Abstract:
:The genes ftsE and ftsX are organized in one operon together with ftsY. FtsY codes for the receptor of the signal recognition particle (SRP) that functions in targeting a subset of inner membrane proteins. We have found no indications for a structural relationship between FtsE/X and FtsY. Evidence is presented that FtsE and FtsX form a complex in the inner membrane that bears the characteristics of an ATP-binding cassette (ABC)-type transporter. FtsE is a hydrophilic nucleotide-binding protein that has a tendency to dimerize and associates with the inner membrane through an interaction with the integral membrane protein FtsX. An FtsE null mutant showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport.
journal_name
Mol Microbioljournal_title
Molecular microbiologyauthors
de Leeuw E,Graham B,Phillips GJ,ten Hagen-Jongman CM,Oudega B,Luirink Jdoi
10.1046/j.1365-2958.1999.01245.xsubject
Has Abstractpub_date
1999-02-01 00:00:00pages
983-93issue
3eissn
0950-382Xissn
1365-2958journal_volume
31pub_type
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