Treatment of Behçet's disease.

Abstract:

:Behçet's disease is characterized with multifactorial etiopathogenesis and multiclinical pictures. The treatment of patients with Behçet's disease is based on the severity of illness, and the most appropriate management of Behçet's disease requires a multidisciplinary approach. Although various therapeutic modalities have been employed for Behçet's disease, treatment is far from satisfactory. Treatment of Behçet's disease includes local, systemic, or surgical therapies. Limited success has been found with colchicine, azathioprine, indomethacin, cyclophosphamide, chlorambucil, levamisole, transfer factor, fibrinolytic therapy, and systemic corticosteroid. New therapeutic approaches have been introduced for Behçet's disease using cyclosporine, thalidomide, interferon, acyclovir, high-dose corticosteroids or cyclophosphamide pulse therapy, and FK 506. We suggest that therapeutic agents should be selected after thorough evaluation of the immune state of each patient by using various tests and by determining any aggravating or provoking factors involved. In general, a combination-agent regimen is more effective than a single-agent regimen. Early diagnosis and proper treatment can inhibit or at lease slow the progress of the disease remarkably.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Bang D

doi

10.3349/ymj.1997.38.6.401

subject

Has Abstract

pub_date

1997-12-01 00:00:00

pages

401-10

issue

6

eissn

0513-5796

issn

1976-2437

journal_volume

38

pub_type

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