CPH 82 (Reumacon) in refractory inflammatory arthritis.

Abstract:

:In this retrospective analysis of the DMARD CPH 82 in 44 Icelandic patients with severe refractory arthritis, clinical tolerance was good and serious side effects absent, although the majority were using the drug in combination with other DMARDS. Side effects leading to discontinuation were seen in 16% and the three year drug-survival was 51%.

journal_name

Scand J Rheumatol

authors

Gudmundsdóttir ES,Jónsson H

doi

10.1080/030097400447723

keywords:

subject

Has Abstract

pub_date

2000-01-01 00:00:00

pages

323-5

issue

5

eissn

0300-9742

issn

1502-7732

journal_volume

29

pub_type

临床试验,杂志文章
  • Osmium deposits detected by x-ray after synoviorthesis of the knee.

    abstract::A study of 113 knees of 72 patients treated with intra-articular injection of osmic acid for chronic exudative synovitis caused by various rheumatic diseases is reported. Certain cases presented abnormal radiological opacities, statistically more frequent after the injection of 200 mg than after 100 mg of osmic acid (...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:

    authors: Boussina I,Lagier R,Ott H,Fallet GH

    更新日期:1976-01-01 00:00:00

  • Symptomatology and diagnosis in connective tissue disease. II. Evaluations and follow-up examinations in consequence of a speckled antinuclear immunofluorescence pattern.

    abstract::Antibodies to soluble ribonucleoprotein (sRNP) are by definition a prerequisite for the diagnosis mixed connective tissue disease (MCTD). They are also found in 30--40% of other rheumatic conditions with a high titred speckled IFL reaction. The same is true for the most characteristic clinical features of MCTD, viz. R...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009747809095661

    authors: Jonsson J,Norberg R

    更新日期:1978-01-01 00:00:00

  • Clinical outcome after one year following samarium-153 particulate hydroxyapatite radiation synovectomy.

    abstract::The clinical outcome and tolerability following treatment with samarium-153 particulate hydroxyapatite was evaluated in patients with persistent rheumatoid knee synovitis. The clinical review of 18 patients treated with intra-articular samarium-153 particulate hydroxyapatite combined with triamcinolone hexacetonide wh...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749609065647

    authors: Clunie G,Lui D,Cullum I,Ell PJ,Edwards JC

    更新日期:1996-01-01 00:00:00

  • The effect of multimeric adiponectin isoforms and leptin on the function of rheumatoid fibroblast-like synoviocytes.

    abstract:OBJECTIVES:To evaluate the effects of physiologically relevant concentrations of multimeric adiponectin isoforms and leptin on the function of fibroblast-like synoviocytes (FLS) from patients with rheumatoid arthritis (RA). METHOD:FLS, isolated from the synovial tissue of 21 RA patients, were stimulated for 24 h with ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1025833

    authors: Kontny E,Janicka I,Skalska U,Maśliński W

    更新日期:2015-01-01 00:00:00

  • Sudden death and Wegener's granulomatosis of the pituitary.

    abstract::Involvement of brain parenchyma or meninges in ANCA-associated small-vessel vasculitis such as Wegener's granulomatosis (WG) is not uncommon. In contrast, involvement of the pituitary is exceedingly rare with only a few cases reported so far. The diagnosis is usually made on the basis of imaging techniques and abnorma...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097400750041433

    authors: Woywodt A,Knoblauch H,Kettritz R,Schneider W,Göbel U

    更新日期:2000-01-01 00:00:00

  • Anti-CD20 therapy of treatment-resistant Wegener's granulomatosis: favourable but temporary response.

    abstract::Rituximab is a genetically engineered chimeric monoclonal immunoglobulin (Ig)G1 antibody. It binds the CD20 trans-membrane surface antigen expressed by mature B cells but not by antibody secreting plasma cells, and removes the cells by activating complement, inducing cell-mediated lysis, and by apoptosis. Mainly used ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/02813430510015269

    authors: Omdal R,Wildhagen K,Hansen T,Gunnarsson R,Kristoffersen G

    更新日期:2005-05-01 00:00:00

  • Severe and prolonged febrile myalgia in familial Mediterranean fever.

    abstract::Familial Mediterranean fever (FMF) is characterized by recurrent attacks of fever and serositis. Typical attacks of FMF last 3 to 5 days. Fever and myalgia are not always improved by colchicine therapy and sometimes require steroid therapy. We present two cases of severe prolonged febrile myalgia where steroid therapy...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097400447615

    authors: Odabas AR,Cetinkaya R,Selcuk Y,Kaya H

    更新日期:2000-01-01 00:00:00

  • The use of anthropometric measures in the prediction of incident gout: results from a Swedish community-based cohort study.

    abstract::Objectives: To study associations between different anthropometric measures and incident gout, and to find the best predictive measure. Method: We used the baseline investigation from the Malmö Diet and Cancer study, excluding cases of prevalent gout (n = 28 081). Cox regression for each anthropometric measurement was...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2019.1583368

    authors: Wändell P,Andreasson A,Hagström H,Kapetanovic MC,Carlsson AC

    更新日期:2019-07-01 00:00:00

  • Bilateral ankylosis of temporomandibular joint secondary to ankylosing spondylitis in a male Chinese.

    abstract::A case of bilateral temporomandibular joint (TMJ) ankylosis in a Chinese male patient with ankylosing spondylitis is presented. A review of the literature emphasizes the rarity of this arthro-pathology in ankylosing spondylitis. The importance in the recognition of this complication by clinical examination supplemente...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749709115833

    authors: Chow TK,Ng WL,Tam CK,Kung N

    更新日期:1997-01-01 00:00:00

  • The number needed to treat for adalimumab, etanercept, and infliximab based on ACR50 response in three randomized controlled trials on established rheumatoid arthritis: a systematic literature review.

    abstract:OBJECTIVE:To compare the efficacy of adalimumab, etanercept, and infliximab in patients with established rheumatoid arthritis (RA) taking concomitant methotrexate (MTX) by calculating the number needed to treat (NNT) using three different methods. METHODS:A systematic literature search of the Cochrane Library, MEDLINE...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章,评审

    doi:10.1080/03009740701607067

    authors: Kristensen LE,Christensen R,Bliddal H,Geborek P,Danneskiold-Samsøe B,Saxne T

    更新日期:2007-11-01 00:00:00

  • Systemic vasculitis associated with Fasciola hepatica infection.

    abstract::We report the case of a 50-year-old man who presented with systemic vasculitis associated with Fasciola hepatica infection. The patient presented with severe skin, kidney, spleen, ophthalmic, and neurological compromise. An immunological examination for primary vasculitis was negative and other infections were discoun...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740500303231

    authors: Llanos C,Soto L,Sabugo F,Gallegos I,Valenzuela O,Verdaguer J,Cuchacovich M

    更新日期:2006-03-01 00:00:00

  • Differences associated with age at onset in early systemic sclerosis patients: a report from the EULAR Scleroderma Trials and Research Group (EUSTAR) database.

    abstract:OBJECTIVE:The aim of this study was to analyse differences in clinical presentation in patients with early (< 3 years' duration) systemic sclerosis (SSc), comparing three age groups according to disease subsets. METHOD:Cross-sectional analysis of the prospective EULAR Scleroderma Trials and Research database (EUSTAR) ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章,多中心研究

    doi:10.1080/03009742.2018.1459830

    authors: Carreira PE,Carmona L,Joven BE,Loza E,Andréu JL,Riemekasten G,Vettori S,Balbir-Gurman A,Airò P,Walker U,Damjanov N,Matucci-Cerinic M,Ananieva LP,Rednic S,Czirják L,Distler O,Farge D,Hesselstrand R,Corrado A,Caramasc

    更新日期:2019-01-01 00:00:00

  • Pathways of destruction in metacarpal and metatarsal joints of patients with rheumatoid arthritis.

    abstract::219 metatarsal (MTP) and 69 metacarpal (MCP) capitulae obtained during surgery from patients with definite rheumatoid arthritis (RA) were histologically evaluated. This evaluation, focussing on primary pathways of joint destruction by tumor-like proliferated synovial cell masses revealed 3 pathways of aggression: Path...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009749209095055

    authors: Fassbender HG,Seibel M,Hebert T

    更新日期:1992-01-01 00:00:00

  • An assessment of the new "SCORE" index as a predictor of osteoporosis in women.

    abstract:BACKGROUND:The study was done to determine whether the new SCORE (Simple Calculated Osteoporosis Risk Estimation) index might reduce the utilization of bone mineral density (BMD) measurement. METHODS:989 consecutive patients who were referred by a range of physicians for BMD assessments at one of two clinics had a SCO...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097401750065300

    authors: Russell AS,Morrison RT

    更新日期:2001-01-01 00:00:00

  • The effect of ibuprofen on the thickening, stiffening and development of degenerative changes in the rabbit knee following immobilization.

    abstract::The right knee of adult rabbits was immobilized in extension for 5 weeks. The rabbits were then allowed to move freely for 8 weeks. Some rabbits were given 100 mg of ibuprofen (Brufen) daily per os during the immobilization and remobilization periods. The controls were not given any drug. The development of the thickn...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748009098145

    authors: Michelsson JE

    更新日期:1980-01-01 00:00:00

  • The effect of transcutaneous electrical nerve stimulation (TNS) on joint pain in patients with rheumatoid arthritis.

    abstract::The effect of transcutaneous nerve stimulation (TNS) on joint pain was studied in patients with rheumatoid arthritis. Three different forms of TNS were used in an attempt to evaluate the influence of placebo effects. The results were evaluated by means of loading tests and from the patients' own assessments of pain re...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Mannheimer C,Lund S,Carlsson CA

    更新日期:1978-01-01 00:00:00

  • A follow-up study of the progress of keratoconjunctivitis sicca and response to treatment in primary Sjögren's syndrome.

    abstract::Thirty-four patients with Sjögren's syndrome were retrospectively examined in order to evaluate longitudinal alterations in objective ocular disease parameters and their possible relation to systemic bromhexine treatment. Twenty-three patients (68%) were initially found to respond to peroral bromhexine treatment and w...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748909099928

    authors: Kriegbaum NJ,von Linstow M,Oxholm P,Prause JU

    更新日期:1989-01-01 00:00:00

  • Anti-cardiolipin antibodies, Raynaud's phenomenon with digital ischemia, and non small cell carcinoma of the lung.

    abstract::Raynaud's phenomenon, digital ischemia, antinuclear antibodies and anticardiolipin antibodies are uncommon features of malignancy. The association of all of these in a patient with malignancy has not previously been reported. We describe a 52 year old woman with non small-cell carcinoma of the lung who also had Raynau...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/030097401300162978

    authors: Vaidya S,Logan JW

    更新日期:2001-01-01 00:00:00

  • Skin extensibility and consistency in patients with Ehlers-Danlos syndrome and benign joint hypermobility syndrome.

    abstract:OBJECTIVES:The reproducibility of clinical tests for skin extensibility and consistency, essential for differentiating between types of Ehlers-Danlos syndrome (EDS) and benign joint hypermobility syndrome (BJHS), is unknown. Paraclinical methods may provide objective differential diagnostic methods. METHODS:Six EDS, 1...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740802520714

    authors: Remvig L,Duhn PH,Ullman S,Kobayasi T,Hansen B,Juul-Kristensen B,Jurvelin JS,Arokoski J

    更新日期:2009-05-01 00:00:00

  • Treatment of intravenous immunoglobulin-resistant Kawasaki disease with methotrexate.

    abstract:OBJECTIVE:To evaluate the effect of low-dose oral methotrexate (MTX) as treatment for patients with Kawasaki disease (KD) resistant to intravenous immunoglobulin (IVIG). METHODS:The subjects were four patients with KD, aged 8 months to 8 years old, who showed persistent disease after treatment with high-dose IVIG (2 g...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740510026328

    authors: Ahn SY,Kim DS

    更新日期:2005-03-01 00:00:00

  • Reiter's syndrome in the population. An Interview Study.

    abstract::To obtain data on the incidence of Reiter's syndrome (RS) as well as on possible simultaneously appearing signs and symptoms of RS in sexual couples we have made interview reports of randomly selected 530 persons: 219 males and 311 females, aged 15 to 54. None had RS. Six males (2.7%) and seven females (2.3%) had a hi...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748209098181

    authors: Vilppula AH,Yli-Kerttula UI,Terho PE

    更新日期:1982-01-01 00:00:00

  • Enhanced breakdown of bovine articular cartilage proteoglycans by conditioned synovial medium. The effect of serum and dextran sulphate.

    abstract::Medium from cultured bovine synovial membrane when applied to articular cartilage from the same animal enhanced proteoglycan breakdown, as measured by the release of [35S]sulphate from prelabelled cartilage, principally by activating chondrocytes to secrete or activate their own enzymes. This effect persisted whether ...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009748209098113

    authors: Jones IL,Klämfeldt A,McGuire MB

    更新日期:1982-01-01 00:00:00

  • Effect of osmium tetroxide and 198Au in normal and arthritic rabbit knee joints.

    abstract::Antigen-induced arthritis (AIA) was induced in adult rabbit knee joints, using ovalbumin as antigen. After 4 weeks, intra-articular injections of 0.3 ml 1% osmium tetroxide or 100 muCi 198Au were given. The same injections were also given to normal animals. The animals were observed for up to 12 weeks. In the normal a...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:

    authors: Ahlberg KM,Henricson AS,Telhag HT,Wollheim FA

    更新日期:1978-01-01 00:00:00

  • The role of interleukin-10 promoter polymorphisms in primary Sjogren's syndrome.

    abstract:OBJECTIVE:To determine the impact of a broad spectrum of different polymorphisms within the interleukin-10 (IL-10) promoter gene on disease susceptibility to primary Sjogren's syndrome (pSS), clinical manifestations, and autoantibody production. METHODS:We genotyped 111 unrelated German Caucasian patients with pSS and...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740801910353

    authors: Willeke P,Gaubitz M,Schotte H,Becker H,Domschke W,Schlüter B

    更新日期:2008-07-01 00:00:00

  • Healing of erosions in rheumatoid arthritis remains elusive: results with 24 months of the anabolic agent teriparatide.

    abstract::Objective: Erosion healing in rheumatoid arthritis (RA) is difficult to demonstrate. This extension study aimed to determine whether 2 years of teriparatide (TPTD) produces erosion healing. Method: Subjects in a previous 12 month randomized controlled trial of TPTD in RA were invited to receive 12 additional months of...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009742.2020.1772362

    authors: Duryea J,Gravallese EM,Wortman JR,Xu C,Lu B,Kay J,Solomon DH

    更新日期:2021-01-01 00:00:00

  • Gastrointestinal bleeding: dyspeptic symptoms and clinical course in relation to use of non-steroidal antiinflammatory drugs.

    abstract::To study the symptoms of NSAID-associated gastroduodenal bleeding, 94 patients (median age 71 years, range 19-90), were included in a prospective, clinical trial where hematemesis or melena from gastroduodenal ulceration or haemorrhagic/erosive gastritis were the inclusion criteria. NSAID use within one month was stud...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章

    doi:10.3109/03009749109096813

    authors: Aabakken L,Weberg R,Lygren I,Eidsvoll B,Stray N,Osnes M

    更新日期:1991-01-01 00:00:00

  • Joint distension arthrography for disabling hip pain. A controlled clinical trial.

    abstract::Thirty-eight patients (age 27-73 years) with unilateral hip pain, restricted movement of the hip joint and radiologically no or only slight osteoarthrosis were studied in a double-blind controlled clinical trial. Twenty-one patients received active treatment with hip joint distension arthrography and 17 received place...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/03009748509165502

    authors: Høilund-Carlsen PF,Meinicke J,Christiansen B,Karle AK,Stage P,Uhrenholdt A

    更新日期:1985-01-01 00:00:00

  • The hURAT1 rs559946 polymorphism and the incidence of gout in Han Chinese men.

    abstract:OBJECTIVES:Our previous study identified rs559946, a human urate transporter 1 (hURAT1) single nucleotide polymorphism (SNP), as being significantly associated with risk of primary hyperuricaemia (HUA) in a Han Chinese population. In the current study we aimed to identify the genetic effects of rs559946 on gout suscept...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2013.808375

    authors: Li C,Yu Q,Han L,Wang C,Chu N,Liu S

    更新日期:2014-01-01 00:00:00

  • Spastic quadriparesis: an unusual early manifestation of systemic lupus erythematosus.

    abstract::Systemic lupus erythematosus (SLE) is an uncommon immunological disorder with multisystemic involvement. Neurological and neuropsychiatric manifestations in this disease are multifactorial and can involve any part of this system. We describe one patient presenting with spastic quadriparesis as an early clinical manife...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.1080/03009740310002579

    authors: Gupta A,Singh S,Singh P,Ahluwalia J,Rath S,Minz RW

    更新日期:2003-01-01 00:00:00

  • Home parenteral nutrition is beneficial in systemic sclerosis patients with gastrointestinal dysfunction.

    abstract:OBJECTIVES:To assess 12-month changes in nutritional status and quality of life (QoL) in systemic sclerosis (SSc) patients requiring home parenteral nutrition (HPN). METHOD:We conducted a retrospective, single-centre database analysis of SSc patients regarding a 12-month period of HPN at an interdisciplinary Universit...

    journal_title:Scandinavian journal of rheumatology

    pub_type: 杂志文章

    doi:10.3109/03009742.2015.1064543

    authors: Stanga Z,Aeberhard C,Schärer P,Kocher A,Adler S,Villiger PM

    更新日期:2016-01-01 00:00:00