Silicon dioxide particles deposited in vessels and cartilage of the femoral head.

Abstract:

:Silicosis had been considered for decades as an illness with manifestations of lung fibrosis due to inhalation of overconcentrated SiO₂ dust. To the best of our knowledge, studies have yet to report SiO₂ deposits in any other tissues and organs. In the present case, while performing bilateral artificial total hip arthroplasty for one patient, we found that the articular cartilage of the bilateral femoral head was black. Therefore, specimens thereof were sent for pathological examination. Pathological examination (immunohistochemistry) and polarized light microscopy revealed the presence of considerable brown, acicular, rhombic, and crumb-like crystals. The crystals were mainly composed of SiO₂. SiO₂ could deposit in vessels and femoral head cartilage via blood circulation.

journal_name

Yonsei Med J

journal_title

Yonsei medical journal

authors

Xu M,Qing M,Peng D

doi

10.3349/ymj.2014.55.5.1447

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

1447-9

issue

5

eissn

0513-5796

issn

1976-2437

pii

2014091447

journal_volume

55

pub_type

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