Abstract:
:Steroid sulfatase activities are significantly higher in placentas obtained after the birth of girls than after the birth of boys, and also in female fibroblasts compared to male strains. This constitutes biochemical evidence for the non-inactivation of the X-linked sulfatase locus. No hydrolytic activity is found in the fibroblasts of ichthyotic boys. Heterozygosity is demonstrated in the fibroblasts of the four mothers studied, as they have steroid sulfatase activity of less or equivalent to the normal male value.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Bedin M,Weil D,Fournier T,Cedard L,Frezal Jdoi
10.1007/BF00283675subject
Has Abstractpub_date
1981-01-01 00:00:00pages
256-8issue
3eissn
0340-6717issn
1432-1203journal_volume
59pub_type
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