Abstract:
:Rearranged human chromosomes carrying segments of chromosome 11 were separated from the normal chromosome 11 by high-resolution chromosome sorting. Sorted chromosomes were tested with parathyroid hormone, beta-globin, insulin, and LDH-A gene-specific probes to determine the genes carried by each chromosome segment. Based on the gene content and karyotypes of these abnormal chromosomes, the parathyroid hormone, beta-globin, insulin, and LDH-A genes and the unique restriction fragment ADJ-762 are all located on the terminal band of the short arm of human chromosome 11 (band 11p15), with LDH-A proximal to the other loci.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Lebo RV,Cheung MC,Bruce BD,Riccardi VM,Kao FT,Kan YWdoi
10.1007/BF00291648subject
Has Abstractpub_date
1985-01-01 00:00:00pages
316-20issue
4eissn
0340-6717issn
1432-1203journal_volume
69pub_type
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