Interleukin 10 protects mice against staphylococcal enterotoxin B-induced lethal shock.

abstract：:Experiments were performed to investigate the usefulness of an enzyme-linked immunosorbent assay utilizing avidin-biotin interaction as a diagnostic tool for detection of Toxoplasma antigen in blood. The lower limit of sensitivity of the assay by this method was ca. 4 ng/ml, and standard assays provided a linear plot ...

journal_title：Infection and immunity

authors： Ise Y,Iida T,Sato K,Suzuki T,Shimada K,Nishioka K

更新日期：1985-04-01 00:00:00

abstract：:Investigating the innate immune response mediators released in milk has manifold implications, spanning from elucidation of the role played by mammary epithelial cells (MECs) in fighting microbial infections to the discovery of novel diagnostic markers for monitoring udder health in dairy animals. Here, we investigate...

journal_title：Infection and immunity

authors： Addis MF,Pisanu S,Marogna G,Cubeddu T,Pagnozzi D,Cacciotto C,Campesi F,Schianchi G,Rocca S,Uzzau S

更新日期：2013-09-01 00:00:00

abstract：:Hydrosalpinx induction in mice by Chlamydia muridarum infection, a model that has been used to study C. trachomatis pathogenesis in women, is known to depend on the cryptic plasmid that encodes eight genes designated pgp1 to pgp8. To identify the plasmid-encoded pathogenic determinants, we evaluated C. muridarum trans...

journal_title：Infection and immunity

authors： Liu Y,Huang Y,Yang Z,Sun Y,Gong S,Hou S,Chen C,Li Z,Liu Q,Wu Y,Baseman J,Zhong G

更新日期：2014-12-01 00:00:00

abstract：:Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in humans and has potential for use as a biological weapon. The genetic basis of the F. tularensis virulence is poorly understood. This study screened a total of 3,936 transposon mutants of the live vaccine strain for infection ...

journal_title：Infection and immunity

authors： Su J,Yang J,Zhao D,Kawula TH,Banas JA,Zhang JR

更新日期：2007-06-01 00:00:00

abstract：:Previous studies indicated that inorganic pyrophosphatase of Ascaris suum (AsPPase) plays an important role in larval survival in the host. Here we describe a precise role for AsPPase in larval molting and development and also describe the potential role of recombinant AsPPase (rAsPPase) in protective immunity to A. s...

journal_title：Infection and immunity

authors： Islam MK,Miyoshi T,Yamada M,Tsuji N

更新日期：2005-04-01 00:00:00

abstract：:The present study was performed to examine whether Porphyromonas gingivalis fimbriae induce specifically a protein kinase-mediated phosphorylated protein that is involved in the mechanism of signal transduction. The fimbriae induced a 68-kDa phosphorylated protein (pp68) in a dose-dependent manner in mouse peritoneal ...

journal_title：Infection and immunity

authors： Murakami Y,Hanazawa S,Watanabe A,Naganuma K,Iwasaka H,Kawakami K,Kitano S

更新日期：1994-12-01 00:00:00

abstract：:We have previously demonstrated the existence of Klebsiella pneumoniae clinical isolates deficient in the lipopolysaccharide O side chain, the major factor for resistance to complement-mediated killing in this bacterial species. These isolates are complement resistant, and their mechanisms to resist complement were in...

journal_title：Infection and immunity

authors： Alvarez D,Merino S,Tomás JM,Benedí VJ,Albertí S

更新日期：2000-02-01 00:00:00

abstract：:Haemophilus ducreyi is resistant to killing by normal serum antibody and complement. We discovered an H. ducreyi outer membrane protein required for expression of serum resistance and termed it DsrA (for "ducreyi serum resistance A"). The dsrA locus was cloned, sequenced, and mutagenized. An isogenic mutant (FX517) of...

journal_title：Infection and immunity

authors： Elkins C,Morrow KJ Jr,Olsen B

更新日期：2000-03-01 00:00:00

abstract：:During the systemic phase of murine infection with Salmonella enterica serovar Typhimurium, bacterial virulence is correlated with the ability to grow and survive within host macrophages. Salmonella pathogenicity island 2 (SPI-2), encoding a type three secretion system, has emerged as an important contributor to Salmo...

journal_title：Infection and immunity

authors： Linehan SA,Rytkönen A,Yu XJ,Liu M,Holden DW

更新日期：2005-07-01 00:00:00

abstract：:Antimicrobial peptides play an important role in host defense against Vibrio cholerae Generally, the V. cholerae O1 classical biotype is polymyxin B (PB) sensitive and El Tor is relatively resistant. Detection of classical biotype traits like the production of classical cholera toxin and PB sensitivity in El Tor strai...

journal_title：Infection and immunity

authors： Samanta P,Mandal RS,Saha RN,Shaw S,Ghosh P,Dutta S,Ghosh A,Imamura D,Morita M,Ohnishi M,Ramamurthy T,Mukhopadhyay AK

更新日期：2020-04-20 00:00:00

abstract：:Purified group A streptococcal peptidoglycan-polysaccharide (PG-PS) fragments were either de-O-acylated, or acetylated and then de-O-acylated to yield N-acetylated PG-PS. Native PG-PS was poorly degraded, N-acetylated PG-PS was extensively degraded, and de-O-acylated PG-PS was only slightly degraded by hen egg white l...

journal_title：Infection and immunity

authors： Stimpson SA,Lerch RA,Cleland DR,Yarnall DP,Clark RL,Cromartie WJ,Schwab JH

更新日期：1987-01-01 00:00:00

abstract：:Several strains of group B Streptococcus agalactiae were found to be lethal for young adult rats. When bacteria were heat killed and then injected intraperitoneally into rats, rapid death (14 to 18 h) of the rats occurred, characterized by labored breathing, hemolyzed serum, hemoglobinuria, and subungual hemorrhages. ...

journal_title：Infection and immunity

authors： Warejcka DJ,Goodrum KJ,Spitznagel JK

更新日期：1985-05-01 00:00:00

abstract：:Antiserum and purified immunoglobulin directed against Mycoplasma pneumoniae membrane protein P1 were examined for their influence on mycoplasma viability, metabolism, and cytadsorption. Anti-P1 immunoglobulin inhibited adherence of M. pneumoniae to hamster tracheal rings in vitro by up to 80% and inhibited hemadsorpt...

journal_title：Infection and immunity

authors： Krause DC,Baseman JB

更新日期：1983-03-01 00:00:00

abstract：:The reproducibility of an experimental result is a fundamental assumption in science. Yet, results that are merely confirmatory of previous findings are given low priority and can be difficult to publish. Furthermore, the complex and chaotic nature of biological systems imposes limitations on the replicability of scie...

journal_title：Infection and immunity

authors： Casadevall A,Fang FC

更新日期：2010-12-01 00:00:00

abstract：:A model of invasive Haemophilus influenzae type b disease in rats was used to compare the net in vivo and in vitro multiplication rates of this bacterium. In both the blood of rats and in vitro cultures (fresh rat blood or enriched broth) there was an exponential increase in the number of CFU per milliliter with calcu...

journal_title：Infection and immunity

authors： Rubin LG

更新日期：1986-06-01 00:00:00

abstract：:The efficacy of the innate immune system depends on its ability to mount an appropriate response to diverse infections and damaging agents. Key components of this system are pattern recognition receptors that detect pathogen-associated and damage-associated molecular patterns (PAMPs and DAMPs). Nlrp1b is a pattern rec...

journal_title：Infection and immunity

authors： Liao KC,Mogridge J

更新日期：2013-02-01 00:00:00

abstract：:Human monocytic ehrlichiosis (HME) is caused by a tick-borne obligate intracellular pathogen of the order Rickettsiales. HME disease can range from mild to a fatal, toxic shock-like syndrome, yet the mechanisms regulating pathogenesis are not well understood. We define a central role for type I interferons (alpha inte...

journal_title：Infection and immunity

authors： Zhang Y,Thai V,McCabe A,Jones M,MacNamara KC

更新日期：2014-04-01 00:00:00

abstract：:In general there is a poor correlation between serum lipopolysaccharide (LPS; the biologically active constituent of endotoxin) levels and mortality in septic patients. The objective of this study was to determine if chemical, structural, or biological differences among LPS from different clinical isolates of gram-neg...

journal_title：Infection and immunity

authors： Luchi M,Morrison DC

更新日期：2000-04-01 00:00:00

abstract：:Allergic-type immune responses, particularly immunoglobulin E (IgE), correlate with protective immunity in human schistosomiasis. To better understand the mechanisms of parasite elimination we examined the immune correlates of protection in baboons (Papio cynocephalus anubis), which are natural hosts for Schistosoma m...

journal_title：Infection and immunity

authors： Nyindo M,Kariuki TM,Mola PW,Farah IO,Elson L,Blanton RE,King CL

更新日期：1999-02-01 00:00:00

abstract：:Previous reports from our laboratory have shown that 7 days after infection of C3HeB/FeJ mice with an attenuated strain of Salmonella typhimurium, there is profound suppression of responses to B- and T-cell mitogens and suppression of the capacity of spleen cells to mount a primary, in vitro plaque-forming-cell (PFC) ...

journal_title：Infection and immunity

authors： Huang D,Schwacha MG,Eisenstein TK

更新日期：1996-09-01 00:00:00

abstract：:We investigated the cytokine/chemokine secretions and alteration of protein expression from peripheral blood mononuclear cells (PBMCs) cocultured with adult liver flukes (Opisthorchis viverrini) for 6 to 24 h. PBMC-derived proteins were identified by two-dimensional electrophoresis and mass spectrometry, and the cytok...

journal_title：Infection and immunity

authors： Hongsrichan N,Intuyod K,Pinlaor P,Khoontawad J,Yongvanit P,Wongkham C,Roytrakul S,Pinlaor S

更新日期：2014-05-01 00:00:00

abstract：:The influence of D-alanine and carbohydrate substitution of lipoteichoic acids (LTAs) on the binding of antibody directed to the polyglycerol phosphate (PGP) portion was found to be at least partially dependent upon the mode of presentation of the antigen. There were greater differences in binding of anti-PGP immunogl...

journal_title：Infection and immunity

authors： Kessler RE,Thivierge BH

更新日期：1983-08-01 00:00:00

abstract：:Strains Inaba 569B and Ogawa B1307 of Vibrio cholerae were grown in shaken Casamino Acids-yeast extract-glucose medium at 30 and 37 C for 4 days. Time courses of production of neuraminidase (NM), mucinase (MC), proteinase (PR), lytic factor (LF), and vascular permeability factor (PF) were compared by examining culture...

journal_title：Infection and immunity

authors： Kusama H,Craig JP

更新日期：1970-01-01 00:00:00

abstract：:The effect of a standard regimen of cimetidine on the gastric flora of 20 male volunteers was studied in a double-blind manner and compared with the effects of a standard antacid regimen. Postprandial microbial titers in gastric aspirates were significantly higher at 4, 8, and 16 weeks of therapy in subjects taking an...

journal_title：Infection and immunity

authors： Snepar R,Poporad GA,Romano JM,Kobasa WD,Kaye D

更新日期：1982-05-01 00:00:00

abstract：:Immune responses in the guinea pig model are understudied because of a lack of commercial reagents. We have developed a custom-made guinea pig oligonucleotide microarray (81 spots) and have examined the gene expression profile of splenocytes restimulated in vitro from Mycobacterium bovis BCG-vaccinated and naive anima...

journal_title：Infection and immunity

authors： Tree JA,Elmore MJ,Javed S,Williams A,Marsh PD

更新日期：2006-02-01 00:00:00

abstract：:The character of the antibody response in the rabbit to Salmonella typhimurium somatic (O) antigen was similar to the response to each of several serotypes of Shigella flexneri O antigens, namely a predominance of production of immunoglobulin M (IgM) antibody. Lipopolysaccharide protein (LPSP) and lipopolysaccharide (...

journal_title：Infection and immunity

authors： Fukazawa Y,Shinoda T,Yomoda T,Tsuchiya T

更新日期：1970-03-01 00:00:00

abstract：:F344 rats chronically infected with Ureaplasma parvum develop two distinct profiles: asymptomatic urinary tract infection (UTI) and UTI complicated by struvite urolithiasis. To identify factors that affect disease outcome, we characterized the temporal host immune response during infection by histopathologic analysis ...

journal_title：Infection and immunity

authors： Reyes L,Alvarez S,Allam A,Reinhard M,Brown MB

更新日期：2009-10-01 00:00:00

abstract：:Slime production is not a generally recognized feature of Staphylococcus epidermidis. In a recent outbreak of S. epidermidis intravascular catheter-associated sepsis, we noted that 63% of clinically implicated strains grew as a slimy film coating the culture tube walls when propagated in tryptic soy broth. Only 37% of...

journal_title：Infection and immunity

authors： Christensen GD,Simpson WA,Bisno AL,Beachey EH

更新日期：1982-07-01 00:00:00

abstract：:Pools of rat antiserum to Plasmodium berghei had different levels of protective activity as assessed by a passive transfer test. Preincubation of parasite inocula with an effective pool before injection did not significantly enhance protective activity. Removal of the antiserum from preincubated parasite inocula aboli...

journal_title：Infection and immunity

authors： Brown IN,Phillips RS

更新日期：1974-12-01 00:00:00

abstract：:Saccharomyces boulardii is a nonpathogenic yeast used in the treatment of Clostridium difficile diarrhea and colitis. We have reported that S. boulardii inhibits C. difficile toxin A enteritis in rats by releasing a 54-kDa protease which digests the toxin A molecule and its brush border membrane (BBM) receptor (I. Cas...

journal_title：Infection and immunity

authors： Castagliuolo I,Riegler MF,Valenick L,LaMont JT,Pothoulakis C

更新日期：1999-01-01 00:00:00