Effect of temperature on electrochemical deposition of calcium phosphate coatings in a simulated body fluid.


:Calcium phosphate coatings were deposited on titanium plate by an electrochemical method in simulated body fluid at 5-62 degrees C. X-ray diffractometry and FTIR studies demonstrated that the deposits at 5, 22 and 37 degrees C were amorphous and those at 52 and 62 degrees C contained Mg(OH)2, CaCO3 and carbonate apatite of low crystallinity. The calcium, magnesium and phosphorus contents of deposit increased in direct proportion to the square root of loading time of cathodic potential. Induction periods, which might be thought to be the time required to decrease the pH of the electrolyte around the cathode by the formation of H2 gas and to start deposition of calcium phosphate, were observed on all the regression lines. It is concluded that in the electrochemical synthesis of calcium phosphate in this temperature range the diffusion process is a rate-determining step.






Ban S,Maruno S




Has Abstract


1995-09-01 00:00:00














  • A nanoscale drug-entrapment strategy for hydrogel-based systems for the delivery of poorly soluble drugs.

    abstract::The hydrophilic nature of hydrogel matrices makes them disadvantageous to entrap poorly soluble therapeutic agents and greatly restricts their applications as drug-delivery systems. In this study, we demonstrated that sustained delivery of lipophilic drugs in hydrogel-based devices can be readily achieved by enhancing...


    pub_type: 杂志文章


    authors: Chen MC,Tsai HW,Liu CT,Peng SF,Lai WY,Chen SJ,Chang Y,Sung HW

    更新日期:2009-04-01 00:00:00

  • The effects of a functionally-graded scaffold and bone marrow-derived mononuclear cells on steroid-induced femoral head osteonecrosis.

    abstract::Osteonecrosis of the femoral head (ONFH) is a debilitating disease that may progress to femoral head collapse and subsequently, degenerative arthritis. Although injection of bone marrow-derived mononuclear cells (BMMCs) is often performed with core decompression (CD) in the early stage of ONFH, these treatments are no...


    pub_type: 杂志文章


    authors: Maruyama M,Nabeshima A,Pan CC,Behn AW,Thio T,Lin T,Pajarinen J,Kawai T,Takagi M,Goodman SB,Yang YP

    更新日期:2018-12-01 00:00:00

  • Phenformin-loaded polymeric micelles for targeting both cancer cells and cancer stem cells in vitro and in vivo.

    abstract::Conventional cancer chemotherapy often fails as most anti-cancer drugs are not effective against drug-resistant cancer stem cells. These surviving cancer stem cells lead to relapse and metastasis. In this study, an anti-diabetic drug, phenformin, capable of eliminating cancer stem cells was loaded into micelles via se...


    pub_type: 杂志文章


    authors: Krishnamurthy S,Ng VW,Gao S,Tan MH,Yang YY

    更新日期:2014-11-01 00:00:00

  • A graphene-based platform for induced pluripotent stem cells culture and differentiation.

    abstract::Induced pluripotent stem cells (iPSCs) hold great promise as a cell source for regenerative medicine yet its culture, maintenance of pluripotency and induction of differentiation remain challenging. Conversely, graphene (G) and graphene oxide (GO) have captured tremendous interests in the fields of materials science, ...


    pub_type: 杂志文章


    authors: Chen GY,Pang DW,Hwang SM,Tuan HY,Hu YC

    更新日期:2012-01-01 00:00:00

  • Metabolic disposition and elimination studies of a radiolabelled biodegradable polymeric implant in the rat brain.

    abstract::The metabolic disposition and elimination process of the anhydride co-polymer poly[1,3-bis(p-carboxy-phenoxypropane):sebacic acid] 20:80 [P(CPP:Sa)20:80] implanted in the rat brain was studied. Two polymers were prepared, one with [14C]SA and unlabelled CPP, and the other co-polymer with [14C]CPP and unlabelled SA. Wi...


    pub_type: 杂志文章


    authors: Domb AJ,Rock M,Schwartz J,Perkin C,Yipchuk G,Broxup B,Villemure JG

    更新日期:1994-07-01 00:00:00

  • An elastomeric material for facial prostheses: synthesis, experimental and numerical testing aspects.

    abstract::Current materials used for maxillofacial prostheses are far from ideal and there is a need for new improved materials which better simulate the tissues they are replacing. This study was based on a mixed experimental/analytical/numerical approach. A new polymeric material was developed to provide a better alternative ...


    pub_type: 杂志文章


    authors: Bellamy K,Limbert G,Waters MG,Middleton J

    更新日期:2003-12-01 00:00:00

  • Improvement of islet engrafts by enhanced angiogenesis and microparticle-mediated oxygenation.

    abstract::A major hindrance in islet transplantation as a feasible therapeutic approach for patients with type 1 diabetes is the insufficient oxygenation of the grafts, which results in cell death in portions of the implant. Here we address this limitation through the application of oxygen-generating microparticles (MP) and a f...


    pub_type: 杂志文章


    authors: Montazeri L,Hojjati-Emami S,Bonakdar S,Tahamtani Y,Hajizadeh-Saffar E,Noori-Keshtkar M,Najar-Asl M,Ashtiani MK,Baharvand H

    更新日期:2016-05-01 00:00:00

  • Quasi-living surface graft polymerization with phosphorylcholine group(s) at the terminal end.

    abstract::A surface graft polymer with one or two phosphorylcholine (PC) polarheads at the terminus of the growing chain end was prepared by sequential reactions on a glass substrate. The dithiocarbamate group covalently bound to glass surfaces was derivatized with one or two PC groups and then irradiated with ultraviolet light...


    pub_type: 杂志文章


    authors: Matsuda T,Kaneko M,Ge S

    更新日期:2003-11-01 00:00:00

  • In vitro evaluations of innate and acquired immune responses to electrospun polydioxanone-elastin blends.

    abstract::Immune response testing of biomaterials is an essential component of biocompatibility assessment, particularly when the materials of interest are used to design bioresorbable scaffolds with the potential to promote in situ regeneration. Current trends in immune response testing of biomaterials typically examine few el...


    pub_type: 杂志文章


    authors: Smith MJ,White KL Jr,Smith DC,Bowlin GL

    更新日期:2009-01-01 00:00:00

  • Porous titanium scaffolds fabricated using a rapid prototyping and powder metallurgy technique.

    abstract::One of the main issues in orthopaedic implant design is the fabrication of scaffolds that closely mimic the biomechanical properties of the surrounding bone. This research reports on a multi-stage rapid prototyping technique that was successfully developed to produce porous titanium scaffolds with fully interconnected...


    pub_type: 杂志文章


    authors: Ryan GE,Pandit AS,Apatsidis DP

    更新日期:2008-09-01 00:00:00

  • Bulk, surface and blood-contacting properties of polyether polyurethanes modified with polydimethylsiloxane macroglycols.

    abstract::The bulk, surface and blood-contacting properties of a series of polyether polyurethanes, modified with three different polydimethylsiloxane (PDMS) macroglycol segments, were evaluated. The PDMS oligomers were terminated with hydroxy-tipped end groups of varying polarity. The effect of substituting the polytetramethyl...


    pub_type: 杂志文章


    authors: Okkema AZ,Fabrizius DJ,Grasel TG,Cooper SL,Zdrahala RJ

    更新日期:1989-01-01 00:00:00

  • Electrospinning of collagen nanofibers: effects on the behavior of normal human keratinocytes and early-stage wound healing.

    abstract::Electrospinning of type I collagen in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) to fabricate a biomimetic nanofibrous extracellular matrix for tissue engineering was investigated. The average diameter of collagen nanofibers electrospun from 8% collagen solution in HFIP was 460 nm (range of 100-1200 nm). The as-spun col...


    pub_type: 杂志文章


    authors: Rho KS,Jeong L,Lee G,Seo BM,Park YJ,Hong SD,Roh S,Cho JJ,Park WH,Min BM

    更新日期:2006-03-01 00:00:00

  • A combined hiPSC-derived endothelial cell and in vitro microfluidic platform for assessing biomaterial-based angiogenesis.

    abstract::Human induced pluripotent stem cell (hiPSC) derived angiogenesis models present a unique opportunity for patient-specific platforms to study the complex process of angiogenesis and the endothelial cell response to biomaterial and biophysical changes in a defined microenvironment. We present a refined method for differ...


    pub_type: 杂志文章


    authors: Natividad-Diaz SL,Browne S,Jha AK,Ma Z,Hossainy S,Kurokawa YK,George SC,Healy KE

    更新日期:2019-02-01 00:00:00

  • PEGylated TNF-related apoptosis-inducing ligand (TRAIL) for effective tumor combination therapy.

    abstract::Although PEGylated TNF-related apoptosis-inducing ligand (PEG-TRAIL) has good tumor cell specificity and stability, its therapeutic potential is restricted by the development of tumor cell resistance. The purpose of this study was to develop an effective combination therapy with sustained biological activity based on ...


    pub_type: 杂志文章


    authors: Jiang HH,Kim TH,Lee S,Chen X,Youn YS,Lee KC

    更新日期:2011-11-01 00:00:00

  • Drug delivery from gold and titanium surfaces using self-assembled monolayers.

    abstract::Currently available drug-eluting stents (DES) use polymers for coating and releasing drugs. Increasing evidence suggests that inflammatory and hypersensitive reactions are caused by such polymer coatings. This study focused on developing new techniques for delivering drugs directly from metal implant surfaces. Hydroxy...


    pub_type: 杂志文章


    authors: Mani G,Johnson DM,Marton D,Feldman MD,Patel D,Ayon AA,Agrawal CM

    更新日期:2008-12-01 00:00:00

  • Chloride- and alkali-containing calcium phosphates as basic materials to prepare calcium phosphate cements.

    abstract::Combinations of an alkali-containing calcium phosphate-like rhenanite, sodium whitlockite or calcium potassium phosphate and a chloride-containing calcium phosphate-like spodiosite or chloroapatite with or without additions of other calcium phosphates like monocalcium phosphate monohydrate, dicalcium phosphate or dica...


    pub_type: 杂志文章


    authors: Bermúdez O,Boltong MG,Driessens FC,Ginebra MP,Fernández E,Planell JA

    更新日期:1994-10-01 00:00:00

  • Transduced PEP-1-PON1 proteins regulate microglial activation and dopaminergic neuronal death in a Parkinson's disease model.

    abstract::Parkinson's disease (PD) is an oxidative stress-mediated neurodegenerative disorder caused by selective dopaminergic neuronal death in the midbrain substantia nigra. Paraoxonase 1 (PON1) is a potent inhibitor of low-density lipoprotein (LDL) and high-density lipoprotein (HDL) against oxidation by destroying biological...


    pub_type: 杂志文章


    authors: Kim MJ,Park M,Kim DW,Shin MJ,Son O,Jo HS,Yeo HJ,Cho SB,Park JH,Lee CH,Kim DS,Kwon OS,Kim J,Han KH,Park J,Eum WS,Choi SY

    更新日期:2015-09-01 00:00:00

  • The effect of long-term release of Shh from implanted biodegradable microspheres on recovery from spinal cord injury in mice.

    abstract::After spinal cord injury (SCI), loss of cells and damage to ascending and descending tracts can result in paralysis. Current treatments for SCI are based on patient stabilization, and much-needed regenerative therapies are still under development. To activate and instruct stem and progenitor cells or injured tissue to...


    pub_type: 杂志文章


    authors: Lowry N,Goderie SK,Lederman P,Charniga C,Gooch MR,Gracey KD,Banerjee A,Punyani S,Silver J,Kane RS,Stern JH,Temple S

    更新日期:2012-04-01 00:00:00

  • Programmed degradation of a hierarchical nanoparticle with redox and light responsivity for self-activated photo-chemical enhanced chemodynamic therapy.

    abstract::Chemodynamic therapy (CDT) has recently emerged as a promising treatment for cancer due to the high specificity of CDT towards tumor microenvironment (TME). However, the low efficiency of reactive oxygen species (ROS) generation and the robust ROS defensive mechanisms in cancer cells remain critical hurdles for curren...


    pub_type: 杂志文章


    authors: Wang S,Yang L,Cho HY,Dean Chueng ST,Zhang H,Zhang Q,Lee KB

    更新日期:2019-12-01 00:00:00

  • Biomaterial-induced alterations of human neutrophils under fluid shear stress: scanning electron microscopical study in vitro.

    abstract::Morphological changes of human polymorphonuclear neutrophils (PMN) adhering to hydrophilic (glass) and hydrophobic (FEP-Teflon, polyethylene, polypropylene) surfaces were studied in a parallel-plate flow chamber at the light and scanning electron microscopical levels. The PMN were exposed to a shear stress of 0.19 Pa ...


    pub_type: 杂志文章


    authors: Tomczok J,Sliwa-Tomczok W,Klein CL,van Kooten TG,Kirkpatrick CJ

    更新日期:1996-07-01 00:00:00

  • Development of a soft tissue seal around bone-anchored transcutaneous amputation prostheses.

    abstract::Conventional amputation prosthetics are problematic because they rely on the stump-socket interface for attachment. Intraosseous transcutaneous amputation prostheses (ITAP) could solve these problems; however they rely on the integrity of the soft tissue-implant interface as a barrier to exogenous agents, and in the p...


    pub_type: 杂志文章


    authors: Pendegrass CJ,Goodship AE,Blunn GW

    更新日期:2006-08-01 00:00:00

  • The immobilization of proteins on biodegradable polymer fibers via click chemistry.

    abstract::A facile and efficient method to immobilize bioactive proteins onto polymeric substrate was established. Testis-specific protease 50 (TSP50) was immobilized on ultrafine biodegradable polymer fibers, i.e., (1) to prepare a propargyl-containing polymer P(LA90-co-MPC10) by introducing propargyl group into a cyclic carbo...


    pub_type: 杂志文章


    authors: Shi Q,Chen X,Lu T,Jing X

    更新日期:2008-03-01 00:00:00

  • Multifunctional silica nanotubes for dual-modality gene delivery and MR imaging.

    abstract::This work demonstrated the development of multifunctional silica nanotubes (SNT) by functionalization of their inner void and outer surface with magnetic-fluorescence nanocomposites and cationic polymers, respectively. The successful construction of BPEI-SNT was established by electron energy loss spectroscopy in conj...


    pub_type: 杂志文章


    authors: Namgung R,Zhang Y,Fang QL,Singha K,Lee HJ,Kwon IK,Jeong YY,Park IK,Son SJ,Kim WJ

    更新日期:2011-04-01 00:00:00

  • Mechanism of initial attachment of cells derived from human bone to commonly used prosthetic materials during cell culture.

    abstract::The suitability of polymeric biomaterials as surfaces for the attachment and growth of cells has often been investigated in cell culture. In this study the contribution that serum fibronectin (Fn) or vitronectin (Vn) make to the attachment and spreading of cells cultured from explanted human bone (bone-derived cells) ...


    pub_type: 杂志文章


    authors: Howlett CR,Evans MD,Walsh WR,Johnson G,Steele JG

    更新日期:1994-02-01 00:00:00

  • Interactions between endothelial cells and a poly(carbonate-silsesquioxane-bridge-urea)urethane.

    abstract::We have recently developed a polymer which contains silsesquioxane in the form of nano-bridges poly(carbonate-silsesquioxane-bridge-urea)urethane (PCBSU) for cardiovascular device applications. The polymer has been characterised and the durability has been confirmed with long-term in vivo tests. The aim of this study ...


    pub_type: 杂志文章


    authors: Punshon G,Vara DS,Sales KM,Kidane AG,Salacinski HJ,Seifalian AM

    更新日期:2005-11-01 00:00:00

  • The use of RANKL-coated brushite cement to stimulate bone remodelling.

    abstract::Calcium phosphate cements were first proposed as synthetic bone substitutes over two decades ago, however, they are characterised by slow chemical or cellular resorption and a slow osteointegration. In contrast, bone autograft has been shown to stimulate osteoclastogenesis and angiogenesis resulting in active bone rem...


    pub_type: 杂志文章


    authors: Le Nihouannen D,Hacking SA,Gbureck U,Komarova SV,Barralet JE

    更新日期:2008-08-01 00:00:00

  • Antibacterial activity of bactericide-immobilized filler for resin-based restoratives.

    abstract::This study examined the antibacterial activity of prepolymerized resin filler, in which the bactericide quaternary ammonium was immobilized. The experimental filler was prepared by grinding prepolymerized resin blocks of methacrylate monomers, silica particles, and the antibacterial monomer methacryloyloxydodecylpyrid...


    pub_type: 杂志文章


    authors: Imazato S,Ebi N,Takahashi Y,Kaneko T,Ebisu S,Russell RR

    更新日期:2003-09-01 00:00:00

  • Expression of the α5 integrin gene in corneal epithelial cells cultured on tissue-engineered human extracellular matrices.

    abstract::The integrin α5β1 plays a major role in corneal wound healing by promoting epithelial cell adhesion and migration over the fibronectin matrix secreted as a cellular response to corneal damage. Expression of α5 is induced when rabbit corneal epithelial cells (RCECs) are grown in the presence of fibronectin. Here, we ex...


    pub_type: 杂志文章


    authors: Lake J,Zaniolo K,Gaudreault M,Carrier P,Deschambault A,Bazin R,Germain L,Salesse C,Guérin SL

    更新日期:2013-09-01 00:00:00

  • The use of folate-PEG-grafted-hybranched-PEI nonviral vector for the inhibition of glioma growth in the rat.

    abstract::Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic efficacy in vivo when the cytosine deaminase/5-fluorocytosine (CD/5-FC) a...


    pub_type: 杂志文章


    authors: Liang B,He ML,Chan CY,Chen YC,Li XP,Li Y,Zheng D,Lin MC,Kung HF,Shuai XT,Peng Y

    更新日期:2009-08-01 00:00:00

  • In vivo cytokine-associated responses to biomaterials.

    abstract::Cytokines, chemokines, and growth factors were analyzed periodically over eight weeks from the wound exudate fluid surrounding biomaterials implanted subcutaneously within stainless steel mesh cages. TNF-alpha, MCP-1, MIP-1alpha, IL-2, IL-6, IL-1beta, VEGF, IL-4, and IL-10 were measured from exudate samples collected ...


    pub_type: 杂志文章


    authors: Schutte RJ,Xie L,Klitzman B,Reichert WM

    更新日期:2009-01-01 00:00:00