Abstract：
:The humoral and cell mediated immune response was investigated in 90 patients suffering from chronic posttraumatic osteomyelitis. In 10-20% of the patients the serum IgG and IgM was increased, in 5-10% the levels were decreased. The values were compared with those of a control group of 35 normal healthy volunteers. Of 55 patients with staphylococcal infection only 25 had a positive antistaphylolysin titer. Eleven out of 25 patients with staphylococcal osteomyelitis showed a positive in vitro lymphocyte transformation after stimulation with alpha-staphylolysin (mean transformation rate 5.4 equal to or less than 0.9). The phytohemagglutinin and the pokeweed-mitogen response were normal. A comparison of the immunological reactivity of the patients and the clinical severity of the disease showed that patients with established delayed-type hypersensitivity phenomena suffered a significantly worse clinical course of the disease.
journal_name
Infectionjournal_title
Infectionauthors
Ring J,Seifert J,Zinn K,Stickl H,Probst J,Brendel Wdoi
10.1007/BF01638722subject
Has Abstractpub_date
1976-01-01 00:00:00pages
84-9issue
2eissn
0300-8126issn
1439-0973journal_volume
4pub_type
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