Abstract:
:In a study of human diversity at a highly variable locus, we have mapped the internal structures of tandem-repetitive alleles from different populations at the minisatellite MS205 (D16S309). The results give an unusually detailed view of the different allelic structures represented on modern human chromosomes, and of the ancestral relationships between them. There was a clear difference in allelic diversity between African and non-African populations. A restricted set of allele families was found in non-African populations, and formed a subset of the much greater diversity seen on African chromosomes. The data strongly support a recent African origin for modern human diversity at this locus.
journal_name
Nat Genetjournal_title
Nature geneticsauthors
Armour JA,Anttinen T,May CA,Vega EE,Sajantila A,Kidd JR,Kidd KK,Bertranpetit J,Pääbo S,Jeffreys AJdoi
10.1038/ng0696-154subject
Has Abstractpub_date
1996-06-01 00:00:00pages
154-60issue
2eissn
1061-4036issn
1546-1718journal_volume
13pub_type
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