Polymyalgia rheumatica and chronic lymphatic leukaemia.

Abstract:

:A patient with polymyalgia rheumatica (PMR) is reported in whom, at the time of diagnosis, the number of lymphocytes in peripheral blood and bone marrow was normal. Lymphocytic infiltration typical of PMR was detected in renal and muscle biopsy specimens, and a liver fine-needle aspirate contained an abnormal lymphocytic infiltration, probably leukaemic. The number of lymphocytes gradually increased in bone marrow and peripheral blood until, almost 5 years after PMR had been diagnosed, a typical picture of chronic lymphatic leukaemia (CLL) was observable. The significance of the reported combination is discussed. The possibility is pointed out that a CLL in progress must be suspected when persistent lymphocytosis occurs in a patient with typical PMR, even if initially the response to treatment with corticosteroids suggests that PMR is the sole disorder.

journal_name

Scand J Rheumatol

authors

von Knorring J,Selroos O

doi

10.3109/03009747709095438

subject

Has Abstract

pub_date

1977-01-01 00:00:00

pages

145-7

issue

3

eissn

0300-9742

issn

1502-7732

journal_volume

6

pub_type

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