Heparin binding growth factors and the control of teratoma cell proliferation.

Abstract:

:The role of basic fibroblast growth factor (bFGF) in the control of teratoma cell proliferation was examined. It was found that bFGF stimulates proliferation at low concentrations but induces cell migration at higher doses. These effects could be efficiently counteracted by addition of protamine sulphate. Moreover the bFGF gene is actively transcribed in primary human testicular embryonal carcinomas but was not expressed in any other embryonic tumour examined. The biological implications of these findings will be discussed.

journal_name

Eur Urol

journal_title

European urology

authors

Granérus M,Welin A,Lundh B,Schofield PN,Ekström TJ,Engström W

doi

10.1159/000474573

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

76-81

issue

1

eissn

0302-2838

issn

1873-7560

journal_volume

23

pub_type

杂志文章
  • Methotrexate, vinblastine, adriamycin and cisplatin versus methotrexate and cisplatin in advanced urothelial cancer. A randomized study.

    abstract::From September 1984 to December 1988, 28 consecutive patients with metastatic urothelial cancer entered a randomized study to compare 4 courses of modified methotrexate, vinblastine, adriamycin and cisplatin (M-VAC) to 4 courses of methotrexate followed by folinic acid rescue and cisplatin (MP). Non-responders or rela...

    journal_title:European urology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1159/000471672

    authors: Pizzocaro G,Milani A,Piva L,Faustini M,Spino E

    更新日期:1991-01-01 00:00:00

  • Postpubertal cryptorchism. Morphofunctional study with special reference to Leydig's cells.

    abstract::In a group of 17 patients of postpubertal age with unilateral (n = 15) or bilateral (n = 2) cryptorchism, a significant decrease in the tubular diameter was observed, in addition to Leydig cell hyperplasia (many with cytoplasm vacuolization and/or atrophy) in both the cryptorchid testes and in the contralateral scrota...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471635

    authors: Sirvent JJ,Bernat R,Rodriguez Tolra J,Navarro MA,Garcia B,Brunet J

    更新日期:1989-01-01 00:00:00

  • Androgen-deprivation therapy and diabetes control among diabetic men with prostate cancer.

    abstract:BACKGROUND:Androgen-deprivation therapy (ADT) for prostate cancer (PCa) is associated with decreased insulin sensitivity and increased diabetes risk among nondiabetic men. Few data are available about the effects of ADT on diabetes control among men with diabetes. OBJECTIVE:We examined care for men who had diabetes at...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2013.02.023

    authors: Keating NL,Liu PH,O'Malley AJ,Freedland SJ,Smith MR

    更新日期:2014-04-01 00:00:00

  • Treatment of anterior vaginal wall prolapse with porcine skin collagen implant by the transobturator route: preliminary results.

    abstract:OBJECTIVE:To assess the feasibility and efficacy of porcine skin collagen (Pelvicol) implant by the transobturator route for the treatment of anterior vaginal wall prolapse. PATIENTS AND METHODS:Twenty-seven women with stage III or IV prolapse underwent anterior vaginal wall repair with porcine skin collagen implantat...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2003.09.005

    authors: Salomon LJ,Detchev R,Barranger E,Cortez A,Callard P,Darai E

    更新日期:2004-02-01 00:00:00

  • Double-J ureteral stents: an alternative to external urinary stents in orthotopic bladder substitution.

    abstract:OBJECTIVE:The aim of this study was to compare advantages and disadvantages of using double-J or external stents to preserve the uretero-ileal anastomosis in patients receiving an orthotopic neobladder. METHODS:77 consecutive patients with bladder cancer who underwent radical cystoprostatectomy and Studer neobladder w...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000052506

    authors: Micali S,De Carli P,Miano R,O'Sullivan D,Lamanna L,Micali F

    更新日期:2001-05-01 00:00:00

  • Interferon-alpha suppresses the antiapoptotic effect of NF-kB and sensitizes renal cell carcinoma cells in vitro to chemotherapeutic drugs.

    abstract:BACKGROUND:Immunochemotherapy (ICT) with interleukin-2 (IL-2) and interferon-alpha (IFNalpha) with a secondary effector (5-fluorouracil, 5 FU) is the only promising treatment for advanced renal cell carcinoma (RCC). With IFNalpha, besides the activation mechanisms of the immunosystem, a direct antitumor effect on tumor...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000052489

    authors: Steiner T,Junker U,Henzgen B,Nuske K,Durum SK,Schubert J

    更新日期:2001-04-01 00:00:00

  • Effect of lectins on 3H-uridine and 3H-thymidine uptake by cultured renal cell carcinoma and normal renal cells.

    abstract::The effect of lectins on cultured renal cell carcinoma and normal renal cells was studied. Ricin II showed effective inhibition of 3H-uridine and 3H-thymidine uptake by renal cell carcinoma and normal renal cells in all cases. Normal renal cells were more resistant to the inhibitory effect of ricin II as compared to r...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000472595

    authors: Bazeed MA,Becht E,Schärfe T,Schmidt J,Jacobi GH,Thüroff JW

    更新日期:1986-01-01 00:00:00

  • Prognostic factors for response to sildenafil in patients with erectile dysfunction.

    abstract:OBJECTIVE:To assess the clinical efficacy of sildenafil as treatment for erectile dysfunction (ED) the factors associated with treatment failure were investigated. METHODS:Open, prospective study including 244 patients suffering from ED who were evaluated by anamnesis, physical exploration, blood test, dynamic penile ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000049850

    authors: Martínez-Jabaloyas JM,Gil-Salom M,Villamón-Fort R,Pastor-Hernández F,Martínez-García R,García-Sisamón F

    更新日期:2001-12-01 00:00:00

  • Prognostic significance of bone metastases and bisphosphonate therapy in patients with renal cell carcinoma.

    abstract:BACKGROUND:Bone metastases (BMs) are frequently present in patients with metastatic renal cell carcinoma (mRCC) and cause significant morbidity. OBJECTIVE:The purpose of this analysis was to assess the impact of BMs and bisphosphonate therapy (BT) on outcomes in mRCC. DESIGN, SETTING, AND PARTICIPANTS:We conducted a ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2014.02.040

    authors: McKay RR,Lin X,Perkins JJ,Heng DY,Simantov R,Choueiri TK

    更新日期:2014-09-01 00:00:00

  • Minimal invasive therapy of prostatic abscess by transrectal ultrasound-guided perineal drainage.

    abstract::Prostatic abscess is a rare but severe disease. Conventional therapy is transurethral resection of the prostatic abscess. Since the advent of transrectal ultrasound (TRUS) a minimal-invasive treatment of prostatic abscess by TRUS-guided perineal drainage under local anesthesia is available. We report on our experience...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000475074

    authors: Bachor R,Gottfried HW,Hautmann R

    更新日期:1995-01-01 00:00:00

  • Osteocalcin gene HindIII C/T polymorphism is a biomarker for prostate cancer and responsiveness to hormone therapy.

    abstract:OBJECTIVES:Osteocalcin is a vitamin-K dependent protein which is related to the metabolism of bone and calcium. The formation or progression of prostate cancer is presumed to be associated with the osteocalcin gene. The most frequently seen polymorphism is HindIII which is located at the promoter region. HindIII is the...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/s0302-2838(02)00541-9

    authors: Wu HC,Lin CC,Chen WC,Chen HY,Tsai FJ

    更新日期:2003-02-01 00:00:00

  • Amino-terminal pro-C-type natriuretic peptide is associated with the presence, severity, and duration of vasculogenic erectile dysfunction.

    abstract:BACKGROUND:Endothelial dysfunction is a key event in the pathophysiology of erectile dysfunction (ED) and generalized vascular disease. C-type natriuretic peptide (CNP) is a paracrine molecule that effects endothelial integrity and vascular tone. OBJECTIVE:To determine the role of CNP in men with vasculogenic ED. DES...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.11.021

    authors: Vlachopoulos C,Ioakeimidis N,Terentes-Printzios D,Rokkas K,Aznaouridis K,Baou K,Bratsas A,Fassoulakis C,Stefanadis C

    更新日期:2009-09-01 00:00:00

  • Prostate specific antigen doubling time as auxiliary end point in hormone refractory prostatic carcinoma.

    abstract:OBJECTIVE:In hormone refractory prostatic carcinoma (HRPCa), the majority of patients have bone metastases only, which are by definition non-measurable. This makes objective evaluation of chemotherapeutic agents difficult. Prostate specific antigen (PSA) as a dynamic model was analyzed as potential auxiliary end point ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/s0302-2838(02)00539-0

    authors: Schmid HP,Morant R,Bernhard J,Maibach R,Swiss Group for Clinical Cancer Research (SAKK).

    更新日期:2003-01-01 00:00:00

  • EAU guidelines on iatrogenic trauma.

    abstract:CONTEXT:The European Association of Urology (EAU) Trauma Guidelines Panel presents an updated iatrogenic trauma section of their guidelines. Iatrogenic injuries are known complications of surgery to the urinary tract. Timely and adequate intervention is key to their management. OBJECTIVE:To assess the optimal evaluati...

    journal_title:European urology

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.eururo.2012.05.058

    authors: Summerton DJ,Kitrey ND,Lumen N,Serafetinidis E,Djakovic N,European Association of Urology.

    更新日期:2012-10-01 00:00:00

  • Clinical progress with a new antiandrogen, Casodex (bicalutamide).

    abstract::Casodex (bicalutamide, Zeneca Limited) is a nonsteroidal competitive inhibitor of androgens at the androgen receptor. The drug was developed to fulfil a number of needs for the treatment of prostate cancer. The specific aim was to demonstrate pharmacological activity, which would translate into clinical efficacy, good...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1159/000473847

    authors: Blackledge GR

    更新日期:1996-01-01 00:00:00

  • Hybrid transvaginal nephrectomy.

    abstract::This case study reports one case of transvaginal natural orifice transluminal endoscopic surgery (NOTES) in a 23-yr-old woman with right flank pain and recurrent urinary tract infection due to a nonfunctional right kidney. She underwent nephrectomy by transvaginal NOTES using the endoscope by vaginal access and two ad...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2007.10.053

    authors: Branco AW,Branco Filho AJ,Kondo W,Noda RW,Kawahara N,Camargo AA,Stunitz LC,Valente J,Rangel M

    更新日期:2008-06-01 00:00:00

  • Chemical analysis of renal stones from 377 Belgian patients by using qualitative or quantitative methods.

    abstract::The renal stones of 377 patients from the Brussels' area have been studied by chemical methods; 239 stones were submitted to qualitative analysis and the other 138 to a quantitative analysis. The results of the study demonstrate that, in Belgium as well as in other Western countries like the USA and Great Britain, cal...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473919

    authors: Fuss M,Simon J,Verbeelen D,Weiser M,Van Landuyt P,Elskens I

    更新日期:1978-01-01 00:00:00

  • Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations.

    abstract:BACKGROUND:The genomic features underpinning renal cell carcinoma with sarcomatoid dedifferentiation (sRCC) are not well understood, and at present, there are no specific or effective therapies for sRCC. OBJECTIVE:To identify genomic alterations in patients with sRCC. DESIGN, SETTING, AND PARTICIPANTS:We conducted ge...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.01.051

    authors: Malouf GG,Ali SM,Wang K,Balasubramanian S,Ross JS,Miller VA,Stephens PJ,Khayat D,Pal SK,Su X,Sircar K,Tamboli P,Jonasch E,Tannir NM,Wood CG,Karam JA

    更新日期:2016-08-01 00:00:00

  • The bacteriology of operated renal stones.

    abstract::In a group of patients consecutively operated on for renal stones, more than half of the patients had urinary tract infection. In a significant number of the patients with infection stones containing magnesium ammonium phosphate, no urease-producing microorganism could be cultured. Escherichia coli was on the other ha...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000464001

    authors: Bratell S,Brorson JE,Grenabo L,Hedelin H,Pettersson S

    更新日期:1990-01-01 00:00:00

  • A systematic review and meta-analysis on the use of phosphodiesterase 5 inhibitors alone or in combination with α-blockers for lower urinary tract symptoms due to benign prostatic hyperplasia.

    abstract:CONTEXT:Several randomized controlled trials (RCTs) on phosphodiesterase type 5 inhibitors (PDE5-Is) have showed significant improvements in both lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) in men affected by one or both conditions, without a significant increase in adverse events. However, the re...

    journal_title:European urology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.eururo.2012.02.033

    authors: Gacci M,Corona G,Salvi M,Vignozzi L,McVary KT,Kaplan SA,Roehrborn CG,Serni S,Mirone V,Carini M,Maggi M

    更新日期:2012-05-01 00:00:00

  • Our experience with retroperitoneal and transperitoneal laparoscopic pyeloplasty for pelvi-ureteric junction obstruction.

    abstract:OBJECTIVE:Laparoscopic dismembered pyeloplasty has been quoted to have equivalent success rates to the traditional open procedure in the treatment of pelvi-ureteric junction obstruction (PUJO). The aim of this study was to report our experience with laparoscopic pyeloplasty. PATIENTS AND METHODS:All patients with PUJO...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2005.08.004

    authors: Davenport K,Minervini A,Timoney AG,Keeley FX Jr

    更新日期:2005-12-01 00:00:00

  • Value of duplex Doppler ultrasonography in renal colic.

    abstract:OBJECTIVES:The aim of our study was to determine the value of duplex Doppler ultrasonography (DDU) in the patients' evolution with renal colic. The study of the resistive index (RI), difference of the RI (ARI) associated with a DDU intravesical recording (ureteral jets) were compared with renographic findings in renal ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/s0302-2838(01)00005-7

    authors: Geavlete P,Georgescu D,Cauni V,Niţa G

    更新日期:2002-01-01 00:00:00

  • Impact of urinary tract infection and detrusor pressure on renal tubular function in patients with vesicoureteral reflux.

    abstract:OBJECTIVE:The aim of this study was to evaluate prospectively the impact of bacteriuria with or without pyuria and/or detrusor pressure on renal tubular function in patients with secondary vesicoureteral reflux. METHODS:From October 1994 to December1998, we evaluated 54 patients with secondary vesicoureteral reflux (2...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000052464

    authors: Everaert K,Van Laecke E,Dekuyper P,Hoebeke P,Delanghe J,Oosterlinck W,Vande Walle J

    更新日期:2001-03-01 00:00:00

  • The methodology of corpus cavernosum electromyography revisited.

    abstract:OBJECTIVE:The methodology of corpus cavernosum electromyography (CC-EMG) was revisited, in order to overcome current methodological difficulties that hinder its clinical application. MATERIALS AND METHODS:Using an 8-channel device, CC-EMG was performed in 12 healthy volunteers. Surface electrodes were placed bilateral...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2004.04.002

    authors: Jiang XG,Wijkstra H,Meuleman EJ,Wagner G

    更新日期:2004-09-01 00:00:00

  • Topographical anatomy of periprostatic and capsular nerves: quantification and computerised planimetry.

    abstract:BACKGROUND:The exact distribution of periprostatic autonomic nerves is under debate. OBJECTIVE:To study the topographical anatomy of autonomic nerves of the periprostatic tissue and the capsule of the prostate (CAP). DESIGN, SETTING, AND PARTICIPANTS:Whole-mount sections of 30 prostates from patients having undergone...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.04.018

    authors: Ganzer R,Blana A,Gaumann A,Stolzenburg JU,Rabenalt R,Bach T,Wieland WF,Denzinger S

    更新日期:2008-08-01 00:00:00

  • Control of prostate cancer by transrectal HIFU in 227 patients.

    abstract:PURPOSE:To evaluate the results of high-intensity focused ultrasound (HIFU) treatment of localized prostate cancer with reference to disease-related prognostic factors. MATERIALS AND METHODS:Patients with T1-2 localized prostate cancers, prostate specific antigen (PSA)

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2006.04.012

    authors: Poissonnier L,Chapelon JY,Rouvière O,Curiel L,Bouvier R,Martin X,Dubernard JM,Gelet A

    更新日期:2007-02-01 00:00:00

  • Improved Reporting of Randomized Controlled Trials in the Urologic Literature.

    abstract:BACKGROUND:Well-designed randomized controlled trials (RCTs) have the potential to provide high-quality evidence to inform questions of therapy and prevention, but this potential is contingent on the use of appropriate methods and transparent reporting. OBJECTIVE:To systematically assess the quality of urology RCT rep...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2016.07.042

    authors: Narayan VM,Cone EB,Smith D,Scales CD Jr,Dahm P

    更新日期:2016-12-01 00:00:00

  • Serum levels of the carboxy-terminal propeptide of type I procollagen and the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen as markers of bone metastases in patients with prostate carcinoma.

    abstract:OBJECTIVES:To evaluate serum levels of the carboxy-terminal propeptide of type I procollagen (PICP) and the pyridinoline cross-linked carboxy-terminal telopeptide of type I collagen (ICTP) as possible markers of bone metastases in patients with prostate carcinoma (PCA) patients. METHODS:Levels of PICP and ICTP were me...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474454

    authors: Hosoya Y,Arai K,Honda M,Sumi S,Yoshida K

    更新日期:1997-01-01 00:00:00

  • Prevalence of and Risk Factors for Urinary Incontinence in Home Hospice Patients.

    abstract::Urinary incontinence (UI) is a debilitating and embarrassing condition that is prevalent among aging males and females. Little is known about UI in the home hospice setting. We sought to determine UI prevalence and risk factors in a cohort of 15432 home hospice patients over 4yr. Most of the study patients were female...

    journal_title:European urology

    pub_type: 信件

    doi:10.1016/j.eururo.2018.10.027

    authors: Chughtai B,Thomas D,Russell D,Bowles K,Prigerson H

    更新日期:2019-02-01 00:00:00

  • Metastatic potential in renal cell carcinomas ≤7 cm: Swedish Kidney Cancer Quality Register data.

    abstract:BACKGROUND:Renal cell carcinoma (RCC) represents 2-3% of all malignancies and accounts for approximately 90% of all kidney malignancies. An increasing proportion of RCCs are discovered incidentally, and the average tumor diameter at diagnosis has decreased over the last few decades. Small RCCs have often been regarded ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2011.06.029

    authors: Guðmundsson E,Hellborg H,Lundstam S,Erikson S,Ljungberg B,Swedish Kidney Cancer Quality Register Group.

    更新日期:2011-11-01 00:00:00