The prognostic significance of basic fibroblast growth factor in cutaneous malignant melanoma.

abstract：BACKGROUND:Some examples of Bowen disease lack the characteristic broad parakeratosis making their histopathologic diagnosis particularly difficult in small and incomplete biopsies. MATERIALS AND METHODS:The archives of our dermatopathology laboratory were searched for cases of Bowen disease with >75% orthokeratosis (...

journal_title：Journal of cutaneous pathology

authors： Idriss MH,Misri R,Böer-Auer A

更新日期：2016-01-01 00:00:00

abstract：:The low-fat and fat-free spindle cell lipomas (SCLs) are rare and often mistaken for other benign and malignant morphological mimics, because of the fact that the diagnosis relies on its non-lipogenic component analysis. Here, we report the clinicopathological features of two oral SCLs (low-fat and fat-free variants)....

journal_title：Journal of cutaneous pathology

authors： Rocha AFL,Miotto LN,Ferrisse TM,Silveira HA,Almeida LY,Bufalino A,Navarro CM,León JE

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:The cell origin of dermatofibroma (DF) has not been clarified satisfactorily. This study was undertaken to assess the distribution of fibroblasts and the relationship between fibroblasts and other constituent cells in DF by 47-kDa heat-shock protein (HSP47), a cell marker for skin fibroblast. METHODS:Immuno...

journal_title：Journal of cutaneous pathology

authors： Kuroda K,Tajima S

更新日期：2008-01-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorder (PTLD) is a lymphoid proliferation that develops as a complication of solid organ or bone marrow transplants. PTLD limited to the skin is very rare. Plasmacytoma-like PTLD is an uncommon variant of monomorphic PTLD. Its presentation in the skin is extraordinary with very fe...

journal_title：Journal of cutaneous pathology

authors： Molina-Ruiz AM,Pulpillo A,Lasanta B,Zulueta T,Andrades R,Requena L

更新日期：2012-07-01 00:00:00

abstract：:Subungual melanoma commonly presents with solitary longitudinal melanonychia. Herein, we report the case of a patient with subungual melanoma who developed involvement of three digits by three independent primary melanomas. A 98-year-old male patient presented with a two-year history of longitudinal melanonychia on th...

journal_title：Journal of cutaneous pathology

authors： Liu Y,Wang L

更新日期：2012-02-01 00:00:00

abstract：:This is the first report of spinous and follicular lichen nitidus associated with perifollicular granuloma formation. Clinicians and pathologists need to distinguish this stage of the disease from lichen scrofulosorum. ...

journal_title：Journal of cutaneous pathology

authors： Madhok R,Winkelmann RK

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Diagnosis of autoantibody- and immune complex-induced skin diseases is primarily based on direct immunofluorescence (DIF) microscopy. DIF staining is usually performed manually and, therefore, is labor intensive. The quality of immunohistochemical results considerably depends on the experience of the person ...

journal_title：Journal of cutaneous pathology

authors： Lemcke S,Sokolowski S,Rieckhoff N,Buschtez M,Kaffka C,Winter-Keil A,Schaller C,Rottmann N,Sadik CD,Stöcker W,Zillikens D,Schmidt E

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Alpha-methylacyl-CoA racemase (AMACR), also known as P504S, is a protein that plays an important role in mitochondrial and peroxisomal beta-oxidation of branched-chain fatty acid and bile acid intermediates. AMACR has been established as a valuable diagnostic marker for prostate cancer and has recently been ...

journal_title：Journal of cutaneous pathology

authors： Halsey MA,Calder KB,Mathew R,Schlauder S,Morgan MB

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Rhabdomyosarcoma is a malignant mesenchymal tumor with skeletal muscle differentiation. Primary cutaneous rhabdomyosarcoma is rare. We report a series of 11 cases of primary cutaneous rhabdomyosarcoma. METHODS:Cases diagnosed as rhabdomyosarcoma arising in the dermis/subcutis with no identified primary tumo...

journal_title：Journal of cutaneous pathology

authors： Marburger TB,Gardner JM,Prieto VG,Billings SD

更新日期：2012-11-01 00:00:00

abstract：:The skin biopsy specimens from six patients with primary mixed IgM-IgG cryoglobulinemia were examined by immunofluorescence, light and electron microscopy. The biopsy taken from the involved skin of one patient with leg ulcers revealed small blood vessel occlusions by cryoglobulin aggregates. Since a similar finding w...

journal_title：Journal of cutaneous pathology

authors： Berliner S,Weinberger A,Ben-Bassat M,Idesess C,Hazaz B,David M,Pinkhas J

更新日期：1982-04-01 00:00:00

abstract：:A 27-year-old woman developed many nodular lesions, ranging in diameter from 3 mm to 15 mm and clinically indistinguishable from dermatofibromas. Light microscopic examination showed large amounts of mucin, fibroblasts and histiocytes throughout the dermis. Electron microscopic study revealed wide electron lucent area...

journal_title：Journal of cutaneous pathology

authors： Zina AM,Bundino S

更新日期：1980-12-01 00:00:00

abstract：:Calciphylaxis is a rare syndrome of vascular calcification with thrombosis that occurs most often in patients with end-stage renal disease, and it frequently portends a guarded prognosis. Rarely, nonuremic calciphylaxis (NUC) may occur; in this context, a strongly supportive histology is crucial in establishing the di...

journal_title：Journal of cutaneous pathology

authors： Nathoo RK,Harb JN,Auerbach J,Guo R,Vincek V,Motaparthi K

更新日期：2017-12-01 00:00:00

abstract：:Differing classification schemes for malignant lymphomas have been used in Europe and the United States. Attempts to translate between the principle classifications have been unsuccessful and historically it has been difficult to arrive at an unified approach. In addition, many new lymphoma entities have been recogniz...

journal_title：Journal of cutaneous pathology

authors： Sander CA,Kind P,Kaudewitz P,Raffeld M,Jaffe ES

更新日期：1997-07-01 00:00:00

abstract：:Claudins are a family of transmembrane proteins involved in cell-to-cell adhesion and are believed to be the main component of tight junctions. Recent studies have suggested that some metastatic solid tumors lack claudin expression. It is unknown whether claudins play a role in cutaneous melanoma. Immunohistochemical ...

journal_title：Journal of cutaneous pathology

authors： Cohn ML,Goncharuk VN,Diwan AH,Zhang PS,Shen SS,Prieto VG

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum (PG) is a non-infectious, autoimmune, chronic ulcer of the skin, often co-existing with inflammatory bowel disease (IBD). Matrix metalloproteinases (MMPs) have been implicated as mediators of tissue destruction in chronic cutaneous and intestinal wounds. METHODS:Twenty-four skin biopsie...

journal_title：Journal of cutaneous pathology

authors： Bister V,Mäkitalo L,Jeskanen L,Saarialho-Kere U

更新日期：2007-12-01 00:00:00

abstract：:We describe a patient with thrombocytopenia-absent radius (TAR) syndrome, multisystemic Langerhans cell histiocytosis and multiple reticulohistiocytomas. A mutational study by massive sequencing identified the Val600Glu (V600E) BRAF mutation in the Langerhans cell histiocytosis lesions, but no molecular alterations we...

journal_title：Journal of cutaneous pathology

authors： Hipólito LN,Mendoza-Cembranos MD,Villaescusa MT,Jo-Velasco M,Requena L,Alegría-Landa V

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Histiocytic sarcoma is an exceedingly rare malignant neoplasm composed of cells with a monocyte/macrophage phenotype. In the current nosology of histiocytic neoplasms, histiocytic sarcoma is separate from indeterminate cell histiocytosis, a generally benign disorder characterized by proliferation of a CD1a+ ...

journal_title：Journal of cutaneous pathology

authors： Frater JL,Kling CW,Obadiah JM,Gardner LJ,Grosso LE,Resh B,Hurley MY

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Fibrofolliculomas and trichodiscomas are benign dermal neoplasms that likely derive from the mantle of the hair follicle and can occur sporadically or in association with Birt-Hogg-Dube syndrome (BHDS). Little is known about the pathogenesis and immunophenotypic properties of these entities. METHODS:We inve...

journal_title：Journal of cutaneous pathology

authors： Collins GL,Somach S,Morgan MB

更新日期：2002-10-01 00:00:00

abstract：:The rare presentation of choriocarcinoma as a cutaneous metastasis in a 23-year-old male is reported. Histological and immunohistochemical analysis of the biopsy material demonstrated two distinct cell populations, syncytiotrophoblasts and cytotrophoblasts, with syncytiotrophoblasts strongly positive for human chorion...

journal_title：Journal of cutaneous pathology

authors： Chhieng DC,Jennings TA,Slominski A,Mihm MC Jr

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Expression of programmed death ligand 1 (PD-L1) by cutaneous squamous cell carcinomas has been shown to correlate with advanced disease and risk of metastasis. Lymphocyte activation gene 3 (LAG-3, or CD223) is an inhibitory receptor that interacts with the PD-L1 axis, which has been shown to be a marker of i...

journal_title：Journal of cutaneous pathology

authors： Wu S,Slater NA,Sayed CJ,Googe PB

更新日期：2020-10-01 00:00:00

abstract：:In lymph nodes, classical Hodgkin lymphoma can typically be distinguished from non-Hodgkin lymphoma (NHL) by the presence of Hodgkin and Reed-Sternberg cells that co-express CD30 and CD15. However, anaplastic large cell lymphoma (ALCL) and diffuse large B-cell lymphoma (DLBCL) can show identical features, and some cas...

journal_title：Journal of cutaneous pathology

authors： Cho RJ,McCalmont TH,Ai WZ,Fox LP,Treseler P,Pincus LB

更新日期：2012-06-01 00:00:00

abstract：:The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with th...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Benign lichenoid keratosis (BLK) is a well-known clinicopathologic entity and several histopathologic patterns have been described. Features mimicking mycosis fungoides (MF) in clinically typical BLKs have not yet been emphasized. The aim of this study was to confirm the occurrence of an MF-like pattern of B...

journal_title：Journal of cutaneous pathology

authors： Al-Hoqail IA,Crawford RI

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:Lichen planopilaris (LPP) and frontal fibrosing alopecia (FFA) represent 2 entities that cause primary cicatricial alopecia. These entities are clinically different; nevertheless, the literature suggests that FFA represents a form of LPP. The main argument in support of this hypothesis is that previous studi...

journal_title：Journal of cutaneous pathology

authors： Gálvez-Canseco A,Sperling L

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:CD44 is a membrane glycoprotein and the major cell-surface receptor of hyaluronate (HA). Lack of CD44 expression in mouse epidermis leads to an abnormal HA accumulation in the dermis, indicating an important role of CD44 in local HA metabolism. Decrease of epidermal CD44 expression in patients of lichen scle...

journal_title：Journal of cutaneous pathology

authors： Kaya G,Augsburger E,Chavaz P,Saurat JH

更新日期：2006-03-01 00:00:00

abstract：:Cutaneous lymphadenoma is an uncommon benign neoplasm often considered to be an adamantinoid variant of trichoblastoma. Lesions present in both sexes, between 14 and 87 years of age, and are mainly located on the head and neck. Cases in children are rare and there is only 1 previous case of a congenital lymphadenoma. ...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Nicklaus-Wollenteit I,Sathishkumar D,Diba V,Richard B,Carr R,Moss C,Nagy A,Ogboli M,Colmenero I

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Erythema elevatum diutinum (EED) is a rare vasculitis with variable clinical presentation which diagnosis can be challenging. Herein we want to describe the clinicopathological spectrum of findings in five cases of EED. METHODS:We retrospectively analyzed five cases in a single institution collected over a ...

journal_title：Journal of cutaneous pathology

authors： Sardiña LA,Jour G,Piliang MP,Bergfeld WF

更新日期：2019-02-01 00:00:00

abstract：:The term "outer root sheath acanthoma" is proposed to specify a distinctive keratosis exhibiting outer root sheath differentiation. This lesion features anastamosing columns of keratinocytes emanating from the undersurface of the epidermis that respectively demonstrate, with progressive descent into the upper dermis, ...

journal_title：Journal of cutaneous pathology

authors： Reichel M,Heilman ER

更新日期：1999-10-01 00:00:00

abstract：:Two patients with solitary lesions of pagetoid reticulosis are presented. A third case with disseminated lesions and similar microscopic detail is also reported. Lighg microscopic findings include an abnornal cell infiltrate confined to the epidermis and distributed diffusely in a pagetoid pattern. In ultrathin sectio...

journal_title：Journal of cutaneous pathology

authors： Wood WS,Killby VA,Stewart WD

更新日期：1979-04-01 00:00:00

abstract：:A histologically unique condition of the sweat duct was found in a miliaria-like papular eruption on the extensor surfaces of extremities of a 41-year-old female patient. The hypertrophic epithelium of the sweat duct wall consisted of extensively vacuolated clear cells. There was mild hyperkeratosis around the sweat d...

journal_title：Journal of cutaneous pathology

authors： Izaki S,Kono E,Hirai A,Kitamura K

更新日期：1994-06-01 00:00:00