Abstract:
RATIONALE AND OBJECTIVES:SYNTAX score is a useful metric determined at the time of invasive coronary angiography (ICA) to assess the complexity of coronary artery disease, and improves prediction of complications at the time of percutaneous complex intervention (PCI). We aimed to determine whether SYNTAX score can be reliably determined from coronary computed tomography angiography (CCTA) and whether a CCTA-derived SYNTAX score can predict complex PCI. MATERIALS AND METHODS:SYNTAX scores were calculated on per-patient, per-vessel, and per-segment basis in 154 consecutive patients who underwent CCTA and ICA. PCI complexity in 113 patients who underwent intervention was defined by total fluoroscopy time and contrast volume. RESULTS:Compared to ICA, CCTA detected 285 of 302 (94%) obstructive lesions in 230 vessels, for which PCI was performed for 154 lesions in 131 vessels. Overall, on a per-patient basis, ICA-derived SYNTAX score was lower in comparison to CCTA-derived score (10.2 ± 8.0 vs 10.9 ± 8.3, P = 0.001). As compared to lesions in the lowest CCTA-derived segmental SYNTAX tertile, lesions in the highest tertile required longer fluoroscopy time (17.5 ± 12 min vs 11.5 ± 7.9 min, P = 0.01) and greater contrast volume (215.4 ± 125.5 mL vs 144.3 ± 49 mL, P = 0.02). CONCLUSION:SYNTAX scores derived from CCTA are concordant with those derived from ICA and correspond with complex PCI.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Shalev A,Nakazato R,Arsanjani R,Nakanishi R,Park HB,Otaki Y,Cheng VY,Gransar H,LaBounty TM,Hayes SW,Berman DS,Min JKdoi
10.1016/j.acra.2016.07.003subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1384-1392issue
11eissn
1076-6332issn
1878-4046pii
S1076-6332(16)30159-3journal_volume
23pub_type
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