Porphyromonas gingivalis fimbriae induce a 68-kilodalton phosphorylated protein in macrophages.

abstract：:Protection against infection with virulent blood (trypomastigote) forms of Trypanosoma cruzi was accomplished in mice by immunization with culture (mainly epimastigote) forms killed by treatment with sodium perchlorate. Sodium chloride, used instead of sodium perchlorate, with all other conditions kept the same, faile...

journal_title：Infection and immunity

authors： Kierszenbaum F,Budzko DB

更新日期：1975-09-01 00:00:00

abstract：:Addition of a monoclonal antibody which binds the Cryptococcus neoformans capsule to suspensions of human monocytes, T lymphocytes, and cryptococcal cells (i) enhances interleukin-1beta (IL-1beta), tumor necrosis factor alpha, and IL-2 production; (ii) reduces IL-10 secretion; and (iii) promotes T-cell proliferation. ...

journal_title：Infection and immunity

authors： Vecchiarelli A,Retini C,Monari C,Casadevall A

更新日期：1998-03-01 00:00:00

abstract：:Adult murine models of Cryptosporidium infection involving Cryptosporidium muris and C. parvum were used to study immunity to cryptosporidiosis in the mammalian host. Immunocompetent BALB/c or C57BL/6 mice developed a highly patent infection with the RN 66 strain of C. muris but overcame the infection and were immune ...

journal_title：Infection and immunity

authors： McDonald V,Deer R,Uni S,Iseki M,Bancroft GJ

更新日期：1992-08-01 00:00:00

abstract：:Chemokines (CK) are potent leukocyte activators and chemoattractants and aid in granuloma formation, functions critical for the immune response to Mycobacterium tuberculosis. We hypothesized that infection of alveolar macrophages (AM) with different strains of M. tuberculosis elicits distinct profiles of CK, which cou...

journal_title：Infection and immunity

authors： Saukkonen JJ,Bazydlo B,Thomas M,Strieter RM,Keane J,Kornfeld H

更新日期：2002-04-01 00:00:00

abstract：:A variant enterotoxin gene, referred to as sezA+, has been identified. Staphylococcus aureus FRI1106, a staphylococcal enterotoxin type D producer (Sed+), contained HindIII fragments of 3.8 and 9.4 kilobase pairs (kbp) that hybridized in Southern blot analysis to a probe containing only staphylococcal enterotoxin type...

journal_title：Infection and immunity

authors： Soltis MT,Mekalanos JJ,Betley MJ

更新日期：1990-06-01 00:00:00

abstract：:Antiserum to a synthetic peptide, CTP3, consisting of residues 50 to 64 of the B subunit of cholera enterotoxin (CT), a sequence which is conserved in heat-labile enterotoxins from Escherichia coli strains of human (H-LT) or porcine (P-LT) origin, cross-reacted with and neutralized all three enterotoxins. It also cros...

journal_title：Infection and immunity

authors： Jacob CO,Arnon R,Finkelstein RA

更新日期：1986-05-01 00:00:00

abstract：:Female LSH hamsters infected with Treponema pallidum subsp, endemicum before pregnancy or during early pregnancy transmit a form of syphilis to the fetus that is similar to human congenital syphilis. The offspring develops rhinitis, skin rash, failure to thrive, and hepatosplenomegaly. T. pallidum is detectable in the...

journal_title：Infection and immunity

authors： Kajdacsy-Balla A,Howeedy A,Bagasra O

更新日期：1993-08-01 00:00:00

abstract：:Nonimmune binding of immunoglobulin to whole bacteria was quantitated for North American isolates of Haemophilus somnus recovered from cattle with pneumonia, reproductive failure (abortion), or thromboembolic meningoencephalitis or from the vagina or prepuce of carrier cattle. Quantitative binding activity covered a w...

journal_title：Infection and immunity

authors： Widders PR,Dorrance LA,Yarnall M,Corbeil LB

更新日期：1989-02-01 00:00:00

abstract：:To explore the molecular basis of the T-cell-mediated immune response to Listeria monocytogenes, we cloned and expressed listerial antigens in Escherichia coli using the lambda-ZAP bacteriophage and Bluescript plasmid vectors. A two-stage screening strategy was implemented to identify T-cell-reactive antigens; the fir...

journal_title：Infection and immunity

authors： Beattie IA,Swaminathan B,Ziegler HK

更新日期：1990-09-01 00:00:00

abstract：:Organisms of the Mycobacterium avium complex are associated with disseminated infection in patients with AIDS. The mechanisms that account for the survival of the intracellular bacteria are unknown. We document here that infection of C57BL/6 black mice with M. avium 101 triggered interleukin-10 (IL-10) production. The...

journal_title：Infection and immunity

authors： Bermudez LE,Champsi J

更新日期：1993-07-01 00:00:00

abstract：:Oral inoculation of calves and steers with 10(10) CFU of Escherichia coli O157:H7 induced prompt and sustained increases in serum antibodies to O157 lipopolysaccharide. Neutralizing antibodies to verotoxin 1 also increased rapidly in most steers but more gradually in calves. None of the animals developed neutralizing ...

journal_title：Infection and immunity

authors： Johnson RP,Cray WC Jr,Johnson ST

更新日期：1996-05-01 00:00:00

abstract：:The mammalian host response to infection includes the production and secretion of antimicrobial peptides from phagocytes and epithelial cells. Protegrins, a group of broadly microbicidal peptides isolated originally from porcine neutrophil lysates, were found to be stored as inactive proforms in porcine neutrophil gra...

journal_title：Infection and immunity

authors： Shi J,Ganz T

更新日期：1998-08-01 00:00:00

abstract：:Staphylococcus aureus is an important opportunistic pathogen and is the etiological agent of many hospital- and community-acquired infections. The golden pigment, staphyloxanthin, of S. aureus colonies distinguishes it from other staphylococci and related Gram-positive cocci. Staphyloxanthin is the product of a series...

journal_title：Infection and immunity

authors： Hall JW,Yang J,Guo H,Ji Y

更新日期：2017-01-26 00:00:00

abstract：:In Shigella flexneri a 220-kilobase plasmid encodes the ability to invade nonprofessional phagocytes by a mechanism similar to phagocytosis. In this report, the continuous macrophage cell line J774 was used to study the intracellular fate of both invasive and noninvasive strains. pWR100, the virulence plasmid of S. fl...

journal_title：Infection and immunity

authors： Clerc PL,Ryter A,Mounier J,Sansonetti PJ

更新日期：1987-03-01 00:00:00

abstract：:Glycosylation of the flagellar core proteins (FlaBs) was detected in Treponema pallidum Nichols and in the type or reference strains of seven oral Treponema species. In several nonmotile strains of oral treponemes, the FlaBs were undetectable by both antibody and glycan staining. In contrast, a spontaneous low-motilit...

journal_title：Infection and immunity

authors： Wyss C

更新日期：1998-12-01 00:00:00

abstract：:The hagfish, Eptatretus stoutii, has been shown to synthesize bactericidal antibodies after injections of gram-negative organisms. These bactericidins could be detected as early as 2 days after the primary injection. Secondary responses were accelerated, although titers were not significantly higher than those reached...

journal_title：Infection and immunity

authors： Acton RT,Weinheimer PF,Hildemann WH,Evans EE

更新日期：1971-08-01 00:00:00

abstract：:Strains of indigenous Escherichia coli, Bacteroides, and Lactobacillus were isolated from the gastrointestinal tracts of specific pathogen-free (SPF) mice. Nonvaccinated SPF mice exhibited in their spleens low numbers of plaque-forming cells (PFC) and rosette-forming cells reacting with antigens of these andigenous ba...

journal_title：Infection and immunity

authors： Berg RD,Savage DC

更新日期：1975-02-01 00:00:00

abstract：:Immunocompromised patients are more susceptible to recurrent nontyphoidal Salmonella (NTS) bacteremia. A key manifestation of HIV infection is the loss of CD4 T cells, which are crucial for immunity to Salmonella infection. We characterized the consequences of CD4 T cell depletion in mice where virulent Salmonella est...

journal_title：Infection and immunity

authors： Loomis WP,Delaney MA,Johnson ML,Cookson BT

更新日期：2020-12-15 00:00:00

abstract：:P6, a 16,600-dalton protein present in the outer membranes of both typeable and nontypeable strains, may be an important antigen in immunity to Haemophilus influenzae. The gene encoding P6 of a nontypeable strain of H. influenzae was cloned by using bacteriophage lambda gt11. Four recombinant phages were detected by s...

journal_title：Infection and immunity

authors： Nelson MB,Apicella MA,Murphy TF,Vankeulen H,Spotila LD,Rekosh D

更新日期：1988-01-01 00:00:00

abstract：:Assembly of adherent biofilms is the key mechanism involved in Staphylococcus epidermidis virulence during device-associated infections. Aside from polysaccharide intercellular adhesin (PIA), the accumulation-associated protein Aap and the extracellular matrix binding protein Embp act as intercellular adhesins, mediat...

journal_title：Infection and immunity

authors： Schommer NN,Christner M,Hentschke M,Ruckdeschel K,Aepfelbacher M,Rohde H

更新日期：2011-06-01 00:00:00

abstract：:Experimental infections of mice with the African trypanosome Trypanosoma brucei lead to a profound state of T-cell unresponsiveness in the lymph node cell (LNC) compartment. This suppression is mediated by macrophage-like cells which inhibit interleukin 2 (IL-2) secretion and down-regulate IL-2 receptor expression (M....

journal_title：Infection and immunity

authors： Darji A,Beschin A,Sileghem M,Heremans H,Brys L,De Baetselier P

更新日期：1996-06-01 00:00:00

abstract：:A cytoplasmic 75-kDa immunogen from Chlamydia trachomatis serovar L2 has previously been characterized as being similar to the Escherichia coli heat shock protein DnaK. We have localized a linear epitope for one monoclonal antibody specific for C. trachomatis DnaK. By use of a recombinant DNA technique, the epitope wa...

journal_title：Infection and immunity

authors： Birkelund S,Larsen B,Holm A,Lundemose AG,Christiansen G

更新日期：1994-05-01 00:00:00

abstract：:An inhibitory factor from Actinobacillus actinomycetemcomitans Y4 was isolated, and its properties indicated that it was a bacteriocin (actinobacillicin). The bacteriocin was active against Streptococcus sanguis strains, Streptococcus uberis (FDC1), and Actinomyces viscosus T14 as well as other strains of A. actinomyc...

journal_title：Infection and immunity

authors： Hammond BF,Lillard SE,Stevens RH

更新日期：1987-03-01 00:00:00

abstract：:Subchronic exposure to pharmacological levels of estrogenic compounds, including 17 beta-estradiol, diethylstilbestrol, and alpha-dienestrol, significantly increased the mortality of B6C3F1 female mice after Listeria infection. Compounds with little estrogenic activity, including 5 alpha-dihydrotestosterone, progester...

journal_title：Infection and immunity

authors： Pung OJ,Luster MI,Hayes HT,Rader J

更新日期：1984-11-01 00:00:00

abstract：:Levels of interferon in adult bovine serum and in fetal bovine serum and tissues were examined during the course of transplacental bovine viral diarrhea virus infection. The cows produced circulating interferon between 2 and 9 days after viral inoculation, with mean peak levels in the serum on day 4. Interferon could ...

journal_title：Infection and immunity

authors： Rinaldo CR Jr,Isackson DW,Overall JC Jr,Glasgow LA,Brown TT,Bistner SI,Gillespie JH,Scott FW

更新日期：1976-09-01 00:00:00

abstract：:Clostridium perfringens is an anaerobic, Gram-positive bacterium that causes a range of diseases in humans, including lethal gas gangrene. We have recently shown that strains of C. perfringens move across the surface of agar plates by a unique type IV pilus (TFP)-mediated social motility that had not been previously d...

journal_title：Infection and immunity

authors： Rodgers K,Arvidson CG,Melville S

更新日期：2011-08-01 00:00:00

abstract：:The induction of interleukin-8 (IL-8) in vitro has been suggested to correlate with the reactogenicity of Vibrio cholerae vaccine candidates. V. cholerae vaccine candidate 638, a hemagglutinin protease/hap-defective strain, was recently reported to be well tolerated in human volunteers, suggesting a role for Hap in re...

journal_title：Infection and immunity

authors： Zhou X,Gao DQ,Michalski J,Benitez JA,Kaper JB

更新日期：2004-01-01 00:00:00

abstract：:To evaluate the enteropathogenicity of Aeromonas hydrophila and Plesiomonas shigelloides, the rate of isolation of these organisms was compared among individuals with and without diarrhea in Thailand. In two groups of American travelers, A. hydrophila, but not P. shigelloides, was associated with episodes of travelers...

journal_title：Infection and immunity

authors： Pitarangsi C,Echeverria P,Whitmire R,Tirapat C,Formal S,Dammin GJ,Tingtalapong M

更新日期：1982-02-01 00:00:00

abstract：:Clostridium perfringens type B causes enteritis and enterotoxemia in domestic animals. By definition, these bacteria must produce alpha toxin (CPA), beta toxin (CPB) and epsilon toxin (ETX) although most type B strains also produce perfringolysin O (PFO) and beta2 toxin (CPB2). A recently identified Agr-like quorum-se...

journal_title：Infection and immunity

authors： Chen J,McClane BA

更新日期：2012-09-01 00:00:00

abstract：:Polymorphonuclear leukocytes from 46 adults (age 18 to 35), 19 adults (age 70 to 91), 10 children (age 1 to 3), and 22 neonates (cord blood samples) were tested for their chemiluminescence response to opsonized zymosan. Results indicated that both cord blood leukocytes and those from individuals over 70 were significa...

journal_title：Infection and immunity

authors： Van Epps DE,Goodwin JS,Murphy S

更新日期：1978-10-01 00:00:00