Saccharomyces boulardii inhibits secretagogue-mediated adenosine 3',5'-cyclic monophosphate induction in intestinal cells.

abstract：BACKGROUND & AIMS:Polymorphisms in the region of the interleukin (IL)-28B gene on chromosome 19 have been associated with peginterferon-alfa-induced clearance of genotype 1 hepatitis C virus (HCV); there are no data for patients with genotype 2 or 3 HCV. We evaluated the effects of IL-28B polymorphisms on response to t...

journal_title：Gastroenterology

authors： Mangia A,Thompson AJ,Santoro R,Piazzolla V,Tillmann HL,Patel K,Shianna KV,Mottola L,Petruzzellis D,Bacca D,Carretta V,Minerva N,Goldstein DB,McHutchison JG

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND & AIMS:Nonalcoholic fatty liver disease (NAFLD) is a consequence of defects in diverse metabolic pathways that involve hepatic accumulation of triglycerides. Features of these aberrations might determine whether NAFLD progresses to nonalcoholic steatohepatitis (NASH). We investigated whether the diverse defe...

journal_title：Gastroenterology

authors： Alonso C,Fernández-Ramos D,Varela-Rey M,Martínez-Arranz I,Navasa N,Van Liempd SM,Lavín Trueba JL,Mayo R,Ilisso CP,de Juan VG,Iruarrizaga-Lejarreta M,delaCruz-Villar L,Mincholé I,Robinson A,Crespo J,Martín-Duce A,Romero-Gó

更新日期：2017-05-01 00:00:00

abstract：:Water and electrolyte transport were determined in rat ileum and colon using the single-pass perfusion technique. Intraperitoneal dopamine caused prompt stimulation of both ileal and colonic water absorption. The dopamine effect was mediated by both specific dopamine and alpha 2-adrenergic receptors. Haloperidol, a sp...

journal_title：Gastroenterology

authors： Donowitz M,Elta G,Battisti L,Fogel R,Label-Schwartz E

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND & AIMS:The aim of this study was to determine whether expression of hepatitis C virus proteins alters hepatic morphology or function in the absence of inflammation. METHODS:Transgenic C57BL/6 mice with liver-specific expression of RNA encoding the complete viral polyprotein (FL-N transgene) or viral structu...

journal_title：Gastroenterology

authors： Lerat H,Honda M,Beard MR,Loesch K,Sun J,Yang Y,Okuda M,Gosert R,Xiao SY,Weinman SA,Lemon SM

更新日期：2002-02-01 00:00:00

abstract：:Liver disease with inclusions of copper was recognized among 30 rural workers with "vineyard sprayer's lung." The pathological findings were varied: focal or diffuse swelling and proliferation of Kupffer cells; histiocytic and sarcoid-like granulomata; fibrosis of variable degree in the perisinusoidal, portal, and sub...

journal_title：Gastroenterology

authors： Pimentel JC,Menezes AP

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND & AIMS:Predictors of reactivation of hepatitis B following hepatitis B e antigen (HBeAg) seroconversion in chronic hepatitis B have rarely been reported before and deserve further study. METHODS:A total of 133 HBeAg-positive asymptomatic carriers who have undergone HBeAg seroconversion were studied. Reactiv...

journal_title：Gastroenterology

authors： Chu CM,Liaw YF

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND & AIMS:The host immune response during the chronic phase of hepatitis C virus infection varies among individuals; some patients have a no interferon (IFN) response in the liver, whereas others have full activation of IFN-stimulated genes (ISGs). Preactivation of this endogenous IFN system is associated with ...

journal_title：Gastroenterology

authors： Dill MT,Duong FH,Vogt JE,Bibert S,Bochud PY,Terracciano L,Papassotiropoulos A,Roth V,Heim MH

更新日期：2011-03-01 00:00:00

abstract：:We have greatly advanced our ability to grow a diverse range of tissue-derived and pluripotent stem cell-derived gastrointestinal (GI) tissues in vitro. These systems, broadly referred to as organoids, have allowed the field to move away from the often nonphysiological, transformed cell lines that have been used for d...

journal_title：Gastroenterology

authors： Dedhia PH,Bertaux-Skeirik N,Zavros Y,Spence JR

更新日期：2016-05-01 00:00:00

abstract：:We studied the response of lymphocytes from 43 patients with inflammatory bowel disease to allogeneic stimulation in one-way mixed-lymphocyte cultures. We found that 53% of patients with inflammatory bowel disease, in contrast to 4% of normal and disease controls, had significant depression of mixed-lymphocyte culture...

journal_title：Gastroenterology

authors： Fiske SC,Falchuk ZM

更新日期：1980-10-01 00:00:00

abstract：:Incidence of intrahepatic arteriovenous fistula after needle biopsy of the liver, percutaneous transhepatic cholangiography, and transhepatic catheterization of an intrahepatic bile duct or portal vein, was determined by studying the hepatic arteriograms obtained within 1 month of the transhepatic procedure. An arteri...

journal_title：Gastroenterology

authors： Okuda K,Musha H,Nakajima Y,Takayasu K,Suzuki Y,Morita M,Yamasaki T

更新日期：1978-06-01 00:00:00

abstract：:Cell-mediated immunity is impaired during cholestasis, and there is evidence that bile acids play a role in this immune defect. Ursodeoxycholic acid (UDCA), which corrects the immunological abnormalities observed in primary biliary cirrhosis, could counter the detrimental effects of the endogenous bile acids. Accordin...

journal_title：Gastroenterology

authors： Calmus Y,Weill B,Ozier Y,Chéreau C,Houssin D,Poupon R

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND & AIMS:Reactive oxidative species (ROS) are believed to be involved in the progression of nonalcoholic steatohepatitis (NASH). However, little is known about the sources of ROS in hepatocytes or their role in disease progression. We studied the effects of nicotinamide adenine dinucleotide phosphate reduced o...

journal_title：Gastroenterology

authors： Bettaieb A,Jiang JX,Sasaki Y,Chao TI,Kiss Z,Chen X,Tian J,Katsuyama M,Yabe-Nishimura C,Xi Y,Szyndralewiez C,Schröder K,Shah A,Brandes RP,Haj FG,Török NJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND/AIMS:Hepatic osmoreceptors are sensitive to changes in portal blood osmolality and cause variations in plasma antidiuretic hormone and water diuresis, which prevent major systemic osmotic changes. Insensitivity of hepatic osmoreceptors might contribute to maintaining increased plasma levels of antidiuretic h...

journal_title：Gastroenterology

authors： Castellano G,Solis-Herruzo JA,Gonzalez A,Morillas JD,Moreno D,Muñoz T,Larrodera L

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND & AIMS:Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has increased in incidence and severity, however, few stud...

journal_title：Gastroenterology

authors： Gutiérrez RL,Riddle MS,Porter CK

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND & AIMS:We recently showed that dietary supplementation with an analogue of 1alpha,25-dihydroxy-vitamin D3, 1alpha,25-dihydroxy-16-ene-23-yne-26,27 F6-vitamin D3 (RO24-5531), reduced the incidence of colonic tumors in rats treated with azoxymethane (AOM). The aim of this study was to determine whether alterat...

journal_title：Gastroenterology

authors： Wali RK,Bissonnette M,Khare S,Aquino B,Niedziela S,Sitrin M,Brasitus TA

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND & AIMS:Many putative pronucleating proteins have been isolated from the biliary concanavalin A (con A)-binding fraction. The pronase resistance of the overall nucleating-promoting activity was almost never taken into consideration. The aim of this study was to identify the major pronase-resistant con A-bindi...

journal_title：Gastroenterology

authors： Zijlstra AI,Offner GD,Afdhal NH,van Overveld M,Tytgat GN,Groen AK

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells (BECs) are considered to be a source of regenerating hepatocytes when hepatocyte proliferation is compromised. However, there is still controversy about the extent to which BECs can contribute to the regenerating hepatocyte population, and thereby to liver recovery. To investi...

journal_title：Gastroenterology

authors： Choi TY,Ninov N,Stainier DY,Shin D

更新日期：2014-03-01 00:00:00

abstract：:Because the esophagus is easily accessible with endoscopy, early diagnosis and curative treatment of esophageal cancer is possible. However, diagnosis is often delayed because symptoms are not specific during early stages of tumor development. The onset of dysphagia is associated with advanced disease, which has a sur...

journal_title：Gastroenterology

authors： di Pietro M,Canto MI,Fitzgerald RC

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND & AIMS:Transferrin receptor 2 (TfR2) plays a key role in the regulation of iron metabolism. Mutations of TfR2 in humans cause type 3 hereditary hemochromatosis. Although highly expressed in liver, several studies have reported TfR2 expression in other tissues. To determine the contribution of liver expressed...

journal_title：Gastroenterology

authors： Wallace DF,Summerville L,Subramaniam VN

更新日期：2007-01-01 00:00:00

abstract：:The effects of IV injection of 5-hydroxytryptamine 3 receptor antagonists (BRL 43694 and GR38032F) on gastrointestinal contractile activity were studied in dogs with vagally denervated fundic pouch in the conscious state by means of chronically implanted force transducers in the gastrointestinal tract and the pouch. I...

journal_title：Gastroenterology

authors： Itoh Z,Mizumoto A,Iwanaga Y,Yoshida N,Torii K,Wakabayashi K

更新日期：1991-04-01 00:00:00

abstract：:Most studies show that oral ingestion of iron does not cause a positive stool guaiac reaction. However, all in vitro studies show that iron does cause a positive guaiac reaction and some in vivo studies have shown a positive stool guaiac reaction in response to oral iron. This study examines this unresolved question. ...

journal_title：Gastroenterology

authors： McDonnell WM,Ryan JA,Seeger DM,Elta GH

更新日期：1989-01-01 00:00:00

abstract：:The effect of substance P (SP) on the release of gastric somatostatinlike immunoreactivity (SLI) was studied. Substance P inhibited both basal SLI release and SLI release stimulated by gastric inhibitory polypeptide or 1-isoproterenol. This inhibitory action of SP was not blocked by atropine or hexamethonium, suggesti...

journal_title：Gastroenterology

authors： Kwok YN,McIntosh CH,Pederson RA,Brown JC

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND & AIMS:High-carbohydrate diets with a high glycemic response may exacerbate the metabolic consequences of the insulin-resistance syndrome. The effect on the incidence of gallstone disease is not clear. METHODS:We examined the associations between high-carbohydrate diets with a high glycemic response and the...

journal_title：Gastroenterology

authors： Tsai CJ,Leitzmann MF,Willett WC,Giovannucci EL

更新日期：2005-07-01 00:00:00

abstract：:Gastric emptying of a solid meal and serum gastrin concentration were studied in 26 patients with duodenal ulcer disease before and after parietal cell vagotomy (PCV), selective gastric vagotomy with drainage (SGV + D), or parietal cell vagotomy with drainage. PCV had no significant effect on gastric emptying rate, wh...

journal_title：Gastroenterology

authors： Brandsborg O,Brandsborg M,Lovgreen NA,Mikkelsen K,Moller B,Rokkjaer M,Amdrup E

更新日期：1977-02-01 00:00:00

abstract：:Four patients who underwent transplantation for hepatitis B virus-related liver disease developed rapidly progressive liver failure attributable to recurrent hepatitis B disease typified by hyperbilirubinemia and distinctive hepatocyte ballooning and progressive fibrosis consistent with recently reported fibrosing cho...

journal_title：Gastroenterology

authors： Benner KG,Lee RG,Keeffe EB,Lopez RR,Sasaki AW,Pinson CW

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND & AIMS:Nonalcoholic fatty liver disease (NAFLD) is associated with increased risk of hepatic, cardiovascular, and metabolic diseases. High-protein diets, rich in methionine and branched chain amino acids (BCAAs), apparently reduce liver fat, but can induce insulin resistance. We investigated the effects of d...

journal_title：Gastroenterology

authors： Markova M,Pivovarova O,Hornemann S,Sucher S,Frahnow T,Wegner K,Machann J,Petzke KJ,Hierholzer J,Lichtinghagen R,Herder C,Carstensen-Kirberg M,Roden M,Rudovich N,Klaus S,Thomann R,Schneeweiss R,Rohn S,Pfeiffer AF

更新日期：2017-02-01 00:00:00

abstract：:Eosinophilic esophagitis (EoE) was historically distinguished from gastroesophageal reflux disease on the basis of histology and lack of responsiveness to acid suppressive therapy, but it is now appreciated that esophageal eosinophilia can respond to proton pump inhibitors. Genetic and environmental factors contribute...

journal_title：Gastroenterology

authors： Rothenberg ME

更新日期：2015-05-01 00:00:00

abstract：:Several compounds, in particular bile acids, undergo enterohepatic circulation (EHC). Limited data are available on the pathophysiologic aspects of this circulation. In the present study we describe a surgical technique in rats that allows a long-term, reversible interruption of the EHC and monitoring of peripheral bl...

journal_title：Gastroenterology

authors： Kuipers F,Havinga R,Bosschieter H,Toorop GP,Hindriks FR,Vonk RJ

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND & AIMS:After liver injury, bone marrow-derived liver sinusoidal endothelial cell progenitor cells (BM SPCs) repopulate the sinusoid as liver sinusoidal endothelial cells (LSECs). After partial hepatectomy, BM SPCs provide hepatocyte growth factor, promote hepatocyte proliferation, and are necessary for norma...

journal_title：Gastroenterology

authors： Wang L,Wang X,Wang L,Chiu JD,van de Ven G,Gaarde WA,Deleve LD

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND & AIMS:The emergence of oxyntic atrophy and metaplastic cell lineages in response to chronic Helicobacter pylori infection predisposes to gastric neoplasia. We have described a trefoil factor family 2 (TFF2; spasmolytic polypeptide) expressing metaplasia (SPEM) associated with gastric neoplasia in both roden...

journal_title：Gastroenterology

authors： Nomura S,Baxter T,Yamaguchi H,Leys C,Vartapetian AB,Fox JG,Lee JR,Wang TC,Goldenring JR

更新日期：2004-08-01 00:00:00