Abstract:
:High levels of the amino acid neurotransmitter glutamate were found in the goldfish hypothalamus and pituitary using high performance liquid chromatography with fluorometric detection. A specific polyclonal antibody to glutamate was generated in the rabbit for immunocytochemistry. Localization studies demonstrated that glutamatergic neurons of undetermined origin innervate the particular part of the goldfish adenohypophysis where somatotrophs and gonadotrophs are located. Intraperitoneal and brain third ventricle injection of the glutamate agonist N-methyl-D,L-aspartic acid (NMA) inhibited GH release in vivo. The gonadal steroid estradiol plays an important role in regulating GH secretion by stimulating basal serum GH levels and enhancing the inhibitory effects of NMA on GH secretion. Taken together, these results demonstrate that glutamate is an important regulator of GH secretion in goldfish.
journal_name
Gen Comp Endocrinoljournal_title
General and comparative endocrinologyauthors
Trudeau VL,Sloley BD,Kah O,Mons N,Dulka JG,Peter REdoi
10.1006/gcen.1996.0103subject
Has Abstractpub_date
1996-08-01 00:00:00pages
129-37issue
2eissn
0016-6480issn
1095-6840pii
S0016-6480(96)90103-3journal_volume
103pub_type
杂志文章abstract::Avian reproduction entails complex endocrine interactions at the hypothalamic and ovarian levels. The initiation of the reproductive season is due to the reduction in melatonin and GnIH production as day length increases. The decline in GnIH permits GnRH and gonadotropin secretion starting follicle growth. Follicular ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章,评审
doi:10.1016/j.ygcen.2014.03.040
更新日期:2014-07-01 00:00:00
abstract::Gonadotropin-releasing hormone (GnRH) was detected in the brains of passerine birds, a recently evolved and diverse avian group. The molecular forms of GnRH in two species of birds under breeding conditions were deduced using methods of HPLC and immunology. The brain extracts of song sparrows (Melospiza melodia) conta...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(88)90024-x
更新日期:1988-03-01 00:00:00
abstract::Development patterns in birds range from precocial species, which hatch chicks largely capable of independent existence, to altricial species, chicks of which are highly dependent on their parents for extended periods. Previous work indicates precocial chicks have a robust corticosterone response from hatching whereas...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2008.02.007
更新日期:2008-05-15 00:00:00
abstract::The present work studied the PGF2 alpha and 17 beta-estradiol plasma levels during ovulation, and the in vitro effects of mammalian gonadotropin-releasing hormone (mGnRH) on ovarian and oviductal production of prostaglandin F2 alpha (PGF2 alpha) and 17 beta-estradiol during four different stages of the annual sexual c...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(92)90018-f
更新日期:1992-08-01 00:00:00
abstract::Since an extrapancreatic source of insulin has been postulated in the chick embryo, insulin was sought by immunohistochemistry in the embryo before and after development of the pancreas and other tissues. Using for the first time an antiserum specific for chicken insulin, localization of insulin was investigated in wh...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(89)90102-0
更新日期:1989-02-01 00:00:00
abstract::Previous studies have provided evidence that D-Asp plays a role in steroid-mediated reproductive biology in amphibians, reptiles, birds and mammals. To examine the molecular involvement of D-Asp on steroidogenic pathway regulation, we analysed the expression of StAR, P450 aromatase and 5αRed2 mRNAs in Pelophylax escul...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2011.10.006
更新日期:2012-01-01 00:00:00
abstract::Extrapituitary expression of the growth hormone (GH) gene has been reported for the immune system of various vertebrates. In the rainbow trout (Oncorhynchus mykiss), GH mRNA could be detected in several lymphoid organs and leucocytes by reverse transcriptase-polymerase chain reaction (RT-PCR). To understand the contro...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2005.01.008
更新日期:2005-05-15 00:00:00
abstract::The response of plasma prolactin (PRL) to manipulations of plasma calcium were investigated in coho salmon. Injection of 3.16 mumol EGTA/10 g body weight (to reduce the plasma calcium activity) resulted in significantly higher plasma PRL levels. Lower doses of EGTA (1.06 and 2.13 mumol/10 g body wt) had no effect on p...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(89)90197-4
更新日期:1989-03-01 00:00:00
abstract::Effects of growth hormone (GH) on the synthesis of mucopolysaccharide by ceratobranchial cartilages of the Japanese eel, Anguilla japonica, were examined by monitoring the in vitro uptake of [35S]sulfate. The [35S]sulfate uptake decreased rapidly to one-third of the initial level during the first 3 days after hypophys...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(90)90117-5
更新日期:1990-08-01 00:00:00
abstract::Histochemical assays, hormonal quantitation, and steroid biosynthetic studies were carried out with adrenal glands obtained from four stranded whales of two different species (Kogia breviceps and Mesoplodon europaeus), and selected comparisons were made with the results of similar studies of adrenals from terrestrial ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(87)90041-4
更新日期:1987-11-01 00:00:00
abstract::Pregnancy and lactation are key times in the life of female mammals when energetic resources must be brought to bear to produce and nurture offspring. Changes in glucocorticoid (GC) levels are central to this objective, due to their roles in modulating development and physiology and in mediating energetic tradeoffs. W...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2015.11.004
更新日期:2016-06-01 00:00:00
abstract::Four genomes and two transcriptomes from six Chelicerate species were analyzed for the presence of neuropeptide and neurohormone precursors and their GPCRs. The genome from the spider Stegodyphus mimosarum yielded 87 neuropeptide precursors and 101 neuropeptide GPCRs. High neuropeptide transcripts were also found in t...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2015.07.014
更新日期:2016-11-09 00:00:00
abstract::Plasma concentrations of thyroid hormones (TH) were investigated during the extended posthatching developmental period (approximately 11 months) of a semi-altricial bird species, the king penguin (Aptenodytes patagonicus). The first period of growth in summer was marked by a progressive rise in plasma T4 concentration...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2004.02.003
更新日期:2004-05-01 00:00:00
abstract::To examine the physiological role of calcitonin (CT) in calcium homeostasis of teleosts, we compared calcium and CT levels in freshwater eels fed a high calcium-consomme solution (Ca2+: 1.25 M; 1 ml/100 g body wt) into the stomach (Experiment I), and in freshwater eels transferred from freshwater to seawater (Experime...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1999.7261
更新日期:1999-06-01 00:00:00
abstract::Renal actions of arginine vasotocin (AVT) and atrial natriuretic peptide (ANP) in teleosts are poorly defined. Administration of these hormones changes renal function, largely explained by systemic vascular effects. The present experiments examine the potential direct action of these hormones on the teleost nephron. T...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1993.1046
更新日期:1993-03-01 00:00:00
abstract::The binding of the synthetic glucocorticoid dexamethasone (dex) to Rana catesbeiana tadpole liver, intestine, and tailfin cytosol during both spontaneous and triiodothyronine (T3)-induced metamorphosis has been examined. No change was observed in the dissociation constant (KD) in the liver or intestine during either s...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(84)90173-4
更新日期:1984-05-01 00:00:00
abstract::The larval ring gland and adult corpus allatum (CA) of Drosophila melanogaster produce at least three sesquiterpenoid products: methyl farnesoate (MF), juvenile hormone III (JHIII), and JHIII bisepoxide (JHB(3)). Our understanding of neuropeptide regulation of sesquiterpenoid biosynthesis in D. melanogaster has been h...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2011.12.039
更新日期:2012-05-01 00:00:00
abstract::Neuropeptide Y (NPY) is a 36 amino-acid amidated peptide of the pancreatic polypeptide (PP) family, which plays an important role in appetite regulation and energy expenditure in mammals. Although several teleost NPY have been identified, its roles remain unclear in fish. We herein reported on the molecular cloning, t...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2017.11.017
更新日期:2018-04-01 00:00:00
abstract::The present study was designed to investigate potential effects of arachidonic acid (ARA) on the reproductive physiology of female Atlantic cod (Gadus morhua L.). Two-year old Atlantic cod of both sexes were equally distributed into eight sea cages after completion of their first spawning in May 2005. Four experimenta...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2017.05.020
更新日期:2017-09-01 00:00:00
abstract::Cardiovascular responses to synthetic eel [Asn1, Val5, Gly9]-ANG-I, ANG-III (2-8), and ANG-I (1-7) were measured in conscious and resting freshwater North American eels. Indwelling Doppler flow probes were placed on the ventral and dorsal aortas, a pressure catheter in the lienomesenteric artery, and a peptide deliver...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1995.1025
更新日期:1995-02-01 00:00:00
abstract::Cholesterol transport across the mitochondrial membrane is rate-limiting for steroidogenesis in vertebrates. Previous studies in fish have characterized expression of the steroidogenic acute regulatory protein, however the function and regulation of other genes and proteins involved in piscine cholesterol transport ha...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2011.04.027
更新日期:2011-08-01 00:00:00
abstract::Hormones play key, functional roles in mediating the tradeoff between survival and reproduction. Glucocorticoid hormones can inhibit reproduction and improve chances of survival during periods of stress. However, glucocorticoid hormones are, at times, also associated with successfully engaging in energetically costly ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2014.08.008
更新日期:2014-11-01 00:00:00
abstract::The activities of oxidative enzymes of hepatic mitochondria of Anabas testudineus increased following exogenous administration of hydrocortisone and corticosterone. The inhibitors of protein synthesis prevented the hormone-mediated increase of hepatic enzymes, suggesting that corticosteroids regulate the oxidative met...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/0016-6480(90)90017-g
更新日期:1990-05-01 00:00:00
abstract::Gonadotropin-releasing hormones (GnRH) constitute a family of neuropeptides which are important regulators of reproduction in vertebrates. The effect of mammalian GnRH (mGnRH), salmon GnRH, chicken GnRH-I, chicken GnRH-II, and lamprey GnRH-I on [3H]thymidine incorporation into DNA of dissociated gonadal cells of marin...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1998.7186
更新日期:1999-01-01 00:00:00
abstract::Insulin-like growth factor-1 (IGF-1) is a member of the vertebrate insulin/insulin-like growth factor/relaxin gene family necessary for growth, reproduction, and survival at both the cellular and organismal level. Its sequence, protein structure, and function have been characterized in mammals, birds, and fish; howeve...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2012.04.022
更新日期:2012-08-01 00:00:00
abstract::This study was conducted at the Bukhara breeding centre (Ouzbekistan, Central Asia) on Persian gazelles (Gazella subgutturosa subgutturosa) and at Thumammah (Saudi Arabia) on sand gazelles (Gazella subgutturosa marica). Plasma prolactin (PRL) and progesterone were determined in groups of females. Because these females...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.2000.7561
更新日期:2001-01-01 00:00:00
abstract::The effect of an exogenous glucocorticoid on the lipid metabolism and fatty acid pattern of skeletal muscle in broiler chickens (Gallus gallus domesticus) was investigated in vivo and in vitro. Male Arbor Acres chickens were subjected to dexamethasone (DEX) treatment for 3days. We found that DEX retarded body growth, ...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2012.09.013
更新日期:2012-12-01 00:00:00
abstract::There are more CRH-like immunoreactive neurons in the preoptic nucleus and nucleus lateralis tuberis in the brain of feral brown trout, Salmo trutta, living in cadmium- and zinc-contaminated regions of the Eagle River than in fish from an uncontaminated control site. Histological analyses revealed that interrenal cell...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1997.7000
更新日期:1997-12-01 00:00:00
abstract::Melatonin binding sites were examined in the quail eye using 2-[125]iodomelatonin. Radioreceptor assays indicated similar binding sites in membrane preparations of neural retina (NR) and choroid-retinal pigment epithelium (C-RPE) eye components. In both tissues binding of the radioligand was specific, saturable, and o...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1006/gcen.1995.1148
更新日期:1995-11-01 00:00:00
abstract::In vitro experiments were conducted to test the hypothesis that 17alpha,20beta-dihydroxy-4-prengnen-3-one (17,20-P) regulates cortisol metabolism in Pacific salmon. In both rainbow trout and coho salmon, cortisol metabolism was significantly higher in the kidney compared to the liver. The rainbow trout kidney converte...
journal_title:General and comparative endocrinology
pub_type: 杂志文章
doi:10.1016/j.ygcen.2009.06.003
更新日期:2010-01-01 00:00:00