Abstract：
:The dentate nucleus is phylogenetically the most recent nucleus in the cerebellum. Owing to its connections to the thalamus and the prefrontal cortex it may be involved in the symptomathology in schizophrenia and other psychiatric illnesses. In this stereological study we implemented the smooth fractionator, which combines the unbiased principles of the optical fractionator with a new and more efficient sampling strategy to the dentate nucleus. The smooth fractionator represents the most efficient sampling strategy described so far in stereology, in terms of reducing the sampling variance and thus increasing the efficiency. It is the first application of the smooth fractionator to human brain tissue and presents estimations of total number of neurons in the dentate nuclei of eight patients with schizophrenia compared to eight control persons. The total number of neurons in the dentate nucleus was estimated to 3.36 x 10(6) in subjects with schizophrenia, which was not statistically significant different from 3.65 x 10(6) in control subjects (P = 0.63). The advantages and disadvantages of the smooth fractionator method are discussed and its precision in practical application is estimated.
journal_name
J Anatjournal_title
Journal of anatomyauthors
Andersen BB,Fabricius K,Gundersen HJ,Jelsing J,Stark AKdoi
10.1111/j.0021-8782.2004.00337.xkeywords:
subject
Has Abstractpub_date
2004-10-01 00:00:00pages
313-21issue
4eissn
0021-8782issn
1469-7580pii
JOA337journal_volume
205pub_type
杂志文章abstract：:The ultrastructure of the basal lamina of histologically normal human breast tissue was determined in 19 women undergoing operations for removal of a fibroadenoma or reduction mammoplasty. The day of the menstrual cycle was determined by hormone assay and direct questioning. Previously documented ultrastructural appea...
journal_title：Journal of anatomy
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doi：
更新日期：1988-02-01 00:00:00
abstract：:Mastoid canals (tunnels) were observed in 41 (7.7%) of 265 dry human skulls. The canals were 2-27 mm long. This feature has not been reported before. dissection of 30 mastoid regions in cadavers showed that the canals contained a branch of the occipital artery and a vein. It is possible that during development of the ...
journal_title：Journal of anatomy
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abstract：:The behavioral differences in muscle use are related to the fiber type composition of the muscles among other variables. The aim of this study was to examine the degree of heterogeneity in the fiber type composition in the rat temporalis muscle. The temporalis muscle was taken from 10-week-old Wistar strain male rats ...
journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/j.1469-7580.2008.00990.x
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journal_title：Journal of anatomy
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doi：10.1046/j.1469-7580.1999.19420183.x
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journal_title：Journal of anatomy
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doi：
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abstract：:The occipital squama of the Japanese musk shrew, Suncus murinus, consists only of membrane bone which arises from the periosteal bony band of the supraoccipital cartilage. No cartilaginous tectum posterius, generally forming the dorsal border to the foramen magnum, was found in the developing chondrocranium. Also addi...
journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
pub_type： 杂志文章,多中心研究
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更新日期：2010-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1046/j.1469-7580.2001.19840481.x
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1996-02-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1980-05-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：
更新日期：1993-04-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
doi：10.1111/joa.12278
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journal_title：Journal of anatomy
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更新日期：1993-06-01 00:00:00
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journal_title：Journal of anatomy
pub_type： 杂志文章
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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doi：
更新日期：1996-04-01 00:00:00
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journal_title：Journal of anatomy
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journal_title：Journal of anatomy
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pub_type： 杂志文章
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journal_title：Journal of anatomy
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