Prospective Multiparametric Magnetic Resonance Monitoring of Changes in Lesions of Hyaline Cartilage of the Knee Joint After Treatment by Microfractures and Implantation of Biological Collagen Type I Matrix Implants .

Abstract:

RATIONALE AND OBJECTIVES:This study's aims were to depict changes in cartilage quality after surgical intervention using magnetic resonance (MR) examination and in content of glycosaminoglycans chains (GAGs) after two types of surgeries - chondral defect treatment by microfractures and scaffold implantation in combination with microfractures. MATERIALS AND METHODS:Twenty-five patients were studied: 14 with implants, 11 with microfractures. MR examination was made before surgery and 6, 12, and 18 months thereafter. Qualitative changes in cartilage were observed by means of delayed gadolinium enhanced magnetic resonance imaging of cartilage sequence using Gd-DTPA2- and Gd-DOTA. In each examination, GAGs content was determined at three locations: the defect, its surroundings, and a non-load-bearing reference area. RESULTS:Measured indices showed no statistically significant differences in changes within the defect area when comparing the two treatment types at individual time points of 6, 12, and 18 months. In the case of microfracture treatment, more substantial decrease in GAGs concentration occurred at month 6, whereas the greatest decline occurred at month 12 when using an implant. Change in GAGs content and decline in cartilage quality were substantial also in the reference area and close surroundings. CONCLUSIONS:Hyaline cartilage behaves as a unified whole, and change in GAGs content was marked also in locations with no morphological damage. Over the monitored period, no statistically significant difference between treatment types was noted as measured by GAGs content in the defect or its close surroundings. dGEMRIC is suitable for monitoring cartilage quality even if use of Gd-DTPA2- is not possible, because comparable results were achieved using Gd-DOTA.

journal_name

Acad Radiol

journal_title

Academic radiology

authors

Šprláková-Puková A,Štouračová A,Repko M,Koriťáková E,Tintěra J,Dostál M,Otaševič T

doi

10.1016/j.acra.2020.05.030

subject

Has Abstract

pub_date

2020-06-30 00:00:00

eissn

1076-6332

issn

1878-4046

pii

S1076-6332(20)30337-8

pub_type

杂志文章
  • Subtraction CT angiography of the lower extremities: single volume subtraction versus multi-segmented volume subtraction.

    abstract:RATIONALE AND OBJECTIVES:To validate the hypothesis that a multisegmented approach during subtraction computed tomography (CT) angiography of the lower extremities can improve bone removal efficiency by suppressing regional motion. MATERIALS AND METHODS:The institutional review board of our hospital approved this retr...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.01.024

    authors: Lee IJ,Chung JW,Hong H,Yin YH,Kim S,Park EA,Lee W

    更新日期:2011-07-01 00:00:00

  • Imaging Features of Coronavirus disease 2019 (COVID-19): Evaluation on Thin-Section CT.

    abstract:RATIONALE AND OBJECTIVES:To retrospectively analyze the chest imaging findings in patients with coronavirus disease 2019 (COVID-19) on thin-section CT. MATERIALS AND METHODS:Fifty-three patients with confirmed COVID-19 infection underwent thin-section CT examination. Two chest radiologists independently evaluated the ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.03.002

    authors: Guan CS,Lv ZB,Yan S,Du YN,Chen H,Wei LG,Xie RM,Chen BD

    更新日期:2020-05-01 00:00:00

  • Fellowship directors' perceptions of the 2005 NRMP Radiology Fellowship Match.

    abstract:RATIONALE AND OBJECTIVES:The aim of the study is to gauge radiology fellowship directors' experiences with the fellowship application process and perceptions of the National Resident Matching Program Radiology Fellowship Match, as well as compare these perceptions with those of senior residents. METHODS AND MATERIALS:...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2005.09.085

    authors: Shetty SK,Resnik CS

    更新日期:2006-01-01 00:00:00

  • Mesoscopic fluorescence tomography of a photosensitizer (HPPH) 3D biodistribution in skin cancer.

    abstract:RATIONALE AND OBJECTIVES:Photodynamic therapy (PDT) is a promising strategy for treating cancer. PDT involves three components: a photosensitizer (PS) drug, a specific wavelength of drug-activating light, and oxygen. A challenge in PDT is the unknown biodistribution of the PS in the target tissue. In this preliminary s...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2013.11.009

    authors: Ozturk MS,Rohrbach D,Sunar U,Intes X

    更新日期:2014-02-01 00:00:00

  • Influence of using manual or automatic breast density information in a mass detection CAD system.

    abstract:RATIONALE AND OBJECTIVES:The goal of this article is to analyze and compare the performance of a developed mass computer-aided detection (CAD) system that takes breast density information into account when using manual or automatic breast density annotations in the training step. The advantages of considering this brea...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2010.04.013

    authors: Oliver A,Lladó X,Freixenet J,Martí R,Pérez E,Pont J,Zwiggelaar R

    更新日期:2010-07-01 00:00:00

  • Quantitative Characterization of the Prostatic Urethra Using MRI: Implications for Lower Urinary Tract Symptoms in Patients with Benign Prostatic Hyperplasia.

    abstract:INTRODUCTION:The aim of this study was to perform a quantitative assessment of the prostate anatomy with a focus on the relation of prostatic urethral anatomic variation to urinary symptoms. METHODS:This retrospective study involved patients undergoing magnetic resonance imaging for prostate cancer who were also asses...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.03.017

    authors: Sanford TH,Harmon SA,Kesani D,Gurram S,Gupta N,Mehralivand S,Sackett J,Wiener S,Wood BJ,Xu S,Pinto PA,Choyke PL,Turkbey B

    更新日期:2020-04-16 00:00:00

  • Use of 3D Printed Models to Create Molds for Shaping Implants for Surgical Repair of Orbital Fractures.

    abstract:RATIONALE AND OBJECTIVES:Surgical repair of an isolated orbital fracture requires anatomically accurate implant shape and placement. We describe a three-dimensional (3D) printing technique to customize the shape of commercially available absorbable implants. MATERIALS AND METHODS:We reviewed our early experience with ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.06.023

    authors: Weadock WJ,Heisel CJ,Kahana A,Kim J

    更新日期:2020-04-01 00:00:00

  • Breast Imaging Boot Camp Meets Milestones 2.0: A Match Made in Clinic.

    abstract:RATIONALE AND OBJECTIVES:Designed to provide broad-based training in all aspects of imaging, the diagnostic radiology residency program must provide educational experiences that not only provide technical training, but also meet accreditation standards. With the breadth of material to cover during training, carefully o...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2020.12.022

    authors: Jordan SG,Lee SS,Rivers LM,Schwartz CJ,Benefield T,Beck Dallaghan GL

    更新日期:2021-01-21 00:00:00

  • Videomanometry of the pharynx in dysphagic patients with a posterior cricopharyngeal indentation.

    abstract:RATIONALE AND OBJECTIVES:Patients with a posterior indentation in the pharyngoesophageal segment (PES) are generally considered to have an abnormality of the cricopharyngeal muscle (CPM). In this study we determined the actual width of the PES and the pressure circumstances during swallowing within the pharynx and PES ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80123-0

    authors: Olsson R,Ekberg O

    更新日期:1995-07-01 00:00:00

  • Evaluation of analgesic effect of equimolar mixture of oxygen and nitrous oxide inhalation during percutaneous biopsy of focal liver lesions: a double-blind randomized study.

    abstract:RATIONALE AND OBJECTIVES:Percutaneous liver biopsy for tumors performed under local anesthesia is still a painful procedure. The aim of this study was to evaluate the patient's reaction and the analgesic efficacy and safety of an equimolar mixture of oxygen and nitrous oxide (EMONO) inhalation. MATERIALS AND METHODS:A...

    journal_title:Academic radiology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.acra.2011.01.025

    authors: Meskine N,Vullierme MP,Zappa M,d'Assignies G,Sibert A,Vilgrain V

    更新日期:2011-07-01 00:00:00

  • Characterization of brain plasticity in schizophrenia using template deformation.

    abstract:RATIONALE AND OBJECTIVE:Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains. MATERIALS AND METHODS:We used a set of skull-stripped brains from an im...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2004.06.009

    authors: Dubb A,Xie Z,Gur R,Gur R,Gee J

    更新日期:2005-01-01 00:00:00

  • An ellipsoidal shell model for volume estimation of the right ventricle from magnetic resonance images.

    abstract:RATIONALE AND OBJECTIVES:I developed a volume estimation technique for the crescentic volume of the right ventricle (RV) of the heart. A geometric model was desired to avoid the lengthy data collection and reduction required by Simpson's rule. METHODS:An ellipsoidal shell model was developed that requires only simple ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(12)80006-7

    authors: Denslow S

    更新日期:1994-12-01 00:00:00

  • A theoretical model using mechanical principles to quantify the physical principles of balloon dilatation.

    abstract:RATIONALE AND OBJECTIVES:Balloon dilatation is a mechanical form of controlled injury used to alleviate vascular stenoses. Several factors influence successful angioplasty. Few mechanical models exist to illustrate the physical principles of balloon dilatation. METHODS:We used mechanical analysis of membrane stresses,...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(05)80340-x

    authors: Kinney TB,Lee MJ,Mueller PR,Waltman AC

    更新日期:1995-05-01 00:00:00

  • Three-dimensional volume rendering of fetal MR images for the diagnosis of congenital cystic adenomatoid malformation.

    abstract:RATIONALE AND OBJECTIVES:Great expertise is necessary to mentally compile a series of individual two-dimensional image sections into a three-dimensional (3D) composite view that can aid in differential diagnosis. The purpose of this study was to test 3D volume-rendering techniques for differentiating congenital cystic ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(03)80108-3

    authors: Hata N,Wada T,Chiba T,Tsutsumi Y,Okada Y,Dohi T

    更新日期:2003-03-01 00:00:00

  • Nonclinical factors associated with primary care physicians' ordering patterns of magnetic resonance imaging/computed tomography for headache.

    abstract:RATIONALE AND OBJECTIVES:The purpose of ordering an imaging test for headache, which is one of the most common reasons for patient consultation with a primary care physician (PCP), include medical indications as well as patient anxiety and medico-legal concerns. The impact of nonclinical factors on PCPs' ordering patte...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2004.03.050

    authors: Couchman GR,Forjuoh SN,Rajab MH,Phillips CD,Yu J

    更新日期:2004-07-01 00:00:00

  • Preoperative Prediction of Axillary Lymph Node Metastasis in Breast Carcinoma Using Radiomics Features Based on the Fat-Suppressed T2 Sequence.

    abstract:RATIONALE AND OBJECTIVES:To investigate the value of radiomics method based on the fat-suppressed T2 sequence for preoperative predicting axillary lymph node (ALN) metastasis in breast carcinoma. MATERIALS AND METHODS:The data of 329 invasive breast cancer patients were divided into the primary cohort (n = 269) and va...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.11.004

    authors: Tan H,Gan F,Wu Y,Zhou J,Tian J,Lin Y,Wang M

    更新日期:2020-09-01 00:00:00

  • Liver perfusion imaging in patients with primary and metastatic liver malignancy: prospective comparison between 99mTc-MAA spect and dynamic CT perfusion.

    abstract:RATIONALE AND OBJECTIVES:To prospectively analyze the correlation between parameters of liver perfusion from technetium99m-macroaggregates of albumin (99mTc-MAA) single photon emission computed tomography (SPECT) with those obtained from dynamic CT perfusion in patients with primary or metastatic liver malignancy. MAT...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2011.12.015

    authors: Reiner CS,Goetti R,Burger IA,Fischer MA,Frauenfelder T,Knuth A,Pfammatter T,Schaefer N,Alkadhi H

    更新日期:2012-05-01 00:00:00

  • A text-to-speech converter for radiology journal articles.

    abstract::Radiology articles are primarily designed to be read on paper or a screen. Audio versions let users hear this material during activities when reading is not practical. Currently, there are relatively few radiology materials in audio format. However, inexpensive text-to-speech software can easily produce spoken-word ve...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2010.06.020

    authors: Richardson ML

    更新日期:2010-12-01 00:00:00

  • Dissecting Costs of CT Study: Application of TDABC (Time-driven Activity-based Costing) in a Tertiary Academic Center.

    abstract:RATIONALE AND OBJECTIVES:The lack of understanding of the real costs (not charge) of delivering healthcare services poses tremendous challenges in the containment of healthcare costs. In this study, we applied an established cost accounting method, the time-driven activity-based costing (TDABC), to assess the costs of ...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2016.11.001

    authors: Anzai Y,Heilbrun ME,Haas D,Boi L,Moshre K,Minoshima S,Kaplan R,Lee VS

    更新日期:2017-02-01 00:00:00

  • Ex Vivo Study of Artifacts Caused by Breast Tissue Markers with Different 1.5 Tesla and 3 Tesla MRI Scanners - A Bicentric Study.

    abstract:RATIONALE AND OBJECTIVES:The purpose of our study was to evaluate magnetic resonance (MR) artifacts related to breast tissue markers in breast imaging procedures. MATERIALS AND METHODS:In this bicentric prospective ex vivo study 10 different commercially available markers were measured in self-made breast phantoms. Br...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.12.006

    authors: Puesken M,Unterberg-Buchwald C,Rhiem K,Große Hokamp N,Maintz D,Lotz J,Wienbeck S

    更新日期:2021-01-01 00:00:00

  • Abbreviated screening protocol for breast MRI: a feasibility study.

    abstract:RATIONALE AND OBJECTIVES:To compare the performance of two shortened breast magnetic resonance imaging (MRI) protocols to a standard MRI protocol for breast cancer screening. MATERIALS AND METHODS:In this Health Insurance Portability and Accountability Act compliant, institutional review board-approved pilot study, th...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2015.06.004

    authors: Grimm LJ,Soo MS,Yoon S,Kim C,Ghate SV,Johnson KS

    更新日期:2015-09-01 00:00:00

  • Clinical Applications of DSC-MRI Parameters Assess Angiogenesis and Differentiate Malignant From Benign Soft Tissue Tumors in Limbs.

    abstract:OBJECTIVE:To investigate the correlation between dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) parameters and angiogenesis and to explore prospectively the feasibility of using DSC-MRI to differentiate malignant from benign soft tissue tumors (STTs) in limbs. METHODS:This prospective study inclu...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2019.04.023

    authors: Bian Y,Jin P,Wang Y,Wei X,Qiang Y,Niu G,Jin G,Yang J

    更新日期:2020-03-01 00:00:00

  • Teaching and Assessing Professionalism in Radiology: Resources and Scholarly Opportunities to Contribute to Required Expectations.

    abstract::Teaching and assessing trainees' professionalism now represents an explicit expectation for Accreditation Council Graduate Medical Education-accredited radiology programs. Challenges to meeting this expectation include variability in defining the construct of professionalism; limits of traditional teaching and assessm...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2018.01.008

    authors: Kelly AM,Mullan PB

    更新日期:2018-05-01 00:00:00

  • Ultrasound biomicroscopy for the detection of early osteoarthritis in an animal model.

    abstract:RATIONALE AND OBJECTIVES:Osteoarthritis (OA) is a common disease, and early diagnosis is essential for preventing further cartilage destruction and decreasing severe complications. Ultrasound biomicroscopy (UBM) is sensitive for detecting minute lesions in tissue because of its higher resolution, but its B-mode charact...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2010.09.011

    authors: Wang Y,Guo Y,Zhang L,Niu H,Xu M,Zhao B,Wan W

    更新日期:2011-02-01 00:00:00

  • Postoperative CT of the Mandible Following Trauma: Review of Normal Appearances and Common Complications.

    abstract:RATIONALE AND OBJECTIVES:Surgeons aim to restore occlusion and jaw function to baseline status for patients with mandibular fractures using either closed treatment or reduction and fixation. MATERIALS AND METHODS:Occlusion is defined as the relationship between the maxillary and mandibular teeth as they approach each ...

    journal_title:Academic radiology

    pub_type: 杂志文章,评审

    doi:10.1016/j.acra.2018.06.009

    authors: Reiter MJ,Schwope RB,Theler JM

    更新日期:2019-05-01 00:00:00

  • Radiology faculty evaluation: bi-institutional implementation of an experimental appraisal instrument.

    abstract:RATIONALE AND OBJECTIVES:The authors evaluated the reliability and validity of an experimental radiology faculty appraisal instrument. MATERIALS AND METHODS:Residents from the University of Wisconsin (UW) and Indiana University (IU) were asked to use a previously developed behaviorally based, 53-item experimental facu...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/s1076-6332(98)80266-3

    authors: Collins J,Albanese MA,Scanlan KA,Propeck PA,Jackson VP

    更新日期:1998-11-01 00:00:00

  • Healthy aging: an automatic analysis of global and regional morphological alterations of human brain.

    abstract:RATIONALE AND OBJECTIVES:Morphologic changes of the human brain during healthy aging provide useful reference knowledge for age-related brain disorders. The aim of this study was to explore age-related global and regional morphological changes of healthy adult brains. MATERIALS AND METHODS:T1-weighted magnetic resonan...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2012.03.006

    authors: Long X,Liao W,Jiang C,Liang D,Qiu B,Zhang L

    更新日期:2012-07-01 00:00:00

  • Loss of anteroposterior intralobar attenuation gradient of the lung: Correlation with pulmonary function.

    abstract:RATIONALE AND OBJECTIVES:Since the initial description of an intralobar attenuation gradient by Webb et al, it has been suggested that departure from the intralobar attenuation gradient could indicate early lung diseases. However, its significance has not been determined in detail. We aimed to quantify the anteroposter...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2005.10.025

    authors: Nishino M,Roberts DH,Sitek A,Raptopoulos V,Boiselle PM,Hatabu H

    更新日期:2006-05-01 00:00:00

  • Pulmonary functional magnetic resonance imaging: asthma temporal-spatial maps.

    abstract:RATIONALE AND OBJECTIVES:Hyperpolarized (3)He magnetic resonance imaging (MRI) previously revealed the temporal and spatial heterogeneity of ventilation defects in asthmatics, but these findings have not been used in treatment studies or to guide personalized therapy. Our objective was to exploit the temporal and spati...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2014.08.002

    authors: Svenningsen S,Guo F,Kirby M,Choy S,Wheatley A,McCormack DG,Parraga G

    更新日期:2014-11-01 00:00:00

  • Breast DCE-MRI: influence of postcontrast timing on automated lesion kinetics assessments and discrimination of benign and malignant lesions.

    abstract:RATIONALE AND OBJECTIVES:Breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) scanning protocols vary widely. The purpose of this study was to determine the effects of postcontrast timing on delayed-phase lesion kinetics assessment and ability to discriminate malignant from benign lesions. MATERIALS A...

    journal_title:Academic radiology

    pub_type: 杂志文章

    doi:10.1016/j.acra.2014.04.013

    authors: Partridge SC,Stone KM,Strigel RM,DeMartini WB,Peacock S,Lehman CD

    更新日期:2014-09-01 00:00:00