Sarcoptes scabiei: histopathological changes associated with acquisition and expression of host immunity to scabies.

Abstract:

:The sequential changes in the histology in scabietic lesions were investigated for hosts (rabbits) during sensitization and reinfestation with Sarcoptes scabiei. Experimentally infested naive hosts developed heavy scabies infestations but 65% of the hosts showed induced immunity (resistance) to reinfestation. All hosts (naive, immune, and susceptible) exhibited an initial cell infiltrate in scabietic lesions that consisted predominantly of neutrophils and a few macrophages. This was followed by a dense plasma cell infiltrate. Upon reinfestation the progression of neutrophil infiltration was faster and the response was greater in hosts who acquired immunity than those in the susceptible hosts.

journal_name

Exp Parasitol

authors

Arlian LG,Rapp CM,Vyszenski-Moher DL,Morgan MS

doi

10.1006/expr.1994.1005

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

51-63

issue

1

eissn

0014-4894

issn

1090-2449

pii

S0014489484710058

journal_volume

78

pub_type

杂志文章
  • Evaluation of stem aqueous extract and synthesized silver nanoparticles using Cissus quadrangularis against Hippobosca maculata and Rhipicephalus (Boophilus) microplus.

    abstract::The present study was to determine the efficacies of anti-parasitic activities of synthesized silver nanoparticles (Ag NPs) using stem aqueous extract of Cissus quadrangularis against the adult of hematophagous fly, Hippobosca maculata (Diptera: Hippoboscidae), and the larvae of cattle tick, Rhipicephalus (Boophilus) ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.06.009

    authors: Santhoshkumar T,Rahuman AA,Bagavan A,Marimuthu S,Jayaseelan C,Kirthi AV,Kamaraj C,Rajakumar G,Zahir AA,Elango G,Velayutham K,Iyappan M,Siva C,Karthik L,Rao KV

    更新日期:2012-10-01 00:00:00

  • In vitro anti-leishmanial efficacy of potato tuber extract (PTEx): leishmanial serine protease(s) as putative target.

    abstract::Leishmaniasis, a neglected tropical disease (NTD) causes major health problems in the tropical and subtropical world. Most of the antileishmanial modern therapies with different formulations of pentavalent antimonials, Miltefosine, Amphotericin B etc. are not satisfactory in recent times due to high toxicity to the ho...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2014.08.009

    authors: Paik D,Das P,De T,Chakraborti T

    更新日期:2014-11-01 00:00:00

  • Haemonchus contortus: molecular cloning, sequencing, and expression analysis of the gene coding for the small subunit of ribonucleotide reductase.

    abstract::Gastro-intestinal (GI) parasites are of great agricultural importance, annually costing the livestock industry vast amounts in resources to control parasitism. One such GI parasite, Haemonchus contortus, is principally pathogenic to sheep; with the parasite's blood-feeding behaviour causing effects ranging from mild a...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.08.001

    authors: Chen Y,Donald D,Savin K,Presidente PJ,Hartman D

    更新日期:2005-12-01 00:00:00

  • Morphological and quantitative aspects of nodule formation in hemolymph of the blowfly Chrysomya megacephala (Fabricius, 1794).

    abstract::Insects manifest effective immune responses that include both cellular and humoral components. Morphological and quantitative aspects of cellular and humoral cooperation during nodule formation in Chrysomya megacephala hemolymph against Saccharomyces cerevisae yeast cells were demonstrated for the first time. The anal...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2007.09.009

    authors: Faraldo AC,Gregório EA,Lello E

    更新日期:2008-03-01 00:00:00

  • Involvement of the Leishmania donovani virulence factor A2 in protection against heat and oxidative stress.

    abstract::Leishmania is an obligate intracellular protozoan parasite that infects cells of the reticulo-endothelial system. Host defences against Leishmania include fever and oxidant production, and the parasite has developed a number of defence mechanisms to neutralize the host response. The Leishmania donovani A2 family of pr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.06.001

    authors: McCall LI,Matlashewski G

    更新日期:2012-10-01 00:00:00

  • Plasmodium falciparum: D260, an intraerythrocytic parasite protein, is a member of the glutamic acid dipeptide-repeat family of proteins.

    abstract::Members of a serologically cross-reacting family of proteins including Ag332 and Pf11.1, megadalton proteins of schizont-infected red blood cells, and gametocytes, respectively, and Pf155-RESA, a 155-kDa protein of ring-infected red blood cells, have been reported to share amino acid repeat sequences. These repeats ar...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1995.1095

    authors: Barnes DA,Wollish W,Nelson RG,Leech JH,Petersen C

    更新日期:1995-08-01 00:00:00

  • Trypanosoma rangeli: Differential expression of cell surface polypeptides and ecto-phosphatase activity in short and long epimastigote forms.

    abstract::Trypanosoma rangeli is a parasite of a numerous wild and domestic animals, presenting wide geographical distribution and high immunological cross-reactivity with Trypanosoma cruzi, which may lead to misdiagnosis. T. rangeli has a complex life cycle, involving distinct morphological and functional forms in the vector. ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2005.11.015

    authors: Gomes SA,Fonseca de Souza AL,Silva BA,Kiffer-Moreira T,Santos-Mallet JR,Santos AL,Meyer-Fernandes JR

    更新日期:2006-04-01 00:00:00

  • Clonorchis sinensis: development and evaluation of a nested polymerase chain reaction (PCR) assay.

    abstract::Clonorchis sinensis is a fish-borne trematode endemic to East Asia, which infects over 35 million people globally. In the study described here, we developed a nested polymerase chain reaction (PCR) method for the specific and reliable detection of C. sinensis. The primers designed from the nucleotide sequence data der...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2006.09.010

    authors: Parvathi A,Sanath Kumar H,Kenchanna Prakasha B,Lu J,Xu X,Hu W,Feng Z,Karunasagar I,Karunasagar I

    更新日期:2007-03-01 00:00:00

  • A colorimetric method for the evaluation of anti-giardial drugs in vitro.

    abstract::The aim of this study was to develop a simple and reliable method to determine the viability of Giardia intestinalis after incubation with an anti-giardial agent by using a colorimetric method. Factors that may affect the optical density value were systematically evaluated. The most suitable conditions were obtained w...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2010.09.006

    authors: Hounkong K,Sawangjaroen N,Phongpaichit S

    更新日期:2011-02-01 00:00:00

  • Effect of giardiasis combined with low-protein diet on intestinal absorption of glucose and electrolytes in gerbils.

    abstract::Studies have shown that symptomatic infection by Giardia lamblia causes acute or chronic diarrhea, dehydration, abdominal pain and malabsorption, leading to undernutrition and weight loss. The aim of the present study was to evaluate the effects of giardiasis and its combination with a low-protein diet on the intestin...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.04.016

    authors: Gomes MA,de Oliveira DR,de Freitas SE,de Pinho Viana M,Borges EL

    更新日期:2012-08-01 00:00:00

  • Cryptosporidium parvum and Enterocytozoon bieneusi in American Mustangs and Chincoteague ponies.

    abstract::The prevalence of Cryptosporidium and microsporidia in feral horses, which have minimal contact with livestock and humans, is not currently known. We report the findings of a study on Cryptosporidium and microsporidia in 34 Mustangs and 50 Chincoteague ponies in the USA. Fecal samples were screened for presence of Cry...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2015.12.004

    authors: Wagnerová P,Sak B,McEvoy J,Rost M,Sherwood D,Holcomb K,Kváč M

    更新日期:2016-03-01 00:00:00

  • Molecular identification of Vermamoeba vermiformis from freshwater fish in lake Taal, Philippines.

    abstract::Free Living Amoebae (FLA) are considered ubiquitous. FLAs may infect various biological organisms which act as reservoir hosts. Infected freshwater fishes can pose a public health concern due to possible human consumption. This study aims to identify possible pathogenic FLAs present in freshwater fishes. Seventy five ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2017.09.009

    authors: Milanez GD,Masangkay FR,Thomas RC,Ordona MOGO,Bernales GQ,Corpuz VCM,Fortes HSV,Garcia CMS,Nicolas LC,Nissapatorn V

    更新日期:2017-12-01 00:00:00

  • Tick saliva regulates migration, phagocytosis, and gene expression in the macrophage-like cell line, IC-21.

    abstract::We studied the effects of tick saliva on cell migration, cell signaling, phagocytosis, and gene expression in the murine macrophage cell line, IC-21. Saliva increased both basal- and platelet-derived growth factor (PDGF)-stimulated migration in IC-21 cells. However, saliva did not affect PDGF-stimulated extracellular ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2010.11.012

    authors: Kramer CD,Poole NM,Coons LB,Cole JA

    更新日期:2011-03-01 00:00:00

  • Trypanosoma cruzi: effects of azadirachtin and ecdysone on the dynamic development in Rhodnius prolixus larvae.

    abstract::The effects of azadirachtin and ecdysone on the Trypanosoma cruzi population in the Rhodnius prolixus gut were investigated. T. cruzi were rarely found in the gut compartments of azadirachtin-treated larvae. High parasite numbers were observed in the stomach of the control and ecdysone groups until 10 days after treat...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.05.005

    authors: Cortez MR,Provençano A,Silva CE,Mello CB,Zimmermann LT,Schaub GA,Garcia ES,Azambuja P,Gonzalez MS

    更新日期:2012-07-01 00:00:00

  • Plasmodium falciparum and Plasmodium berghei: effect of magnesium on the development of parasitemia.

    abstract::The in vitro growth of Plasmodium falciparum was reduced by 35 and 43% through high concentrations (5 mmole/liter) of magnesium in RPMI medium and magnesium-free medium, respectively, after 48 hr, whereas no significant inhibition could be observed under these conditions after 24 hr cultivation in the respective mediu...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1995.1023

    authors: Hess FI,Kilian A,Söllner W,Nothdurft HD,Pröll S,Löscher T

    更新日期:1995-03-01 00:00:00

  • Chryseobacterium indologenes and Chryseobacterium gleum interact and multiply intracellularly in Acanthamoeba castellanii.

    abstract::Chryseobacterium indologenes and Chryseobacterium gleum are Gram negative environmental bacteria that have been frequently reported to implicate in fatal nosocomial infections, such as bacteraemia and ventilator-associated pneumonia in immunocompromised individuals in the past decades. The interaction between Chryseob...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2020.107862

    authors: Lim WG,Tong T,Chew J

    更新日期:2020-02-19 00:00:00

  • Endosymbiotic Mycobacterium chelonae in a Vermamoeba vermiformis strain isolated from the nasal mucosa of an HIV patient in Lima, Peru.

    abstract::In March 2010, a 35 year-old HIV/AIDS female patient was admitted to hospital to start treatment with Highly Active Antiretroviral Therapy (HAART) since during a routine control a dramatic decrease in the CD4(+) levels was detected. At this stage, a nasal swab from each nostril was collected from the patient to includ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2014.02.014

    authors: Cabello-Vílchez AM,Mena R,Zuñiga J,Cermeño P,Martín-Navarro CM,González AC,López-Arencibia A,Reyes-Batlle M,Piñero JE,Valladares B,Lorenzo-Morales J

    更新日期:2014-11-01 00:00:00

  • Plasmodium berghei: partial purification and characterization of the mitochondrial cytochrome c oxidase.

    abstract::Mitochondria from a rodent malarial parasite (Plasmodium berghei) were successfully purified by differential centrifugation and 22% Percoll density gradient separation. The purified mitochondria from the erythrocytic stages of the parasite had a density of 1.05 and were found to be heterogeneous by transmission electr...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1993.1070

    authors: Krungkrai J,Krungkrai SR,Bhumiratana A

    更新日期:1993-09-01 00:00:00

  • Schistosoma mansoni: L-glutamate-induced contractions in isolated muscle fibers; evidence for a glutamate transporter.

    abstract::Schistosoma mansoni muscle fibers contract in response to L-glutamate in a dose-dependent manner (10(-6)-10(-3) M). L-aspartate and D-aspartate are likewise effective in eliciting contraction of the fibers. Mammalian glutamate receptor agonists produce little or no contraction at concentrations as high as 1 mM. In add...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1996.0129

    authors: Miller CL,Day TA,Bennett JL,Pax RA

    更新日期:1996-12-01 00:00:00

  • Diversity of Sarcocystis spp shed by opossums in Brazil inferred with phylogenetic analysis of DNA coding ITS1, cytochrome B, and surface antigens.

    abstract::Although few species of Sarcocystis are known to use marsupials of the genus Didelphis as definitive host, an extensive diversity of alleles of surface antigen genes (sag2, sag3, and sag4) has been described in samples of didelphid opossums in Brazil. In this work, we studied 25 samples of Sarcocystis derived from gas...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2016.02.008

    authors: Valadas SY,da Silva JI,Lopes EG,Keid LB,Zwarg T,de Oliveira AS,Sanches TC,Joppert AM,Pena HF,Oliveira TM,Ferreira HL,Soares RM

    更新日期:2016-05-01 00:00:00

  • Molecular mechanisms of host cell invasion by Trypanosoma cruzi.

    abstract::The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful infection, yet the relationship between these cellular events and clinical disease remains obscure. This review explores the process of cell invasio...

    journal_title:Experimental parasitology

    pub_type: 杂志文章,评审

    doi:10.1016/j.exppara.2010.06.023

    authors: Epting CL,Coates BM,Engman DM

    更新日期:2010-11-01 00:00:00

  • Production of MMP-9 and inflammatory cytokines by Trypanosoma cruzi-infected macrophages.

    abstract::Matrix metalloproteinases (MMPs) constitute a large family of Zn(2+) and Ca(2+) dependent endopeptidases implicated in tissue remodeling and chronic inflammation. MMPs also play key roles in the activation of growth factors, chemokines and cytokines produced by many cell types, including lymphocytes, granulocytes, and...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2014.09.003

    authors: de Pinho RT,da Silva WS,de Castro Côrtes LM,da Silva Vasconcelos Sousa P,de Araujo Soares RO,Alves CR

    更新日期:2014-12-01 00:00:00

  • Amblyomma americanum: physiochemical isolation of a protein derived from the tick salivary gland that is capable of inducing immune resistance in guinea pigs.

    abstract::Crude salivary gland derived proteins from Amblyomma americanum ticks were analyzed by physiochemical (gel filtration and ion exchange chromatography) and immunochemical guinea pig IgG1 (anti-tick immunoaffinity column) techniques for the presence of antigens responsible for the induction of host immune resistance res...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(86)90006-8

    authors: Brown SJ,Askenase PW

    更新日期:1986-08-01 00:00:00

  • Cysticidal activity of extracts and isolated compounds from Teloxys graveolens: In vitro and in vivo studies.

    abstract::In the search of new alternatives for neurocysticercosis treatment, the cysticidal activity of organic extracts of Teloxys graveolens was evaluated. The in vitro activity of hexane, ethyl acetate and methanol extracts against Taenia crassiceps cysts was tested and the selectivity index relative to human fibroblasts wa...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2015.06.001

    authors: Palomares-Alonso F,Rojas-Tomé IS,Juárez Rocha V,Palencia Hernández G,González-Maciel A,Ramos-Morales A,Santiago-Reyes R,González-Hernández IE,Jung-Cook H

    更新日期:2015-09-01 00:00:00

  • Toxoplasma gondii: the role of IFN-gamma, TNFRp55 and iNOS in inflammatory changes during infection.

    abstract::In order to examine the role of IFN-gamma, TNFRp55 and iNOS in inflammatory reaction during toxoplasmosis, IFN-gamma(-/-), TNFRp55(-/-) and iNOS(-/-) mice were experimentally infected with Toxoplasma gondii ME-49 strain. The organs of the mice were evaluated for histology and immunohistochemistry in detection of tissu...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2009.05.011

    authors: Silva NM,Vieira JC,Carneiro CM,Tafuri WL

    更新日期:2009-09-01 00:00:00

  • Plasmodium vivax: C-terminal diversity in the blood stage SERA genes from Indian field isolates.

    abstract::The burden of Plasmodium vivax malaria is huge in India, affecting a large population annually. Recent reports of P. vivax contributing to severe illness and death, makes vaccine research on P. vivax malaria, a high priority. Extent of sequence variation in antigen coding genes is known to be a major hurdle in vaccine...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2013.02.004

    authors: Rahul CN,Shiva Krishna K,Meera Bai N,Kumar V,Phadke S,Rajesh V

    更新日期:2013-05-01 00:00:00

  • Duplex qPCR for Leishmania species identification using lesion imprint on filter paper.

    abstract:BACKGROUND:American cutaneous leishmaniasis (ACL) is caused by different Leishmania parasites, which stimulate and direct the immune response against the infection. OBJECTIVE:To evaluate the TaqMan probe technology applicability to diagnose and identifying of Leishmania spp. related to the ACL etiology. METHODOLOGY:T...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2020.108019

    authors: Morais RCS,Melo MGN,Goes TC,Pessoa E Silva R,Morais RF,Guerra JAO,Brito MEF,Brandão-Filho SP,Paiva Cavalcanti M

    更新日期:2020-12-01 00:00:00

  • The anthelmintic effect of plumbagin on Schistosoma mansoni.

    abstract::The anthelmintic effects of plumbagin (PB, 5-hydroxy-2-methyl-1,4-naphthoquinone) and praziquantel (PZQ) against adult Schistosoma mansoni in vitro were compared by estimating the relative motility (RM) values, survival indices (SI) and alterations of the tegument of flukes incubated in M-199 medium containing 1, 10 a...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/j.exppara.2012.10.003

    authors: Lorsuwannarat N,Saowakon N,Ramasoota P,Wanichanon C,Sobhon P

    更新日期:2013-01-01 00:00:00

  • Trypanosoma cruzi: molecular cloning of a gene coding for a putative vacuolar protein.

    abstract::We describe the characterization of Tc38, a Trypanosoma cruzi gene coding for a 337-amino-acid protein with a predicted molecular mass of 38 kDa. Tc38 presents similarities to the plant storage vacuolar protein gamma-3-hordein involved in the transport and targeting of prolamins to the vacuole of developing barley end...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1006/expr.1999.4485

    authors: Robello C,Dallagiovanna B,Castanys S,Gamarro F,Ehrlich R

    更新日期:2000-02-01 00:00:00

  • An experimental model of ameboma in guinea pig.

    abstract::Among the wide variety of clinicopathological manifestations of intestinal amebiasis, amebomas occur rarely and their pathogenesis is not well understood. When cholesterol-fed, 2- to 4-week-old guinea pigs were infected intracecally with a virulent, monoaxenic strain of Entamoeba histolytica, gross and histologically ...

    journal_title:Experimental parasitology

    pub_type: 杂志文章

    doi:10.1016/0014-4894(92)90151-y

    authors: Bhatti HS,Bhushnurmath S,Mahajan RC,Ganguly NK,Sehgal R

    更新日期:1992-05-01 00:00:00