Abstract：
:The superior olivary complex (SOC) is a cluster of nuclei situated in the caudal brainstem tegmentum that forms an essential component of the auditory pathway. The SOC includes two principal nuclei, the medial and lateral superior olives (MSO and LSO respectively), that have clear roles in sound source localization. Surrounding the principal nuclei are a number of periolivary nuclei (PON) that vary significantly between mammalian species but function in multiple aspects of hearing. Although the PON have been studied in numerous laboratory animals, these nuclei have not been delineated in human. The major goal of this study is to, based on myeloarchitecture, location, neuronal morphology and cytoarchitecture, define the PON within the human SOC and provide estimates of neuronal number within these nuclei. Results from the study of twelve human brainstems provide evidence for six morphologically distinct cell groups: three within the trapezoid body and three along the posterior aspect of the SOC. Based on the analysis of human tissue stained for myelin, Nissl substance, or impregnated with silver, the human PON appear largely homologous to the PON described in other low-frequency hearing animals.
journal_name
Hear Resjournal_title
Hearing researchauthors
Kulesza RJ Jrdoi
10.1016/j.heares.2008.04.010subject
Has Abstractpub_date
2008-07-01 00:00:00pages
52-63issue
1-2eissn
0378-5955issn
1878-5891pii
S0378-5955(08)00082-8journal_volume
241pub_type
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