Abstract：
:Total serum LDH activity and isoenzyme distribution were studied in children with neuroblastoma at the time of hospital admission. The total LDH was determined in 26 cases, and 20 (77%) of them showed elevation of its activity. On the other hand, in 9 of these 26 cases, the isoenzyme distribution was determined along with the total LDH. All 9 cases, 4 of them with normal total LDH activity, showed an abnormal isoenzyme pattern with a percentage increase in the intermediate fractions (malignant pattern). The results suggest the usefulness of the determination of serum LDH isoenzymes as a screening procedure in children with malignant tumors including neuroblastoma.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Kinumaki H,Takeuchi H,Ohmi Kdoi
10.1007/BF00442638subject
Has Abstractpub_date
1976-09-01 00:00:00pages
83-7issue
2eissn
0340-6199issn
1432-1076journal_volume
123pub_type
杂志文章abstract：:By November 1994, 39 pregnancies had been completed in phenylketonuric mothers. Dietary control was post-conception in 6 and 2 of these offspring died of congenital heart disease and 1 other needed surgery for coarctation. There were no heart defects in the 34 offspring of the 33 pregnancies following preconception di...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/pl00014242
更新日期：1996-07-01 00:00:00
abstract：:An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02093730
更新日期：1991-04-01 00:00:00
abstract：:When a mother with tetralogy of Fallot has a conotruncal anomaly face, her child might have a 22q11.2 deletion and severe congenital heart disease. ...
journal_title：European journal of pediatrics
pub_type： 信件
doi：10.1007/s00431-001-0890-8
更新日期：2002-03-01 00:00:00
abstract：:Pediatric palliative care (PPC) focuses on children and adolescents with life-limiting diseases. It may be initiated at various points of the disease trajectory, if possible early enough to support living with the best possible quality of life despite a limited lifespan. From birth to adolescence, children with a broa...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s00431-012-1710-z
更新日期：2013-02-01 00:00:00
abstract：:Indomethacin treatment for 1 week monitored by drug level determinations was evaluated in 32 preterm infants with symptomatic patent ductus arteriosus (sPDA). Inter- and intra-individual indomethacin dispositions varied considerably with the need for marked dosage adjustments to maintain the drug level within the prop...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02343219
更新日期：1987-03-01 00:00:00
abstract：:We report on a 3-year-old boy presenting with left-sided eyelid myocloni due to an intracranial abscess harboring Haemophilus paraphrophilus. This is the first description of an intracranial infection with this pathogen in a child. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0560-6
更新日期：2008-06-01 00:00:00
abstract：:Paraneoplastic manifestations are signs and symptoms observed in patients with cancer, distant from the tumour or its metastases and not caused by invasion, obstruction or bulk mass. In children with cancer, paraneoplastic manifestations are rare and distinct from those observed in adults. Knowledge about paraneoplast...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/BF01972883
更新日期：1994-11-01 00:00:00
abstract：:From time to time, paediatricians are confronted with children who might suffer from a primary immunodeficiency disease. For practical purposes, these children can be divided into four main clinical categories: (1) a relatively large group of children with recurrent ear-nose and throat and lower respiratory tract infe...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/s004310100797
更新日期：2001-10-01 00:00:00
abstract：:This parallel randomized controlled trial was aimed to evaluate whether parameters as physical fitness, reaction times, self-perception and enjoyment levels, as well as parental and children perspectives, were affected by active video games in inactive and technologically preoccupied children. Data were collected in a...
journal_title：European journal of pediatrics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00431-019-03457-x
更新日期：2019-10-01 00:00:00
abstract：:A 7-year-old girl was admitted with a severe abdominal pain. Abdominal ultrasound and CT revealed a large splenic infarction, leading to the diagnosis of chronic myeloid leukemia. ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1675-y
更新日期：2012-07-01 00:00:00
abstract：UNLABELLED:Storage of human breast milk by freezing or refrigeration of milk with and without heating have been recommended. This can hardly be avoided because of the social circumstances of most mothers who are regularly separated from their infants because of work or schooling as well as the particular needs of some ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s004310000577
更新日期：2000-11-01 00:00:00
abstract：:The pre- and postnatal clinical, cytogenetic and embryological findings in a family suffering from trisomy 9p and spinal muscular atrophy are presented. The clinical picture of the "trisomy 9p" -syndrome is delineated. Concurrence of autosomal aberration and spinal muscular atrophy, probably of the Werdnig-Hoffmann ty...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00443119
更新日期：1977-08-23 00:00:00
abstract：:Term born infants are predisposed to human rhinovirus (HRV) lower respiratory tract infections (LRTI) by reduced neonatal lung function and genetic susceptibility. Our aim was to investigate whether prematurely born infants were similarly predisposed to HRV LRTIs or any other viral LRTIs. Infants born less than 36 wee...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-016-2780-0
更新日期：2016-12-01 00:00:00
abstract：UNLABELLED:Smith-Lemli-Opitz syndrome (SLOS), a multiple congenital anomaly with severe mental retardation, is caused by decreased activity of 7-dehydrocholesterol reductase. Fifteen Hungarian patients were diagnosed with SLOS on the basis of clinical symptoms, serum cholesterol, 7-dehydrocholesterol, and molecular gen...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1925-z
更新日期：2013-05-01 00:00:00
abstract：:There is far-reaching consent in the literature that public and consensual agreements on the basics of the different aspects of medical ethics are inalienable before the instigation of any innovative transplant procedure. In the case of a certain method and/or of an individual patient, however, the ultimate ethical ev...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF02125808
更新日期：1992-01-01 00:00:00
abstract：:Twin-to-twin transfusion (TTT) is a complication of monochorionic twins that may result in high mortality and morbidity. To better understand pathophysiology in TTT and the consequences for affected fetuses and neonates, we describe the clinical features of 19 consecutive pregnancies complicated by TTT over 5 years. T...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-002-1107-5
更新日期：2003-02-01 00:00:00
abstract：UNLABELLED:Human parechoviruses (HPeV) have been recently recognized as important viral agents in paediatric infections. The aims of this study were to investigate the HPeV infection prevalence in infants <1 month in Spain and, secondly, to analyse the clinical and epidemiological characteristics of the infected patien...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00431-015-2566-9
更新日期：2015-11-01 00:00:00
abstract：:Urinary recovery and serum determination of Paba were carried out in 48 control children (C) and 53 paediatric patients with cystic fibrosis (CF) divided into three classes by age. Ninety and 120 min after the ingestion of 15 mg/kg of BT-Paba and of a standard meal, serum Paba was determined. In the same subjects the ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00445804
更新日期：1984-12-01 00:00:00
abstract：:The description and analysis of the utilisation of medical services is of particular importance reflecting childhood morbidity. Therefore, our aim was to describe episode- and person-based rates of hospital admission in Germany, by focusing on the three most important clinically relevant categories, accident injuries,...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究
doi：10.1007/s00431-008-0859-y
更新日期：2009-08-01 00:00:00
abstract：:The aim of this study was to evaluate the feasibility of clinical application of infrared thermography (IRT) in the pediatric population and to identify pathological states that can be diagnosed as well as followed up using this non-invasive technique. In real time computer-assisted IRT, 483 examinations were performe...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0583-z
更新日期：2008-07-01 00:00:00
abstract：:Early identification of infants being at high risk to become obese at their later childhood or adolescence can be of vital importance in any obesity prevention initiative. The aim of the present study was to examine the utility and applicability of the "Childhood Obesity Risk Evaluation (CORE)" index as a screening to...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-016-2799-2
更新日期：2016-12-01 00:00:00
abstract：:Proper nutrition throughout childhood and adolescence is crucial for normal bone development. We investigated whether adherence to Christian Orthodox Church fasting is characterized by periodic avoidance of animal foods (including dairy products), since childhood affects stature or bone health in young adults. This cr...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-019-03542-1
更新日期：2020-04-01 00:00:00
abstract：:Adolescence obesity and depression are increasingly prevalent and are associated with various health complications. The aim of this study was to examine the association between weight status (normal weight, overweight, and obese) and depressive symptoms in adolescents and to explore the probable mediators, including o...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-012-1753-1
更新日期：2012-08-01 00:00:00
abstract：UNLABELLED:This study aimed to determine the population pharmacokinetics of doxapram in low-birth-weight (LBW) infants. A total of 92 serum concentration measurements that were obtained from 34 Japanese neonates were analyzed using nonlinear mixed-effect modeling (NONMEM). Estimates generated by NONMEM indicated that c...
journal_title：European journal of pediatrics
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00431-014-2416-1
更新日期：2015-04-01 00:00:00
abstract：:Hypoparathyroidism is one of the recognized causes of late-onset neonatal hypocalcemia. Maternal hypercalcemic hyperparathyroidism has been shown to suppress fetal parathyroid glands, causing transient neonatal hypoparathyroidism. We report two siblings (6 years apart) with transient hypoparathyroidism presented with ...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-007-0528-6
更新日期：2008-04-01 00:00:00
abstract：UNLABELLED:In order to determine the response to high-frequency oscillatory ventilation (HFOV), used as an "early rescue" therapy, in a cohort of paediatric patients with acute respiratory distress syndrome (ARDS), a prospective clinical study was performed in a tertiary care paediatric intensive care unit. Ten consecu...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-004-1544-4
更新日期：2005-01-01 00:00:00
abstract：:The etiology of asthma includes lifestyle factors. Breastfeeding and introduction of complementary foods have been suggested to affect asthma risk, but the scientific foundation is not solid. Children from the birth cohort All Babies In Southeast Sweden study were included (n = 9727). Breastfeeding duration and timing...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-018-03312-5
更新日期：2019-03-01 00:00:00
abstract：:We have investigated four patients from three unrelated families with typical clinical and biochemical features of "late-onset" multiple carboxylase deficiency. All patients suffered from biotinidase deficiency (plasma biotinidase activities 1.4%-3% of normal). Intestinal absorption of biotin, measured in three of the...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/BF00491919
更新日期：1985-05-01 00:00:00
abstract：UNLABELLED:In phenylketonuria, compliance and diet is a difficult issue; it is hard to quantify and is under-researched. It is influenced by many factors. Failure to consume prescribed quantity of protein substitute has been commonly reported and is probably affected by their acceptability, format and timing of adminis...
journal_title：European journal of pediatrics
pub_type： 杂志文章,评审
doi：10.1007/pl00014375
更新日期：2000-10-01 00:00:00
abstract：:Mutation in the orphan nuclear receptor DAX-1 gene causes X-linked adrenal hypoplasia congenita (AHC). Affected male children classically suffer a salt-losing crisis and adrenal insufficiency in their early infancy or, in some rare exceptions, with late-onset subtype. We report here a patient manifesting late-onset ad...
journal_title：European journal of pediatrics
pub_type： 杂志文章
doi：10.1007/s00431-008-0779-x
更新日期：2009-03-01 00:00:00
