Auditory pathway plasticity in adult humans after unilateral idiopathic sudden sensorineural hearing loss.

Abstract:

:We recorded auditory evoked magnetic fields from 8 patients with unilateral, idiopathic, sudden, sensorineural hearing loss and from 8 healthy controls, using a 122-channel whole-scalp neuromagnetometer. The stimuli were 50-ms l-kHz tone bursts, delivered to the healthy ear at interstimulus intervals (ISIs) of 1, 2, 4, 8, and 16 s. On average, as in normal-hearing controls, the dipole moments and the latencies of N100m, the 100-ms response, increased as a function of ISI over both hemispheres to left- and right-ear stimulation. Four patients had shorter response latencies and 4 had stronger dipole moments over the hemisphere ipsilateral to the stimulation. In 3 patients, one additional source was observed over the anterolateral right hemisphere and another near head midline. These findings suggest that unilateral sensorineural hearing loss may modify information processing in the central auditory pathways.

journal_name

Hear Res

journal_title

Hearing research

authors

Vasama JP,Mäkelä JP

doi

10.1016/0378-5955(95)00086-j

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

132-40

issue

1-2

eissn

0378-5955

issn

1878-5891

pii

0378-5955(95)00086-J

journal_volume

87

pub_type

杂志文章
  • In vitro differentiation of mouse embryo statoacoustic ganglion and sensory epithelium.

    abstract::Interactions between the statoacoustic ganglion and sensory vestibular epithelia have been investigated using different methods of organ and tissue cultures taken from mouse embryos on gestation day 13. Ultrastructural and biochemical observations of the degree of maturation of vestibular sensory cells and ganglion ne...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(87)90152-3

    authors: Raymond J

    更新日期:1987-01-01 00:00:00

  • Coincidence detection in auditory neurons: a possible mechanism to enhance stimulus specificity in the grassfrog.

    abstract::It is still a matter of debate whether neurons in the higher central nervous system of anurans become progressively more sharply tuned to sounds that have a behavioral importance or that such coding is performed by (small) groups of neurons. The approach we have taken to investigate this matter comprises simultaneous ...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(87)90138-9

    authors: Eggermont JJ,Epping WJ

    更新日期:1987-01-01 00:00:00

  • Eardrum and columella displacement in single ossicle ears under quasi-static pressure variations.

    abstract::Although most birds encounter large pressure variations during flight, motion of the middle ear components as a result of changing ambient pressure are not well known or described. In the present study, motion of the columella footplate and tympanic membrane (extrastapedius) in domestic chickens (Gallus gallus domesti...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2018.05.012

    authors: Claes R,Muyshondt PGG,Van Assche F,Van Hoorebeke L,Aerts P,Dirckx JJJ

    更新日期:2018-08-01 00:00:00

  • The columnar and layer-specific response properties of neurons in the primary auditory cortex of Mongolian gerbils.

    abstract::The columnar and layer-specific response properties of neurons in the primary auditory cortex (AI) of Mongolian gerbils were studied using single-unit recordings of responses to tone-burst stimuli presented to the ear contralateral to the recording side. During near-radial microelectrode penetrations of the AI in 100-...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(97)00119-6

    authors: Sugimoto S,Sakurada M,Horikawa J,Taniguchi I

    更新日期:1997-10-01 00:00:00

  • The time course of recovery from suppression and facilitation from single units in the mammalian cochlear nucleus.

    abstract::The responses to two identical, consecutive pure tone stimuli with varying inter-stimulus intervals (delta ts) were measured for 89 neurons in the cochlear nucleus of the anaesthetised guinea pig. We observed two main effects; either a decrease (suppression) or an increase (facilitation) in response to the second tone...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2005.12.005

    authors: Bleeck S,Sayles M,Ingham NJ,Winter IM

    更新日期:2006-02-01 00:00:00

  • Influence of contralateral acoustic stimulation on distortion-product and spontaneous otoacoustic emissions in the barn owl.

    abstract::The avian auditory papilla provides an interesting object on which to study efferent influences, because whereas a significant population of hair cells in birds is not afferently innervated, all hair cells are efferently innervated (Fischer, 1992, 1994a, b). Previous studies in mammals using contralateral sound to sti...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(99)00126-4

    authors: Manley GA,Taschenberger G,Oeckinghaus H

    更新日期:1999-12-01 00:00:00

  • Localization of the mitochondrial uncoupling protein family in the rat inner ear.

    abstract::Uncoupling proteins (UCPs) are a proton transporter family located in the mitochondrial inner membrane. The molecular expression and activity of UCPs in brown adipose tissue and skeletal muscle are regulated by factors as diverse as chronic overeating and cold exposure, suggesting roles in energy expenditure and heat ...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2004.02.002

    authors: Kitahara T,Li HS,Balaban CD

    更新日期:2004-10-01 00:00:00

  • Contributions of von Békésy to psychoacoustics.

    abstract::This paper reviews the contributions of von Békésy to psychoacoustics, comparing his findings and interpretations to those that have emerged since his work. The areas covered include the perception of pitch for pure tones and complex tones, the effect of frequency on the apparent location of pure tones, estimation of ...

    journal_title:Hearing research

    pub_type: 历史文章,杂志文章,评审

    doi:10.1016/j.heares.2012.04.009

    authors: Moore BC

    更新日期:2012-11-01 00:00:00

  • The effect of BAPTA and 4AP in scala media on transduction and cochlear gain.

    abstract::We have injected by iontophoresis 4-amino-pyridine, a K+ channel blocker and BAPTA, (a Ca++ chelator), into scala media of the first three turns of the guinea pig cochlea. We measured the reduction in outer hair cell (OHC) receptor current, as indicated by cochlear microphonic measured in scala media evoked by a 207 H...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2005.05.016

    authors: Sellick PM,Robertson D,Patuzzi R

    更新日期:2006-01-01 00:00:00

  • GJB2 gene mutations in newborns with non-syndromic hearing impairment in Northern China.

    abstract::Mutations in GJB2 account for the majority of recessive forms of prelingual hearing loss. However, in most previous studies it was not possible to distinguish between congenital (present at birth) and non-congenital prelingual hearing loss. In the present study, the frequency of GJB2 alleles in 20 newborns with bilate...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2004.06.012

    authors: Shi GZ,Gong LX,Xu XH,Nie WY,Lin Q,Qi YS

    更新日期:2004-11-01 00:00:00

  • Incorporation of D-[3H]-glucosamine and L-[3H]-fucose into the developing rat cochlea.

    abstract::The uptake of two tritiated carbohydrates, D-[3H]-glucosamine and L-[3H]-fucose, to the developing rat cochlea was examined using light and electron microscopic radioautography. Both carbohydrates, administered to in vitro developing rat cochleas, shared a similar ultrastructural labeling pattern on the microvilli and...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(91)90072-h

    authors: Gil-Loyzaga P,Gabrion J,Remezal M,Nguyen-Than-Dao B,Uziel A

    更新日期:1991-12-01 00:00:00

  • Focal electrical stimulation of dorsal nucleus of the lateral lemniscus modulates auditory response properties of inferior collicular neurons in the albino mouse.

    abstract::The inferior colliculus (IC) receives and integrates excitatory and inhibitory inputs from many bilateral lower auditory nuclei, intrinsic projections within IC, contralateral IC through the commissure of IC and from the auditory cortex (AC). These excitatory and inhibitory inputs from both ascending and descending au...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2019.01.024

    authors: Wang X,Cheng YL,Yang DD,Si WJ,Jen PH,Yang CH,Chen QC

    更新日期:2019-06-01 00:00:00

  • Auditory experience affects degeneration of the ventral cochlear nucleus in Mongolian gerbils.

    abstract::Gerbils exhibit a unique encephalopathy characterized by spongioform lesions in the neuropil of the cochlear nucleus and that others have recently described. The present results suggest that the course of this degenerative disorder is affected by acoustic experience. In gerbils in which acoustic stimulation was limite...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(87)90193-6

    authors: McGinn MD,Faddis BT

    更新日期:1987-12-31 00:00:00

  • Morphology of the endolymphatic sac in the guinea pig after an acute endolymphatic hydrops.

    abstract::The role of the endolymphatic sac (ES) in endolymph volume homeostasis is speculative. The present study investigates changes of the ES's epithelia and luminal filling after induction of an acute endolymphatic hydrops. After microinjection of 1.1 mul artificial endolymph into scala media of the cochlea, guinea pigs we...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2004.10.010

    authors: Valk WL,Wit HP,Segenhout JM,Dijk F,van der Want JJ,Albers FW

    更新日期:2005-04-01 00:00:00

  • Postnatal development of 2f1-f2 otoacoustic emissions in pigmented rat.

    abstract::Distortion-product emissions at 2f1-f2 were measured in developing, pigmented rats to determine the characteristics of the functional onset and maturation of these emitted responses. Distortion-product testing was conducted on postnatal days 12, 14, 18, 21, 24, 28, and 51. The geometric-mean frequencies of the primari...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(90)90223-c

    authors: Henley CM 3rd,Owings MH,Stagner BB,Martin GK,Lonsbury-Martin BL

    更新日期:1990-01-01 00:00:00

  • Rapid recovery of sensory function in blind cave fish treated with anemone repair proteins.

    abstract::Blind cave fish employ superficial neuromasts to detect currents [Baker, C.F. and J.C. Montgomery, J. Comp. Physiol. A 184 (1999) 519-527]. Briefly exposing fish to calcium-free water significantly reduces the ability of the fish to perform rheotaxis (i.e., to orient properly in currents). Spontaneous recovery to cont...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(02)00705-0

    authors: Berg A,Watson GM

    更新日期:2002-12-01 00:00:00

  • Distortion product otoacoustic emission suppression tuning curves in human adults and neonates.

    abstract::Distortion product otoacoustic emission (DPOAE) iso-suppression tuning curves (STC) were generated in 15 normal-hearing adults and 16 healthy term-born neonates for three f2 frequencies. The 2f1-f2 DPOAE was elicited using f2/f1 = 1.2, LI = 1.2, LI = 65 and L2 = 50 dB SPL. A suppressor tone was presented at frequencie...

    journal_title:Hearing research

    pub_type: 临床试验,杂志文章

    doi:10.1016/0378-5955(96)00056-1

    authors: Abdala C,Sininger YS,Ekelid M,Zeng FG

    更新日期:1996-09-01 00:00:00

  • Pre- and postsynaptic excitatory action of glutamate agonists on frog vestibular receptors.

    abstract::In order to investigate the localization and the type(s) of excitatory amino acid receptors in the frog vestibular system, the exogenous amino acid agonists Quisqualic acid, Kainic acid and N-methyl-D-aspartic acid were tested on the sensory organ of semicircular canals. Intracellular recordings of the resting dischar...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(90)90006-b

    authors: Prigioni I,Russo G,Valli P,Masetto S

    更新日期:1990-07-01 00:00:00

  • Structural relationships of the unfixed tectorial membrane.

    abstract::Although the tectorial membrane has a key role in the function of the organ of Corti, its structural relationship within the cochlear partition is still not fully characterised. Being an acellular structure, the tectorial membrane is not readily stained with dyes and is thus difficult to visualise. We present here det...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(00)00208-2

    authors: Ulfendahl M,Flock A,Scarfone E

    更新日期:2001-01-01 00:00:00

  • Computational models of hair cell bundle mechanics: III. 3-D utricular bundles.

    abstract::Six utricular hair bundles from a red-eared turtle are modeled using 3-D finite element analysis. The mechanical model includes shear deformable stereocilia, realignment of all forces during force load increments, and tip and lateral link inter-stereocilia connections. Results show that there are two distinct bundle t...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2004.06.006

    authors: Silber J,Cotton J,Nam JH,Peterson EH,Grant W

    更新日期:2004-11-01 00:00:00

  • Ethacrynic acid rapidly and selectively abolishes blood flow in vessels supplying the lateral wall of the cochlea.

    abstract::The mechanisms underlying the ototoxicity of ethacrynic acid (EA) are not fully understood. Previous studies have focused on morphologic and enzymatic changes in the stria vascularis. The current experiment shows that one of the earliest effects of EA is ischemia, resulting from impaired blood flow in vessels supplyin...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(02)00585-3

    authors: Ding D,McFadden SL,Woo JM,Salvi RJ

    更新日期:2002-11-01 00:00:00

  • Loss of inner hair cell ribbon synapses and auditory nerve fiber regression in Cldn14 knockout mice.

    abstract::Proper functioning of the auditory nerve is of critical importance for auditory rehabilitation by cochlear implants. Here we used the Cldn14-/- mouse to study in detail the effects of Claudin 14 loss on auditory synapses and the auditory nerve. Mutations in the tight junction protein Claudin 14 cause autosomal recessi...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2020.107950

    authors: Claußen M,Schulze J,Nothwang HG

    更新日期:2020-06-01 00:00:00

  • Nitrosoglutathione suppresses cochlear potentials and DPOAEs but not outer hair cell currents or voltage-dependent capacitance.

    abstract::Biochemical and pharmacological evidence support a role for nitric oxide (NO) and glutathione (GSH) in the cochlea. GSH combines with NO in tissue to form nitrosoglutathione (GSNO) that can act as a storage form for GSH and NO. Therefore, we tested GSNO on sound-evoked responses of the cochlea (cochlear microphonic, C...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(97)00065-8

    authors: Nenov AP,Skellett RA,Fallon M,Bobbin RP

    更新日期:1997-08-01 00:00:00

  • Effect of inter-phase gap on the sensitivity of cochlear implant users to electrical stimulation.

    abstract::Human behavioral thresholds for trains of biphasic pulses applied to a single channel of Nucleus CI24 and LAURA cochlear implants were measured as a function of inter-phase gap (IPG). Experiment 1 used bipolar stimulation, a 100-pps pulse rate, and a 400-ms stimulus duration. In one condition, the two phases of each p...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2005.03.021

    authors: Carlyon RP,van Wieringen A,Deeks JM,Long CJ,Lyzenga J,Wouters J

    更新日期:2005-07-01 00:00:00

  • Simultaneous rather than retrograde spiral ganglion cell degeneration following ototoxically induced hair cell loss in the guinea pig cochlea.

    abstract::Severe damage to the organ of Corti leads to degeneration of the spiral ganglion cells (SGCs) which form the auditory nerve. This degeneration starts at the level of synaptic connection of the peripheral processes (PPs) of SGCs with the cochlear hair cells. It is generally thought that from this point SGC degeneration...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2020.107928

    authors: Ramekers D,Klis SFL,Versnel H

    更新日期:2020-05-01 00:00:00

  • Cytoarchitecture of the human superior olivary complex: nuclei of the trapezoid body and posterior tier.

    abstract::The superior olivary complex (SOC) is a cluster of nuclei situated in the caudal brainstem tegmentum that forms an essential component of the auditory pathway. The SOC includes two principal nuclei, the medial and lateral superior olives (MSO and LSO respectively), that have clear roles in sound source localization. S...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2008.04.010

    authors: Kulesza RJ Jr

    更新日期:2008-07-01 00:00:00

  • Immunolabeling type II collagen in the basilar membrane, a pre-embedding approach.

    abstract::This paper describes the development of a protocol that can be used to detect collagen II in the healthy adult basilar membrane (BM) at the electron microscopic level. This protocol required aggressive epitope exposure techniques to break the crosslinks that bind the collagen molecules tightly into fibrils and to remo...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(02)00313-1

    authors: Dreiling FJ,Henson MM,Henson OW Jr

    更新日期:2002-04-01 00:00:00

  • Cochlear-implant spatial selectivity with monopolar, bipolar and tripolar stimulation.

    abstract::Sharp spatial selectivity is critical to auditory performance, particularly in pitch-related tasks. Most contemporary cochlear implants have employed monopolar stimulation that produces broad electric fields, which presumably contribute to poor pitch and pitch-related performance by implant users. Bipolar or tripolar ...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/j.heares.2011.11.005

    authors: Zhu Z,Tang Q,Zeng FG,Guan T,Ye D

    更新日期:2012-01-01 00:00:00

  • Calcification processes in the chick otoconia and calcium binding proteins: patterns of tetracycline incorporation and calbindin-D28K distribution.

    abstract::In order to clarify the otoconia formation and turnover, tetracycline, an antibiotic that precipitates at calcifying fronts and serves as a fluorescent marker, was injected into eggs at different stages of chick embryonic development, as well as into postnatal chicken and into adult animals. The changes in the intensi...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/s0378-5955(00)00094-0

    authors: Balsamo G,Avallone B,Del Genio F,Trapani S,Marmo F

    更新日期:2000-10-01 00:00:00

  • Summating potential (SP) tuning curves.

    abstract::Two methods were used to extract frequency specific information from the gross d.c. cochlear potential, the summating potential (SP). The first approach was to derive SP tuning curves using a two-tone simultaneous masking procedure; the second to obtain SP iso-response functions. The influence of various parameter cha...

    journal_title:Hearing research

    pub_type: 杂志文章

    doi:10.1016/0378-5955(84)90009-1

    authors: Cheatham MA,Dallos P

    更新日期:1984-11-01 00:00:00