Abstract:
:To improve the analysis of parentage testing with the additional technique of DNA polymorphisms, the usefulness of probe YNH24 was studied. The allele frequency distribution of restriction fragments detected by probe YNH24 on TaqI-digested genomic DNA from 100 unrelated individuals was determined. For this purpose, the size of the fragments was calculated by making use of HindIII-digested lambda DNA as an internal marker and of a digitizing tablet coupled to a computer. The size of the fragments ranged from 2.53 kb to 5.89 kb. The mean standard deviation was 0.05 kb. The differences between the fragment sizes appeared to be smaller than the standard deviation. For this reason, it was not possible to calculate the allele frequency distribution of this highly polymorphic genetic system.
journal_name
Hum Genetjournal_title
Human geneticsauthors
van Eede PH,Cuypers TM,de Lange GGdoi
10.1007/BF00196240subject
Has Abstractpub_date
1990-03-01 00:00:00pages
376-8issue
4eissn
0340-6717issn
1432-1203journal_volume
84pub_type
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