Abstract:
:A combination of Southern blot analysis on a panel of tumor-derived somatic cell hybrids and fluorescence in situ hybridization (FISH) techniques was used to map a series of DNA markers relative to the 1q21 breakpoint of the renal cell carcinoma (RCC)-associated (X;1)-(p11;q21) translocation. This breakpoint maps between several members of the S100 family which are clustered in the 1q21 region and a conserved region between man and mouse containing the markers SPTA1-CRP-APCS-FcER1A-ATP1A2-APOA2. The location of the breakpoint coincides with the transition of a region of synteny of human chromosome 1 with mouse chromosomes 3 and 1.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Weterman MA,Wilbrink M,Dijkhuizen T,van den Berg E,Geurts van Kessel Adoi
10.1007/s004390050153subject
Has Abstractpub_date
1996-07-01 00:00:00pages
16-21issue
1eissn
0340-6717issn
1432-1203journal_volume
98pub_type
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