Family interventions for schizophrenia.

abstract：OBJECTIVE:To investigate patterns of mental health service and antipsychotic use following a first-episode schizophrenia (FES) and to examine the role of the treatment setting in which individuals are first diagnosed. METHOD:Analysis of de-identified administrative claims data from the OptumLabs Data Warehouse was use...

journal_title：Schizophrenia bulletin

authors： Gilmer TP,van der Ven E,Susser E,Dixon LB,Olfson M

更新日期：2020-01-04 00:00:00

abstract：:The aim of the study was to evaluate the latent structure of DSM-IV schizotypal personality disorder (SPD) diagnostic criteria. The sample consisted of 564 consecutively admitted inpatients and outpatients. Exploratory latent class analysis identified a four-class model as the best fitting model for DSM-IV SPD criteri...

journal_title：Schizophrenia bulletin

authors： Fossati A,Maffei C,Battaglia M,Bagnato M,Donati D,Donini M,Fiorilli M,Novella L

更新日期：2001-01-01 00:00:00

abstract：:A substantial amount of research has focused on the midbrain dopamine system and its role in emotional and motivational behaviors. In diseases in which dopamine function is compromised, patients exhibit a constellation of symptoms, suggesting that the dopamine system plays an important role in the integration of sever...

journal_title：Schizophrenia bulletin

authors： Haber SN,Fudge JL

更新日期：1997-01-01 00:00:00

abstract：:In subjects at risk for psychosis, the studies on gray matter volume (GMV) predominantly reported volume loss compared with healthy controls (CON). However, other important morphological measurements such as cortical surface area (CSA) and cortical thickness (CT) were not systematically compared. So far, samples mostl...

journal_title：Schizophrenia bulletin

authors： Buechler R,Wotruba D,Michels L,Theodoridou A,Metzler S,Walitza S,Hänggi J,Kollias S,Rössler W,Heekeren K

更新日期：2020-12-01 00:00:00

abstract：:Schizophrenia elevates the risk for aggressive behavior and violent crime, and different approaches have been used to manage this problem. The results of such treatments vary. One reason for this variation is that aggressive behavior in schizophrenia is heterogeneous in origin. This heterogeneity has usually not been ...

journal_title：Schizophrenia bulletin

authors： Volavka J,Citrome L

更新日期：2011-09-01 00:00:00

abstract：:One of the leading theories of the neuropathology of schizophrenia is that it is a developmental disorder of "neural connectivity." To assess this theory, it is first necessary to understand how precise neural connections normally are established. Sensory-driven neural activity has been widely recognized as crucial fo...

journal_title：Schizophrenia bulletin

authors： Penn AA

更新日期：2001-01-01 00:00:00

abstract：:This article combines a review and meta-analysis of research on IQ in schizophrenia, with emphasis on areas of convergence in the findings, as well as questions that remain to be answered. Taken together, the findings suggest that early-onset and adult-onset schizophrenia are associated with intellectual deficits acro...

journal_title：Schizophrenia bulletin

authors： Aylward E,Walker E,Bettes B

更新日期：1984-01-01 00:00:00

abstract：:Social networks of 35 mentally ill persons were studied in Lao villages. Mental illness was associated with a decrease in size of social networks, disproportionate reliance on family, and asymmetric instrumental exchange. Nonkin "sponsors" provided assistance to those alienated from or abandoned by relatives. For thos...

journal_title：Schizophrenia bulletin

authors： Westermeyer J,Pattison EM

更新日期：1981-01-01 00:00:00

abstract：:The left superior temporal sulcus (STS) plays an important role in integrating audiovisual information and is functionally connected to disparate regions of the brain. For the integration of gesture information in an abstract sentence context (metaphoric gestures), intact connectivity between the left STS and the infe...

journal_title：Schizophrenia bulletin

authors： Straube B,Green A,Sass K,Kircher T

更新日期：2014-07-01 00:00:00

abstract：:Identifying predictors and elucidating the fundamental mechanisms underlying onset of psychosis are critical for the development of targeted preemptive interventions. This article presents a selective review of findings on risk prediction algorithms and potential mechanisms of onset in youth at clinical high-risk for ...

journal_title：Schizophrenia bulletin

authors： Cannon TD

更新日期：2016-07-01 00:00:00

abstract：:Cognitive remediation improves cognition in patients with schizophrenia, but its effect on other relevant factors such as negative symptoms and functional outcome has not been extensively studied. In this hospital-based study, 84 inpatients with chronic schizophrenia were recruited from Alava Hospital (Spain). All of ...

journal_title：Schizophrenia bulletin

authors： Sánchez P,Peña J,Bengoetxea E,Ojeda N,Elizagárate E,Ezcurra J,Gutiérrez M

更新日期：2014-05-01 00:00:00

abstract：Objective:Evidence suggests that social skills training (SST) is an efficacious intervention for negative symptoms in psychosis, whereas evidence of efficacy in other psychosis symptom domains is limited. The current article reports a comprehensive meta-analytic review of the evidence for SST across relevant outcome me...

journal_title：Schizophrenia bulletin

authors： Turner DT,McGlanaghy E,Cuijpers P,van der Gaag M,Karyotaki E,MacBeth A

更新日期：2018-04-06 00:00:00

abstract：:The causal mechanism underlying the well-established relation between advancing paternal age and schizophrenia is hypothesized to involve mutational errors during spermatogenesis that occur with increasing frequency as males age. Point mutations are well known to increase with advancing paternal age while other errors...

journal_title：Schizophrenia bulletin

authors： Perrin MC,Brown AS,Malaspina D

更新日期：2007-11-01 00:00:00

abstract：:Research into tardive dyskinesia, an involuntary movement disorder secondary to chronic neuroleptic treatment, has so far produced conflicting results with no clear clinical applications. Heterogeneous diagnostic criteria, research designs, and rating scales, plus an emphasis on single-drug trials, are probably respon...

journal_title：Schizophrenia bulletin

authors： Nasrallah HA

更新日期：1979-01-01 00:00:00

abstract：:Schizophrenia is a disorder of a neurodevelopmental origin manifested symptomatically after puberty. Structural neuroimaging studies show that neuroanatomical aberrations precede onset of symptoms, raising a question of whether schizophrenia can be prevented. Early treatment with atypical antipsychotics may reduce the...

journal_title：Schizophrenia bulletin

authors： Piontkewitz Y,Arad M,Weiner I

更新日期：2011-11-01 00:00:00

abstract：:Between 5% and 10% of people with psychosis will die by suicide, a rate which is 20-75 times higher than the general population. This risk is even greater in those not taking antipsychotic medication. We examined whether negative appraisals of psychotic experiences and negative metacognitive beliefs about losing menta...

journal_title：Schizophrenia bulletin

authors： Hutton P,Di Rienzo F,Turkington D,Spencer H,Taylor P

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Similar to patients with other chronic disorders, patients with serious mental illness (SMI) are often poorly adherent with prescribed medications. OBJECTIVE:We conducted a randomized controlled trial examining the effectiveness of a pharmacy-based intervention (Meds-Help) in increasing antipsychotic medica...

journal_title：Schizophrenia bulletin

authors： Valenstein M,Kavanagh J,Lee T,Reilly P,Dalack GW,Grabowski J,Smelson D,Ronis DL,Ganoczy D,Woltmann E,Metreger T,Wolschon P,Jensen A,Poddig B,Blow FC

更新日期：2011-07-01 00:00:00

abstract：:The diagnosis of schizophrenia is thought to embrace several distinct subgroups. The manifold entities in a single clinical patient group increase the variance of biological measures, deflate the group-level estimates of causal factors, and mask the presence of treatment effects. However, reliable neurobiological boun...

journal_title：Schizophrenia bulletin

authors： Pan Y,Pu W,Chen X,Huang X,Cai Y,Tao H,Xue Z,Mackinley M,Limongi R,Liu Z,Palaniyappan L

更新日期：2020-04-10 00:00:00

abstract：:Schizophrenia is a chronic brain disorder that affects about 1.1% of the adult US population annually. Hallucinations, delusions, and impaired reality testing are prominent symptoms of the disorder. Modeling these symptoms is difficult because it is unclear how to assess impaired reality testing in animals. Animals ca...

journal_title：Schizophrenia bulletin

authors： McDannald M,Schoenbaum G

更新日期：2009-07-01 00:00:00

abstract：:The prodrome of psychosis has become a target for early identification and for treatments that address both symptoms and risk for future psychosis. Interest and activity in this realm is now worldwide. Clinical trials with rigorous methodology have only just begun, making treatment guidelines premature. Despite the sp...

journal_title：Schizophrenia bulletin

authors： McGlashan TH,Addington J,Cannon T,Heinimaa M,McGorry P,O'Brien M,Penn D,Perkins D,Salokangas RK,Walsh B,Woods SW,Yung A

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:Both neurocognitive impairments and a history of childhood abuse are highly prevalent in patients with schizophrenia. Childhood trauma has been associated with memory impairment as well as hippocampal volume reduction in adult survivors. The aim of the following study was to examine the contribution of childh...

journal_title：Schizophrenia bulletin

authors： Shannon C,Douse K,McCusker C,Feeney L,Barrett S,Mulholland C

更新日期：2011-05-01 00:00:00

abstract：:Recent advances in functional genomics have facilitated the identification of multiple genes and isoforms associated with the genetic risk of schizophrenia, yet the causal variations remain largely unclear. A previous study reported that the schizophrenia risk single-nucleotide polymorphism (SNP) rs7085104 at 10q24.32...

journal_title：Schizophrenia bulletin

authors： Cai X,Yang ZH,Li HJ,Xiao X,Li M,Chang H

更新日期：2021-01-23 00:00:00

abstract：BACKGROUND:The at-risk mental state for psychosis (ARMS) and the first episode of psychosis have been associated with structural brain abnormalities that could aid in the individualized early recognition of psychosis. However, it is unknown whether the development of these brain alterations predates the clinical deteri...

journal_title：Schizophrenia bulletin

authors： Borgwardt S,Koutsouleris N,Aston J,Studerus E,Smieskova R,Riecher-Rössler A,Meisenzahl EM

更新日期：2013-09-01 00:00:00

abstract：:This article focuses on the cross-modal reaction time paradigm, which has been used to study deviation patterns of shifting attention across stimulus modalities in schizophrenic patients. Cross-modal reaction time research involving pathological and nonpathological populations is reviewed. The influence of sex, stimul...

journal_title：Schizophrenia bulletin

authors： Mannuzza S

更新日期：1980-01-01 00:00:00

abstract：BACKGROUND:Executive control of attention in schizophrenia has recently been assessed by means of the Attention Network Test (ANT). In the past, for tasks assessing executive attention, findings in schizophrenia have been contradictory, among others suggesting a lack of increased stimulus interference effects. Attentio...

journal_title：Schizophrenia bulletin

authors： Opgen-Rhein C,Neuhaus AH,Urbanek C,Hahn E,Sander T,Dettling M

更新日期：2008-11-01 00:00:00

abstract：:Methodological issues involved in assessing the prevalence of substance abuse in schizophrenia are discussed, and previous research in this area is comprehensively reviewed. Many studies suffer from methodological shortcomings, including the lack of diagnostic rigor, adequate sample sizes, and simultaneous assessment ...

journal_title：Schizophrenia bulletin

authors： Mueser KT,Yarnold PR,Levinson DF,Singh H,Bellack AS,Kee K,Morrison RL,Yadalam KG

更新日期：1990-01-01 00:00:00

abstract：:Although glutamate was first hypothesized to be involved in the pathophysiology of schizophrenia in the 1980s, it was the demonstration that N-methyl-D-aspartate (NMDA) receptor antagonists, the dissociative anesthetics, could replicate the full range of psychotic, negative, cognitive, and physiologic features of schi...

journal_title：Schizophrenia bulletin

authors： Coyle JT

更新日期：2012-09-01 00:00:00

abstract：:Psychophysiological anomalies in symptomatic schizophrenic patients, remitted schizophrenic patients, and individuals at heightened risk for a schizophrenic disorder are reviewed with an emphasis on electrodermal anomalies. Two electrodermal anomalies are identified in different subgroups of symptomatic patients: (1) ...

journal_title：Schizophrenia bulletin

authors： Dawson ME,Nuechterlein KH

更新日期：1984-01-01 00:00:00

abstract：:Research on the effectiveness of short-term education programs in changing societal attitudes about mental illness has been mixed. Education efforts seem to be mediated by characteristics of the program participants. This study determines whether the effects of a specially prepared, semester-long course on severe ment...

journal_title：Schizophrenia bulletin

authors： Holmes EP,Corrigan PW,Williams P,Canar J,Kubiak MA

更新日期：1999-01-01 00:00:00

abstract：:This study tested hypothesized relationships between neuropsychological and psychophysiological variables and concurrent levels of clinical and psychosocial functioning in schizophrenia. The sample consisted of 40 subjects diagnosed with a chronic schizophrenia spectrum disorder and living in community-based settings....

journal_title：Schizophrenia bulletin

authors： Brekke JS,Raine A,Ansel M,Lencz T,Bird L

更新日期：1997-01-01 00:00:00