Abstract:
RATIONALE AND OBJECTIVES:Renovascular smooth muscle contractility, an important factor in contrast media-induced nephrotoxicity, depends on intracellular Ca2+ concentration, which is composed of extracellular Ca2+ influx and intracellular Ca2+ release. These factors were investigated in contrast media-induced renal vasoconstriction in an in vitro model. METHODS:KCl-induced isometric contractions of rabbit renal artery were compared with contractions elicited by contrast media (diatrizoate, iohexol, iopamidol). Measurements were made after incubation with the Ca2+ channel blockers nifedipine, verapamil, and diltiazem to assess the role of extracellular Ca2+ influx and after ryanodine and thapsigargin to investigate the role of intracellular Ca2+ release. RESULTS:The Ca2+ channel blockers partially inhibited contractions induced by contrast media, while KCl-induced contractions were completely abolished. Ryanodine and thapsigargin also markedly inhibited contrast media-induced contractions. CONCLUSION:Ionic and nonionic contrast media induced quantitatively different renal vasocontractions. Ca2+ channel blockers inhibited this vasocontraction only slightly compared with intracellular Ca2+ release blockers.
journal_name
Acad Radioljournal_title
Academic radiologyauthors
Drescher P,Rauch D,Madsen POdoi
10.1016/s1076-6332(96)80298-4subject
Has Abstractpub_date
1996-11-01 00:00:00pages
912-8issue
11eissn
1076-6332issn
1878-4046journal_volume
3pub_type
杂志文章abstract:RATIONALE AND OBJECTIVES:To demonstrate that a massive training artificial neural network (MTANN) can be adequately trained with a small number of cases in the distinction between nodules and vessels (non-nodules) in thoracic computed tomography (CT) images. MATERIALS AND METHODS:An MTANN is a trainable, highly nonlin...
journal_title:Academic radiology
pub_type: 临床试验,杂志文章
doi:10.1016/j.acra.2005.06.017
更新日期:2005-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Ultrasonography (US) is becoming popular for the assessment of adiposity, but no one has studied this tool in the light of its potential limitations. Our purpose was to investigate the impact of technical conditions on the evaluation of abdominal fat by US. MATERIALS AND METHODS:Forty-five hea...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.07.009
更新日期:2013-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to determine whether uterine leiomyoma can be distinguished from uterine leiomyosarcoma on ultrasound (US), computed tomography (CT), and/or magnetic resonance imaging (MRI) without diffusion-weighted imaging. MATERIALS AND METHODS:Institutional review board approval was obtai...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.06.004
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To better prepare radiology residents for providing care within the context of the larger health care system, this study evaluated the feasibility and impact of a curriculum to enhance radiology residents' understanding and ability to apply concepts from medical management and industrial and op...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2012.09.025
更新日期:2013-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to determine the sonographic visibility of implanted collagen-based breast biopsy marker clips in the clinic and operating room. MATERIALS AND METHODS:Female patients aged > or =18 years who presented for preoperative surgical evaluation within 4 weeks of ultrasound-g...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2009.10.017
更新日期:2010-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To identify magnetic resonance (MR) imaging characteristics allowing specific preoperative discrimination between colloid cysts (CCs) of the sellar region and third ventricle (CC3rdv) versus Rathke's cleft cysts (RCCs). MATERIALS AND METHODS:MR imaging data of 38 patients with histologically p...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2013.08.014
更新日期:2013-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:It was hypothesized that perfusion computed tomography (CT), blood flow (BF), blood volume (BV), and vascular permeability surface area (PS) product parameters would be predictive of therapeutic anticancer agent uptake in pancreatic cancer, facilitating image-guided interpretation of human trea...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.12.014
更新日期:2015-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Since the initial description of an intralobar attenuation gradient by Webb et al, it has been suggested that departure from the intralobar attenuation gradient could indicate early lung diseases. However, its significance has not been determined in detail. We aimed to quantify the anteroposter...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2005.10.025
更新日期:2006-05-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Cellulitis is a common cause for emergency department (ED) presentation and subsequent hospital admission. Underlying fracture, osteomyelitis, or foreign body is often considered in the clinical evaluation of these patients. Accordingly, plain radiographs (XRs) of the affected extremity are oft...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2015.08.002
更新日期:2015-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate the feasibility and performance of an x-ray beam equalization system for chest radiography using anthropomorphic phantoms. MATERIALS AND METHODS:Area beam equalization involves the process of the initial unequalized image acquisition, attenuator thickness calculation, mask generati...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00730-x
更新日期:2004-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:This study aimed to test high temporal resolution dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) for different zones of the prostate and evaluate its performance in the diagnosis of prostate cancer (PCa). Determine whether the addition of ultrafast DCE-MRI improves the perform...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.10.004
更新日期:2018-03-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:There is discordance between the American Board of Radiology (ABR) and many radiology trainees with respect to the most appropriate means to prepare for the ABR Core Examination. Whereas the ABR suggests that participation in routine clinical examination interpretation best prepares a trainee f...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.10.004
更新日期:2020-02-01 00:00:00
abstract::Despite the widespread belief that advanced imaging should be very helpful in guiding oncology treatment decision and improving efficiency and success rates in treatment clinical trials, its acceptance has been slow. Part of this is likely attributable to gaps in study design and statistical methodology for these imag...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2017.03.002
更新日期:2017-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Digitizing images for use in case presentations based on hardcopy films, slides, photographs, negatives, books, and videos can present a challenging task. Scanners and digital cameras have become standard tools of the trade. Unfortunately, use of these devices to digitize multiple images in man...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/s1076-6332(03)00010-2
更新日期:2003-08-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To determine whether an unenhanced low-dose image acquired during automated contrast bolus timing can be used to assess hepatic steatosis. MATERIALS AND METHODS:Fifty subjects (29 male, 21 female; 26-92 years; mean body mass index (BMI; 26.9) with abdominal multiphasic computed tomography were...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.02.013
更新日期:2011-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Evidence is inconsistent about whether radiologists' interpretive performance on a screening mammography test set reflects their performance in clinical practice. This study aimed to estimate the correlation between test set and clinical performance and determine if the correlation is influence...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2017.03.016
更新日期:2017-10-01 00:00:00
abstract::In medicine, an eponym is a word-typically referring to an anatomic structure, disease, or syndrome-that is derived from a person's name. Medical eponyms are ubiquitous and numerous. They are also at times controversial. Eponyms reflect medicine's rich and colorful history and can be useful for concisely conveying com...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2016.04.011
更新日期:2016-10-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate, in a group of candidates for liver donation, the role of unenhanced computed tomography (CT) and magnetic resonance (MR) as noninvasive means to measure hepatic steatosis (HS). MATERIALS AND METHODS:Sixty-one consecutive candidates underwent CT and MR evaluation for liver donation...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2014.01.007
更新日期:2014-04-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Mammographic breast density is an important and widely accepted risk factor for breast cancer. A statement about breast density in the mammographic report is becoming a requirement in many States. However, there is significant inter-observer variation between radiologists in their interpretatio...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.07.011
更新日期:2011-11-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To document the frequency of normal and anomalous drainage patterns of the pulmonary veins, and to establish normal values for pulmonary vein ostial diameters, and distance to first bifurcation using multidetector computed tomography, as pertinent to ablation procedures for atrial fibrillation....
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2006.11.004
更新日期:2007-02-01 00:00:00
abstract::The purpose of this work is to provide current information on the rapidly evolving subject of nephrogenic systemic fibrosis (NSF), to establish the radiologic approach to the management of high-risk patients for NSF, and to assess the probabilistic risk of NSF compared to contrast induced nephropathy (CIN), as encount...
journal_title:Academic radiology
pub_type: 杂志文章,评审
doi:10.1016/j.acra.2009.01.001
更新日期:2009-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To quantify the use of Diagnostic Certainty Phrases (DCP) in radiology reports, including DCPs with good agreement (including "diagnostic of," "unlikely" and "represents") in connoting degree of certainty between providers based on previous studies; and to assess whether modality, presence of a...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.10.017
更新日期:2019-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Our goal was to develop and evaluate software to support a computer assisted mammography feedback program (CAMFP) to be used for continuing medical education (CME). MATERIALS AND METHODS:Thirty-five radiologists from our region signed consent to participate in an institutional review board-app...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2007.05.018
更新日期:2007-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:Early loss of a sensory modality has been associated with cortical reorganization in both animal models and humans. The purpose of this study was to map visual activation with functional magnetic resonance (MR) imaging and to document possible developmental reorganization in the temporal lobe c...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/S1076-6332(03)80684-0
更新日期:2001-07-01 00:00:00
abstract::Innovation in the field of diagnostic imaging is based primarily on the availability of new and improved equipment that opens the door for new clinical applications. Payments for these imaging procedures are subject to complex Medicare price control schemes, affecting incentives for appropriate use and innovation. Ach...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2011.04.007
更新日期:2011-09-01 00:00:00
abstract:RATIONALE AND OBJECTIVE:Abnormal neurodevelopment may play a role in the pathophysiology of schizophrenia. We used deformation-based morphometry to examine voxel-wise age-related changes in patients with schizophrenia compared with healthy brains. MATERIALS AND METHODS:We used a set of skull-stripped brains from an im...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2004.06.009
更新日期:2005-01-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:The aim of this study was to prospectively examine the impact of a tablet-based curriculum on the radiology resident educational experience. MATERIALS AND METHODS:A comprehensive tablet-based curriculum was developed by creating subspecialty modules with appropriate content level for each requ...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2018.05.018
更新日期:2018-12-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:We sought to evaluate the diagnostic performance of high-resolution magnetic resonance imaging (MRI) and conventional MRI of the knee on a standard-field-strength MRI system compared to arthroscopic findings in patients with suspected meniscal tears. MATERIALS AND METHODS:Forty-two patients (2...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2008.02.007
更新日期:2008-07-01 00:00:00
abstract:RATIONALE AND OBJECTIVES:To evaluate conspicuity of screen-detected cancers on two-dimensional synthetic mammography (SM) reconstructed from digital breast tomosynthesis (DBT) compared to two-dimensional full field digital mammography (FFDM). MATERIALS AND METHODS:IRB-approved retrospective review of consecutive scree...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2019.06.008
更新日期:2020-06-01 00:00:00
abstract::As ACGME (Accreditation Council for Graduate Medical Education) requirements have expanded and become increasingly more complex, so has the role of the program coordinator. Over the last decade, the knowledge and skills required to capably administer residency and fellowship training programs have increased in both vo...
journal_title:Academic radiology
pub_type: 杂志文章
doi:10.1016/j.acra.2016.12.021
更新日期:2017-06-01 00:00:00