Role of psychosocial treatments in management of schizophrenia: a meta-analytic review of controlled outcome studies.

abstract：:This research studied hypotheses that positive thought disorder in schizophrenia is influenced by patients' not taking in immediate target contextual material, thereby losing vital cues that guide thought processes. We assessed 164 acute inpatients (including 55 schizophrenia and 31 bipolar disorder patients), using s...

journal_title：Schizophrenia bulletin

authors： Harrow M,Green KE,Sands JR,Jobe TH,Goldberg JF,Kaplan KJ,Martin EM

更新日期：2000-01-01 00:00:00

abstract：:Between 5% and 10% of people with psychosis will die by suicide, a rate which is 20-75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals of psychotic experiences and negative metacognitive beliefs about losing menta...

journal_title：Schizophrenia bulletin

authors： Hutton P,Di Rienzo F,Turkington D,Spencer H,Taylor P

更新日期：2019-01-01 00:00:00

abstract：:Psychotic-like experiences (PLEs) increase the risk of schizophrenia and other psychotic disorders yet are common in the community. Some PLEs, such as those associated with depression, distress, and poor functioning, may confer increased risk. The aim of this study is to determine the prevalence of PLEs in a nonpsycho...

journal_title：Schizophrenia bulletin

authors： Yung AR,Buckby JA,Cotton SM,Cosgrave EM,Killackey EJ,Stanford C,Godfrey K,McGorry PD

更新日期：2006-04-01 00:00:00

abstract：:Advances in psychopharmacology have produced medications with substantial efficacy in the treatment of positive and negative symptoms of schizophrenia and the prevention of relapse or symptom exacerbation after an acute episode. In the clinical setting, the individual patient's acceptance or rejection of prescribed ph...

journal_title：Schizophrenia bulletin

authors： Fenton WS,Blyler CR,Heinssen RK

更新日期：1997-01-01 00:00:00

abstract：:The dopamine hypothesis of schizophrenia implies that alterations in the dopamine system cause functional abnormalities in the brain that may converge to aberrant salience attribution and eventually lead to psychosis. Indeed, widespread brain disconnectivity across the psychotic spectrum has been revealed by resting-s...

journal_title：Schizophrenia bulletin

authors： Rössler J,Unterassner L,Wyss T,Haker H,Brugger P,Rössler W,Wotruba D

更新日期：2019-04-25 00:00:00

abstract：:Genetic factors are known to influence both risk for schizophrenia (SZ) and variation in brain structure. A pressing question is whether the genetic underpinnings of brain phenotype and the disorder overlap. Using multivariate analytic methods and focusing on 1,402 common single-nucleotide polymorphisms (SNPs) mapped ...

journal_title：Schizophrenia bulletin

authors： Chen J,Calhoun VD,Lin D,Perrone-Bizzozero NI,Bustillo JR,Pearlson GD,Potkin SG,van Erp TGM,Macciardi F,Ehrlich S,Ho BC,Sponheim SR,Wang L,Stephen JM,Mayer AR,Hanlon FM,Jung RE,Clementz BA,Keshavan MS,Gershon ES,Sw

更新日期：2019-01-01 00:00:00

abstract：:Catatonia is a central aspect of schizophrenia spectrum disorders (SSD) and most likely associated with abnormalities in affective, motor, and sensorimotor brain regions. However, contributions of different cortical features to the pathophysiology of catatonia in SSD are poorly understood. Here, T1-weighted structural...

journal_title：Schizophrenia bulletin

authors： Hirjak D,Kubera KM,Northoff G,Fritze S,Bertolino AL,Topor CE,Schmitgen MM,Wolf RC

更新日期：2019-10-24 00:00:00

abstract：:The purpose of the study was to examine (1) to which negative symptoms schizophrenia patients attribute distress and (2) whether clinical variables can predict the levels of reported distress. With the help of a research assistant, 86 hospitalized patients completed a self-rating scale for negative symptoms. The 21 it...

journal_title：Schizophrenia bulletin

authors： Selten JP,Wiersma D,van den Bosch RJ

更新日期：2000-01-01 00:00:00

abstract：:Instrument-based scores are often used as outcome measures. However, little is known about what changes in scores mean in terms of a clinical assessment of improvement or deterioration. The purpose of this report was to determine how much change in standard instrument scores represents a clinically detectable improvem...

journal_title：Schizophrenia bulletin

authors： Cramer J,Rosenheck R,Xu W,Henderson W,Thomas J,Charney D,Department of Veterans Affairs Cooperative Study Group on Clozapine in Refractory Schizophrenia.

更新日期：2001-01-01 00:00:00

abstract：:To better characterize hippocampal pathophysiology in schizophrenia, we conducted a longitudinal study evaluating hippocampal functional connectivity during resting state, using seeds prescribed in its anterior and posterior regions. We enrolled 34 unmedicated patients with schizophrenia or schizoaffective disorder (S...

journal_title：Schizophrenia bulletin

authors： Kraguljac NV,White DM,Hadley N,Hadley JA,Ver Hoef L,Davis E,Lahti AC

更新日期：2016-07-01 00:00:00

abstract：:While the role of childhood adversity in increasing the risk of psychosis has been extensively investigated, it is not clear what the impact of early adverse experiences is on the outcomes of psychotic disorders. Therefore, we investigated associations between childhood adversity and 1-year outcomes in 285 first-prese...

journal_title：Schizophrenia bulletin

authors： Trotta A,Murray RM,David AS,Kolliakou A,O'Connor J,Di Forti M,Dazzan P,Mondelli V,Morgan C,Fisher HL

更新日期：2016-03-01 00:00:00

abstract：:The diagnosis of schizophrenia is thought to embrace several distinct subgroups. The manifold entities in a single clinical patient group increase the variance of biological measures, deflate the group-level estimates of causal factors, and mask the presence of treatment effects. However, reliable neurobiological boun...

journal_title：Schizophrenia bulletin

authors： Pan Y,Pu W,Chen X,Huang X,Cai Y,Tao H,Xue Z,Mackinley M,Limongi R,Liu Z,Palaniyappan L

更新日期：2020-04-10 00:00:00

abstract：:The purpose of this study was to investigate the construct validity and the test-retest reliability of the willingness to pay (WTP) method for estimating health state preferences associated with side effects of antipsychotic medication. Ninety-six schizophrenia patients on antipsychotics were asked (1) how much they w...

journal_title：Schizophrenia bulletin

authors： Sevy S,Nathanson K,Schechter C,Fulop G

更新日期：2001-01-01 00:00:00

abstract：:In light of the large number of studies published since the 2004 update of Schizophrenia Patient Outcomes Research Team psychopharmacological treatment recommendations, we conducted an extensive literature review to determine whether the current psychopharmacological treatment recommendations required revision and whe...

journal_title：Schizophrenia bulletin

authors： Buchanan RW,Kreyenbuhl J,Kelly DL,Noel JM,Boggs DL,Fischer BA,Himelhoch S,Fang B,Peterson E,Aquino PR,Keller W,Schizophrenia Patient Outcomes Research Team (PORT).

更新日期：2010-01-01 00:00:00

abstract：:Evaluations by families (of chronically mentally ill individuals) of mental health professionals and resources were solicited through a mail survey. The respondents, largely better educated, white, and female, indicated a generally high level of dissatisfaction. Emotional support, information, and aftercare resources ...

journal_title：Schizophrenia bulletin

authors： Holden DF,Lewine RR

更新日期：1982-01-01 00:00:00

abstract：:The authors describe an easily administered scale being developed to assess the rejecting feelings of family respondents toward former mental patients who return to live with their families. Based upon a sample of 133 discharged mental patients and family members, the scale demonstrates a moderately high reliability (...

journal_title：Schizophrenia bulletin

authors： Kreisman DE,Simmens SJ,Joy VD

更新日期：1979-01-01 00:00:00

abstract：:Patients with schizophrenia are severely impaired in crucial aspects of neurocognitive function. This impairment is the strongest clinical correlate of poor long-term outcome and adaptive dysfunction. Reports of neurocognitive enhancement with second generation antipsychotic medications have thus offered promise for i...

journal_title：Schizophrenia bulletin

authors： Keefe RS,Mohs RC,Bilder RM,Harvey PD,Green MF,Meltzer HY,Gold JM,Sano M

更新日期：2003-01-01 00:00:00

abstract：:This article focuses on the schizophrenic disorganization syndrome, which was initially described by Bleuler (who used the term "dissociation") as lying at the heart of schizophrenia. While adopting a neo-Bleulerian approach, we describe schizophrenic disorganization using a pathogenetic hypothesis and a three-part st...

journal_title：Schizophrenia bulletin

authors： Hardy-Baylé MC,Sarfati Y,Passerieux C

更新日期：2003-01-01 00:00:00

abstract：:Staff members from nine mental health agencies were trained in psychiatric rehabilitation technology. The trainers then received intensive followup to assist them in implementing the technology in their own agencies. Evaluation of the impact of the "training of trainers" strategy suggested that mental health workers w...

journal_title：Schizophrenia bulletin

authors： Rogers ES,Cohen BF,Danley KS,Hutchinson D,Anthony WA

更新日期：1986-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Schizophrenia leads to significant personal costs matched by high economic costs. Cognitive function is a strong predictor of disabilities in schizophrenia, which underpin these costs. This study of cognitive remediation therapy (CRT), which has been shown to improve cognition and reduce disability ...

journal_title：Schizophrenia bulletin

authors： Reeder C,Harris V,Pickles A,Patel A,Cella M,Wykes T

更新日期：2014-11-01 00:00:00

abstract：:Negative and positive symptoms were investigated in a sample of 72 young schizophrenic and depressed patients at followup approximately 1 1/2 years after hospital discharge. Flat affect, poverty of speech, and psychomotor retardation were included as negative symptoms, and delusions, hallucinations, and florid thought...

journal_title：Schizophrenia bulletin

authors： Pogue-Geile MF,Harrow M

更新日期：1984-01-01 00:00:00

abstract：:Problems in psychiatric classification have impeded research into psychopathology for more than a century. Here, I briefly review several new approaches to solving this problem, including the internalizing-externalizing-psychosis spectra, the 5-factor model of psychotic symptoms, and the more recent network approach. ...

journal_title：Schizophrenia bulletin

authors： Bentall RP

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:Impaired cognition is an important dimension in psychosis and its at-risk states. Research on the value of impaired cognition for psychosis prediction in at-risk samples, however, mainly relies on study-specific sample means of neurocognitive tests, which unlike widely available general test norms are difficu...

journal_title：Schizophrenia bulletin

authors： Michel C,Ruhrmann S,Schimmelmann BG,Klosterkötter J,Schultze-Lutter F

更新日期：2014-11-01 00:00:00

abstract：:Abnormal reinforcement learning and representations of reward value are present in schizophrenia, and these impairments can manifest as deficits in risk/reward decision making. These abnormalities may be due in part to dopaminergic dysfunction within cortico-limbic-striatal circuitry. Evidence from studies with labora...

journal_title：Schizophrenia bulletin

authors： Stopper CM,Floresco SB

更新日期：2015-01-01 00:00:00

abstract：:The clinical importance of subtypes based on enduring deficit or negative symptoms was examined in a group of schizophrenic patients who were assessed twice over a 1-year period. Subgroups of patients with high levels of enduring negative or deficit symptoms, based on the Scale for the Assessment of Negative Symptoms ...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Douglas MS,Bellack AS,Morrison RL

更新日期：1991-01-01 00:00:00

abstract：:In a previous article in the Schizophrenia Bulletin (Vol. 22, No. 1, 1996), we presented findings of a study on the clinical and rehabilitative effects of work activity on 150 subjects diagnosed with schizophrenia or schizoaffective disorder. Subjects were randomly assigned to either a Pay ($3.40/hr) or No-Pay group a...

journal_title：Schizophrenia bulletin

authors： Bell MD,Lysaker PH

更新日期：1997-01-01 00:00:00

abstract：:The early detection and intervention in psychoses prior to their first episode are presently based on the symptomatic ultra-high-risk and the basic symptom criteria. Current models of symptom development assume that basic symptoms develop first, followed by attenuated and, finally, frank psychotic symptoms, though int...

journal_title：Schizophrenia bulletin

authors： Jimeno N,Gomez-Pilar J,Poza J,Hornero R,Vogeley K,Meisenzahl E,Haidl T,Rosen M,Klosterkötter J,Schultze-Lutter F

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:There is evidence of a positive association between insight and depression among patients with schizophrenia. Self-stigma was shown to play a mediating role in this association. We attempted to broaden this concept by investigating insight as a potential moderator of the association between depressive sympto...

journal_title：Schizophrenia bulletin

authors： Krupchanka D,Katliar M

更新日期：2016-05-01 00:00:00

abstract：:To understand the biological significance of a decreased platelet MAO activity in schizophrenia, it is important to answer many questions about the basic molecular properties of the enzyme. The past decade has witnessed a huge expansion of research in this area which has provided some of these answers. A wide variety ...

journal_title：Schizophrenia bulletin

authors： Edwards DJ

更新日期：1980-01-01 00:00:00

abstract：:Research on emotional processing in schizophrenia suggests relatively intact subjective responses to affective stimuli "in the moment." However, neuroimaging evidence suggests diminished activation in brain regions associated with emotional processing in schizophrenia. We asked whether given a more vulnerable cognitiv...

journal_title：Schizophrenia bulletin

authors： Becerril K,Barch D

更新日期：2011-09-01 00:00:00