saad A,Yekutieli D,Lev-Ran S,Gross R,Guyatt G

    更新日期:2019-03-01 00:00:00

  • Increased risks for random errors are common in outcomes graded as high certainty of evidence.

    abstract:OBJECTIVES:The aim of article was to assess the risk for random errors in outcomes graded as high certainty of evidence (CoE). STUDY DESIGN AND SETTING:We randomly selected 100 Cochrane reviews with dichotomous outcomes rated as high CoE using Grading of Recommendations Assessment, Development, and Evaluation. To dete...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2018.10.009

    authors: Gartlehner G,Nussbaumer-Streit B,Wagner G,Patel S,Swinson-Evans T,Dobrescu A,Gluud C

    更新日期:2019-02-01 00:00:00

  • Toward a theory-led metaframework for considering socioeconomic health inequalities within systematic reviews.

    abstract:OBJECTIVES:To develop a theory-led framework to inform reviewers' understanding of what, how, and why health care interventions may lead to differential effects across socioeconomic groups. STUDY DESIGN AND SETTING:A metaframework approach combined two theoretical perspectives (socioeconomic health inequalities and co...

    journal_title:Journal of clinical epidemiology

    pub_type: 杂志文章

    doi:10.1016/j.jclinepi.2018.08.008

    authors: Maden M,McMahon N,Booth A,Dickson R,Paisley S,Gabbay M

    更新日期:2018-12-01 00:00:00

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