Abstract:
:The gene locus for hereditary retinoblastoma is on human chromosome 13, band q14. With this gene localization in mind, we cloned DNA fragments from this chromosome. Three of the fragments identify restriction fragment length polymorphisms. These three fragments are from the region 13q12-13q22, the chromosome region which contains the retinoblastoma locus. We expect that these restriction fragment length polymorphisms will be linked to the retinoblastoma locus, and that they will serve in certain retinoblastoma families as predictors of retinoblastoma gene carriers. They will also be useful in studies of other gene loci thought to be on chromosome 13.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Dryja TP,Rapaport JM,Weichselbaum R,Bruns GAdoi
10.1007/BF00291555subject
Has Abstractpub_date
1984-01-01 00:00:00pages
320-4issue
4eissn
0340-6717issn
1432-1203journal_volume
65pub_type
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