Successful conservative treatment of rheumatoid subaxial subluxation resulting in improvement of myelopathy, reduction of subluxation, and stabilisation of the cervical spine. A report of two cases.

abstract：OBJECTIVE:To compare individually tailored, based on trimestrial biological parameter monitoring, to fixed-schedule rituximab reinfusion for remission maintenance of antineutrophil cytoplasm antibody (ANCA)-associated vasculitides (AAVs). METHODS:Patients with newly diagnosed or relapsing granulomatosis with polyangii...

journal_title：Annals of the rheumatic diseases

authors： Charles P,Terrier B,Perrodeau É,Cohen P,Faguer S,Huart A,Hamidou M,Agard C,Bonnotte B,Samson M,Karras A,Jourde-Chiche N,Lifermann F,Gobert P,Hanrotel-Saliou C,Godmer P,Martin-Silva N,Pugnet G,Matignon M,Aumaitre O,

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVES:To examine the long term prognosis in patients with fibromyalgia (FM). METHODS:Forty five of 70 patients who had participated in a three week trial six years earlier completed again the same questionnaires used previously. RESULTS:Most symptoms had remained stable. Pain had increased, but some aspects of q...

journal_title：Annals of the rheumatic diseases

authors： Baumgartner E,Finckh A,Cedraschi C,Vischer TL

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To assess how socioeconomic deprivation influences the presentation, treatment, and outcome of patients with rheumatoid arthritis (RA). METHODS:Three year follow up of 869 consecutive patients with RA from nine hospital rheumatology clinics, with patients categorised by the Carstairs deprivation score of the...

journal_title：Annals of the rheumatic diseases

authors：

更新日期：2000-10-01 00:00:00

abstract：:This review assesses the risk assessment of cardiovascular disease (CVD) in rheumatoid arthritis (RA) and how non-invasive imaging modalities may improve risk stratification in future. RA is common and patients are at greater risk of CVD than the general population. Cardiovascular (CV) risk stratification is recommend...

journal_title：Annals of the rheumatic diseases

authors： Fent GJ,Greenwood JP,Plein S,Buch MH

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Myeloid inhibitory C-type lectin-like receptor (MICL, Clec12A) is a C-type lectin receptor (CLR) expressed predominantly by myeloid cells. Previous studies have suggested that MICL is involved in controlling inflammation. OBJECTIVE:To determine the role of this CLR in inflammatory pathology using Clec12A(-/...

journal_title：Annals of the rheumatic diseases

authors： Redelinghuys P,Whitehead L,Augello A,Drummond RA,Levesque JM,Vautier S,Reid DM,Kerscher B,Taylor JA,Nigrovic PA,Wright J,Murray GI,Willment JA,Hocking LJ,Fernandes MJ,De Bari C,Mcinnes IB,Brown GD

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Hand exercises are recommended for patients with hand osteoarthritis (HOA), though evidence for their effect is conflicting. OBJECTIVE:To evaluate, in a randomised controlled trial, the effect of HOA information plus home-based hand exercises (exercise group) compared with information only (control group) i...

journal_title：Annals of the rheumatic diseases

authors： Hennig T,Hæhre L,Hornburg VT,Mowinckel P,Norli ES,Kjeken I

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To investigate the production of the matrix metalloproteinase (MMP), collagenase (MMP-1), and its natural inhibitor, the tissue inhibitor of metalloproteinases (TIMP) by diseased human tendon samples in organ culture. METHODS:Portions of tendons were excised from the shoulders of patients undergoing shoulder...

journal_title：Annals of the rheumatic diseases

authors： Dalton S,Cawston TE,Riley GP,Bayley IJ,Hazleman BL

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:Progranulin (PGRN) was previously isolated as an osteoarthritis (OA)-associated growth factor. Additionally, PGRN was found to play a therapeutic role in inflammatory arthritis mice models through antagonising tumour necrosis factor α (TNF-α). This study was aimed at investigating the role of PGRN in degradat...

journal_title：Annals of the rheumatic diseases

authors： Zhao YP,Liu B,Tian QY,Wei JL,Richbourgh B,Liu CJ

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To investigate the long-term effects of induction therapy with adalimumab (ADA) plus methotrexate (MTX) in comparison with placebo (PBO) plus MTX in DMARD-naïve patients with active early rheumatoid arthritis (RA). METHODS:Patients with active early RA (disease duration of ≤12 months) were randomly assigned ...

journal_title：Annals of the rheumatic diseases

authors： Detert J,Bastian H,Listing J,Weiß A,Wassenberg S,Liebhaber A,Rockwitz K,Alten R,Krüger K,Rau R,Simon C,Gremmelsbacher E,Braun T,Marsmann B,Höhne-Zimmer V,Egerer K,Buttgereit F,Burmester GR

更新日期：2013-06-01 00:00:00

abstract：:HLA A, B, and C antigens were studied in 25 patients with ankylosing hyperostosis. There was no evidence of an increased frequency of any antigen in association with the condition itself. However, a high frequency of several antigens was found, reflecting the predominance of Jewish patients in the series. ...

journal_title：Annals of the rheumatic diseases

authors： Perry JD,Wolf H,Festenstein H,Storey GO

更新日期：1979-02-01 00:00:00

abstract：OBJECTIVE:Notch signalling pathways are critical for angiogenesis and endothelial cell (EC) fate; however the mechanisms regulating these processes in the inflamed joint remain to be elucidated. Here, we examine whether Notch signalling mediates vascular endothelial growth factor (VEGF) and angiopoietin 2 (Ang2)-induce...

journal_title：Annals of the rheumatic diseases

authors： Gao W,Sweeney C,Walsh C,Rooney P,McCormick J,Veale DJ,Fearon U

更新日期：2013-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the effect of infliximab on health related quality of life (HRQoL) and physical function in patients with active psoriatic arthritis (PsA) in the IMPACT 2 trial. METHODS:200 patients with PsA unresponsive to conventional treatment were randomised to intravenous infusions of infliximab 5 mg/kg or...

journal_title：Annals of the rheumatic diseases

authors： Kavanaugh A,Antoni C,Krueger GG,Yan S,Bala M,Dooley LT,Beutler A,Guzzo C,Gladman D

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:Chondroitin sulfate 800 mg/day (CS) pharmaceutical-grade in the management of symptomatic knee osteoarthritis consistent with the European Medicines Agency guideline. METHODS:A prospective, randomised, 6-month, 3-arm, double-blind, double-dummy, placebo and celecoxib (200 mg/day)-controlled trial assessing ...

journal_title：Annals of the rheumatic diseases

authors： Reginster JY,Dudler J,Blicharski T,Pavelka K

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Osteoarthritis of the hands is a prevalent musculoskeletal disease with a considerable effect on patients' lives, but knowledge and research results in the field of hand osteoarthritis are limited. Therefore, the Disease Characteristics in Hand OA (DICHOA) initiative was founded in early 2005 with the aim of...

journal_title：Annals of the rheumatic diseases

authors： Kloppenburg M,Stamm T,Watt I,Kainberger F,Cawston TE,Birrell FN,Petersson IF,Saxne T,Kvien TK,Slatkowsky-Christensen B,Dougados M,Gossec L,Breedveld FC,Smolen JS

更新日期：2007-09-01 00:00:00

abstract：:Leucopenia appears to be a more frequent complication of sulphasalazine treatment in rheumatoid arthritis than in inflammatory bowel disease and poses a management problem. In this study leucopenia was found in 20 patients, 14 of whom were participating in prospective studies (252 patients), giving an incidence of 5.6...

journal_title：Annals of the rheumatic diseases

authors： Marabani M,Madhok R,Capell HA,Hunter JA

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVES:Although TNF-α inhibitors' striking effect on clinical symptoms have revolutionised the treatment of ankylosing spondylitis (AS), no certain influence on the development of spinal ankylosis and joint destruction has been documented. We wished to investigate whether improved treatment has affected the use of ...

journal_title：Annals of the rheumatic diseases

authors： Nystad TW,Furnes O,Havelin LI,Skredderstuen AK,Lie SA,Fevang BT

更新日期：2014-06-01 00:00:00

abstract：:Two patients with sickle cell disease presented with joint pain and early x-ray evidence of articular cartilage loss. Both later developed increasingly destructive arthritis with chronic synovitis identified in synovial biopsies. One patient developed demonstrable aseptic necrosis. Destructive arthropathy is much less...

journal_title：Annals of the rheumatic diseases

authors： Schumacher HR,Dorwart BB,Bond J,Alavi A,Miller W

更新日期：1977-10-01 00:00:00

abstract：:A controlled study compared 6 months' treatment of 60 patients with rheumatoid arthritis (RA). Half were randomly allocated to treatment with chloroquine 250 mg daily, the other half dapsone 100 mg daily (50 mg/day for the first 7 days) following a one-month run-in assessment period. All patients had active or progres...

journal_title：Annals of the rheumatic diseases

authors： Fowler PD,Shadforth MF,Crook PR,Lawton A

更新日期：1984-04-01 00:00:00

abstract：OBJECTIVE:While gout is associated with cardiovascular (CV)-metabolic comorbidities and their sequelae, the antioxidant effects of uric acid may have neuroprotective benefits. We evaluated the potential impact of incident gout on the risk of developing Alzheimer's disease (AD) in a general population context. METHODS:...

journal_title：Annals of the rheumatic diseases

authors： Lu N,Dubreuil M,Zhang Y,Neogi T,Rai SK,Ascherio A,Hernán MA,Choi HK

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:To assess the usefulness of high resolution computed tomography (HRCT) of the lungs in patients with rheumatoid arthritis (RA) with and without respiratory symptoms. PATIENTS AND METHODS:Eighty eight RA patients with a mean duration of disease 12 (SD 8) years were evaluated. Eleven patients were excluded bec...

journal_title：Annals of the rheumatic diseases

authors： Cortet B,Flipo RM,Rémy-Jardin M,Coquerelle P,Duquesnoy B,Rêmy J,Delcambre B

更新日期：1995-10-01 00:00:00

abstract：:Spontaneous production of the interferon induced enzyme 2',5'-oligoadenylate synthetase (2',5'-A synthetase) was significantly greater in blood lymphocytes of patients with systemic lupus erythematosus (SLE), Behçet's syndrome, and rheumatoid arthritis than in control lymphocytes. Alpha interferon (IFN-alpha) induced ...

journal_title：Annals of the rheumatic diseases

authors： Hylton W,Cayley J,Dore C,Denman AM

更新日期：1986-03-01 00:00:00

abstract：OBJECTIVES:To determine whether hormonal dysfunction involving the hypothalamic-pituitary-adrenal (HPA) axis, prolactin (PRL) secretion, and sex hormone status contribute to development of systemic lupus erythematosus (SLE). METHODS:11 patients with SLE and 9 healthy controls were tested for their total anterior pitui...

journal_title：Annals of the rheumatic diseases

authors： Köller MD,Templ E,Riedl M,Clodi M,Wagner O,Smolen JS,Luger A

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To assess the expression of ICAM1, VCAM1, E-selectin, CD44, and TNF alpha in labial salivary glands of patients with rheumatoid vasculitis. METHODS:Labial salivary glands from six patients with rheumatoid vasculitis before and after treatment, six aged matched rheumatoid arthritis patients without clinical e...

journal_title：Annals of the rheumatic diseases

authors： Flipo RM,Cardon T,Copin MC,Vandecandelaere M,Duquesnoy B,Janin A

更新日期：1997-01-01 00:00:00

abstract：OBJECTIVE:To investigate the possibility of drug-free remission in patients with psoriatic arthritis (PsA) in continuous remission. METHODS:Prospective observational study in disease-modifying antirheumatic drug (DMARD)-treated PsA patients in continuous disease remission (no musculoskeletal symptoms, no or minimal sk...

journal_title：Annals of the rheumatic diseases

authors： Araujo EG,Finzel S,Englbrecht M,Schreiber DA,Faustini F,Hueber A,Nas K,Rech J,Schett G

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:Systemic immunological processes are profoundly shaped by the micro-environments where antigen recognition occurs. Identifying molecular signatures distinctive of such processes is pivotal to understand pathogenic immune responses and manipulate them for therapeutic purposes. Unfortunately, direct investigat...

journal_title：Annals of the rheumatic diseases

authors： Spreafico R,Rossetti M,van Loosdregt J,Wallace CA,Massa M,Magni-Manzoni S,Gattorno M,Martini A,Lovell DJ,Albani S

更新日期：2016-02-01 00:00:00

abstract：:Heart disease is a rare but important complication of polymyositis. Diagnosis of myocardial disease is usually based on non-specific clinical, electrocardiographic, and echocardiographic data. This paper reports a case of polymyositis with myocardial disease diagnosed by myocardial imaging with radiolabelled antibody ...

journal_title：Annals of the rheumatic diseases

authors： Le Guludec D,Lhote F,Weinmann P,Royer I,Jarrousse B,Caillat-Vigneron N,Guillevin L,Moretti JL

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:Persistent fibroblast activation initiated by transforming growth factor β (TGF-β) is a fundamental event in the pathogenesis of systemic sclerosis, and its pharmacological inhibition represents a potential therapeutic strategy. The nuclear receptor, peroxisome proliferator-activated receptor γ (PPAR-γ), exe...

journal_title：Annals of the rheumatic diseases

authors： Wei J,Zhu H,Komura K,Lord G,Tomcik M,Wang W,Doniparthi S,Tamaki Z,Hinchcliff M,Distler JH,Varga J

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Primary Sjögren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. Salivary gland infiltrates, however, do not correlate well with disease symptoms, and a primary role for the salivary gland parenchyma in disease development has been suggested. Specifically, dysfunction of exocri...

journal_title：Annals of the rheumatic diseases

authors： Appel S,Le Hellard S,Bruland O,Brun JG,Omdal R,Kristjansdottir G,Theander E,Nordmark G,Kvarnström M,Eriksson P,Rönnblom L,Wahren-Herlenius M,Jonsson R

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:People with spondyloarthritis (SpA), ankylosing spondylitis (AS) and psoriatic arthritis (PsA) have identified the importance of understanding how their disease and its treatment impacts on their social roles. This requires a reliable and valid standardised measure, and this study evaluates these measurement...

journal_title：Annals of the rheumatic diseases

authors： Davis AM,Palaganas MP,Badley EM,Gladman DD,Inman RD,Gignac MA

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVES:To forecast, on the basis of the past and present position of rheumatologists in Europe, the competence needed in the future to secure and promote the specialty within the healthcare network. METHODS:Union Européenne des Médecins Spécialistes/European Board of Rheumatology (UEMS/EBR) questionnaire on (a) tr...

journal_title：Annals of the rheumatic diseases

authors： Amor B

更新日期：2000-08-01 00:00:00