The Role of Insight in Moderating the Association Between Depressive Symptoms in People With Schizophrenia and Stigma Among Their Nearest Relatives: A Pilot Study.

abstract：:Cognitive Enhancement Therapy (CET) is a developmental approach to the rehabilitation of schizophrenia patients that attempts to facilitate an abstracting and "gistful" social cognition as a compensatory alternative to the more demanding and controlled cognitive strategies that often characterize schizophrenia as well...

journal_title：Schizophrenia bulletin

authors： Hogarty GE,Flesher S

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Over the past 30 years, illness management programs and cognitive-behavioral therapy for psychosis have gained prominence in the treatment of schizophrenia. However, little is known about the long-term benefits of these types of programs when delivered during inpatient treatment following a symptom exacerbati...

journal_title：Schizophrenia bulletin

authors： Schaub A,Mueser KT,von Werder T,Engel R,Möller HJ,Falkai P

更新日期：2016-07-01 00:00:00

abstract：:In follow-up from evidence obtained in linkage studies, systematic linkage disequilibrium mapping within chromosomal region 13q33 has led to the identification of a schizophrenia susceptibility locus which harbors the genes G72 and G30. These association findings have been replicated in several independent schizophren...

journal_title：Schizophrenia bulletin

authors： Abou Jamra R,Schmael C,Cichon S,Rietschel M,Schumacher J,Nöthen MM

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVE:Impaired cognition is an important dimension in psychosis and its at-risk states. Research on the value of impaired cognition for psychosis prediction in at-risk samples, however, mainly relies on study-specific sample means of neurocognitive tests, which unlike widely available general test norms are difficu...

journal_title：Schizophrenia bulletin

authors： Michel C,Ruhrmann S,Schimmelmann BG,Klosterkötter J,Schultze-Lutter F

更新日期：2014-11-01 00:00:00

abstract：:Psychotic experiences may be understood as altered information processing due to aberrant neural computations. A prominent example of such neural computations is the computation of prediction errors (PEs), which signal the difference between expected and experienced events. Among other areas showing PE coding, hippoca...

journal_title：Schizophrenia bulletin

authors： Heinz A,Murray GK,Schlagenhauf F,Sterzer P,Grace AA,Waltz JA

更新日期：2019-09-11 00:00:00

abstract：:Social cognitive deficits are associated with psychotic symptoms, but the nature of this association remains unknown. This study uses a genetically sensitive cross-trait cross-sibling design to investigate the nature of the overlap between both phenotypes. A sample of 1032 patients, 1017 of their healthy siblings, and...

journal_title：Schizophrenia bulletin

authors： Fett AK,Maat A,GROUP Investigators.

更新日期：2013-01-01 00:00:00

abstract：:Every year numerous reports on antipsychotic drug trials are being published in neuropsychiatric journals, adding new information to our knowledge in the field. The information however is often hard for the reader to interpret, sometimes contradictory to comparable available studies and leaves more questions open than...

journal_title：Schizophrenia bulletin

authors： Leucht S,Heres S,Hamann J,Kane JM

更新日期：2008-03-01 00:00:00

abstract：:The goals of the project Social Cognition and Functioning in Schizophrenia (SCAF) were to (1) identify the domains to target from social neuroscience for translation to clinical schizophrenia research, (2) identify the paradigms that represent these domains for which the neural substrates are well documented, (3) adap...

journal_title：Schizophrenia bulletin

authors： Green MF,Penn DL

更新日期：2013-11-01 00:00:00

abstract：:Although schizophrenia affects a number of brain regions and produces a range of clinical symptoms, we believe its origins lie at the level of single neurons and simple networks. Owing to this, as well as to its high degree of heritability, we hypothesize that schizophrenia is amenable to cell-based studies in vitro. ...

journal_title：Schizophrenia bulletin

authors： Tran NN,Ladran IG,Brennand KJ

更新日期：2013-01-01 00:00:00

abstract：:Empirical research related to ethical issues in clinical research has grown dramatically in recent years. However, little attention has been devoted to the ethical relevance of the findings from this research. In order to examine the value and limitations of ethics-related empirical research, we discuss 3 case studies...

journal_title：Schizophrenia bulletin

authors： Miller FG,Wendler D

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Neuropsychological deficits predate overt psychosis and overlap with the impairments in the established disease. However, to date, no single neurocognitive measure has shown sufficient power for a prognostic test. Thus, it remains to be determined whether multivariate neurocognitive pattern classification co...

journal_title：Schizophrenia bulletin

authors： Koutsouleris N,Davatzikos C,Bottlender R,Patschurek-Kliche K,Scheuerecker J,Decker P,Gaser C,Möller HJ,Meisenzahl EM

更新日期：2012-11-01 00:00:00

abstract：:Many previous observers have reported some qualitative similarities between the normal mental state of dreaming and the abnormal mental state of psychosis. Recent psychological, tomographic, electrophysiological, and neurochemical data appear to confirm the functional similarities between these 2 states. In this study...

journal_title：Schizophrenia bulletin

authors： Scarone S,Manzone ML,Gambini O,Kantzas I,Limosani I,D'Agostino A,Hobson JA

更新日期：2008-05-01 00:00:00

abstract：INTRODUCTION:Abnormalities in the neurophysiological measures P300 amplitude and latency constitute endophenotypes for psychosis. Disrupted-in-Schizophrenia-1 (DISC1) has been proposed as a promising susceptibility gene for schizophrenia, and a previous study has suggested that it is associated with P300 deficits in sc...

journal_title：Schizophrenia bulletin

authors： Shaikh M,Hall MH,Schulze K,Dutt A,Li K,Williams I,Walshe M,Constante M,Broome M,Picchioni M,Toulopoulou T,Collier D,Stahl D,Rijsdijk F,Powell J,Murray RM,Arranz M,Bramon E

更新日期：2013-01-01 00:00:00

abstract：:Clozapine can cause severe adverse effects yet it is associated with reduced mortality risk. We test the hypothesis this association is due to increased clinical monitoring and investigate risk of premature mortality from natural causes. We identified 14 754 individuals (879 deaths) with serious mental illness (SMI) i...

journal_title：Schizophrenia bulletin

authors： Hayes RD,Downs J,Chang CK,Jackson RG,Shetty H,Broadbent M,Hotopf M,Stewart R

更新日期：2015-05-01 00:00:00

abstract：:A selective review of the negative symptoms of schizophrenia is an appropriate article to result from the festschrift honoring William T. Carpenter Jr, as he has made substantial contributions in this area. This review assesses progress in 3 areas in which he has been an important investigator: the distinction between...

journal_title：Schizophrenia bulletin

authors： Kirkpatrick B

更新日期：2014-03-01 00:00:00

abstract：:Educating the public that mental illness is a brain disease is a popular strategy for combating mental illness stigma. Evidence suggests that while such an approach reduces blame for mental illness, it may unintentionally exacerbate other components of stigma, particularly the benevolence and dangerousness stigmas. Co...

journal_title：Schizophrenia bulletin

authors： Corrigan PW,Watson AC

更新日期：2004-01-01 00:00:00

abstract：:Although there is recent evidence that cells from the peripheral immune system can gain access to the central nervous system in certain conditions such as multiple sclerosis, their role has not been assessed in psychosis. Here, we aimed to explore whether blood cell count was associated with brain volume and/or clinic...

journal_title：Schizophrenia bulletin

authors： Núñez C,Stephan-Otto C,Usall J,Bioque M,Lobo A,González-Pinto A,Pina-Camacho L,Vieta E,Castro-Fornieles J,Rodriguez-Jimenez R,Butjosa A,Janssen J,Cabrera B,Parellada M,Bernardo M,PEPs group.

更新日期：2019-06-18 00:00:00

abstract：:We studied schizophrenia spectrum disorders in Chernobyl accident survivors by analyzing Chernobyl exclusion zone (EZ) archives (1986-1997) and by conducting a psychophysiological examination of 100 patients with acute radiation sickness (ARS) and 100 workers of the Chernobyl EZ who had worked as "liquidators-voluntee...

journal_title：Schizophrenia bulletin

authors： Loganovsky KN,Loganovskaja TK

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Insight into the neural mechanisms underlying the shared and disparate features of schizophrenia (SZ) and bipolar disorder (BD) is limited. The amygdala and prefrontal cortex (PFC) appear to have crucial roles in SZ and BD, yet abnormalities appear to manifest differently in the 2 disorders. METHODS:Eightee...

journal_title：Schizophrenia bulletin

authors： Liu H,Tang Y,Womer F,Fan G,Lu T,Driesen N,Ren L,Wang Y,He Y,Blumberg HP,Xu K,Wang F

更新日期：2014-03-01 00:00:00

abstract：:Psychobiological research in child psychiatry requires rigorous assessment of behavior and multiple perspectives on brain function through neurochemical, neuroendocrine, psychophysiological, and other advanced methods. The serious neuropsychiatric disorders of childhood, such as autism, attention deficit disorder, and...

journal_title：Schizophrenia bulletin

authors： Young JG,Cohen DJ,Shaywitz SE,Caparulo BK,Kavanagh ME,Hunt RD,Leckman JF,Anderson GM,Detlor J,Harcherik D,Shaywitz BA

更新日期：1982-01-01 00:00:00

abstract：:Phenomenological research suggests that pure manic and depressive states are less common than mixtures of the two and that the two poles of mood are characterized by opposite ways of experiencing time. In mania, the subjective experience of time is sped up and in depression it is slowed down, perhaps reflecting differ...

journal_title：Schizophrenia bulletin

authors： Ghaemi SN

更新日期：2007-01-01 00:00:00

abstract：:Disrupted thalamo-cortical connectivity is regarded as a core psychopathology in patients diagnosed with schizophrenia. However, whether the thalamo-cortical white matter connectivity is disrupted before the onset of psychosis is still unknown. To determine this gap in knowledge, the strength of thalamo-cortical white...

journal_title：Schizophrenia bulletin

authors： Cho KI,Shenton ME,Kubicki M,Jung WH,Lee TY,Yun JY,Kim SN,Kwon JS

更新日期：2016-05-01 00:00:00

abstract：:In addition to introducing the six articles joined by our thematic outlook, this article addresses the importance of subcortical structures as they may be related to information processing and the life experience of schizophrenic patients. This is a heuristic exercise aimed at bridging the conceptual gaps between clin...

journal_title：Schizophrenia bulletin

authors： Patterson T

更新日期：1987-01-01 00:00:00

abstract：OBJECTIVE:Both neurocognitive impairments and a history of childhood abuse are highly prevalent in patients with schizophrenia. Childhood trauma has been associated with memory impairment as well as hippocampal volume reduction in adult survivors. The aim of the following study was to examine the contribution of childh...

journal_title：Schizophrenia bulletin

authors： Shannon C,Douse K,McCusker C,Feeney L,Barrett S,Mulholland C

更新日期：2011-05-01 00:00:00

abstract：UNLABELLED:Early intervention is assumed to improve outcome in first-episode psychosis, but this has not been proven. OBJECTIVE:To study whether 1-year outcome will be better in a health care sector with early detection (ED) of psychosis compared with sectors with no early detection (no-ED). DESIGN:A quasi-experiment...

journal_title：Schizophrenia bulletin

authors： Larsen TK,Melle I,Auestad B,Friis S,Haahr U,Johannessen JO,Opjordsmoen S,Rund BR,Simonsen E,Vaglum P,McGlashan T

更新日期：2006-10-01 00:00:00

abstract：:In light of the large number of studies published since the 2004 update of Schizophrenia Patient Outcomes Research Team psychopharmacological treatment recommendations, we conducted an extensive literature review to determine whether the current psychopharmacological treatment recommendations required revision and whe...

journal_title：Schizophrenia bulletin

authors： Buchanan RW,Kreyenbuhl J,Kelly DL,Noel JM,Boggs DL,Fischer BA,Himelhoch S,Fang B,Peterson E,Aquino PR,Keller W,Schizophrenia Patient Outcomes Research Team (PORT).

更新日期：2010-01-01 00:00:00

abstract：Background:Motor abnormalities (MAs) of severe mental disorders have been traditionally neglected both in clinical practice and research, although they are an increasing focus of attention because of their clinical and neurobiological relevance. For historical reasons, most of the literature on MAs has been focused to ...

journal_title：Schizophrenia bulletin

authors： Peralta V,Cuesta MJ

更新日期：2017-09-01 00:00:00

abstract：:Migration is a major risk factor for schizophrenia but the neurochemical processes involved are unknown. One candidate mechanism is through elevations in striatal dopamine synthesis and release. The objective of this research was to determine whether striatal dopamine function is elevated in immigrants compared to non...

journal_title：Schizophrenia bulletin

authors： Egerton A,Howes OD,Houle S,McKenzie K,Valmaggia LR,Bagby MR,Tseng HH,Bloomfield MA,Kenk M,Bhattacharyya S,Suridjan I,Chaddock CA,Winton-Brown TT,Allen P,Rusjan P,Remington G,Meyer-Lindenberg A,McGuire PK,Mizrahi R

更新日期：2017-03-01 00:00:00

abstract：:With on exception, previous studies examining the familial relationship between schizotypal personality disorder (SPD) and schizophrenia have compared rates of SPD in relatives of probands with schizophrenia versus control probands. In the Roscommon Family Study, an epidemiologically based family study of major psychi...

journal_title：Schizophrenia bulletin

authors： Kendler KS,Walsh D

更新日期：1995-01-01 00:00:00

abstract：:Thirty psychiatric inpatients each rated their relationship with their auditory hallucination using the Structural Analysis of Social Behavior questionnaires which assess partnerships in terms of interpersonal focus, love-hate, and enmeshment-differentiation. Results showed that all subjects had integrated, interperso...

journal_title：Schizophrenia bulletin

authors： Benjamin LS

更新日期：1989-01-01 00:00:00