Abstract:
:The delta F508 mutation and cystic fibrosis (CF) haplotypes with the markers KM19, pMP6d-9 and J3.11 are described in 54 adult British CF patients. delta F508 was found on 70% of all CF chromosomes, on none of the normal chromosomes and on only 37.5% of pancreatic sufficient CF chromosomes. All patients with meconium ileus were homozygous for the deletion.
journal_name
Hum Genetjournal_title
Human geneticsauthors
Santis G,Osborne L,Knight R,Ramsay M,Williamson R,Hodson Mdoi
10.1007/BF02428295subject
Has Abstractpub_date
1990-09-01 00:00:00pages
424-5issue
4eissn
0340-6717issn
1432-1203journal_volume
85pub_type
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