Computer-aided detection of clustered microcalcifications in digitized mammograms.

Abstract:

RATIONALE AND OBJECTIVES:We investigated a computer-aided detection (CAD) scheme for clustered microcalcifications in digitized mammograms. METHODS:A multistage CAD scheme was developed and tested. To increase sensitivity, the scheme uses a Gaussian band-pass filter and nonlinear threshold. A multistage local minimum searching routine and a multilayer topographic feature analysis are used to reduce the false-positive detection rate. One hundred ten digitized mammograms were used in this preliminary test, with 55 images containing one or two verified microcalcification clusters. RESULTS:The CAD scheme achieved 100% sensitivity and had an average false-positive detection rate of 0.18 per image. CONCLUSION:The CAD scheme performs as well as many published schemes and has some unique advantages to further improve detection sensitivity and specificity of future CAD schemes.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Zheng B,Chang YH,Staiger M,Good W,Gur D

doi

10.1016/s1076-6332(05)80431-3

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

655-62

issue

8

eissn

1076-6332

issn

1878-4046

journal_volume

2

pub_type

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