Immunohistochemical localization of insulin in the chick embryo during development.

Abstract:

:Since an extrapancreatic source of insulin has been postulated in the chick embryo, insulin was sought by immunohistochemistry in the embryo before and after development of the pancreas and other tissues. Using for the first time an antiserum specific for chicken insulin, localization of insulin was investigated in whole embryos (Days 1-8) and in brain, kidney, liver, and pancreas (Days 9-21 and 30). Results indicate the presence of immunoreactive insulin in pancreatic islets from Day 5 onward with an increase in staining intensity during development. Insulin was not detected in other tissues of the early developing embryo or in brain, liver, or kidney in later development. These data suggest that although extrapancreatic insulin has been reported, concentrations are not high enough in tissues to be detected with a specific, homologous antiserum and sensitive immunohistochemical techniques.

journal_name

Gen Comp Endocrinol

authors

Bagnell CA,Baker NK,McMurtry JP

doi

10.1016/0016-6480(89)90102-0

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

293-8

issue

2

eissn

0016-6480

issn

1095-6840

pii

0016-6480(89)90102-0

journal_volume

73

pub_type

杂志文章
  • Climate change impacts on fish reproduction are mediated at multiple levels of the brain-pituitary-gonad axis.

    abstract::Anthropogenic emissions of carbon dioxide in the atmosphere have generated rapid variations in atmospheric composition which drives major climate changes. Climate change related effects include changes in physico-chemical proprieties of sea and freshwater, such as variations in water temperature, salinity, pH/pCO2 and...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygcen.2020.113439

    authors: Servili A,Canario AVM,Mouchel O,Muñoz-Cueto JA

    更新日期:2020-05-15 00:00:00

  • Purification, characterization and expression of two vitellogenins in the Indian freshwater murrel Channa punctatus.

    abstract::The present study was undertaken to characterize different vitellogenins in Channa punctatus. Protein purification by gel chromatography followed by fast protein liquid chromatography (FPLC) revealed existence of two different Vg forms. Liquid chromatography tandem mass spectrophotometry (LC-MS/MS) suggested the exist...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2013.05.002

    authors: Rawat VS,Pipil S,Sharma L,Sehgal N

    更新日期:2013-08-01 00:00:00

  • Ultrastructural comparison of the perisympathetic organs in three Coleoptera: Chrysocarabus auronitens F., Oryctes rhinoceros L. and Tenebrio molitor L.

    abstract::Ultrastructural comparison of different types of perisympathetic organs (POs) in three species of Coleoptera (Chrysocarabus auronitens, Oryctes rhinoceros, and Tenebrio molitor) showed that the structure of these organs was not related to their morphological types but to their topography. Two kinds of PO structure may...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(83)90203-4

    authors: Provansal-Baudez A,Baudry-Partiaoglou N

    更新日期:1983-03-01 00:00:00

  • Purification and characterization of plasma vitamin D binding protein from the snapping turtle, Chelydra serpentina.

    abstract::Vitamin D binding protein (DBP) was isolated from the plasma of the snapping turtle, Chelydra serpentina (mixed sex adult), and compared with the previously characterized dual function binding plasma protein that binds both thyroxine (T4) and vitamin D (tsTDBP) in an emydid turtle, Trachemys scripta. Purification of C...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1006/gcen.1996.0182

    authors: Horowitz M,Licht P

    更新日期:1996-12-01 00:00:00

  • Morphological and endocrine correlates of the reproductive cycle of the aplacental viviparous dogfish, Squalus acanthias.

    abstract::Pregnant female spiny dogfish were captured off the coasts of Maine and Massachusetts and morphometric and gravimetric analyses of the liver, gonad, and reproductive tract correlated with the reproductive cycle. Plasma samples were taken and circulating steroids (progesterone, testosterone, and estradiol) were measure...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(87)90266-8

    authors: Tsang PC,Callard IP

    更新日期:1987-05-01 00:00:00

  • Effects of pimozide and des Gly10,[D-Ala6]luteinizing hormone-releasing hormone ethylamide on serum gonadotropin concentrations, germinal vesicle migration, and ovulation in female goldfish, Carassius auratus.

    abstract::In gravid female goldfish held at 10-12 degrees, a single injection of des Gly10,[D-Ala6]luteinizing hormone-releasing hormone ethylamide (LHRH-A), or 2 injections of LHRH-A given 12 hr apart, increased serum gonadotropin (GtH) concentrations, but did not stimulate germinal vesicle migration or ovulation. Injection of...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(83)90155-7

    authors: Chang JP,Peter RE

    更新日期:1983-10-01 00:00:00

  • Ultrastructural features of neurosecretory cells in the medulla externa of the crayfish eyestalk.

    abstract::A conglomerate of 8-12 neurons in the medulla externa of the crayfish eyestalk was explored in their reaction to a polyclonal antibody against the tyrosinated octapeptide Red Pigment Concentrating Hormone (Tyr-RPCH). These are large neurons with diameters within a range of 33-43 microns and they were all positively st...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1006/gcen.1994.1143

    authors: Preciado M,Tsutsumi V,Aréchiga H

    更新日期:1994-09-01 00:00:00

  • Effects of vertebrate prolactins and growth hormones on thyroxine 5'-monodeiodination in the eel (Anguilla anguilla): a potential bioassay for growth hormone.

    abstract::Growth hormones (GHs) and prolactins (Prls) purified from representatives of each vertebrate class from bony fish onwards were tested for their ability to stimulate in vivo peripheral deiodination of labeled thyroxine (T4*) into triiodo-L-thyronine (T3*) in the eel. Plasma T3*/T4* ratio was used as parameter. All GHs ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(89)90091-9

    authors: de Luze A,Leloup J,Papkoff H,Kikuyama S,Kawauchi H

    更新日期:1989-02-01 00:00:00

  • Localization of mRNAs for a pair of prolactins and growth hormone in the Tilapia pituitary using in situ hybridization with oligonucleotide probes.

    abstract::Oligonucleotide probes were synthesized for the mRNAs of a pair of tilapia prolactins (tPRL177 and tPRL188) and growth hormone (tGH) based on cDNAs for the hormones of Oreochromis niloticus and amino acid sequences for the hormones of O. mossambicus. The three 45mer probes were labeled with 35S for hybridization studi...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1006/gcen.1993.1010

    authors: Nishioka RS,de Jesus EG,Hyodo S

    更新日期:1993-01-01 00:00:00

  • Circadian rhythms of thyroid secretion, morphometry, and cell division in prometamorphic and climax Rana tadpoles.

    abstract::Rhythmicity of thyroid follicle structure, cell division, and T4 secretion in vitro was studied in anuran tadpoles on a 12L:12D cycle with light onset at 0800 hr. Stage XIII Rana pipiens larvae had a significant circadian rhythm of follicle lumen diameter (acrophase 1052 hr). Follicle cell height was higher at 0900 hr...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1006/gcen.1995.1087

    authors: Wright ML,Blanchard LS,Pikula A,Labieniec KE

    更新日期:1995-07-01 00:00:00

  • Evidence for "short loop" feedback regulation of prolactin and growth hormone secretion in the pigeon.

    abstract::When pigeons were injected with an extract of chicken hypothalamus, the increase in weight of the crop sac showed that prolactin secretion was stimulated. Crop sac weight was no higher after 16 days of injection than it was after 8 days. Pituitary gland content of prolactin and growth hormone was elevated at 8 days, b...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(84)90106-0

    authors: Hall TR,Chadwick A

    更新日期:1984-08-01 00:00:00

  • Mapping the brain of the chicken (Gallus gallus), with emphasis on the septal-hypothalamic region.

    abstract::There has been remarkable progress in discoveries made in the avian brain, particularly over the past two decades. This review first highlights some of the discoveries made in the forebrain and credits the Avian Brain Nomenclature Forum, responsible for changing many of the terms found in the cerebrum and for stimulat...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygcen.2017.09.003

    authors: Kuenzel WJ

    更新日期:2018-01-15 00:00:00

  • Defining the contribution of select neuropeptides and their receptors in regulating sesquiterpenoid biosynthesis by Drosophila melanogaster ring gland/corpus allatum through RNAi analysis.

    abstract::The larval ring gland and adult corpus allatum (CA) of Drosophila melanogaster produce at least three sesquiterpenoid products: methyl farnesoate (MF), juvenile hormone III (JHIII), and JHIII bisepoxide (JHB(3)). Our understanding of neuropeptide regulation of sesquiterpenoid biosynthesis in D. melanogaster has been h...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2011.12.039

    authors: Wang C,Zhang J,Tobe SS,Bendena WG

    更新日期:2012-05-01 00:00:00

  • Salt intake and plasma renin activity in the freshwater turtle.

    abstract::In mammals, a well-documented inverse relationship exists between oral salt intake and plasma renin activity (PRA). We carried out this study to determine if a similar relationship exists in the freshwater turtle Pseudemys scripta. Three groups of turtles (N = 8 for each group) were fed different amounts of salt disso...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(89)90138-x

    authors: Stephens GA,Hauben D

    更新日期:1989-12-01 00:00:00

  • Real-time PCR analysis of cytochrome P450 aromatase expression in zebrafish: gene specific tissue distribution, sex differences, developmental programming, and estrogen regulation.

    abstract::In teleost fish, the predominant brain form of cytochrome P450 aromatase (P450aromB) is a neural marker of estrogen effect, and an entry point for studying the role of hormonal and environmental estrogens on neurodevelopment and neuroplasticity. As part of a project using zebrafish to investigate these issues, we deve...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2005.12.010

    authors: Sawyer SJ,Gerstner KA,Callard GV

    更新日期:2006-06-01 00:00:00

  • CCK-X receptors in the endothermic mako shark (Isurus oxyrinchus).

    abstract::By mapping the distribution of cholecystokinin (CCK) receptor types onto an established phylogenetic hypothesis of vertebrate relationships, we tested two hypothesis about the evolution of CCK receptors: (1) A single CCK receptor type, CCK-X, is the ancestral receptor, while CCK-A and CCK-B receptors represent derived...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1006/gcen.1996.0047

    authors: Oliver AS,Vigna SR

    更新日期:1996-04-01 00:00:00

  • Annual plasma testosterone and thyroxine cycles in relation to hibernation in the edible dormouse Glis glis.

    abstract::Twelve male edible dormice, captured in the autumn of 1979, were studied for 2 years under natural lighting in an animal enclosure with permanently open windows, at Montpellier, in Southern France (latitude 43 degrees 50' N). Ambient temperature fluctuated annually between +4 and 27 degrees, and the photoperiod betwee...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(83)90266-6

    authors: Jallageas M,Assenmacher I

    更新日期:1983-06-01 00:00:00

  • Testosterone influences song behaviour and social dominance - but independent of prenatal yolk testosterone exposure.

    abstract::In the last two decades, maternally derived yolk androgens have been shown to significantly alter offspring development, and a number of these effects persist into adulthood. However, little is known about their underlying mechanisms. Mechanisms that have been suggested are changes in the endogenous androgen productio...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2013.10.014

    authors: Vergauwen J,Groothuis TG,Eens M,Müller W

    更新日期:2014-01-01 00:00:00

  • Effects of chronic changes in dietary electrolytes and acute stress on plasma levels of corticosterone and aldosterone in the duck (Anas platyrhynchos).

    abstract::Plasma levels of corticosterone and aldosterone were determined by radioimmunoassay in ducks consuming diets containing different concentrations of sodium and potassium. Compared with control diet birds, maintenance on a high-Na+ diet for 5 days caused a 2-fold increase in the basal plasma corticosterone concentration...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(85)90131-5

    authors: Klingbeil CK

    更新日期:1985-04-01 00:00:00

  • Rearing conditions have long-term consequences for stress responsiveness in free-living great tits.

    abstract::In captivity, the adrenocortical stress response can be permanently altered by events that occur during early life. Free-living animals have rarely been examined in this regard. To examine whether early-life events impact the hypothalamo-pituitary-adrenal (HPA) axis in the natural setting, we evaluated the stress resp...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2011.08.022

    authors: Landys MM,Goymann W,Slagsvold T

    更新日期:2011-11-01 00:00:00

  • Chronically raised glucocorticoids reduce innate immune function in Belding's ground squirrels (Urocitellus beldingi) after an immune challenge.

    abstract::The hypothalamic-pituitary-adrenal (HPA) axis releases glucocorticoids (GCs), or stress hormones, during the vertebrate stress response. GCs can both enhance and suppress the immune system depending on whether the experienced stressor is acute or chronic and what aspect of immune function is measured. More research is...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2013.07.019

    authors: Brooks KC,Mateo JM

    更新日期:2013-11-01 00:00:00

  • Sexual bipotentiality of behavior in male and female goldfish.

    abstract::It is known that in goldfish Carassius auratus, a non-sex changing fish, prostaglandin (PG) treatment can induce female-typical sex behavior in males, and androgen treatment can induce male-typical sex behavior in females. These facts suggest that goldfish have a sexually bipotential brain even after attaining sexual ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2012.08.022

    authors: Saoshiro S,Kawaguchi Y,Hayakawa Y,Kobayashi M

    更新日期:2013-01-15 00:00:00

  • The presence of a pregnenolone-binding factor in the copulatory organ of the migratory locust, Locusta migratoria migratorioides R. & F.

    abstract::The presence of binding sites for nonecdysteroid steroids was investigated in the cytosol of several tissues of the migratory locust, Locusta migratoria migratorioides. Binding of androgens was not observed. Most tissues, however, showed nonsaturable binding of estrogens and in some tissues saturable progestin binding...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/0016-6480(88)90162-1

    authors: Paesen G,Novak F,Swevers L,De Clerck D,De Loof A

    更新日期:1988-12-01 00:00:00

  • Changes in plasma angiotensin II, aldosterone, arginine vasotocin, corticosterone, and electrolyte concentrations during acclimation to dry condition and seawater in the crab-eating frog.

    abstract::The crab-eating frog Fejervarya cancrivora inhabits mangrove swamps and marshes in Southeast Asia. In the present study, circulating angiotensin II (Ang II), aldosterone (Aldo), arginine vasotocin (AVT), and corticosterone (Cort) concentrations as well as various blood parameters were studied under osmotically stressf...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2013.10.013

    authors: Uchiyama M,Maejima S,Wong MK,Preyavichyapugdee N,Wanichanon C,Hyodo S,Takei Y,Matuda K

    更新日期:2014-01-01 00:00:00

  • Cloning of the gene and complete cDNA encoding a type 2 deiodinase from Fundulus heteroclitus.

    abstract::Recently, we reported the cloning of a cDNA fragment from Fundulus heteroclitus liver encoding the open reading frame of type 2 deiodinase (FhD2). We here report the cloning of 14 kb of genomic sequence from F. heteroclitus that includes the previously reported coding region of the F. heteroclitus Dio2 gene (FhDio2), ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/s0016-6480(02)00071-0

    authors: Orozco A,Jeziorski MC,Linser PJ,Greenberg RM,Valverde-R C

    更新日期:2002-09-01 00:00:00

  • Insights on the seasonal variations of reproductive features in the Eastern Atlantic Bluefin Tuna.

    abstract::The Atlantic Bluefin Tuna (ABFT, Thunnus thynnus) is one of the most intensely exploited fisheries resources in the world. In spite of the years of studies on ABFT, basic aspects of its reproductive biology remain uncertain. To gain insight regarding the seasonal changes of the reproductive characteristics of the east...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2019.113216

    authors: Carnevali O,Maradonna F,Sagrati A,Candelma M,Lombardo F,Pignalosa P,Bonfanti E,Nocillado J,Palma P,Gioacchini G,Elizur A

    更新日期:2019-10-01 00:00:00

  • Alternative splicing of the nuclear progestin receptor in a perciform teleost generates novel mechanisms of dominant-negative transcriptional regulation.

    abstract::In mammals, downstream function of the nuclear progestin receptor (PGR) can be differentially regulated in each target tissue by altering the expression levels of PGR mRNA variants. Such PGR isoforms have also been identified in birds and reptiles, but not in non-amniote vertebrates. Based upon extensive phylogenetic,...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2012.11.015

    authors: Zapater C,Chauvigné F,Fernández-Gómez B,Finn RN,Cerdà J

    更新日期:2013-02-01 00:00:00

  • Food, stress, and circulating testosterone: Cue integration by the testes, not the brain, in male zebra finches (Taeniopygia guttata).

    abstract::Food abundance is closely associated with reproductive readiness in vertebrates. Food scarcity can activate the hypothalamo-pituitary-adrenal axis, decrease sex steroid secretion, and dampen reproductive behavior. However, the mechanisms underlying these transient effects are unclear. Gonadotropin inhibitory hormone (...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2015.03.010

    authors: Lynn SE,Perfito N,Guardado D,Bentley GE

    更新日期:2015-05-01 00:00:00

  • Evolution of the sex-determining gene in the teleostean genus Oryzias.

    abstract::In the genetic sex determination of vertebrates, the gonadal sex depends on the combination of sex chromosomes that a zygote possesses. Despite the discovery of the sex-determining gene (SRY/Sry) in mammals in 1990s, the sex-determining gene in non-mammalian vertebrates remained an enigma for over a decade. In most ma...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章,评审

    doi:10.1016/j.ygcen.2015.10.004

    authors: Matsuda M,Sakaizumi M

    更新日期:2016-12-01 00:00:00

  • Glucose-dependent and -independent electrical activity in islets of Langerhans of Psammomys obesus, an animal model of nutritionally induced obesity and diabetes.

    abstract::Glucose-induced insulin secretion from pancreatic beta-cells involves metabolism-induced membrane depolarization and voltage-dependent Ca(2+) influx. The electrical events in beta-cell glucose sensing have been studied intensely using mouse islets of Langerhans, but data from other species, including models of type 2 ...

    journal_title:General and comparative endocrinology

    pub_type: 杂志文章

    doi:10.1016/j.ygcen.2008.12.017

    authors: Zimliki CL,Chenault VM,Mears D

    更新日期:2009-04-01 00:00:00