Abstract:
:The role of basic fibroblast growth factor (bFGF) in the control of teratoma cell proliferation was examined. It was found that bFGF stimulates proliferation at low concentrations but induces cell migration at higher doses. These effects could be efficiently counteracted by addition of protamine sulphate. Moreover the bFGF gene is actively transcribed in primary human testicular embryonal carcinomas but was not expressed in any other embryonic tumour examined. The biological implications of these findings will be discussed.
journal_name
Eur Uroljournal_title
European urologyauthors
Granérus M,Welin A,Lundh B,Schofield PN,Ekström TJ,Engström Wdoi
10.1159/000474573subject
Has Abstractpub_date
1993-01-01 00:00:00pages
76-81issue
1eissn
0302-2838issn
1873-7560journal_volume
23pub_type
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