Evidence for a dopaminergic involvement in the natriuretic action of centrally administered renin.

abstract：:The chronic mild stress (CMS) model has been used as an animal model of depression which induces anhedonic behavior in rodents. The present study was aimed to evaluate the behavioral and physiological effects of administration of beta-carboline harmine in rats exposed to CMS procedure. To this aim, after 40 days of ex...

journal_title：Brain research bulletin

authors： Fortunato JJ,Réus GZ,Kirsch TR,Stringari RB,Fries GR,Kapczinski F,Hallak JE,Zuardi AW,Crippa JA,Quevedo J

更新日期：2010-03-16 00:00:00

abstract：:This paper reviews and provides new data on the relationship of the peptide content in rat dorsal root ganglion (DRG) neurons to a) the neurofilament content of the soma and b) the conduction velocities of the fibres. The latter involved intracellular recordings made in vitro followed by dye injection and immunocytoch...

journal_title：Brain research bulletin

authors： Lawson SN,Perry MJ,Prabhakar E,McCarthy PW

更新日期：1993-01-01 00:00:00

abstract：:Sporadic Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder affected by amyloid and vascular pathogenesis. Brain insulin resistance (BIR) has been suggested as one of the pathomechanisms of sporadic AD. We investigated how the amyloid and vascular pathogenesis of AD interacts with BIR. We examined...

journal_title：Brain research bulletin

authors： Choi BR,Seo JH,Back DB,Han JS,Choi DH,Kwon KJ,Shin CY,Lee J,Kim HY

更新日期：2020-05-01 00:00:00

abstract：:Motor neurons are endowed with intrinsic and conditional membrane properties that may shape the final motor output. In the first half of this paper we present data on the contribution of I(h), a hyperpolarization-activated inward cation current, to phase-transition in motor neurons during rhythmic firing. Motor neuron...

journal_title：Brain research bulletin

authors： Kiehn O,Kjaerulff O,Tresch MC,Harris-Warrick RM

更新日期：2000-11-15 00:00:00

abstract：:Adenoviral vector directed gene transfer to rat facial motoneurons occurs efficiently following intra-parenchymal injection of relatively high dosages (> or =10(7) pfu per injection) of a prototype first generation adenoviral vector. However, high level of transgene expression, as observed during the first week follow...

journal_title：Brain research bulletin

authors： Hermens WT,Verhaagen J

更新日期：1998-09-15 00:00:00

abstract：:Central cholinergic neurons play an important role in learning and memory functions. The present study was undertaken to elucidate the pathological changes in learning function and acetylcholine metabolism of the cerebral cortex and hippocampus, following microsphere embolism in rats. Microspheres (48 microns) were in...

journal_title：Brain research bulletin

authors： Takagi N,Miyake K,Taguchi T,Sugita N,Takagi K,Tamada H,Takeo S

更新日期：1997-01-01 00:00:00

abstract：:We studied mitochondria in the satellite cell sheaths which envelope the spinal ganglion neurons of rabbits aged 12, 42, and 79 months. While the mean cytoplasmic volume of satellite cell sheaths did not change significantly with age, the mean percentage of cytoplasmic volume occupied by mitochondria decreased with ag...

journal_title：Brain research bulletin

authors： Martinelli C,Sartori P,Ledda M,Pannese E

更新日期：2003-07-15 00:00:00

abstract：:Diabetic cardiac autonomic neuropathy (DCAN) is a serious complication of diabetes mellitus, which often leads to cardiac dysfunction and even threatens patients' life. Osthole, a natural coumarin derivative, has anti-inflammatory, anti-oxidant and antihypertensive effects. The P2X3 receptor is related to DCAN. The ob...

journal_title：Brain research bulletin

authors： Wu B,Sheng X,Xu Z,Zhang Y,Dan Y,Guo J,Peng H,Liang S,Li G

更新日期：2020-04-01 00:00:00

abstract：:It was found that neurons in the posterior orbitofrontal cortex, area 13, of the rhesus monkey were activated from self-stimulation electrodes (in 142 of 168 possible instances), and that neurons in the anterior orbitofrontal areas were much less likely to be activated from the self-stimulation electrodes (in only 28 ...

journal_title：Brain research bulletin

authors： Mora F,Avrith DB,Rolls ET

更新日期：1980-03-01 00:00:00

abstract：:The subparafascicular thalamic nucleus (Spf) contains a substantial number of dopaminergic neurons. The present study was designed to investigate in the rat whether or not Spf neurons projecting to a variety of central nervous system structures are dopaminergic. The following eight structures were tested for projectio...

journal_title：Brain research bulletin

authors： Takada M

更新日期：1993-01-01 00:00:00

abstract：:Baroreceptor input plays a critical role in body fluid balance and the endocrine response to NaCl consumption [25]. Experiments were performed to characterize the alterations in salt intake that are seen after baroreceptor denervation. Using chronically baroreceptor denervated (SAD) or control (CON) male Sprague-Dawle...

journal_title：Brain research bulletin

authors： Rocha MJ,Callahan MF,Morris M

更新日期：1997-01-01 00:00:00

abstract：:In brainstem slices of male rats, we examined in single neurons of the medial vestibular nucleus (MVN) the effect of exogenous administration of estrogenic (17β-estradiol, E2) and androgenic (5α-dihydrotestosterone, DHT) steroids on the synaptic response to vestibular afferent stimulation. By whole cell patch clamp re...

journal_title：Brain research bulletin

authors： Grassi S,Scarduzio M,Panichi R,Dall'Aglio C,Boiti C,Pettorossi VE

更新日期：2013-08-01 00:00:00

abstract：:The role of several hippocampal innervations in the sensitivity to barbital-induced narcosis was studied in selected mice strains. The outbred and inbred mouse strains HS/lgb, SABRA/HUC, C57BL, CBA/LAC, and BALB/c were tested for barbital-induced sleep (315 mg/kg). The relatively short sleeping HS/lbg (HS) and the lon...

journal_title：Brain research bulletin

authors： Yanai J,Pick CG

更新日期：1995-01-01 00:00:00

abstract：:Although interleukin-1β (IL-1β) is a prototypical pro-inflammatory cytokine, the specific mechanisms underlying the role of its cognate receptor, the interleukin-1 receptor (IL-1R) in peripheral sensitization remain to be investigated. Since emerging evidence in the literature indicates that IL-1β can modulate membran...

journal_title：Brain research bulletin

authors： Kwon SG,Roh DH,Yoon SY,Choi SR,Choi HS,Moon JY,Kang SY,Beitz AJ,Lee JH

更新日期：2017-04-01 00:00:00

abstract：:The effects of intracerebroventricular (ICV) colchicine (70 micrograms per rat) on systolic pressures and levels of hexokinase activity in the hypothalamic paraventricular (PVH) and supraoptic (SON) nuclei were investigated in adult normotensive and spontaneously hypertensive rats (SHR). One day after colchicine injec...

journal_title：Brain research bulletin

authors： Krukoff TL,Vincent DH

更新日期：1989-07-01 00:00:00

abstract：:Although iron is involved in brain function, very little is known about the regulation of its concentrations in the central nervous system. We quantitatively measured the entry and exit rates of iron, transferrin (its major transport protein), and albumin in mice. The blood to brain transport of iron greater than tran...

journal_title：Brain research bulletin

authors： Banks WA,Kastin AJ,Fasold MB,Barrera CM,Augereau G

更新日期：1988-12-01 00:00:00

abstract：:Rats with chronic hippocampal electrode implants had afterdischarges induced with electrical stimulus intensities of 115, 200, and 800% of a previously determined threshold. Afterdischarge duration, postictal EEG depression duration, and the duration of postictal electrical hypoexcitability were assessed. After discha...

journal_title：Brain research bulletin

authors： Swartzwelder HS,Wegener ST,Johnson CT,Dyer RS

更新日期：1980-09-01 00:00:00

abstract：:Comparison of detailed physiological and morphological data shows that the hypothalamic aggression region in the rat largely coincides with the intermediate hypothalamic area. This region has a neuronal density of about 35.10(3) neurons per mm3, a synaptic density of about 300.10(6) per mm3, and a synapse to neuron ra...

journal_title：Brain research bulletin

authors： Aalders TT,Meek J

更新日期：1993-01-01 00:00:00

abstract：:Patterns of female sexual behavior in the hamster are qualitatively different from that observed in the rat. Hamsters demonstrate tonic immobility and a sustained lordotic response that can last for several minutes following minimal stimulation from the male while in rats, the lordotic response is highly dependent upo...

journal_title：Brain research bulletin

authors： Nance DM,Myatt GA

更新日期：1987-12-01 00:00:00

abstract：:The effect of epinephrine (EPI) on the activity of 150 periaqueductal gray (PAG) neurons was examined using extracellular recordings in an in vitro slice preparation. Drop application of EPI inhibited 45%, excited 35%, and had no effect on 20% of PAG neurons. Both the excitatory and inhibitory effects of EPI were of l...

journal_title：Brain research bulletin

authors： Jiang M,Chandler SD,Ennis M,Shipley MT,Behbehani MM

更新日期：1992-12-01 00:00:00

abstract：:This study aims to evaluate the neuroprotective effect of sodium butyrate against the pentylenetetrazol (PTZ)-induced kindling epilepsy. Sodium butyrate (SB) (5, 10 and 20 mg/kg) and sodium valproate for 40 days and PTZ (37 mg/kg) injection every day were conducted for Kunming mice, to investigate seizure intensity an...

journal_title：Brain research bulletin

authors： Li D,Bai X,Jiang Y,Cheng Y

更新日期：2020-12-28 00:00:00

abstract：:Since the groundbreaking work of Ramon y Cajal, the cerebellar Purkinje cell has always represented an ideal model for studying the organization, development and function of synaptic circuits. Purkinje cells receive distinct types of glutamatergic and GABAergic synapses, each characterized by exquisite sub-cellular an...

journal_title：Brain research bulletin

authors： Sassoè-Pognetto M,Patrizi A

更新日期：2017-03-01 00:00:00

abstract：:We recently reported that human recombinant interleukin-6 (hrIL-6) microinjected into the preoptic area (POA) of guinea pigs induced fever at high doses, suggesting that IL-6 may be another endogenous pyrogen. This study was undertaken to determine whether hrIL-6 affects the single-unit activity of thermosensitive and...

journal_title：Brain research bulletin

authors： Xin L,Blatteis CM

更新日期：1992-07-01 00:00:00

abstract：:Locomotor performance of transgenic R6/2 mice carrying the Huntington's disease (HD) mutation was assessed using four different tasks, fixed speed rotarod, accelerating rotarod, Digigait and footprint test. The tasks were compared directly in age- and CAG repeat-matched R6/2 mice. Accelerating rotarod was more sensiti...

journal_title：Brain research bulletin

authors： Pallier PN,Drew CJ,Morton AJ

更新日期：2009-03-30 00:00:00

abstract：:Melatonin (Mel) has neuroprotective effects; however, its roles in hypoxic-ischemic brain damage (HIBD) and the underlying mechanisms remain unknown. We aimed to explore its roles and mechanisms in a HIBD rat model. We found that exogenous Mel treatment ameliorated HIBD-induced pathological changes, inhibited neuronal...

journal_title：Brain research bulletin

authors： Gou Z,Su X,Hu X,Zhou Y,Huang L,Fan Y,Li J,Lu L

更新日期：2020-10-01 00:00:00

abstract：:Promoting remyelination and/or minimizing demyelination are key therapeutic strategies under investigation for diseases and injuries like multiple sclerosis (MS), spinal cord injury, stroke, and virus-induced encephalopathy. Myelination is essential for efficacious neuronal signaling. This myelination process is origi...

journal_title：Brain research bulletin

authors： Unal DB,Caliari SR,Lampe KJ

更新日期：2019-10-01 00:00:00

abstract：:To investigate the effect of stimulus presentation rate on the activity of primary somatosensory cortex, we performed echo-planar functional magnetic resonance imaging using a 1.5-tesla magnetic resonance system. Eight right-handed normal volunteers underwent functional magnetic resonance imaging during somatosensory ...

journal_title：Brain research bulletin

authors： Takanashi M,Abe K,Yanagihara T,Oshiro Y,Watanabe Y,Tanaka H,Hirabuki N,Nakamura H,Fujita N

更新日期：2001-01-15 00:00:00

abstract：:Neonatal rats, when spinalized on the fourteenth postnatal day, showed minimal recovery of function in their hindlimbs. Bridging the cut spinal cord with E16 fetal spinal cord tissue did not improve functional recovery. Bridging, plus treatment with GM1 ganglioside, caused a significant (p less than 0.05) improvement ...

journal_title：Brain research bulletin

authors： Commissiong JW,Sauve Y,Csonka K,Karoum F,Toffano G

更新日期：1991-07-01 00:00:00

abstract：:All the opiate-like peptides we tested (Met-enkephalin, (D-Ala2)-Met-enkephalin-NH2, beta-endorphin, (D-Ala2)-beta-endorphin, (D-Ala2)-alpha-endorphin, (D-Ala2)-gamma-endorphin) were capable of reducing distress vocalizations (DV's) in socially-isolated chicks when injected into the vicinity of the fourth ventricle in...

journal_title：Brain research bulletin

authors： Panksepp J,Vilberg T,Bean NJ,Coy DH,Kastin AJ

更新日期：1978-11-01 00:00:00

abstract：:Reserpine depletes dopamine (DA) levels and increases tyrosine hydroxylase (TH) activity in the rat corpus striatum. TH is activated not only by enhancement of DA neuronal impulse flow, but also by cessation of impulse flow. To assist in the understanding of the relative contribution of impulse flow to the regulation ...

journal_title：Brain research bulletin

authors： German DC,McMillen BA,Sanghera MK,Saffer SI,Shore PA

更新日期：1981-02-01 00:00:00