An enhanced role and expanded developmental origins for gamma-aminobutyric acidergic interneurons in the human cerebral cortex.

Abstract:

:Human beings have considerably expanded cognitive abilities compared with all other species and they also have a relatively larger cerebral cortex compared with their body size. But is a bigger brain the only reason for higher cognition or have other features evolved in parallel? Humans have more and different types of GABAergic interneurons, found in different places, than our model species. Studies are beginning to show differences in function. Is this expanded repertoire of functional types matched by an evolution of their developmental origins? Recent studies support the idea that generation of interneurons in the ventral telencephalon may be more complicated in primates, which have evolved a large and complex outer subventricular zone in the ganglionic eminences. In addition, proportionally more interneurons appear to be produced in the caudal ganglionic eminence, the majority of which populate the superficial layers of the cortex. Whether or not the cortical proliferative zones are a source of interneurogenesis, and to what extent and of what significance, is a contentious issue. As there is growing evidence that conditions such as autism, schizophrenia and congenital epilepsy may have developmental origins in the failure of interneuron production and migration, it is important we understand fully the similarities and differences between human development and our animal models.

journal_name

J Anat

journal_title

Journal of anatomy

authors

Clowry GJ

doi

10.1111/joa.12198

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

384-93

issue

4

eissn

0021-8782

issn

1469-7580

journal_volume

227

pub_type

杂志文章,评审
  • Phagocytic capacity of leucocytes in sheep mammary secretions following weaning.

    abstract::Lactating animals are particularly susceptible to mastitis during the early stages of mammary gland involution following weaning. In this study we compared the phagocytic capacity of cells collected from sheep mammary secretions at different stages of involution. The ability of neutrophils and macrophages to ingest la...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.0021-8782.2002.00104.x

    authors: Tatarczuch L,Bischof RJ,Philip CJ,Lee CS

    更新日期:2002-11-01 00:00:00

  • Gross and microscopic visceral anatomy of the male Cape fur seal, Arctocephalus pusillus pusillus (Pinnipedia: Otariidae), with reference to organ size and growth.

    abstract::The gross and microscopic anatomy of the Cape fur seal heart, lung, liver, spleen, stomach, intestine and kidneys (n = 31 seals) is described. Absolute and relative size of organs from 30 male seals are presented, with histological examination conducted on 7 animals. The relationship between log body weight, log organ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.1999.19520235.x

    authors: Stewardson CL,Hemsley S,Meyer MA,Canfield PJ,Maindonald JH

    更新日期:1999-08-01 00:00:00

  • The development of Schmidt-Lanterman incisures: an electron microscope study.

    abstract::The development of Schmidt-Lanterman incisures was investigated in the rat sural nerve during an active phase of postnatal myelination (5-21 days post partum). Two distinct populations of incisures were recognised and the following nomenclature for their developmental stages is proposed. Primary incisures which appear...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Small JR,Ghabriel MN,Allt G

    更新日期:1987-02-01 00:00:00

  • Expression of extracellular matrix molecules typical of articular cartilage in the human scapholunate interosseous ligament.

    abstract::The scapholunate interosseous ligament (SLIL) connects the scaphoid and lunate bones and plays a crucial role in carpal kinematics. Its rupture leads to carpal instability and impairment of radiocarpal joint function. As the ligament is one of the first structures affected in rheumatoid arthritis, we conducted an immu...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/j.1469-7580.2006.00552.x

    authors: Milz S,Aktas T,Putz R,Benjamin M

    更新日期:2006-06-01 00:00:00

  • RT97- and calcitonin gene-related peptide-like immunoreactivity in lumbar intervertebral discs and adjacent tissue from the rat.

    abstract::The innervation of rat intervertebral disc and adjacent ligamentous tissue has been investigated using 2 antibodies, RT97 and anti-calcitonin gene-related peptide. Immunoreactivity to the peptide was found in many fibres throughout the long ligaments around the intervertebral discs and in the periosteum, especially as...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: McCarthy PW,Petts P,Hamilton A

    更新日期:1992-02-01 00:00:00

  • A confocal and conventional epifluorescence microscope study of the intermediate filaments in chorionic villi.

    abstract::An immuno-epifluorescence microscopic study of first trimester human chorionic villi has revealed different patterns of distribution for intermediate filament proteins. Keratin staining was restricted to the trophoblastic epithelium. The protein was shown to be concentrated into desmosome-containing apical and basal c...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Bradbury FM,Ockleford CD

    更新日期:1990-04-01 00:00:00

  • The missing segment of the autopod 1st ray: new insights from a morphometric study of the human hand.

    abstract::Whether the 1st segment of the human autopod 1st ray is a 'true' metapodial with loss of the proximal or mid phalanx or the original basal phalanx with loss of the metacarpal has been a long-lasting discussion. The actual knowledge of the developmental pattern of upper autopod segments at a fetal age of 20-22 weeks, c...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/joa.12883

    authors: Pazzaglia UE,Sibilia V,Casati L,Salvi AG,Minini A,Reguzzoni M

    更新日期:2018-12-01 00:00:00

  • Characterization of the annulus fibrosus-vertebral body interface: identification of new structural features.

    abstract::Current surgical treatments for degenerative intervertebral disc disease do not restore full normal spinal movement. Tissue engineering a functional disc replacement may be one way to circumvent this limitation, but will require an integration of the different tissues making up the disc for this approach to be success...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/j.1469-7580.2012.01537.x

    authors: Nosikova YS,Santerre JP,Grynpas M,Gibson G,Kandel RA

    更新日期:2012-12-01 00:00:00

  • The distribution and relative sized of fibre types in the extensor digitorum longus and soleus muscles of the adult rat.

    abstract::Histochemical fibre types classified in sections stained for succinic dehydrogenase (sdh) and myosin ATPase at pH 9.4, were found to be distributed in a consistent manner within the extensor digitorum longus (EDL) and 4 soleus muscles of the adult rat. Simple morphometric techniques applied to complete transverse sect...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Pullen AH

    更新日期:1977-04-01 00:00:00

  • An ultrastructural study of cartilage resorption at the site of initial endochondral bone formation in the fetal mouse mandibular condyle.

    abstract::An ultrastructural study was undertaken on cartilage resorption at the site of initial endochondral bone formation in the mouse mandibular condyle on d 16 of pregnancy. After resorbing the bone collar, the osteoclasts extended their cell processes into the cartilage matrix and made contact with hypertrophic chondrocyt...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.1997.19110065.x

    authors: Shibata S,Suzuki S,Yamashita Y

    更新日期:1997-07-01 00:00:00

  • Trigeminal nerve pathways to the cerebral arteries in monkeys.

    abstract::Two or three or sometimes more fine intracavernous branches were traced from the ophthalmic nerve using serial section reconstruction and induced nerve degeneration. They joined the cavernous plexus and were distributed forward with autonomic nerves to the adventitia of the internal carotid artery, emerging from the s...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Ruskell GL,Simons T

    更新日期:1987-12-01 00:00:00

  • Effects of excess iodine in chick embryo thyroid follicles: initial inhibition and subsequent hypertrophy.

    abstract::The effects of excess iodine on the development of the thyroid gland of chick embryos was assessed following injections of potassium iodide prior to incubation. Iodide injection resulted in a significantly greater thyroid gland weight (goitre) on Day 18 of incubation and a delay in hatching. Histological studies of th...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Guo Z,Narbaitz R,Fryer JN

    更新日期:1991-06-01 00:00:00

  • No change in neuron numbers in the dentate nucleus of patients with schizophrenia estimated with a new stereological method--the smooth fractionator.

    abstract::The dentate nucleus is phylogenetically the most recent nucleus in the cerebellum. Owing to its connections to the thalamus and the prefrontal cortex it may be involved in the symptomathology in schizophrenia and other psychiatric illnesses. In this stereological study we implemented the smooth fractionator, which com...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/j.0021-8782.2004.00337.x

    authors: Andersen BB,Fabricius K,Gundersen HJ,Jelsing J,Stark AK

    更新日期:2004-10-01 00:00:00

  • Observations on the development of the aortico-pulmonary spiral septum in the mouse.

    abstract::The differentiation of the bulbar region and arterial outflow tract of the developing mouse heart was investigated by analysing serial transverse sections through the heart region of mouse embryos isolated between the eleventh and fifteenth day of gestation. Over this period of time, we observed the configurational an...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Fananapazir K,Kaufman MH

    更新日期:1988-06-01 00:00:00

  • Mesencephalic human neural progenitor cells transplanted into the neonatal hemiparkinsonian rat striatum differentiate into neurons and improve motor behaviour.

    abstract::Neural stem cell transplantation is a promising strategy for the treatment of neurodegenerative diseases. To evaluate the differentiation potential of human neural progenitor cells (hNPCs) as a prerequisite for clinical trials, we intracerebrally transplanted in vitro expanded fetal mesencephalic hNPCs into hemiparkin...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/j.1469-7580.2006.00654.x

    authors: Hovakimyan M,Haas SJ,Schmitt O,Gerber B,Wree A,Andressen C

    更新日期:2006-12-01 00:00:00

  • The highly specialized vocal tract of the male Mongolian gazelle (Procapra gutturosa Pallas, 1777--Mammalia, Bovidae).

    abstract::The entire head and neck of a wild adult male Mongolian gazelle (Procapra gutturosa) was dissected with special reference to its enlarged larynx. Two additional adult male specimens taken from the wild were analysed by computer tomography. The sternomandibularis, omohyoideus, thyrohyoideus and hyoepiglotticus muscles ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.2003.00232.x

    authors: Frey R,Gebler A

    更新日期:2003-11-01 00:00:00

  • Vimentin, cytokeratin 8 and cytokeratin 18 are not specific markers for M-cells in human palatine tonsils.

    abstract::Standard immunohistochemical methods were used to detect the presence of vimentin, cytokeratin 8, cytokeratin 18, macrophages and Langerhans cells in the human tonsillar epithelium in formalin-fixed and frozen tissue specimens. Vimentin detection was restricted to infiltrating cells of the lymphoid series, dendritic a...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.2001.19960663.x

    authors: Koshi R,Mustafa Y,Perry ME

    更新日期:2001-12-01 00:00:00

  • Structure and mineralisation density of antler and pedicle bone in red deer (Cervus elaphus L.) exposed to different levels of environmental fluoride: a quantitative backscattered electron imaging study.

    abstract::The structure and relative degree of mineralisation of antler and pedicle bone of yearling red deer stags exposed either to low or high levels of environmental fluoride were determined by digital quantitative backscattered electron (BSE) imaging. Bone fluoride content (BFC) in antlers (845 +/- 86 mg F-/kg ash, arithme...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.2000.19610071.x

    authors: Kierdorf U,Kierdorf H,Boyde A

    更新日期:2000-01-01 00:00:00

  • Reconstructing phylogenies and phenotypes: a molecular view of human evolution.

    abstract::This review broadly summarizes how molecular biology has contributed to our understanding of human evolution. Molecular anthropology began in the 1960s with immunological comparisons indicating that African apes and humans were closely related and, indeed, shared a common ancestor as recently as 5 million years ago. A...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1469-7580.2007.00840.x

    authors: Bradley BJ

    更新日期:2008-04-01 00:00:00

  • Assessing the effectiveness of 30% sodium chloride aqueous solution for the preservation of fixed anatomical specimens: a 5-year follow-up study.

    abstract::Anatomical specimens used in human or veterinary anatomy laboratories are usually prepared with formaldehyde (a cancerous and teratogenic substance), glycerin (an expensive and viscous fluid), or ethanol (which is flammable). This research aimed to verify the viability of an aqueous 30% sodium chloride solution for pr...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/joa.12185

    authors: de Oliveira FS

    更新日期:2014-07-01 00:00:00

  • A collagen and elastic network in the wing of the bat.

    abstract::Bundles of collagen fibrils, elastic fibres and fibroblasts are organized into a network that lies in the plane of a large portion of the bat wing. By ultrastructural (TEM and SEM) and biochemical analyses it was found that individual bundles of the net are similar to elastic ligaments. Although elastic fibres predomi...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Holbrook KA,Odland GF

    更新日期:1978-05-01 00:00:00

  • Ultrastructural study of the relationship between the morphogenesis of filiform papillae and the keratinisation of the lingual epithelium in the rat.

    abstract::Tongues were removed from rat fetuses on d 16 of gestation (E16) and from newborn (P0) and juvenile rats on d 7 (P7) and d 21 (P21) postnatally for examination by light and transmission electron microscopy. In the fetuses at E16, no rudiments of filiform papillae were visible on the dorsal surface of the tongue. No ev...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.1999.19510027.x

    authors: Iwasaki S,Yoshizawa H,Kawahara I

    更新日期:1999-07-01 00:00:00

  • Macrophages and other endocytic cells in the mouse uterus during the second half of pregnancy and into the postpartum period.

    abstract::The spatiotemporal distribution of macrophages in the uterine wall of mice in the second half of pregnancy and the early postpartum period has been studied. Macrophages were identified using a combination of morphological criteria, the capacity to endocytose horseradish peroxidase and the expression of the Mac-1 antig...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Stewart IJ,Mitchell BS

    更新日期:1992-08-01 00:00:00

  • The permeability of the epithelium of the skin of fetal rats demonstrated with a lanthanum-containing solution.

    abstract::The permeability of the skin of fetal rats between 14 and 21 days of intrauterine life was investigated by injecting lanthanum nitrate solution subepidermally and by exposing the external surface of other fetuses to the same solution. Up to the age of 18 days, the epidermis was freely permeable from the basal surface ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Hayward AF

    更新日期:1983-03-01 00:00:00

  • Ultrastructure of the mouse spinal cord ependyma.

    abstract::This study was done in order to investigate the normal ultrastructure of well-preserved mouse spinal canal ependyma using light, scanning and transmission electron microscopy. The ependymal lining was found to consist of a simple, cuboidal epithelium essentially similar to the unspecialized cuboidal ependyma of the br...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Bjugn R,Haugland HK,Flood PR

    更新日期:1988-10-01 00:00:00

  • A new scenario for the evolutionary origin of hair, feather, and avian scales.

    abstract::In zoology it is well known that birds are characterized by the presence of feathers, and mammals by hairs. Another common point of view is that avian scales are directly related to reptilian scales. As a skin embryologist, I have been fascinated by the problem of regionalization of skin appendages in amniotes through...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1469-7580.2008.01041.x

    authors: Dhouailly D

    更新日期:2009-04-01 00:00:00

  • Anatomical Society Symposium on extramedullary haematopoiesis.

    abstract::A symposium on extramedullary haematopoiesis was held on 11-12 September 1996 at the University of St Andrews. The following are abstracts of papers and posters presented at the meeting. ...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1046/j.1469-7580.1997.19020311.x

    authors:

    更新日期:1997-02-01 00:00:00

  • Sustained swimming increases the mineral content and osteocyte density of salmon vertebral bone.

    abstract::This study addresses the effects of increased mechanical load on the vertebral bone of post-smolt Atlantic salmon by forcing them to swim at controlled speeds. The fish swam continuously in four circular tanks for 9 weeks, two groups at 0.47 body lengths (bl) × s(-1) (non-exercised group) and two groups at 2 bl × s(-1...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:10.1111/j.1469-7580.2011.01399.x

    authors: Totland GK,Fjelldal PG,Kryvi H,Løkka G,Wargelius A,Sagstad A,Hansen T,Grotmol S

    更新日期:2011-10-01 00:00:00

  • Ultrastructure of the zinc iodide-osmic acid stained cells in guinea pig small intestine.

    abstract::This study has demonstrated that cells stained using the zinc iodide-osmic acid (ZIO) method have the same fine structural features as those of fibroblasts. They have a well developed Golgi apparatus, granular endoplasmic reticulum and many mitochondria. They have no basal lamina. They are distributed in association w...

    journal_title:Journal of anatomy

    pub_type: 杂志文章

    doi:

    authors: Zhou DS,Komuro T

    更新日期:1995-10-01 00:00:00

  • Flow of information for emotions through temporal and orbitofrontal pathways.

    abstract::The posterior orbitofrontal cortex, anterior temporal sensory association areas and the amygdala have a key role in emotional processing and are robustly interconnected. By analogy with the pattern of connections in early processing sensory areas, anterior temporal sensory and polymodal association cortices send prima...

    journal_title:Journal of anatomy

    pub_type: 杂志文章,评审

    doi:10.1111/j.1469-7580.2007.00777.x

    authors: Barbas H

    更新日期:2007-08-01 00:00:00