Abstract:
:A series of 195 random chromosome 22-specific probes, equivalent to approximately 1% of the size of this chromosome, have been isolated from a chromosome 22-specific bacteriophage lambda genomic library. These probes were mapped to four different regions of chromosome 22 on a panel of five somatic cell hybrids. Restriction fragment length polymorphisms were detected by 28 of the probes mapping to 22q12-qter. Evolutionarily conserved sequences in human, mouse, and Chinese hamster DNA were detected by 12% of the isolated probes.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Dumanski JP,Geurts van Kessel AH,Ruttledge M,Wladis A,Sugawa N,Collins VP,Nordenskjöld Mdoi
10.1007/BF00200562subject
Has Abstractpub_date
1990-02-01 00:00:00pages
219-22issue
3eissn
0340-6717issn
1432-1203journal_volume
84pub_type
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