Abstract:
:This pre-embedding electron-immunocytochemical study investigated the localisation of endothelial (type III) and neuronal (type I) isoforms of nitric oxide synthase, substance P, endothelin-1 and 5-hydroxytryptamine in the human middle cerebral artery taken up to 40 h postmortem. To ¿recover' from the anoxic period some of the vessels were incubated in oxygenated Krebs solution prior to the immunoprocedure. At this long postmortem time, immunoreactivity to type III and type I nitric oxide synthase, substance P, endothelin-1 and 5-hydroxytryptamine was found in a subpopulation of intact cells present in the vessel intima; immunoreactivity to type I nitric oxide synthase was also observed in a subpopulation of adventitial perivascular nerve fibres. Cultures of the cells from the intima of the postmortem vessels showed that the cells were proliferating and positive immunoreactivity to factor VII identified them as endothelial cells. The results therefore indicate that even after up to 40 h postmortem, endothelium of human middle cerebral artery is immunoreactive for a number of vasoactive agents and perivascular nerve fibres show nitric oxide synthase immunoreactivity.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Gorelova E,Loesch A,Bodin P,Chadwick L,Hamlyn PJ,Burnstock Gsubject
Has Abstractpub_date
1996-02-01 00:00:00pages
97-107eissn
0021-8782issn
1469-7580journal_volume
188 ( Pt 1)pub_type
杂志文章abstract::Excisional wounds were inflicted on the palatal mucoperiosteum of beagle pups at intervals from 3 to 31 days before the animals were killed, when the animals were perfused and the tissue examined by electron, microscopy. Fibroblasts with the morphological characteristics of myofibroblasts, including bundles of intrace...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1980-05-01 00:00:00
abstract::A histological study has shown that considerable amounts of lipid accumulate in the oxyntico-peptic cells of the proventriculus of domestic fowls deprived of food. Lipid droplets were first seen in the cells 6 hours after commencing the fast and they reached a maximum in 24 hours; a decrease was detected histologicall...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-12-01 00:00:00
abstract::The pulmonary intravascular macrophages (PIMs) of domestic ungulates are recognised by their specific surface coat, consisting of linearly arranged globules along the external leaf of the plasma membrane. The coat is sensitive to in vitro digestion with lipolytic lipase (LPL), intravenous heparin and clinical exposure...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19850611.x
更新日期:2001-05-01 00:00:00
abstract::Peripheral sensory and autonomic neurons are known to possess insulin receptors. These have been considered to be of the peripheral type, i.e. similar to those of hepatic and fat cells rather than of the brain type which show dual specificity for both insulin and insulin-like growth factor (IGF-1). We have examined th...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19130431.x
更新日期:1997-10-01 00:00:00
abstract::The proximal stump of the optic nerve was examined by electron microscopy from 1 d to 8 wk (dpo/wpo) after intraorbital transection. At 1 dpo a layer of axonal, cytoplasmic and myelin debris approximately 15 microns thick was present at the cut end. A zone approximately 25 microns thick of abnormal and partly degenera...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::The neuromuscular junction (NMJ) is the highly specialised peripheral synapse formed between lower motor neuron terminals and muscle fibres. Post-synaptic acetylcholine receptors (AChRs), which are found in high density in the muscle membrane, bind to acetylcholine released into the synaptic cleft of the NMJ, thereby ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13228
更新日期:2020-10-01 00:00:00
abstract::The rete testis in the domestic fowl (Gallus gallus domesticus), Japanese quail (Coturnix coturnix japonica), guinea-fowl (Numida meleagris galeata) and drake (Anas platyrhynchos) was studied histologically and with both the scanning and transmission electron microscopes. All the birds have rete epithelial cells varyi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::The study of human anatomy can be found throughout the rich history of Persia. For thousands of years, morphological descriptions derived from this part of the world have contributed to and have helped form our current anatomical knowledge base. In this article we review the major influential Persian periods and the i...
journal_title:Journal of anatomy
pub_type: 历史文章,杂志文章
doi:10.1111/j.1469-7580.2007.00711.x
更新日期:2007-04-01 00:00:00
abstract::The T-tubule system in cardiac muscle cells has been investigated with the electron microscope in 10 adult rats after infiltration with horseradish peroxidase. All cardiac muscle cells possess a T-system, but its complexity varies according to the region of the heart. It is most extensive in the general ventricular my...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1978-09-01 00:00:00
abstract::Comb and wattle tissues, which consist of layers of epidermis, dermis and central connective tissue, are known to contain sulphated glycosaminoglycans (GAGs) including dermatan sulphate and chondroitin sulphate-dermatan sulphate copolymers. Little is known about distribution of these CAGs in each tissue. The objective...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1996-12-01 00:00:00
abstract::Amoeboid microglial cells (AMC) in the corpus callosum were selectively labelled following a single intraperitoneal (i.p.) injection of the fluorescent dye, rhodamine isothiocyanate (RhIc) into postnatal rats. The frequency of RhIc-labelled cells varied with age, with the largest number occurring in 7-d-old animals. T...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::Fascia in the veterinary sciences is drawing attention, such that physiotherapists and animal practitioners are now applying techniques based on the concept of fascia studies in humans. A comprehensive study of fascia is therefore needed in animals to understand the arrangement of the fascial layers in an unguligrade ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13064
更新日期:2019-12-01 00:00:00
abstract::Wheat germ agglutinin-horseradish peroxidase conjugate (WGA-HRP) was injected into the dorsal root ganglia (L5-S1) of the cat and used as an anterograde tracer substance for intra-axonal labelling of peripheral nerve endings in joint capsule and cranial (anterior) cruciate ligament (CCL). We believed that the high spe...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1997.19020289.x
更新日期:1997-02-01 00:00:00
abstract::Human beings have considerably expanded cognitive abilities compared with all other species and they also have a relatively larger cerebral cortex compared with their body size. But is a bigger brain the only reason for higher cognition or have other features evolved in parallel? Humans have more and different types o...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/joa.12198
更新日期:2015-10-01 00:00:00
abstract::Mouse immunoglobulin G (IgG) was iodinated with 125iodine (I) and injected intravenously into pregnant mice in order to examine whether mouse granulated metrial gland (GMG) cells are able to take up IgG in vivo. The mice were injected intravenously on days 8, 12 or 16 of pregnancy and killed either 5 min, 2 h or 24 h ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract::The main aim of the present work is to synthesize the information obtained from our dissections of the pectoral and forelimb muscles of representative members of the major extant taxa of limbed amphibians and reptiles and from our review of the literature, in order to provide an account of the comparative anatomy, hom...
journal_title:Journal of anatomy
pub_type: 杂志文章,评审
doi:10.1111/j.1469-7580.2010.01278.x
更新日期:2010-11-01 00:00:00
abstract::The aim of the study was to examine by means of stereology the effects of pinealectomy and melatonin on the structure of the adrenal cortex of ovariectomised rats and to check whether the effect of oestradiol on the rat adrenal cortex is modified by the pineal gland. Neither pinealectomy (73 days) nor melatonin treatm...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
abstract::Non-ionic, low-osmolar contrast agents (CAs) used for computed tomography, such as Optiray (ioversol) and Iomeron (iomeprol), are associated with the reduced risk of adverse reactions and toxicity in comparison with ionic CAs, such as Hexabrix. Hexabrix has previously been used for imaging articular cartilage but has ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.13271
更新日期:2020-12-01 00:00:00
abstract::Muscle moment arms were measured for major muscles of the pelvic limb of the ostrich (Struthio camelus) in order to assess specific functional behaviour and to apply this to locomotor performance. Pelvic limbs of six juvenile ostriches were used for this study. The tendon travel technique was used to measure moment ar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00762.x
更新日期:2007-09-01 00:00:00
abstract::A quantitative comparison of the internal diameters of cerebral feeder arteries (internal carotid and vertebral) and the aorta in developing non-human eutherians, metatherians and monotremes has been made, with the aim of determining if there are differences in cerebral arterial flow between the three infraclasses of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/joa.12422
更新日期:2016-03-01 00:00:00
abstract::The structure of the cardiac foramen ovale from 17 species representing six cetacean families, the Monodontidae, Phocoenidae, Delphinidae, Ziphiidae, Balaenidae and the Balaenopteridae, was studied using the scanning electron microscope. Eight white whale fetuses (Delphinapterus leucas) and a narwhal fetus (Monodon mo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.1469-7580.2007.00743.x
更新日期:2007-07-01 00:00:00
abstract::Fertilised chicken eggs were incubated for 48 hours while exposed to pulsed trains of magnetic fields having a duration of 0-5 ms, a rise time of 42 microsecond, and a pulse repetition rate of 100 at a magnetic field flux density of 1 microT. Some eggs were exposed to 1,552 rad X-rays as a positive control. After expo...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1988-04-01 00:00:00
abstract::Lateral nasal glands of 12-15 weeks old pups are immature. Gland acini of pups and mature dogs contain numerous electron-lucent vacuoles with basophilic, electron-dense cores. The vacuoles contain both acid and neutral glycoproteins, sialated glycoproteins being the dominant acidic moiety. Lateral and basal cytoplasmi...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Histochemical fibre types classified in sections stained for succinic dehydrogenase (sdh) and myosin ATPase at pH 9.4, were found to be distributed in a consistent manner within the extensor digitorum longus (EDL) and 4 soleus muscles of the adult rat. Simple morphometric techniques applied to complete transverse sect...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1977-04-01 00:00:00
abstract::The dentate nucleus is phylogenetically the most recent nucleus in the cerebellum. Owing to its connections to the thalamus and the prefrontal cortex it may be involved in the symptomathology in schizophrenia and other psychiatric illnesses. In this stereological study we implemented the smooth fractionator, which com...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1111/j.0021-8782.2004.00337.x
更新日期:2004-10-01 00:00:00
abstract::It is currently thought that New World monkeys, prosimians, and humans are the only primates to possess vomeronasal organs (VNOs) as adults. Recent studies of the human VNO suggest that previous investigations on Old World primates may have missed the VNO. We examined nasal septa from the chimpanzee (Pan troglodytes) ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.2001.19810077.x
更新日期:2001-01-01 00:00:00
abstract::The Harderian gland, its secretory duct and porphyrin content were examined in the mongolian gerbil (Meriones unguiculatus). The gland consisted of tubules lined by a single layer of epithelial cells and a myoepithelial network. The tubule cells were often binucleate and possessed lipid vacuoles in the apical half of ...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1983-10-01 00:00:00
abstract::A study of the attachments of the musculotendinous fibres of the lumbar erector spinae muscle shows that it is made of two parts: a superficial or costal part, and a deep or vertebral part. The superficial part arises by small fleshy slips from the posterior (superficial) surface as well as the rostral and lateral mar...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1986-02-01 00:00:00
abstract::The total numbers of fibres in transverse histological sections of the pterygoid muscles of Lister rats of various ages were counted on enlarged photomicrographic prints. The number in the medial pterygoid of the male doubled between birth and six weeks. This was followed by a decrease of rather more than 10 percent i...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:
更新日期:1975-04-01 00:00:00
abstract::The distribution of mRNAs and antigens of tissue type (t) and urokinase type (u) plasminogen activators (PA) plus their corresponding inhibitors, type-1 (PAI-1) and type-2 (PAI-2) were studied in human and rhesus monkey placentae by in situ hybridisation and immunocytochemistry. Specific monkey cRNA and antibodies aga...
journal_title:Journal of anatomy
pub_type: 杂志文章
doi:10.1046/j.1469-7580.1999.19420183.x
更新日期:1999-02-01 00:00:00